Dr Helen Elizabeth Mulvana

Chancellor'S Fellowships

Biomedical Engineering

Personal statement

My research focus is the development of advanced diagnostic tools for the earlier diagnosis and targeted treatment of cancer. I work closely with clinicians to better understand clinical needs and with engineers and life scientists to develop solutions to these challenges.

Current funding supports research projects on the development of elasticity imaging using contrast-enhanced magneto-motive ultrasound for the early detection of colorectal cancer, a pilot clinical trial to establish effectiveness of contrast enhanced ultrasound to detect sentinel lymph nodes in rectal cancer, development of physiological flow phantoms to investigate factors capable of influencing ultrasound and microbubble mediated drug delivery, delivery of siRNA using ultrasound and microbubbles to treat hypertension in a mouse model and investigation of low frequency ultrasound to stimulate bone repair. I also have expertise in non-linear acoustics, contrast imaging, microbubbles, medical device design and fabrication, therapeutic ultrasound and elastography.

Currently available PhD studentships:

I am always keen to hear from prospective PhD students and post doctoral researchers with complimentary research interests, please get in touch to discuss.

Publications

Traditional multiwell plates and petri dishes limit the evaluation of the effects of ultrasound on cells in vitro
Gupta Dhanak, Savva Jill, Li Xuan, Chandler James H, Shelton Richard M, Scheven Ben A, Mulvana Helen, Valdastri Pietro, Lucas Margaret, Walmsley A Damien
Ultrasound in Medicine and Biology Vol 48, pp. 1745-1761 (2022)
https://doi.org/10.1016/j.ultrasmedbio.2022.05.001
Contrast enhanced magneto-motive ultrasound in lymph nodes - modelling and pre-clinical imaging using magnetic microbubbles
Sjöstrand Sandra, Bacou Marion, Thomson Adrian, Kaczmarek Katarzyna, Evertsson Maria, Svensson Ingrid, Farrington Susan M, Moug Susan, Jansson Tomas, Moran Carmel M, Mulvana Helen
2022 44th Annual International Conference of the IEEE Engineering in Medicine & Biology Society (EMBC) Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference, pp. 194-197 (2022)
https://doi.org/10.1109/embc48229.2022.9871876
Modelling of magnetic microbubbles to evaluate contrast enhanced magneto-motive ultrasound in lymph nodes – a pre-clinical study
Sjöstrand Sandra, Bacou Marion, Kaczmarek Katarzyna, Evertsson Maria, Svensson Ingrid K, Thomson Adrian JW, Farrington Susan M, Moug Susan J, Jansson Tomas, Moran Carmel, Mulvana Helen
British Journal of Radiology Vol 95 (2022)
https://doi.org/10.1259/bjr.20211128
3D printing of noncytotoxic high-resolution microchannels in Bisphenol-a ethoxylate dimethacrylate tissue-mimicking materials
Domingo-Roca Roger, Gilmour Lauren, Dobre Oana, Sarrigiannidis Stylianos, Sandison Mairi E, O'Leary Richard, Mulvana Helen E
3D Printing and Additive Manufacturing (2022)
https://doi.org/10.1089/3dp.2021.0235
3D-printed high-resolution microchannels for contrast enhanced ultrasound research
Domingo-Roca Roger, Gilmour Lauren, Asciak Lisa, Sarrigiannidis Stylianos, Dobre Oana, Salmeron-Sanchez Manuel, Sandison Mairi, O'Leary Richard, Jackson-Camargo Joseph, Mulvana Helen
2021 IEEE International Ultrasonics Symposium (IUS) 2021 IEEE International Ultrasonics Symposium, IUS 2021 2021 IEEE Ultrasonics Symposium (IUS), pp. 1-4 (2022)
https://doi.org/10.1109/ius52206.2021.9763442
Non-destructive analysis of the mechanical properties of 3D-printed materials
Domingo-Roca R, Asciak L, Windmill J F C, Mulvana H, Jackson-Camargo J C
Journal of Nondestructive Evaluation Vol 41 (2022)
https://doi.org/10.1007/s10921-022-00854-5

More publications

Professional activities

Contrast enhanced magneto-motive ultrasound for colorectal cancer detection: pre-clinical development
Speaker
25/4/2022
IEEE International Symposium on Biomedical Imaging
Participant
31/3/2022
Pre-clinical development of contrast enhanced magneto-motive ultrasound imaging to aid in colorectal cancer detection and staging
Speaker
3/2022
Physiologically-relevant 3D-printed microchannels to study microbubble ultrasound backscatter
Contributor
24/5/2021
Establishing The University of Strathclyde Early Diagnostics Consortium
Chair
21/5/2021
Panel Discussion: Strategies to Create Supportive Academic and Workplace Experiences and Environments for Women Engineers
Speaker
29/9/2020

More professional activities

Projects

Doctoral Training Partnership 2020-2021 University of Strathclyde | Alfuwaires, Ahmed
Stratoudaki, Theodosia (Principal Investigator) Mulvana, Helen Elizabeth (Co-investigator) Alfuwaires, Ahmed (Research Co-investigator)
01-Jan-2021 - 01-Jan-2025
EPSRC Centre for Doctoral Training in Prosthetics & Orthotics | Hicks, Ben
Mulvana, Helen Elizabeth (Principal Investigator) Buis, Arjan (Co-investigator) Hicks, Ben (Research Co-investigator)
01-Jan-2021 - 01-Jan-2025
EPSRC Centre for Doctoral Training in Future Ultrasonic Engineering (FUSE) | Orthodoxou, Andrea 
Mulvana, Helen Elizabeth (Principal Investigator) Orthodoxou, Andrea  (Research Co-investigator)
13-Jan-2021 - 13-Jan-2025
Doctoral Training Partnership 2020-2021 University of Strathclyde | Gilmour, Lauren
Mulvana, Helen Elizabeth (Principal Investigator) Jackson, Joseph (Co-investigator) Gilmour, Lauren (Research Co-investigator)
01-Jan-2020 - 01-Jan-2024
Transformative Anatomically accurate Microvascular flow Phantoms for Ultrasound therapy research (TAMP-US)
Mulvana, Helen Elizabeth (Principal Investigator) Jackson, Joseph (Co-investigator) O'Leary, Richard (Co-investigator) Sandison, Mairi (Co-investigator)
01-Jan-2020 - 31-Jan-2021
VisNET Collaboration Event Social Dinner
Mulvana, Helen Elizabeth (Principal Investigator) Aranceta-Garza, Alejandra (Co-investigator) Zimbitas, Georgina (Co-investigator) Fabbri, Federica (Co-investigator) Keating, Ciara (Co-investigator) Echavarri Bravo, Virginia (Co-investigator)
International collaboration Dinner event funded by the Royal Society of Chemistry for a total value of £2,903.30
24-Jan-2019 - 25-Jan-2019

More projects