Surface Enhanced Raman Scattering (SERS)

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Background

Research focuses on the manipulation and measurement of molecules in the nanoscale. This involves the measurement of biological interactions, mainly using functionalised nanoparticles for applications in areas such as biosensors, diagnostics and self-assembled nanostructures.

Technology

The main focus is on the use of the combination of nanoparticles, biomolecules and spectroscopy to build bionanosensors to solve complex biological problems. One of the main themes of research focuses on using surface enhanced Raman scattering (SERS) to create new approaches to bioanalysis for use in the life and clinical sciences. SERS is a spectroscopic technique that offers significant advantages in the life sciences over other established techniques such as fluorescence. One of the key advantages of SERS, as well as increased sensitivity, is the ability to analyse multiple analytes in one sample. This allows more information to be gained per analysis as well as giving information about complex systems that are intrinsically difficult to measure.

Key Benefits

  • Sensitivity—single molecules can be detected
  • Selectivity— provided by in house chemistry
  • Multiplexing capabilities—up to 10 different species can be identified in one experiment without separation.

Markets and Applications

  • Molecular diagnostics
  • Immunoassays
  • Detection of protein biomarkers for diagnosis
  • Glucose sensing
  • Drug screening
  • Stem cell differentiation
  • Drug delivery

Licensing and Development

Opportunities exist for exploitation based on an active patent portfolio (13) with potential for licensing and partnering in the areas listed above. Please request further details for specific opportunities. Contact rkes@strath.ac.uk for further information.