Postgraduate research opportunities Molecular Design for Drug Discovery
ApplyKey facts
- Opens: Friday 4 March 2022
- Number of places: 1
- Duration: 36 months
Overview
The project will take a biophysical approach to studying molecular recognition events in a ligand/nucleic acid context. It will use NMR spectroscopy, in silico modelling and associated analytical chemistry methods that will lead to better knowledge of the factors affecting these molecular recognition processes.Eligibility
Candidates should hold or expect to hold a first or upper second class (Bachelors or Masters) degree in a relevant discipline (chemistry, biophysics or related areas).
Project Details
Drug resistance is a growing concern for the future of effective medicine. For this reason, new paradigms in drug design are actively being sought. This PhD project will take a biophysical approach to investigating molecular recognition processes between potential drug molecules and their nucleic acid targets. It will involve NMR spectroscopy for data collection and in silico modelling alongside associated analytical chemistry techniques that will lead to a fuller understanding of the subtle factors which play their role in these molecular recognition processes. Scope exists for developing new concepts in drug design as part of this research drive alongside new experimental methods to better explore the complex data analysis problem.
The student will join a small team of analytical and synthetic chemists within an NMR laboratory setting. They will become expert in the application of NMR spectroscopy and in silico methods to nucleic acid/drug recognition systems. World-class training will be provided to develop the student into an independent professional researcher through Strathclyde’s extensive Researcher Development Programme.
Funding details
The student will require to self-fund or hold a scholarship, for example, from an international body.
Apply
Applicants should submit a CV by email to: john.parkinson@strath.ac.uk
Number of places: 1
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Contact us
- Dr. John Parkinson, john.parkinson@strath.ac.uk
- Dr. Fraser Scott, fraser.j.scott@strath.ac.uk