Dr Stuart Hannah

Knowledge Exchange Fellow

Biomedical Engineering

Personal statement

My research is interested in the development of diagnostic tests for a range of important conditions such as antimicrobial resistance, cancerous biomarkers, infectious diseases within livestock farming, and detection of clinically important molecules including dopamine and ascorbic acid. I develop novel, low-cost electrode systems, suitable for use at the point of care. These systems typically exploit electrochemical techniques for the rapid detection of either biomarkers, specific molecules or bacterial growth.

Current projects I am involved with include development of a rapid, antibiotic susceptibility test, a low-cost sensor for the detection of clinically important neurotransmitter dopamine, optimisation of a process for detection of infectious diseases within the agricultural sector.

I have experience in the supervision of final year undergraduate students and postgraduate level students.

I joined the department of Biomedical Engineering at Strathclyde in 2018 having previously studied for both my undergraduate degree and PhD degree in Electronic and Electrical Engineering at Strathclyde. My PhD involved the development of force and temperature sensors based on organic field-effect transistors and ferroelectric materials. During my PhD, I optimised the transistor dielectric layer to provide transistors with low-voltage operation, and transferred a fully vacuum evaporated transistor fabrication process onto flexible plastic foils. I also developed force/temperature sensors using ferroelectric material P(VDF-TrFE), and incorporated these sensors with organic transistors to provide signal amplification and a useful readout signal for applications ranging from touch screen interfaces to electronic skin. Following my PhD, I worked as a postdoctoral researcher at Ecole des Mines de Saint-Etienne, Gardanne, France for 14 months working on stretchable electronics for biosensing applications. During this time, I developed a conformable, stretchable sensor to record bladder wall stretch to aid treatment of conditions such as urinary urge incontinence and overactive bladder syndrome.

My work is highly interdisciplinary involving industrial partners, clinicians, and working alongside other academics such as microbiologists, chemists and electronics engineers.  


SARS-CoV-2 aptasensor based on electrochemical impedance spectroscopy and low-cost gold electrode substrates
Lasserre Perrine, Balansethupathy Banushan, Vezza Vincent J, Butterworth Adrian, Macdonald Alexander, Blair Ewen O, McAteer Liam, Hannah Stuart, Ward Andrew C, Hoskisson Paul A, Longmuir Alistair, Setford Steven, Farmer Eoghan C W, Murphy Michael E, Flynn Harriet, Corrigan Damion K
Analytical Chemistry Vol 94, pp. 2126–2133 (2022)
An electrochemical SARS-CoV-2 biosensor inspired by glucose test strip manufacturing processes
Vezza Vincent J, Butterworth Adrian, Lasserre Perrine, Blair Ewen O, MacDonald Alexander, Hannah Stuart, Rinaldi Christopher, Hoskisson Paul A, Ward Andrew C, Longmuir Alistair, Setford Steven, Farmer Eoghan C W, Murphy Michael E, Corrigan Damion K
Chemical Communications Vol 57, pp. 3704-3707 (2021)
Biologically modified microelectrode sensors provide enhanced sensitivity for detection of nucleic acid sequences from Mycobacterium tuberculosis
Blair Ewen O, Hannah Stuart, Vezza Vincent, Avci Hüseyin, Kocagoz Tanil, Hoskisson Paul A, Güzel Fatma D, Corrigan Damion K
Sensors and Actuators Reports Vol 2 (2020)
Developments in microscale and nanoscale sensors for biomedical sensing
Hannah Stuart, Blair Ewen, Corrigan Damion K
Current Opinion in Electrochemistry Vol 23, pp. 7-15 (2020)
Development of a rapid, antimicrobial susceptibility test for E. coli based on low-cost, screen-printed electrodes
Hannah Stuart, Dobrea Alexandra, Lasserre Perrine, Blair Ewen O, Alcorn David, Hoskisson Paul A, Corrigan Damion K
Biosensors Vol 10 (2020)
Low-cost, thin-film, mass-manufacturable carbon electrodes for detection of the neurotransmitter dopamine
Hannah Stuart, Al-Hatmi Maha, Gray Louise, Corrigan Damion K
Bioelectrochemistry Vol 133 (2020)

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In terms of teaching, I contribute to the following undergraduate and masters courses in the department of Biomedical Engineering –

BE428 – Professional Studies and Research Methods in Biomedical Engineering

BE207 – Human Cell Biology 2

Professional activities

Engage with Strathclyde
Oral Presentation at RSC ABG ECRM 2020 in Glasgow
Converge Challenge Finalist
STV News Interview on Microplate Project
Radio Scotland Interview on Microplate Project
2019 Scotland and North of England Electrochemistry Symposium (Butler Meeting)

More professional activities


Exploration of medicines waste management services in the United Kingdom
GANGANNAGARIPALLI, Jaheedabegum (Principal Investigator) Mueller, Tanja (Principal Investigator) Hannah, Stuart (Principal Investigator) Horgan, Donagh (Principal Investigator) McLaughlin, Graeme (Principal Investigator) Simmons, Emilee Lauran (Principal Investigator)
Although being at the core of patients’ treatment, an estimated £300m of NHS prescribed medicines are wasted annually, and medicines are increasingly being considered as emerging environmental hazards due to inappropriate management and pollution associated with their use. Medicines management is a complex issue, defined as “the entire way medicines are selected, procured, delivered, prescribed, administered, and reviewed to optimise the contribution that medicines make to producing informed and desired outcomes of patient care”. Hence, it is imperative to develop broad and wide-ranging medicines management methods to reduce waste and prevent environmental pollution, enable sustainability, improve patients’ health and wellbeing, and reduce cost. However, there is currently limited research in this area.
The principal aim of this study is to perform a pilot exploration of effective waste management methods and/or services in order to understand the drivers of wastage in medicines management processes, and to identify touchpoints in the service to be redesigned, within the UK.
01-Jan-2021 - 30-Jan-2022
Microplate Dx (RSE Enterprise Fellowship - Stuart Hannah)
Hannah, Stuart (Principal Investigator)
01-Jan-2021 - 30-Jan-2022
Innovate UK ICURe Programme Phase 2
Hannah, Stuart (Co-investigator) Corrigan, Damion (Principal Investigator)
10-Jan-2020 - 12-Jan-2021
Innovate UK ICURe Phase 1
Hannah, Stuart (Co-investigator) Corrigan, Damion (Principal Investigator)
14-Jan-2020 - 10-Jan-2020
ICURe - Microplate
Corrigan, Damion (Principal Investigator) Hannah, Stuart (Research Co-investigator)
14-Jan-2020 - 14-Jan-2020
Improving rational drug prescription: a rapid and low-cost antibiotic susceptibility test for drug resistant/susceptible tuberculosis
Blair, Ewen (Co-investigator) Corrigan, Damion (Principal Investigator) Hannah, Stuart (Co-investigator)
Multidrug resistant TB (MDR-TB) is a significant healthcare challenge. For example, in 2016 there were 558,000 new cases globally. Quoting the World Health Organisation “Multidrug-resistant TB (MDR-TB) is multifactorial and fuelled by improper treatment of patients, poor management of supply and quality of drugs, and airborne transmission of bacteria in public places. Case management becomes difficult and the challenge is compounded by catastrophic economic and social costs that patients incur while seeking help and on treatment”.
A vital aspect of mitigating the health, social and economic costs associated with MDR-TB is the ability to rapidly diagnose the disease and quickly pinpoint which antibiotics will be effective.
DC’s group have been developing a new rapid antibiotic susceptibility test called “Microplate”. This technology was acknowledged with a prestigious Longitude Prize Discovery Award during 2017. We have recently published our first demonstration of the Microplate approach to drug susceptibility testing (with MRSA) and now have the opportunity through this pump-priming scheme to collaborate with groups in India to develop the technology specifically for MDR-TB. The technology is easy to use, low cost, mass manufacturable and fits well with established microbiological methods. It is therefore ideal for deployment in low resource settings.
01-Jan-2020 - 30-Jan-2020

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