Dr Geoffrey Coxon

Lecturer

Strathclyde Institute of Pharmacy and Biomedical Sciences

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Personal statement

Dr Geoff Coxon is a lecturer in Medicinal Chemistry. After receiving his PhD from the University of Newcastle upon Tyne, and a short term industry, he moved SIPBS where he set up his research group in the discovery and development of new agents to treat tuberculosis. He is the co-founder and Deputy Leader of TB Drug Discovery UK (www.tbd-uk.org.uk). In this role he works with fellow scientists and clinicians, UK government policy makers and advocates with the goal of strengthening scientific research across all areas of TB drug development as a key part of the UK response in the global eradiation of the disease.

The links here take you to the TBD-UK profile  page of Dr Geoff Coxon and the TBD-UK website home page

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Publications

Resistance to thiacetazone derivatives active against Mycobacterium abscessus involves mutations in the MmpL5 transcriptional repressor MAB_4384
Halloum Iman, Viljoen Albertus, Khanna Varun, Craig Derek, Bouchier Christiane, Brosch Roland, Coxon Geoffrey, Kremer Laurent
, pp. e02509-16:1-14 (2017)
https://doi.org/10.1128/AAC.02509-16
Characterisation of triterpenes and new phenolic lipids in Cameroonian propolis
Kardar M N, Zhang T, Coxon G D, Watson D G, Fearnley J, Seidel V
Phytochemistry Vol 106, pp. 156-163 (2014)
https://doi.org/10.1016/j.phytochem.2014.07.016
Synthesis, antitubercular activity and mechanism of resistance of highly effective thiacetazone analogues
Coxon Geoffrey, Craig Derek, Corrales Rosa Milagros, Vialla Emilie, Gannoun-Zaki Laila, Kremer Laurent
PLOS One Vol 8, pp. 1-13 (2013)
https://doi.org/10.1371/journal.pone.0053162
Strategies and challenges involved in the discovery of new chemical entities during early-stage tuberculosis drug discovery
Coxon Geoffrey, Cooper Christopher B, Gillespie Stephen H, McHugh Timothy D
Journal of Infectious Diseases (2012)
https://doi.org/10.1093/infdis/jis191
Synthesis of cis,cis-diunsaturated α-meromycolic acid by a palladium-catalysed alkyl–alkyl Negishi reaction
Berretta Giacomo, Coxon Geoffrey
Tetrahedron Letters Vol 53, pp. 214-216 (2012)
https://doi.org/10.1016/j.tetlet.2011.11.021
Oral evidence to the International Development Committee
Coxon Geoffrey
Department for International Development Summit (2012)

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Professional Activities

Gordon Research conference on TB Drug Development
Keynote/plenary speaker
8/2009
International Symposium on Tuberculosis , India
Keynote/plenary speaker
1/2008

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Projects

DTP 2224 University of Strathclyde | Evdokimou, Maria
Perrie, Yvonne (Principal Investigator) Coxon, Geoffrey (Co-investigator) Evdokimou, Maria (Research Co-investigator)
01-Jan-2023 - 01-Jan-2027
DTP 2224 University of Strathclyde | Cairns, Michael
Coxon, Geoffrey (Principal Investigator) Perrie, Yvonne (Co-investigator) Cairns, Michael (Research Co-investigator)
01-Jan-2023 - 01-Jan-2027
ICDDC - Interacellular Drug Delivery Centre
Perrie, Yvonne (Principal Investigator) Coxon, Geoffrey (Co-investigator)
01-Jan-2023 - 31-Jan-2026
Pharmacy Elementals
Coxon, Geoffrey (Principal Investigator)
21-Jan-2022 - 31-Jan-2023
TB Drug Development-UK (TBD-UK)
Coxon, Geoffrey (Principal Investigator)
20-Jan-2009 - 30-Jan-2012
Thiolactomycin and related inhibitors targeting fatty acid elongase enzymes in Mycobacterium tuberculosis
MacKay, Simon (Principal Investigator) Coxon, Geoffrey (Co-investigator) Johnston, Blair (Co-investigator)
01-Jan-2005 - 30-Jan-2008

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Contact

Dr Geoffrey Coxon
Lecturer
Strathclyde Institute of Pharmacy and Biomedical Sciences

Email: geoff.coxon@strath.ac.uk
Tel: 548 5754