Dr Paul Hoskisson

Reader

Strathclyde Institute of Pharmacy and Biomedical Sciences

Personal statement

Laboratory webpage is here http://paulhoskisson.weebly.com

Research in my group is focussed on the synthesis of antibiotics and the evolution of bacterial pathogens, using a range of techniques from molecular biology and biochemistry through to mathematical modelling and image analysis. The bacterial genus Streptomyces is the main focus of work in my Research Group due to its industrial importance, being responsible for producing around two thirds of all commercially important antibiotics as well as numerous anti-fungal, anti-helminthic and anti-cancer drugs. 

We also have an interest in evolution of metabolism, evolution of bacterial pathogens, genomics of actinobacteria and the exploitation of amphibian proteins for biotechnology. 

We use a range of techniques to study the biology of actinobacteria including molecular genetics, protein biochemistry, genomics, microscopy, physiology, advanced spectroscopy, mathematical modeling and bioinformatics.

I was elected as a member of the Royal Society of Edinburgh Young Academy of Scotland in 2014 and a Fellow of the Royal Society of Biology (FRSB) in 2016.

I am a member of the Microbiology Society, the American Society of Microbiology, the Biochemical Society, The Royal Society of Biology and British Herpetological Society.

I am a managing editor for Antonie van Leeuwenhoek International Journal of Microbiology, and sit on the editorial board for Microbial Genomics, Frontiers in Antimicrobials, resistance and chemotherapy, Frontiers in Microbial Physiology and Metabolism, Frontiers in Synthetic Biology and Metabolism and Nature Scientific Data and Nature Scientific Reports.I am a former Editor in Chief of Microbiology Today.

I am a Fellow of the Higher Education Academy.

I am interested in the use of Social media for communication of science and you can follow on Twitter @paulhoskisson

Publications

Development and application of an eDNA method to detect the critically endangered trinidad golden tree frog (Phytotriades auratus) in bromeliad phytotelmata
Brozio Sarah, Manson Chloe, Gourevitch Eleanor, Burns Thomas J., Greener Mark S., Downie J. Roger, Hoskisson Paul A.
PLOS1 Vol 12, (2017)
http://dx.doi.org/10.1371/journal.pone.0170619
Growth rate control of flagellar assembly in Escherichia coli strain RP437
Sim Martin, Koirala Santosh, Picton David, Strahl Henrik, Hoskisson Paul A., Rao Christopher V., Gillespie Colin S., Aldridge Phillip D.
Scientific Reports Vol 7, pp. 1-11, (2017)
http://dx.doi.org/10.1038/srep41189
Coordinate regulation of antimycin and candicidin biosynthesis
McLean Thomas C., Hoskisson Paul A., Seipke Ryan F.
mSphere, pp. 1-35, (2016)
Next-generation systematics : an innovative approach to resolve the structure of complex prokaryotic taxa
Sangal Vartul, Goodfellow Michael, Jones Amanda L., schwalbe Edward C., Blom Jochen, Hoskisson Paul A., Sutcliffe Iain C.
Scientific Reports, (2016)
Evolution, epidemiology and diversity of Corynebacterium diphtheriae : new perspectives on an old foe
Sangal Vartul, Hoskisson Paul A.
Infection, Genetics and Evolution Vol 43, pp. 364-370, (2016)
http://dx.doi.org/10.1016/j.meegid.2016.06.024
Adherence and invasive properties of Corynebacterium diphtheriae strains correlates with the predicted membrane-associated and secreted proteome
Sangal Vartul, Blom Jochen, Sutcliffe Iain C., von Hunolstein Christina, Burkovski Andreas, Hoskisson Paul A.
BMC Genomics Vol 16, (2015)
http://dx.doi.org/10.1186/s12864-015-1980-8

more publications

Professional activities

Royal Society of Biology (External organisation)
Member
1/1/2016
BBSRC (Biotech & Biological Sciences Research Council) (External organisation)
Member
1/10/2015
Royal Society of Edinburgh (External organisation)
Member
1/7/2014
Scientific Data (Journal)
Editor
2013
Society for General Microbiology
Participant
9/2012
Society for General Microbiology
Organiser
26/3/2012

more professional activities

Projects

Microfluidic manufacturing and development of a novel clostridium difficile oral vaccine | Forbes, Neil Liam Andrew
Perrie, Yvonne (Principal Investigator) Hoskisson, Paul (Co-investigator) Forbes, Neil Liam Andrew (Research Co-investigator)
Period 01-Oct-2016 - 01-Oct-2019
Establishing an integrated biocatalytic Friedel-Crafts platform for the alkylation of aromatic small molecules | McKean, Iain
Burley, Glenn (Principal Investigator) Hoskisson, Paul (Co-investigator) McKean, Iain (Research Co-investigator)
Period 01-Oct-2015 - 01-Oct-2019
David Begg Studentship | Brozio, Sarah
Hoskisson, Paul (Principal Investigator) Brozio, Sarah (Research Co-investigator)
Period 01-Oct-2014 - 01-Apr-2018
Assessing the biotechnological potential of Antarctic and sub Arctic sediment cores (MASTS funding)
Duncan, Katherine (Principal Investigator) Hoskisson, Paul (Co-investigator)
Period 05-Dec-2016 - 11-Aug-2017
Development of Streptomyces strains to use sustainable feedstocks in fermentations
Hoskisson, Paul (Principal Investigator)
Period 01-Oct-2016 - 31-Mar-2020
Development of Stable Streptomyces clavuligeris strains for improved clavalunic acid production
Herron, Paul (Principal Investigator) Hoskisson, Paul (Co-investigator)
Period 01-Oct-2016 - 31-Mar-2020

more projects

Address

Strathclyde Institute of Pharmacy and Biomedical Sciences

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