Professor Karen Faulds

Pure and Applied Chemistry

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Publications

Cytokeratin-18 is a sensitive biomarker of alanine transaminase increase in a placebo-controlled, randomized, crossover trial of therapeutic paracetamol dosing (PATH-BP biomarker substudy)
Scullion Kathleen M, MacIntyre Iain M, Sloan-Dennison Sian, Clark Benjamin, Fineran Paul, Mair Joanne, Creasey David, Rathmell Cicely, Faulds Karen, Graham Duncan, Webb David J, Dear James W
Toxicological Sciences (2024)
https://doi.org/10.1093/toxsci/kfae031
Plasmonic and photothermal properties of silica-capped gold nanoparticle aggregates
Fergusson Jodie, Wallace Gregory Q, Sloan-Dennison Sian, Carland Ruairí, Shand Neil C, Graham Duncan, Faulds Karen
Journal of Physical Chemistry C Vol 127, pp. 24475-24486 (2023)
https://doi.org/10.1021/acs.jpcc.3c07536
Spectral fingerprinting of cellular lipid droplets using stimulated Raman scattering microscopy and chemometric analysis
Rensonnet Aurélie, Tipping William J, Malherbe Cedric, Faulds Karen, Eppe Gauthier, Graham Duncan
Analyst Vol 149, pp. 553-562 (2023)
https://doi.org/10.1039/D3AN01684F
Expanding the range of bioorthogonal tags for multiplex stimulated Raman scattering microscopy
Murphy Neville, Tipping William J, Braddick Henry J, Wilson Liam T, Tomkinson Nicholas CO, Faulds Karen, Graham Duncan, Farràs Pau
Angewandte Chemie International Edition Vol 62 (2023)
https://doi.org/10.1002/anie.202311530
Optoplasmonic effects in highly curved surfaces for catalysis, photothermal heating, and SERS
Masson Jean-Francois, Wallace Gregory Q, Asselin Jérémie, Ten Andrey, Hojjat Jodaylami Maryam, Faulds Karen, Graham Duncan, Biggins John S, Ringe Emilie
ACS Applied Materials and Interfaces Vol 15, pp. 46181–46194 (2023)
https://doi.org/10.1021/acsami.3c07880
Light-up split aptamers : binding thermodynamics and kinetics for sensing
Zhao Yichen, Patel Nikesh, Sun Peihuan, Faulds Karen, Graham Duncan, Liu Juewen
Analyst Vol 148, pp. 5612-5618 (2023)
https://doi.org/10.1039/D3AN01368E

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Research Interests

Our research focuses on using surface enhanced Raman scattering (SERS) to create new approaches to bioanalysis for use in the life and clinical sciences.  SERS is a spectroscopic technique that offers significant advantages over other established techniques such as fluorescence and our research has focused on highlighting the advantages, creating new examples of increased capability in life science applications and interacting with end users to shape future step changes in research.  Our research centres around using the inherent sensitivity of SERS for the detection of target DNA or proteins using signal amplification methods to enhance the signal rather than using target amplification methods such as PCR.  Our work has focussed on exploiting the sensitivity of SERS for quantitative analysis of biomolecules as well as exploiting one of the key advantages of SERS, the ability to analyse multiple analytes in one sample.  This allows more information to be gained per analysis as well as giving information about complex systems that are intrinsically difficult to measure.

Professional Activities

Development of a Spatially Offset Raman Spectroscopy Probe for Monitoring Pharmaceutical Drying
Contributor
25/1/2024
Development of a Spatially Resolved Spectroscopy probe for In-line Monitoring of Pharmaceutical Drying
Contributor
21/3/2023
Seminar
Invited speaker
11/2022
SciX 2022
Keynote/plenary speaker
10/2022
SciX 2022
Invited speaker
10/2022
Seminar
Invited speaker
9/2022

More professional activities

Projects

Rapid Bacterial Testing
Faulds, Karen (Principal Investigator) Graham, Duncan (Co-investigator)
05-Jan-2024 - 30-Jan-2024
DTP 2224 University of Strathclyde | Merchant, Andrew
Faulds, Karen (Principal Investigator) Graham, Duncan (Co-investigator) Merchant, Andrew (Research Co-investigator)
01-Jan-2023 - 01-Jan-2027
New Capability for Bacterial Testing in the Food Production Environment
Faulds, Karen (Principal Investigator) Graham, Duncan (Co-investigator) May, Hayleigh (Research Co-investigator)
01-Jan-2022 - 31-Jan-2024
Strathclyde CDT: Healthcare Nanotechnologies
Perrie, Yvonne (Principal Investigator) Rattray, Zahra (Principal Investigator) Hoskins, Clare (Principal Investigator) Faulds, Karen (Principal Investigator) Graham, Duncan (Principal Investigator)
01-Jan-2022 - 30-Jan-2025
DTP 2224 University of Strathclyde | Gale, Cameron
Faulds, Karen (Principal Investigator) Graham, Duncan (Co-investigator) Gale, Cameron (Research Co-investigator)
01-Jan-2022 - 01-Jan-2026
EPSRC IAA: PROSPECTIVE SPINOUT: Rapid Bacterial Testing (RBT)
Faulds, Karen (Co-investigator)
01-Jan-2022 - 31-Jan-2025

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Contact

Professor Karen Faulds
Pure and Applied Chemistry

Email: karen.faulds@strath.ac.uk
Tel: 548 2507