Prof Joop Ter Horst

Strathclyde Institute of Pharmacy and Biomedical Sciences

Personal statement

Joop ter Horst leads an application driven fundamental research group that will make a substantial contribution to the paradigm shift to continuous manufacturing in the pharmaceutical industry. The group will identify routes to exploit the fundamental principles relating molecule, crystal structure and crystallization process phenomena to the crystal product quality to come to hybrid separation technologies to be incorporated in the continuous pharmaceutical manufacturing chain. He adopts a view from the molecular level and up for gaining fundamental understanding to use in control and prediction of new industrial crystallization processes. He cooperates with many university groups inside and outside the UK and his research benefits many industrial partners. Joop ter Horst supervises 4 PhD students within CMAC and 2 at the TU Delft working on various crystallisation-related topics such as Crystal Nucleation, Continuous Crystallisation Start up & Steady State and Chiral Separation.

Publications

Towards deracemization in the absence of grinding through crystal transformation, ripening, and racemization
Xiouras Christos, Van Cleemput Emma, Kumpen Andries, Ter Horst Joop H., Van Gerven Tom, Stefanidis Georgios D.
Crystal Growth and Design Vol 17, pp. 882-890, (2017)
http://dx.doi.org/10.1021/acs.cgd.6b01758
Immobilization of gluten in spherical matrices of food-grade hydrogels
Reus Marloes A., Krintiras Georgios A., Stefanidis Georgios D., ter Horst Joop H., van der Heijden Antoine E. D. M.
Journal of Food Process Engineering, (2017)
http://dx.doi.org/10.1111/jfpe.12534
Solid separation from a mixed suspension through electric-field-enhanced crystallization
Li Wei, Radacsi Norbert, Kramer Herman J. M., van der Heijden Antoine E. D. M., ter Horst Joop H.
Angewandte Chemie Vol 55, pp. 16088-16091, (2016)
http://dx.doi.org/10.1002/anie.201609832
Prenucleation self-assembly and chiral discrimination mechanisms during solution crystallisation of racemic diprophylline
Brandel Clément, Cartigny Yohann, Coquerel Gérard, ter Horst Joop H., Petit Samuel
Chemistry - A European Journal Vol 22, pp. 16103-16112, (2016)
http://dx.doi.org/10.1002/chem.201602707
Deracemization of a racemic compound via its conglomerate-forming salt using temperature cycling
Li Wei W., Spix Laura, De Reus Saskia C A, Meekes Hugo, Kramer Herman J M, Vlieg Elias, ter Horst Joop H.
Crystal Growth and Design Vol 16, pp. 5563-5570, (2016)
http://dx.doi.org/10.1021/acs.cgd.6b01034
Solvates, salts, and cocrystals : a proposal for a feasible classification system
Grothe E., Meekes H., Vlieg E., Ter Horst J. H., De Gelder R.
Crystal Growth and Design Vol 16, pp. 3237-3243, (2016)
http://dx.doi.org/10.1021/acs.cgd.6b00200

more publications

Professional activities

External Examiner for the PhD student Jeroen Jordens in the group of Tom van Gerven
Member
5/7/2016
External Examiner for the PhD student Fanny George in the group of Tom Leyssens
Member
10/6/2016
5th Granada International School of Crystallization
Participant
29/5/2016
Crystallize COST Action CM1402 Annual Meeting
Participant
6/4/2016
Chirality, Enantiopurity and Crystallization
Member
21/3/2016
Promotor at the defence of my Delft PhD student Marloes Reus
Chair
18/3/2016

more professional activities

Projects

Doctoral Training Partnership (DTP 2016-2017 University of Strathclyde) | Moreno Leon, Carlos
Ter Horst, Joop (Principal Investigator) Roy, Sudipta (Co-investigator) Moreno Leon, Carlos (Research Co-investigator)
Period 01-Nov-2016 - 01-Nov-2019
Doctoral Training Centre In Continuous Manufacturing And Crystallisation | Olalere, Olayinka Hassan
Ter Horst, Joop (Principal Investigator) Florence, Alastair (Co-investigator) Olalere, Olayinka Hassan (Research Co-investigator)
Period 01-Oct-2015 - 01-Oct-2019
Doctoral Training Centre In Continuous Manufacturing And Crystallisation | Dunn, Andrew Steven
Ter Horst, Joop (Principal Investigator) Florence, Alastair (Co-investigator) Dunn, Andrew Steven (Research Co-investigator)
Period 01-Oct-2015 - 01-Oct-2019
Doctoral Training Partnership (DTP - University of Strathclyde) | Bebiano, Suse Vanessa
Oswald, Iain (Principal Investigator) Ter Horst, Joop (Co-investigator) Bebiano, Suse Vanessa (Research Co-investigator)
Period 01-Oct-2015 - 01-Apr-2019
Scaling up Viedma Ripening
Steendam, Rienk (Principal Investigator) Ter Horst, Joop (Principal Investigator)
Period 01-Jun-2016 - 01-Sep-2016
Analysis and Resolution of Chiral Compounds
Steendam, Rienk (Co-investigator) Ter Horst, Joop (Principal Investigator)
Period 01-Jun-2016 - 01-Sep-2016

more projects

Address

Strathclyde Institute of Pharmacy and Biomedical Sciences
Technology Innovation Centre

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