Dr Helen Elizabeth Mulvana

Chancellor'S Fellowships

Biomedical Engineering

Personal statement

My research focus is the development of advanced diagnostic tools for the earlier diagnosis and targeted treatment of cancer. I work closely with clinicians to better understand clinical needs and with engineers and life scientists to develop solutions to these challenges.

Current funding supports research projects on the development of elasticity imaging using contrast-enhanced magneto-motive ultrasound for the early detection of colorectal cancer, a pilot clinical trial to establish effectiveness of contrast enhanced ultrasound to detect sentinel lymph nodes in rectal cancer, development of physiological flow phantoms to investigate factors capable of influencing ultrasound and microbubble mediated drug delivery, delivery of siRNA using ultrasound and microbubbles to treat hypertension in a mouse model and investigation of low frequency ultrasound to stimulate bone repair. I also have expertise in non-linear acoustics, contrast imaging, microbubbles, medical device design and fabrication, therapeutic ultrasound and elastography.

Currently available PhD studentships:

I am always keen to hear from prospective PhD students and post doctoral researchers with complimentary research interests, please get in touch to discuss.

I am currently advertising a PDRA position to work on micro-vessel flow phantoms for ultrasound therapy research and a fully-funded Medical Research Scotland PhD studentship in collaboration with NPL Ltd to investigate tissue biomechanics at the microscale. Please contact me or search on findaphd.com and jobs.ac.uk for more details. 

Expertise

Has expertise in:

    Membership of Professional Bodies

    • Young Academy Scotland, Royal Society of Edinburgh (August 2018)
    • Institute of Physics MInstP (January 2015)
    • Higher Education Academy FHEA (December 2015)
    • Institution of Mechanical Engineers MIMechE (October 1997) CEng (January 2014)

    Current Committee Memberships

    • IEEE UFFC Publicity Chair & Web Editor in Chief (from 2020)
    • Associate Editor in Chief of IEEE T-UFFC (from 2020)
    • Publicity Chair, IEEE International Ultrasonics Symposium 2020
    • Co-Chair Legacy and Outreach, IEEE International Ultrasonics Symposium 2019
    • IEEE UFFC representative to TMI, member of AdCom (from 2019)
    • Associate Editor of IEEE T-UFFC (from 2017)
    • Physical Acoustics Group, Institute of Physics Committee (from 2015), Treasurer (from 2018).
    • IEEE Ultrasonics Symposium, Technical Program Committee (from 2014)
    • Scottish Ultrasound Group, Founder and Chair (June 2013)

Prizes and awards

VisNET Collaboration Event Social Dinner
Recipient
24/10/2019

more prizes and awards

Publications

From animal models to patients : the role of placental microRNAs, miR-210, miR-126, and miR-148a/152 in preeclampsia
Frazier Sonya, McBride Martin W, Mulvana Helen, Graham Delyth
Clinical Science Vol 134, pp. 1001-1025 (2020)
https://doi.org/10.1042/CS20200023
Ultrasound and microbubble gene delivery for targeting altered placental microRNAs in preeclampsia
Frazier Sonya, Morgan Hannah, McBride Martin, Bradshaw Angela, Mulvana Helen, Graham Delyth
2019 IEEE International Ultrasonics Symposium, IUS 2019 2019 IEEE International Ultrasonics Symposium IEEE International Ultrasonics Symposium, IUS Vol 2019-October, pp. 1551-1555 (2019)
https://doi.org/10.1109/ULTSYM.2019.8926052
Contrast-enhanced magnetomotive ultrasound imaging (CE-MMUS) for colorectal cancer staging : assessment of sensitivity and resolution to detect alterations in tissue stiffness
Sjöstrand Sandra, Evertsson Maria, Thring Claire, Bacou Marion, Farrington Susan, Moug Susan, Moran Carmel, Jansson Tomas, Mulvana Helen
2019 IEEE International Ultrasonics Symposium, IUS 2019 2019 IEEE International Ultrasonics Symposium IEEE International Ultrasonics Symposium, IUS Vol 2019-October, pp. 1077-1080 (2019)
https://doi.org/10.1109/ULTSYM.2019.8926058
Quantitative ultrasound differentiates brain and brain tumour phantoms
Thomson Hannah, Yang Shufan, Stritch Thomas, Baldwin Mitch, Mulvana Helen, Cochran Sandy
2019 IEEE International Ultrasonics Symposium, IUS 2019 2019 IEEE International Ultrasonics Symposium IEEE International Ultrasonics Symposium, IUS Vol 2019-October, pp. 2420-2423 (2019)
https://doi.org/10.1109/ULTSYM.2019.8925982
A controlled in vitro study of optimal low intensity pulsed ultrasound fields for stimulation of proliferation in murine osteoblasts
Savva Jill, Lucas Margaret, Mulvana Helen
2019 IEEE International Ultrasonics Symposium, IUS 2019 2019 IEEE International Ultrasonics Symposium IEEE International Ultrasonics Symposium, IUS Vol 2019-October, pp. 1543-1546 (2019)
https://doi.org/10.1109/ULTSYM.2019.8925594
Rapid prototyped microvessel flow phantom for controlled investigation of ultrasound-mediated targeted drug delivery
Domingo-Roca Roger, Saltin Brian, Windmill James, Jackson Joseph, Mulvana Helen
2019 IEEE International Ultrasonics Symposium, IUS 2019 2019 IEEE International Ultrasonics Symposium IEEE International Ultrasonics Symposium, IUS Vol 2019-October, pp. 2390-2393 (2019)
https://doi.org/10.1109/ULTSYM.2019.8925741

more publications

Projects

Transformative Anatomically accurate Microvascular flow Phantoms for Ultrasound therapy research (TAMP-US)
Mulvana, Helen Elizabeth (Principal Investigator) Jackson, Joseph (Co-investigator) O'Leary, Richard (Co-investigator) Sandison, Mairi (Co-investigator)
01-Jan-2020 - 31-Jan-2021
VisNET Collaboration Event Social Dinner
Mulvana, Helen Elizabeth (Principal Investigator) Aranceta Garza, Alejandra (Co-investigator) Zimbitas, Georgina (Co-investigator) Fabbri, Federica (Co-investigator) Keating, Ciara (Co-investigator) Echavarri Bravo, Virginia (Co-investigator)
International collaboration Dinner event funded by the Royal Society of Chemistry for a total value of £2,903.30
24-Jan-2019 - 25-Jan-2019

more projects

Address

Biomedical Engineering
Graham Hills Building

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