Strathclyde Institute of Pharmacy & Biomedical SciencesContinuing professional development
Introduction to methods used in vaccine studies
Strathclyde Institute of Pharmacy & Biomedical Sciences (SIPBS) is a leading centre for research, focused on new medicines, better medicines and better use of medicines. SIPBS was ranked first in the UK for Pharmacology & Pharmacy by the Complete University Guide, and delivers an accredited four year MPharm degree together with a range of accredited BSc and MSci degrees in the Biomedical Sciences. SIPBS also hosts the Centre for Continuous Manufacturing and Crystallisation (CMAC), a world-class pharmaceutical manufacturing and innovation hub.
This course is delivered over two weeks. The first week is a refresher course on immunity to infection, methods used in phenotyping host immune responses, and statistical analysis of immunological data. The laboratory sessions will use integrated case studies as immunity involve multiple components. The second week builds upon the first week and looks at the clinical importance of vaccine studies, vaccine formulation and manufacture. The course will be run by staff at the university of Strathclyde and external speakers from other institutions and companies.
Student numbers: Places on this course are limited since the course is hands on and involve heavy practical load; therefore, early registration is essential.
Course schedule and outline: The indicative programme is provided below.
Welcome and introductions. Introduction to host immune responses, typing humoral immune responses
Introductory to integrated practical case study, use of ELISAs in isotyping immune responses lab A.
Cell mediated immunity and pathogen killing mechanisms.
Lymphocyte proliferation lab.
Immune cells phenotyping studies and importance of controls in flow cytometry.
Determination of CD3+, CD4+ and CD8+ immune cells in samples using flow cytometry lab
Role vaccines have played in controlling disease, adverse effects induced by vaccine formulations.
Measuring inflammatory mediators lab.
Data analysis workshop (part 1) and data interpretation studies
Presentation and statistical analysis of lab. data (part 1)
Role of route of administration and formulation on the efficacy of vaccine formulations. Introductory to integrated practical case study
In vivo vaccination methods lab and use of ELISAs in isotyping immune responses lab B.
Recent advances in the development of vaccines for bacterial and parasitic diseases
Use of IVIS imaging in determining local inflammatory responses and therapeutic outcome lab.
What does GMP manufacture of vaccines involve: using a veterinary and human vaccine example.
Use of flow cytometry in determining cytokine responses: multiplexing lab.
Role of vaccine hesitancy in vaccine programmes. Introduction to RT-PCR in vaccine studies.
Use of RT-PCR in determining multiple cytokine responses lab.
Data analysis workshop (part 2)
The course will last for two weeks, and the cost per student will be £5,000 including all consumables and necessary laboratory equipment.
Waiting List Courses will be scheduled on demand. To register on the waiting list contact Debbie Stack.