Dr Chris John Price

Epsrc Manufacturing Fellow

Chemical and Process Engineering

Personal statement

I am passionate about particles, especially how we can influence their formation by controlling crystallization to deliver particles with physical attributes designed to deliver optimal performance in formulated products. I have recently moved from managing particle science related innovation and product development in the pharmaceutical industry to pursue fundamental research in crystallization focussing on enhancing the purification of organic molecules by active intervention during the crystal growth process.

Publications

Development of a novel continuous filtration unit for pharmaceutical process development and manufacturing
Ottoboni Sara, Price Chris J, Steven Christopher, Meehan Elizabeth, Barton Alastair, Firth Paul, Mitchell Andy, Tahir Furqan
Journal of Pharmaceutical Sciences Vol 108, pp. 372-381 (2019)
https://doi.org/10.1016/j.xphs.2018.07.005
Enabling precision manufacturing of active pharmaceutical ingredients : workflow for seeded cooling continuous crystallisation
Brown Cameron J, McGlone Thomas, Yerdelen Stephanie, Srirambhatla Vijay, Mabbott Fraser, Gurung Rajesh, Briuglia Maria L, Ahmed Bilal, Polyzois Hector, McGinty John, Perciballi Francesca, Fysikopoulos Dimitris, Macfhionnghaile Pól, Siddique Humera, Raval Vishal, Harrington Tomás S, Vassileiou Antony, Robertson Murray, Prasad Elke, Johnston Andrea, Johnston Blair, Nordon Alison, Srai Jagjit, Halbert Gavin, Ter Horst Joop H, Price Chris J, Rielly Chris D, Sefcik Jan, Florence Alastair J
Molecular Systems Design & Engineering Vol 2018, pp. 518-549 (2018)
https://doi.org/10.1039/C7ME00096K
Enabling precision manufacturing of active pharmaceutical ingredients : workflow for seeded cooling continuous crystallisations
Brown Cameron J, McGlone Thomas, Yerdelen Stephanie, Srirambhatla Vijay, Mabbott Fraser, Gurung Rajesh, Briuglia Maria L, Ahmed Bilal, Polyzois Hector, Mcginty John, Perciballi Francesca, Fysikopoulos Dimitris, Macfhionnghaile Pól, Siddique Humera, Raval Vishal, Harrington Tomás S, Vassileiou Antony D, Robertson Murray, Prasad Elke, Johnston Andrea, Johnston Blair, Nordon Alison, Srai Jagjit S, Halbert Gavin, ter Horst Joop H, Price Chris J, Rielly Chris D, Sefcik Jan, Florence Alastair J
Molecular Systems Design and Engineering Vol 3, pp. 518-549 (2018)
https://doi.org/10.1039/c7me00096k
Impact of paracetamol impurities on face properties : investigating the surface of single crystals using TOF-SIMS
Ottoboni Sara, Chrubasik Michael, Mir Bruce Layla, Nguyen Thai Thu Hien, Robertson Murray, Johnston Blair, Oswald Iain D H, Florence Alastair, Price Chris
Crystal Growth and Design Vol 18, pp. 2750–2758 (2018)
https://doi.org/10.1021/acs.cgd.7b01411
Elucidating the mechanism of paracetamol sonocrystallization for product purity enhancement
Forbes Clarissa, Nguyen Thai T H, O'Leary Richard L, Price Chris J
Proceedings of Meetings on Acoustics Vol 32 (2018)
The effect of ultrasound on the crystallisation of paracetamol in the presence of structurally similar impurities
Nguyen Thai T H, Khan Azeem, Bruce Layla M, Forbes Clarissa, O'Leary Richard, Price Chris J
Crystals (2017)
https://doi.org/10.3390/cryst7100294

more publications

Professional activities

What the pharmaceutical industry needs from fine particles
Contributor
7/2/2017
Industrial Crystallization: Batch & Continuous
Speaker
17/1/2017
Impurities: A neglected challenge
Contributor
1/12/2016
Crystallizing and isolating pharmaceuticals: Addressing some of the remaining challenges
Contributor
26/10/2016
Talk to your crystallographer - Essential conversations and critical relationships for partners in Directed Assembly
Contributor
20/7/2016
How does the pharmaceutical industry bring a new drug to market. Why crystallize it continuously? What is the role of ultrasound?
Contributor
25/5/2016

more professional activities

Projects

AZ compounds for evaluation in Continuous Filtration Device
Price, Chris John (Principal Investigator)
05-Jan-2017 - 07-Jan-2018
Doctoral Training Partnership (DTP 2016-2017 University of Strathclyde) | Shahid, Muhid
Price, Chris John (Principal Investigator) Lue, Leo (Co-investigator) Shahid, Muhid (Research Co-investigator)
01-Jan-2017 - 01-Jan-2021
Future Continuous Manufacturing and Advanced Crystallisation Research Hub (CMAC Hub)
Florence, Alastair (Principal Investigator) Halbert, Gavin (Co-investigator) Johnston, Blair (Co-investigator) Nordon, Alison (Co-investigator) Price, Chris John (Co-investigator) Sefcik, Jan (Co-investigator) Ter Horst, Joop (Co-investigator)
01-Jan-2017 - 31-Jan-2023
KTP - Alconbury Weston
Price, Chris John (Principal Investigator) Mulheran, Paul (Co-investigator)
18-Jan-2016 - 01-Jan-2018
Assessment of continuous filter unit and assessment of filter cake washing efficiency (student secondment)
Price, Chris John (Principal Investigator)
23-Jan-2015 - 22-Jan-2017
Doctoral Training Centre In Continuous Manufacturing And Crystallisation | Ottoboni, Sara
Price, Chris John (Principal Investigator) Nordon, Alison (Co-investigator) Ottoboni, Sara (Research Co-investigator)
01-Jan-2014 - 12-Jan-2018

more projects

Address

Chemical and Process Engineering
James Weir Building

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