Personal statement
Neil is a Reader working in the Biomolecular and Chemical Physics group, part of the Nanoscience division. Research in Neil’s Multidimensional Spectroscopy Group concentrates on applying ultrafast two dimensional infrared (2D-IR) spectroscopy to the study of biological systems. Recently, he obtained a high profile ERC Starting Investigator Grant to extend this technique to allow the observation of real-time changes in molecular structure during reactions. Neil also collaborates closely with the Central Laser Facility at the STFC Rutherford Appleton Laboratory on developing 2D-IR and transient 2D-IR methods for studying biological systems.
Professional activities
- Austin Symposium on Molecular Structure and Dynamics, Dallas, USA,
- Invited speaker
- 1/3/2016
- Pacifichem Congress, Honolulu, Hawaii, USA
- Invited speaker
- 17/12/2015
- DfG Roundtable Meeting on Photoreceptors, Munich, Germany
- Invited speaker
- 10/10/2015
- Advances in Structure and Dynamics, Bangalore, India
- Invited speaker
- 6/1/2015
- Laserlab Europe, Lasers for Life Meeting, London
- Invited speaker
- 15/6/2014
- CCP9 Workshop "Electronic excitations and dynamics in macromolecules and extended systems"
- Invited speaker
- 28/9/2013
more professional activities
Projects
- Doctoral Training Partnership (DTP 2016-2017 University of Strathclyde) | Hume, Samantha
- Hunt, Neil (Principal Investigator) Baker, Matthew (Co-investigator) Hume, Samantha (Research Co-investigator)
- Period 01-Oct-2016 - 01-Apr-2020
- Doctoral Training Grant 2006 | Craigon, Alison
- Hunt, Neil (Principal Investigator) Hourahine, Benjamin (Co-investigator) Craigon, Alison (Research Co-investigator)
- Period 01-Oct-2006 - 27-Oct-2016
- BBSRC Doctoral Training Grant (DTG) | Bellota-Anton, Cesar
- Tucker, Nicholas (Principal Investigator) Hunt, Neil (Co-investigator) Bellota-Anton, Cesar (Research Co-investigator)
- Period 01-Dec-2011 - 01-Dec-2014
- BBSRC Doctoral Training Grant (DTG) | Robb, Kirsty
- Hoskisson, Paul (Principal Investigator) Hunt, Neil (Co-investigator) Robb, Kirsty (Research Co-investigator)
- Period 01-Oct-2011 - 16-Feb-2016
- EPSRC Doctoral Training Grant - DTA, University of Strathclyde | Ramakers, Lennart
- Hunt, Neil (Principal Investigator) Burley, Glenn (Co-investigator) Ramakers, Lennart (Research Co-investigator)
- The binding of proteins and small molecules to double-stranded (ds)-DNA is fundamental to biological function, but our comprehension of the underlying molecular physics of these interactions remains incomplete. Here, we focus on minor groove binding compounds (MGBs). These are small organic molecules that demonstrate sequence specificity favouring AT-rich tracts of dsDNA and which have potential applications as next-generation antibiotics. We utilize two dimensional infrared spectroscopy (2D-IR) to investigate MGB-DNA complexes that allow us to explore the interactions and dynamics of binding by exploiting azide-containing molecular probes based on the Hoechst DNA-binding dye family with the aim of providing bond-level spatial resolution within the minor groove on timescales approaching 100 fs. By characterizing the response of archetypical small organic molecules containing an azide moiety to their local environment and using this information with the insights gained by studying the vibrations of the DNA bases, these interactions can be explored.
- Period 01-Oct-2013 - 01-Apr-2017
- EPSRC Doctoral Training Grant - DTA, University of Strathclyde | Hithell, Gordon Robert
- Hunt, Neil (Principal Investigator) Burley, Glenn (Co-investigator) Hithell, Gordon Robert (Research Co-investigator)
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- Period 01-Oct-2013 - 01-Apr-2017
more projects
Address
Physics
John Anderson Building
John Anderson Building
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