Postgraduate research opportunities

New Metal-Catalysed Methods for C-H Activation Processes

This project will explore new methods for directed meta-C-H activation to deliver complementary, flexible, and powerful methods to access a variety of pharmaceutically desired organic products and isotopically labelled late stage candidate-type molecules.

Number of places

1

Funding

Home fee, Equipment costs, Travel costs, Stipend

Opens

29 April 2021

Deadline

21 May 2021

Duration

This 4 year studentship is available starting October 2021.

Eligibility

Applicants must have, or expect to obtain, a strong MChem (or equivalent) degree as a requirement of the funding. Additionally, the position is well suited to students with significant experience in Synthetic Organic Chemistry obtained either through industrial placement or as part of an MChem/MSci research project.

Project Details

The general interests of the Lindsay and Kerr laboratories cover a broad range of metal-mediated synthetic organic chemistry and, in particular, in the development of new preparative techniques, the creation of asymmetric processes, and the use of these emerging methods in total synthesis programmes.

The available project will explore new methods for directed meta-C-H activation using new catalyst classes developed at Strathclyde, which have grown from state-of-the-art ortho-C-H activation catalysis. These new methods will deliver complementary, flexible, and powerful methods to access a variety of pharmaceutically desired organic products and isotopically labelled late stage candidate-type molecules. As part of the overall programme of work, computationally-driven methods will be used to inform catalyst design and investigate reaction mechanism, in addition to directing the emerging reaction scope.

The successful applicant will join an extremely motivated and industrious research team, and will receive elevated levels of training in the areas of preparative chemistry, organometallic-based synthesis, reaction mechanism, computational methods, and the associated analytical/spectroscopic requirements.

Funding Details

This studentship is funded in collaboration with the EPSRC and the world-leading pharmaceutical company, GSK, for a duration of 4 years. Additionally, GSK will fully support a 3-month secondment at their Stevenage site, allowing the associated student to maximise the potential for knowledge exchange and engagement with the wider scientific community.  

How to apply

Please submit your application by e-mail to Dr Laura C. Paterson (laura.c.paterson@strath.ac.uk), which should include:

  • a cover letter, detailing your experience and motivation for PhD studies
  • a CV with two referees’ details included
  • Full transcripts from your undergraduate degree and any previous postgraduate studies
  • Other pertinent information (e.g., publications, awards, and other distinctions)