Professor Craig Jamieson

Publications

A framework for the biophysical screening of antibody mutations targeting solvent-accessible hydrophobic and electrostatic patches for enhanced viscosity profiles

Armstrong Georgina B, Shah Vidhi, Sanches Paula, Patel Mitul, Casey Ricky, Jamieson Craig, Burley Glenn A, Lewis William, Rattray Zahra

Computational and Structural Biotechnology Journal Vol 23, pp. 2345-2357 (2024)

https://doi.org/10.1016/j.csbj.2024.05.041

One-pot oxidative amidation of aldehydes via the generation of nitrile imine intermediates

Henry Martyn C, Minty Laura, Kwok Alexander C W, Elwood Jessica M L, Foulis Adam J, Pettinger Jonathan, Jamieson Craig

Journal of Organic Chemistry Vol 89, pp. 7913-7926 (2024)

https://doi.org/10.1021/acs.joc.4c00575

Development of a horizontal dynamically mixed flow reactor for laboratory scale-up of photochemical Wohl–Ziegler bromination

Pratley Cassie, Shaalan Youssef, Boulton Lee, Jamieson Craig, Murphy John A, Edwards Lee J

Organic Process Research and Development Vol 28, pp. 1725-1733 (2024)

https://doi.org/10.1021/acs.oprd.3c00348

Improving bi-specific engagement : assessing monovalent vs bivalent binding

Duxbury Rachel, Beveridge Rebecca, Jamieson Craig, Jones David, Jones Gavin, Rattray Zahra

2nd Annual GSK Biopharm Postgraduate Symposium (2024)

Synthesis and evaluation of small molecule inhibitors of the androgen receptor N-terminal domain

Henry Martyn C, Riley Christopher M, Hunter Irene, Elwood Jessica M L, Lopez-Fernandez J Daniel, Minty Laura, Coe Diane M, McEwan Iain J, Jamieson Craig

ACS Medicinal Chemistry Letters Vol 14, pp. 1800-1806 (2023)

https://doi.org/10.1021/acsmedchemlett.3c00426

Computer vision as a new paradigm for monitoring of solution and solid phase peptide synthesis

Yan Chunhui, Fyfe Calum, Minty Laura, Barrington Henry, Jamieson Craig, Reid Marc

Chemical Science Vol 14, pp. 11872-11880 (2023)

https://doi.org/10.1039/d3sc01383a

More publications

Research Interests

Biography

Craig Jamieson earned his BSc (Hons) in Chemistry at the University of Glasgow in 1996. His PhD studies were carried out under the direction of Professor R Ramage at the University of Edinburgh (1999).  Following postdoctoral research under the supervision of Professor S V Ley at the University of Cambridge, in 2001 he was appointed as a Principal Scientist in GlaxoSmithKline's Discovery Medicinal Chemistry group working on a range of exploratory medicinal chemistry programmes.  In 2004, Craig joined Organon Laboratories (later Merck Research Labs) as a Group Leader in the Medicinal Chemistry Department, with responsibility for hit to clincal candidate optimisation.  In August 2010, Craig was appointed as a John Anderson Research Lecturer in Chemical Biology, based in the Department of Pure and Applied Chemistry at the University of Strathclyde where he is currently a Professor in the Chemical Biology and Medicinal Chemistry Research Theme.

Research Interests

A major area of focus for our research continues to be in the Chemistry-Biology-Medicine continuum.  In this regard, we have a number of active programmes centred around hit and lead identification on disease targets and mechanisms in areas of significant societal need.  Allied to our work in the medicinal chemistry sphere, we also have a keen interest in the development of novel, enabling synthetic methodologies to enhance the armamentarium of molecule makers working in our arena.  We collaborate with groups and industrial partners locally, nationally and globally in order to effectively meet our research goals.

Professional Activities

Sequence engineering to improve syringeability of high concentration mAb formulations

Contributor

23/11/2022

Gyros Protein Technologies

Visiting researcher

1/6/2019

Almac Sciences

Visiting researcher

31/5/2019

Aldeyra Therapeutics Inc

Consultant

1/10/2018

Arc Scientific

Consultant

1/1/2016

Science Advances (Journal)

Peer reviewer

1/1/2014

More professional activities

Projects

A Prosperity Partnership for the Design of Next-Generation Antibody Drug Bioconjugates (Next-Gen ADC)

Burley, Glenn (Principal Investigator) Jamieson, Craig (Co-investigator) Kerr, William (Co-investigator) Nordon, Alison (Co-investigator) Rattray, Zahra (Co-investigator) Tomkinson, Nick (Co-investigator)

15-Jan-2023 - 14-Jan-2028

Developing new bioanalytical pipelines for early-stage assessment of antibody-drug conjugate developability

Rattray, Zahra (Principal Investigator) Jamieson, Craig (Co-investigator) Jolliffe, Sophie (Research Co-investigator)

02-Jan-2023 - 01-Jan-2027

Biopharmaceuticals - Investigating immune complex formation induced by bispecific antibody engagement with soluble target antigens.

Rattray, Zahra (Principal Investigator) Jamieson, Craig (Principal Investigator) Gauntlett, Ross William (Post Grad Student)

01-Jan-2023 - 31-Jan-2027

Industrial CASE Account - University of Strathclyde 2022 | McTaggart, Eilidh

Jamieson, Craig (Principal Investigator) Burley, Glenn (Co-investigator) McTaggart, Eilidh (Research Co-investigator)

01-Jan-2023 - 01-Jan-2027

NMR-BASE: Nuclear Magnetic Resonance for Biomolecule Analysis in Supported Environments

Parkinson, John (Principal Investigator) Burley, Glenn (Co-investigator) Dufès, Christine (Co-investigator) Irving, Craig (Co-investigator) Jamieson, Craig (Co-investigator) Scott, Fraser (Co-investigator) Seib, Philipp (Co-investigator) Taladriz Sender, Andrea (Co-investigator)

01-Jan-2023 - 31-Jan-2024

Industrial CASE Account - University of Strathclyde 2022 | Jackson, Cara

Beveridge, Rebecca (Principal Investigator) Jamieson, Craig (Co-investigator) Jackson, Cara (Research Co-investigator)

01-Jan-2022 - 01-Jan-2026

More projects