- Opens: Tuesday 7 April 2020
- Number of places: 1
- Duration: Up to 4 years
- Funding: Equipment costs, Travel costs
OverviewThe discovery of new medicines to treat disease requires the identification, understanding and validation of biological pathways and targets. This project resides in the Healthcare technologies theme, aligning with the growth area of Chemical Biology and the areas of Analytical Science and Synthetic Organic Chemistry.
Altering the redox environment within a cell can give rise to changes that result in disease. The ability to sense and determine a cellular redox potential would allow for basic biological investigation and the discovery of new targets for drug discovery. We will develop environmentally sensitive Raman active probe molecules capable of determining the redox environment in cells using bioinformatics and AI technologies to understand the data generated.