My research is interested in the development of diagnostic tests for a range of important conditions such as antimicrobial resistance, cancerous biomarkers, infectious diseases within livestock farming, and detection of clinically important molecules including dopamine and ascorbic acid. I develop novel, low-cost electrode systems, suitable for use at the point of care. These systems typically exploit electrochemical techniques for the rapid detection of either biomarkers, specific molecules or bacterial growth.
Current projects I am involved with include development of a rapid, antibiotic susceptibility test, a low-cost sensor for the detection of clinically important neurotransmitter dopamine, optimisation of a process for detection of infectious diseases within the agricultural sector.
I have experience in the supervision of final year undergraduate students and postgraduate level students.
I joined the department of Biomedical Engineering at Strathclyde in 2018 having previously studied for both my undergraduate degree and PhD degree in Electronic and Electrical Engineering at Strathclyde. My PhD involved the development of force and temperature sensors based on organic field-effect transistors and ferroelectric materials. During my PhD, I optimised the transistor dielectric layer to provide transistors with low-voltage operation, and transferred a fully vacuum evaporated transistor fabrication process onto flexible plastic foils. I also developed force/temperature sensors using ferroelectric material P(VDF-TrFE), and incorporated these sensors with organic transistors to provide signal amplification and a useful readout signal for applications ranging from touch screen interfaces to electronic skin. Following my PhD, I worked as a postdoctoral researcher at Ecole des Mines de Saint-Etienne, Gardanne, France for 14 months working on stretchable electronics for biosensing applications. During this time, I developed a conformable, stretchable sensor to record bladder wall stretch to aid treatment of conditions such as urinary urge incontinence and overactive bladder syndrome.
My work is highly interdisciplinary involving industrial partners, clinicians, and working alongside other academics such as microbiologists, chemists and electronics engineers.
In terms of teaching, I contribute to the following undergraduate and masters courses in the department of Biomedical Engineering –
BE428 – Professional Studies and Research Methods in Biomedical Engineering
BE207 – Human Cell Biology 2
- Oral Presentation at RSC ABG ECRM 2020 in Glasgow
- STV News Interview on Microplate Project
- Radio Scotland Interview on Microplate Project
- 2019 Scotland and North of England Electrochemistry Symposium (Butler Meeting)
- Fabrication and development of electrode systems for label-free biosensing
- Force and Temperature Sensors Based on Organic Thin-Film Transistors and P(VDF-TrFE)
More professional activities
- Microplate Dx (RSE Enterprise Fellowship - Stuart Hannah)
- Hannah, Stuart (Principal Investigator)
- 01-Jan-2021 - 30-Jan-2022
- ICURe - Microplate
- Corrigan, Damion (Principal Investigator) Hannah, Stuart (Research Co-investigator)
- 14-Jan-2020 - 14-Jan-2020
- Improving rational drug prescription: a rapid and low-cost antibiotic susceptibility test for drug resistant/susceptible tuberculosis
- Blair, Ewen (Co-investigator) Corrigan, Damion (Principal Investigator) Hannah, Stuart (Co-investigator)
- Multidrug resistant TB (MDR-TB) is a significant healthcare challenge. For example, in 2016 there were 558,000 new cases globally. Quoting the World Health Organisation “Multidrug-resistant TB (MDR-TB) is multifactorial and fuelled by improper treatment of patients, poor management of supply and quality of drugs, and airborne transmission of bacteria in public places. Case management becomes difficult and the challenge is compounded by catastrophic economic and social costs that patients incur while seeking help and on treatment”.
A vital aspect of mitigating the health, social and economic costs associated with MDR-TB is the ability to rapidly diagnose the disease and quickly pinpoint which antibiotics will be effective.
DC’s group have been developing a new rapid antibiotic susceptibility test called “Microplate”. This technology was acknowledged with a prestigious Longitude Prize Discovery Award during 2017. We have recently published our first demonstration of the Microplate approach to drug susceptibility testing (with MRSA) and now have the opportunity through this pump-priming scheme to collaborate with groups in India to develop the technology specifically for MDR-TB. The technology is easy to use, low cost, mass manufacturable and fits well with established microbiological methods. It is therefore ideal for deployment in low resource settings.
- 01-Jan-2020 - 30-Jan-2020
- PhD Project - Extended research exchange on electrochemical biosensors
- Corrigan, Damion (Principal Investigator) Hannah, Stuart (Co-investigator) Schulte, Albert (Co-investigator) Thaweskulchai, Thana (Post Grad Student)
- 01-Jan-2019 - 01-Jan-2020
- Carnegie Trust - sponsored summer internship - Lisa Crossley
- Corrigan, Damion (Principal Investigator) Hannah, Stuart (Co-investigator)
- 17-Jan-2019 - 31-Jan-2019
- CENSIS Project with Biotangents Ltd
- Corrigan, Damion (Principal Investigator) Hannah, Stuart (Researcher)
- 18-Jan-2019 - 18-Jan-2019
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