Professor Damion Corrigan

Pure and Applied Chemistry

Personal statement

Based on core expertise in electrochemical sensing, analytical chemistry and device fabrication my research aims to develop improved diagnostic tests for clinically important conditions such as, drug resistant bacterial infections, COVID-19, sepsis, cancer and epilepsy.  In the group we work on a range of sensor systems, from high value microfabricated arrays, to wearables and through to low cost devices for use in resource limited settings.

I am the LGC Professor in Measurement Science for Health and lead the Centre for Advanced Measurement and Health Translation - a joint initiative with the National Measurement Laboratory (NML) at the Laboratory of the Government Chemist (LGC) and the University of Stathclyde. The aim of the centre is to develop cutting edge interdisciplinary projects which drive new healthcare and measurement science R&D in Scotland.

In addition to academic research, translational activity is an important aspect of the group's work because we are keen to ensure that developments from the lab ultimately find real world application.  As a result of this, I am co-founder of two spin-out companies (Aureum Diagnostics and Microplate Dx) and am centrally involved in their onging R&D activity.

I joined Strathclyde in 2016 as a Chancellor's Fellow in Health Technologies, becoming a Senior Lecturer in the Department of Biomedical Engineering during 2019, Reader in 2021 and moving to the Department of Pure and Applied Chemistry in 2022 to become LGC Chair in Measurement Science for Health.  I have a background in biological and chemical sensing having obtained a PhD in Bioanalytical Chemistry from Cranfield University followed by periods of Post-Doctoral research at Southampton and Edinburgh Universities.  Past achievements include development of an assay for MRSA which was patented and licensed for further development, the award of a Longitude Prize Discovery Award during 2017 for a project called "Microplate" and with colleagues from the University of Leeds, development of a microelectrode sensor for prompt diagnosis of hyper inflammation.

My work is often highly interdisciplinary involving industrial partners (e.g. GSK, National Nuclear Laboratory, AstraZeneca, Lifescan, Aptamer Group, Flexmedical Solutions, Biotangents and other SMEs) and projects rely on close collaboration with other academics, including: clinicians, microbiologists, neuroscientists, electrical engineers and chemists. 

Areas of particular interest include: electrochemical and optical techniques, electrochemical impedance spectroscopy (EIS), microfabricated sensor systems and microelecrode sensor arrays for multi target diagnostic assays. I also have expertise of electrochemical sensing in harsh and extreme environments and aqueous & non aqueous electroplating.  Prior to joining Strathclyde, I was involved in developing a microelectrode sensor for use in nuclear fuel reprocessing (as part of the EPSRC sponsored "REFINE" project) and played a role in designing and comissioning an open access national facility for nuclear fuel reprocessing research at the University of Edinburgh.

Publications

Combining hyperspectral imaging and electrochemical sensing for detection of Pseudomonas aeruginosa through pyocyanin production
Dunphy R David, Lasserre Perrine, Riordan Lily, Duncan Katherine R R, McCormick Christopher, Murray Paul, Corrigan Damion
Sensors and Diagnostics (2022)
https://doi.org/10.1039/D2SD00044J
A fully integrated rapid on-chip antibiotic susceptibility test - a case study for Mycobacterium smegmatis
Gorbanpoor Hahmad, Norouz Dizaji Araz, Akcakoca Iremnur, Blair Ewen O, Ozturk Yasin, Hoskisson Paul, Kocagoz Tanil, Avci Huseyin, Corrigan Damion K, Guzel Fatma Dogan
Sensors and Actuators A: Physical Vol 339 (2022)
https://doi.org/10.1016/j.sna.2022.113515
Electrochemical antibiotic susceptibility testing – an emerging approach for fast and accurate determination of antibiotic effect in complex samples
Hannah Stuart, Domingo-Roca Roger, Hoskisson Paul A, Murphy Michael E, Corrigan Damion K
Current Opinion in Electrochemistry Vol 35 (2022)
https://doi.org/10.1016/j.coelec.2022.101033
An electrochemical biosensor with integrated microheater to improve the sensitivity of electrochemical nucleic acid biosensors
Akçakoca İremnur, Gorbanpoor Hahmad, Blair Ewen, Öztürk Yasin, Norouz Dizaji Araz, Kocagoz Tanil, Avci Huseyin, Corrigan Damion, Dogan Guzel Fatma
Journal of Micromechanics and Microengineering Vol 32, pp. 1-16 (2022)
https://doi.org/10.1088/1361-6439/ac5a62
Effect of microchannel dimensions in electrochemical impedance spectroscopy using gold microelectrode
Ghorbanpoor Hamed, Corrigan Damion, Guzel Fatma Doğan
Sakarya University Journal of Science Vol 26, pp. 119-126 (2022)
https://doi.org/10.16984/saufenbilder.982707
SARS-CoV-2 aptasensor based on electrochemical impedance spectroscopy and low-cost gold electrode substrates
Lasserre Perrine, Balansethupathy Banushan, Vezza Vincent J, Butterworth Adrian, Macdonald Alexander, Blair Ewen O, McAteer Liam, Hannah Stuart, Ward Andrew C, Hoskisson Paul A, Longmuir Alistair, Setford Steven, Farmer Eoghan C W, Murphy Michael E, Flynn Harriet, Corrigan Damion K
Analytical Chemistry Vol 94, pp. 2126–2133 (2022)
https://doi.org/10.1021/acs.analchem.1c04456

More publications

Teaching

I have a varied teaching history having led and delivered modules in the areas of: Cell Biology, Biophysical Chemistry, Biotechniques, Analytical Chemistry and Medical Ddiagnostics.

Professional activities

Development of biosensors for infectious disease
Speaker
3/11/2020
Development of diagnostic technologies for infectious and non-infectious diseases
Speaker
12/3/2020
Biologically modified electrodes for medical sensing applications
Speaker
3/2/2020
Development of electrochemical biosensors for the detection of sepsis and improved antimicrobial susceptibility testing.
Speaker
6/11/2019
Addressing the global rise in antimicrobial resistant infections through lab-on-a-chip technology
Participant
11/2019
Analytical Chemistry (Journal)
Peer reviewer
10/2019

More professional activities

Projects

Doctoral Training Partnership 2020-2021 University of Strathclyde | Milne, Stuart
Corrigan, Damion (Principal Investigator) Giardini, Mario Ettore (Co-investigator) Milne, Stuart (Research Co-investigator)
01-Jan-2021 - 01-Jan-2024
SenseCycle: point-of-care sensors for monitoring women's reproductive health
Jimenez, Melanie (Principal Investigator) Corrigan, Damion (Co-investigator)
01-Jan-2021 - 30-Jan-2023
Fluorous-based diagnostic platform for multiplexed diagnosis and differentiation of viral infections
Burley, Glenn (Principal Investigator) Corrigan, Damion (Co-investigator) Hoskisson, Paul (Co-investigator)
01-Jan-2021 - 31-Jan-2022
Microplate Dx High Growth Spinout Programme Phase 1I
Corrigan, Damion (Principal Investigator) Hoskisson, Paul (Co-investigator)
Funder - Scottish Enterprise
Value - £199,500.00
01-Jan-2021 - 31-Jan-2022
KTP - Biotangents
Corrigan, Damion (Principal Investigator) Ward, Andrew (Co-investigator)
01-Jan-2020 - 30-Jan-2022
Innovate UK ICURe Programme Phase 2
Hannah, Stuart (Co-investigator) Corrigan, Damion (Principal Investigator)
£15,000
10-Jan-2020 - 12-Jan-2021

More projects

Address

Pure and Applied Chemistry
Thomas Graham Building

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