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Prof Neil Hunt

Physics

Personal statement

Neil is a Reader working in the Biomolecular and Chemical Physics group, part of the Nanoscience division. Research in Neil’s Multidimensional Spectroscopy Group concentrates on applying ultrafast two dimensional infrared (2D-IR) spectroscopy to the study of biological systems. Recently, he obtained a high profile ERC Starting Investigator Grant to extend this technique to allow the observation of real-time changes in molecular structure during reactions.  Neil also collaborates closely with the Central Laser Facility at the STFC Rutherford Appleton Laboratory on developing 2D-IR and transient 2D-IR methods for studying biological systems.

Publications

Examining the role of protein structural dynamics in drug resistance in Mycobacterium tuberculosis
Shaw Daniel J., Hill Rachel E., Simpson Niall, Husseini Fouad S., Robb Kirsty, Greetham Gregory M., Towrie Michael, Parker Anthony W., Robinson David , Hirst Jonathan D. , Hoskisson Paul, Hunt Neil T.
Chemical Science, (2017)
http://dx.doi.org/10.1039/C7SC03336B
Quantifying secondary structure changes in Calmodulin using 2D-IR spectroscopy
Minnes Lucy, Shaw Daniel J., Cossins Benjamin P., Donaldson Paul M., Greetham Gregory M., Towrie Michael, Parker Anthony W., Baker Matthew J., Henry Alistair J., Taylor Richard J., Hunt Neil T.
Analytical Chemistry, (2017)
http://dx.doi.org/10.1021/acs.analchem.7b02610
Disruption of key NADH-binding pocket residues of the Mycobacterium tuberculosis InhA affects DD-CoA binding ability
Shaw Daniel J., Robb Kirsty, Vetter Beatrice V., Tong Madeline, Molle Virginie, Hunt Neil T., Hoskisson Paul A.
Scientific Reports Vol 7, (2017)
http://dx.doi.org/10.1038/s41598-017-05042-4
Ultrafast 2D-IR and optical Kerr effect spectroscopy reveal the impact of duplex melting on the structural dynamics of DNA
Hithell Gordon, González-Jiménez Mario, Greetham Gregory M., Donaldson Paul M., Towrie Michael, Parker Anthony W., Burley Glenn A., Wynne Klaas, Hunt Neil
Physical Chemistry Chemical Physics, (2017)
2D-IR spectroscopy shows that optimised DNA minor groove binding of Hoechst33258 follows an induced fit model
Ramakers Lennart A. I., Hithell Gordon, May John J., Greetham Gregory M., Donaldson Paul M., Towrie Michael, Parker Anthony W., Burley Glenn, Hunt Neil
Journal of Physical Chemistry B, (2017)
http://dx.doi.org/10.1021/acs.jpcb.7b00345
Tunable supramolecular hydrogels for selection of lineage-guiding metabolites in stem cell cultures
Alakpa Enateri V., Jayawarna Vineetha, Lampel Ayala, Burgess Karl V., West Christopher C., Bakker Sanne C.J., Roy Sangita, Javid Nadeem, Fleming Scott, Lamprou Dimitris A., Yang Jingli, Miller Angela, Urquhart Andrew J., Frederix Pim W.J.M., Hunt Neil T., Péault Bruno, Ulijn Rein V., Dalby Matthew J.
Chem Vol 1, pp. 298-319, (2016)
http://dx.doi.org/10.1016/j.chempr.2016.07.001

more publications

Professional activities

Austin Symposium on Molecular Structure and Dynamics, Dallas, USA,
Invited speaker
1/3/2016
Pacifichem Congress, Honolulu, Hawaii, USA
Invited speaker
17/12/2015
DfG Roundtable Meeting on Photoreceptors, Munich, Germany
Invited speaker
10/10/2015
Advances in Structure and Dynamics, Bangalore, India
Invited speaker
6/1/2015
Laserlab Europe, Lasers for Life Meeting, London
Invited speaker
15/6/2014
CCP9 Workshop "Electronic excitations and dynamics in macromolecules and extended systems"
Invited speaker
28/9/2013

more professional activities

Projects

Fast-tracking Health Innovation for NHS Scotland (MRC Confidence in Concept 2017) / R170262-101
Baker, Matthew (Principal Investigator) Hunt, Neil (Co-investigator)
Period 01-Mar-2017 - 28-Feb-2019
Impact Acceleration Account - University Of Strathclyde 2012 / R120526-217
Hunt, Neil (Principal Investigator)
Period 01-Oct-2012 - 31-Mar-2017
Doctoral Training Partnership (DTP 2016-2017 University of Strathclyde) | Hume, Samantha
Hunt, Neil (Principal Investigator) Baker, Matthew (Co-investigator) Hume, Samantha (Research Co-investigator)
Period 01-Oct-2016 - 01-Apr-2020
Doctoral Training Grant 2006 | Craigon, Alison
Hunt, Neil (Principal Investigator) Hourahine, Benjamin (Co-investigator) Craigon, Alison (Research Co-investigator)
Period 01-Oct-2006 - 27-Oct-2016
BBSRC Doctoral Training Grant (DTG) | Bellota-Anton, Cesar
Tucker, Nicholas (Principal Investigator) Hunt, Neil (Co-investigator) Bellota-Anton, Cesar (Research Co-investigator)
Period 01-Dec-2011 - 01-Dec-2014
BBSRC Doctoral Training Grant (DTG) | Robb, Kirsty
Hoskisson, Paul (Principal Investigator) Hunt, Neil (Co-investigator) Robb, Kirsty (Research Co-investigator)
Period 01-Oct-2011 - 16-Feb-2016

more projects