Dr Vania Moreira

Strathclyde Chancellor's Fellow

Strathclyde Institute of Pharmacy and Biomedical Sciences

Personal statement

 

ORCID: 0000-0001-6169-5035

 

CURRENT POSITIONS

** University Lecturer

Strathclyde Institute of Pharmacy and Biomedical Sciences, University of Strathclyde, United Kingdom

 

**Adjunct Professor (Dos.)

Drug Discovery Programme, Faculty of Pharmacy, University of Helsinki, Finland

 

EDUCATION AND DEGREES AWARDED

**Fellow of the Higher Education Academy, UK (FHEA), 2018

**Title of “Dosentti” (Adjunct Professor) in Pharmaceutical Chemistry, University of Helsinki, Finland, 2015

**Ph.D. in Pharmaceutical Organic Chemistry, University of Coimbra, Portugal & University of Maryland, USA, (highest-scoring grade, “Passed with Distinction and Honours”), 2008

**Degree in Pharmaceutical Sciences (Pharm.D.), University of Coimbra, Portugal, Grade 17 out of 20 (First-class honours), awarded with the “ Sociedade Farmacêutica Lusitana Award” (best student of Pharmaceutical Sciences of the year in Portugal), 2003

 

RESEARCH AREAS

Drug Discovery, Medicinal Chemistry, Natural Products, Antimicrobial and anti-biofilm agents & materials, Neglected diseases, Cancer, (Neuro)inflammation

 

MAJOR FUNDING SOURCES

The Finnish Funding Agency for Innovation (TEKES); Huonekalusäätio; University of Helsinki Research Funds; Magnus Ehrnrooth Foundation; Portuguese Science and Technology Foundation (FCT); FP7-HEALTH-2013-INNOVATION-1 (European Funding); Academy of Finland; Tenovus Sctoland

 

CURRENT COMPOSITION OF RESEARCH GROUP

Doctoral students

Declan Mullen (Oct 2018 - ); Next generation bio-based antimicrobial agents

Ghada Hassan (Sep 2016-); Sustainable antimicrobial coatings

Tiina Ahonen (Sep 2014-); New drugs for chronic pain

Nina Forsman (co-supervisor; Sep 2016-); Sustainable multifunctional coatings for textiles and other cellulosic materials

 

FORMER RESEARCH GROUP MEMBERS

Post-doctoral researchers

Dr. Xing Wan (May 2017- Jan 2018); Sustainable antimicrobial coatings

Dr. Leena Keurulainen (Sep 2016 - Apr 2017); Sustainable antimicrobial coatings

Doctoral students

Dr. Laura Kolsi (graduated 2019); Synthesis of Abietane-Type Diterpenoids with Anticancer Activity

Dr. Raisa Haavikko (graduated 2015); Synthesis of betulins with new bioactivities

Dr. Nehad El-Salamouni (graduated 2013); Design and synthesis of some novel phenolic compounds and their quinone oxidation products of potential biological activities

 

Publications

Pyrazine-fused triterpenoids block the TRPA1 ion channel in vitro and inhibit TRPA1-mediated acute inflammation in vivo
Mäki-Opas Ilari, Hämäläinen Mari, Moilainen Lauri J, Haavikko Raisa, Ahonen Tiina J, Alakurtti Sami, Moreira Vânia M, Muraki Katsuhiko, Yli-Kauhaluoma Jari, Moilainen Eeva
ACS Chemical Neuroscience Vol 10, pp. 2848-2857 (2019)
https://doi.org/10.1021/acschemneuro.9b00083
Dehydroabietylamine-based cellulose nanofibril films : a new class of sustainable biomaterials for highly efficient, broad-spectrum antimicrobial effects
Hassan Ghada, Forsman Nina, Wan Xing, Keurulainen Leena, Bimbo Luis M, Johansson Leena-Sisko, Sipari Nina, Yli-Kauhaluoma Jari, Zimmernann Ralf, Stehl Susanne, Werner Carsten, Saris Per E J, Osterberg Monika, Moreira Vania M
ACS Sustainable Chemistry and Engineering Vol 7, pp. 5002-5009 (2019)
https://doi.org/10.1021/acssuschemeng.8b05658
Discovery of 12-thiazole abietanes as selective inhibitors of the human metabolic serine hydrolase hABHD16A
Ahonen Tiina J, Savinainen Juha R, Yli-Kauhaluoma Jari, Kalso Eija, Laitinen Jarmo T, Moreira Vânia M
ACS Medicinal Chemistry Letters Vol 9, pp. 1269-1273 (2018)
https://doi.org/10.1021/acsmedchemlett.8b00442
Dehydroabietic oximes halt pancreatic cancer cell growth in the G1 phase through induction of p27 and downregulation of cyclin D1
Kolsi Laura E, Leal Ana S, Yli-Kauhaluoma Jari, Liby Karen T, Moreira Vania M
Scientific Reports Vol 8 (2018)
https://doi.org/10.1038/s41598-018-34131-1
Catalytic, tunable, one-step bismuth(III) triflate reaction with alcohols : dehydration vs dimerization
Kolsi Laura E, Yli-Kauhaluoma Jari, Moreira Vania M
ACS Omega Vol 3, pp. 8836–8842 (2018)
https://doi.org/10.1021/acsomega.8b01401
Synthesis of 7β-hydroxy-8-ketone opioid derivatives with antagonist activity at the mu- and delta- opioid receptors
Ahonen Tiina J, Rinne Maiju, Grutschreiber Peter, Mätlik Kert, Airavaara Mikko, Schaarschmidt Dieter, Lang Heinrich, Reiss David, Xhaard Henri, Gavériaux-Ruff Claire, Yli-Kauhaluoma Jari, Moreira Vânia M
European Journal of Medicinal Chemistry Vol 151, pp. 495-507 (2018)
https://doi.org/10.1016/j.ejmech.2018.02.074

more publications

Professional activities

Resin-acids driven innovations in antimicrobial research
Speaker
21/8/2019
University of Eastern Finland (External organisation)
Advisor
6/2019
"Day of Science - St Margaret's High School pupils
Recipient
9/5/2019
Day of Science @ Strathclyde - SIPBS: Cat Allergy Simulation and STEM activity stands
Contributor
9/5/2019
Internal examiner to doctoral thesis (Bela Sanches)
Examiner
3/2019
Agència de Qualitat i Avaluació Sanitàries de Catalunya (External organisation)
Advisor
2019

more professional activities

Projects

Diterpenoid-based scaffolds for enabling skin repair
Moreira, Vania (Principal Investigator)
01-Jan-2019 - 31-Jan-2020
Doctoral Training Partnership 2018-19 University of Strathclyde | Mullen, Declan
Moreira, Vania (Principal Investigator) Parkinson, John (Co-investigator) Mullen, Declan (Research Co-investigator)
01-Jan-2018 - 01-Jan-2021
Sustainable Hydrophobic Materials for Antimicrobial Coatings
Moreira, Vania (Principal Investigator)
01-Jan-2016 - 31-Jan-2018
Fully renewable bioactive textiles II
Moreira, Vania (Principal Investigator)
29-Jan-2015 - 31-Jan-2015
Fully renewable bioactive textiles
Moreira, Vania (Principal Investigator)
27-Jan-2014 - 27-Jan-2015
EC-FP7-HEALTH-2013-INNOVATION-1: Understanding chronic pain and new druggable targets: Focus on glial-opioid receptor interface (GLORIA)
Moreira, Vania (Research Co-investigator) Ruff-Gaveriaux, Claire (Co-investigator) Yli-Kauhaluoma, Jari Tapani (Co-investigator) Airavaara, Mikko (Co-investigator) Ahonen, Tiina (Post Grad Student) Xhaard, Henri (Co-investigator) Kalso, Eija (Principal Investigator) Saarma, Mart (Co-investigator)
01-Jan-2013 - 31-Jan-2018

more projects

Address

Strathclyde Institute of Pharmacy and Biomedical Sciences
Hamnett Wing

Location Map

View University of Strathclyde in a larger map