Publications

Deep generative models for pharmaceutical manufacturing process design

Alvarado D, Johnston BF, Brown CJ

Chemical Engineering Research and Design Vol 230, pp. 571-585 (2026)

https://doi.org/10.1016/j.cherd.2026.05.001

The effect of API on the disintegration of tablets

Armstrong John, MacLean Natalie, Markl Daniel, Johnston Blair

10th World Congress on Particle Technology (2026)

From synthesis to product : data traceability in CMAC's data fabric

Armstrong John, Boyle Christopher, Naz Tabbasum, Robertson Murray, Jolliffe Hikaru Graeme, Gahler Daniel, Soltani Pooria, Abbas Faisal, Salehian Mohammad, Pickles Thomas, Fleming Megan, Booth David, Goldie Jonathan, McGlone Thomas, Prostredny Martin, Johnston Blair, Florence Alastair

CMAC Open Days 2026 (2026)

A case study on hybrid machine learning and quantum-informed modelling for solubility prediction of drug compounds in organic solvents

Wang Weiling, Cooley Isabel, Alexander Morgan R, Wildman Ricky D, Croft Anna K, Johnston Blair F

Digital Discovery Vol 5, pp. 716-733 (2026)

https://doi.org/10.1039/d5dd00456j

Quality by digital design in action : a workflow for crystallisation and isolation

Houson Ian, Siddique Humera, Chong Magdalene WS, Robertson Murray, Turner Alice J, Nordon Alison, Osman Amal, Galindo Amparo, Dunn Andrew S, Johnston Blair, Benyahia Brahim, Brown Cameron J, Mustoe Chantal L, Price Chris J, Reilly Chris D, Adjiman Claire S, Jackson George, Prasad Elke, Halbert Gavin, Feilden Helen, Sefcik Jan, McGinty John, Robertson John, Smith Kenneth, Al-Attili Mais, McGowan Mark, Siddique Mariam, Pathan Momina, Rajoub Nazer, Hamilton Niki, Feeney Rachel, Brown Scott, Urwin Stephanie J, Bernet Thomas, Pickles Thomas, Li Wei, Florence Alastair J

International Journal of Pharmaceutics Vol 686 (2025)

https://doi.org/10.1016/j.ijpharm.2025.126343

Predictive approaches for 3D ‐printing : Methods and approaches for polymeric materials

Cooley Isabel, Wang Weiling, Kozyrev Vladimir, Wildman Ricky D, Johnston Blair F, Croft Anna K

Wiley Interdisciplinary Reviews: Computational Molecular Science Vol 15 (2025)

https://doi.org/10.1002/wcms.70048

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Research Interests

Dr Blair Johnston is a Reader in Computational Modelling at the Strathclyde Institute of Pharmacy and Biomedical Sciences. He teaches on the Masters of Pharmacy, Pharmaceutical Analysis, Clinical Pharmacy and Chemistry with Drug Discovery degrees.

My group has research interests in five broad areas: drug discovery, molecular structure simulation, machine learning and prediction, data analysis, and web-enabled science and collaboration tools. In the vast majority of our research, we work closely with experimental scientists in the design and execution of collaborative research to realise the full potential of their laboratory data. This combination of experiment and theory often provides unique insight into the systems being studied.

Professional Activities

Data Mining Crystallisation Kinetics

Contributor

31/3/2021

Novel off-target effects of doxorubicin on cardiovascular gap-junctional proteins

Contributor

5/2/2021

P011 - Endothelial connexin-43 dysregulation in response to the anthracycline doxorubicin

Contributor

14/12/2020

P2.5.6 - Novel off-target effects of anti-cancer drugs on cardiovascular gap-junctional proteins

Contributor

12/10/2020

Data Mining Crystallisation Kinetics

Contributor

19/8/2020

Cambridge Crystallographic Data Centre (CCDC) European UGM and Science Day

Participant

13/6/2019

More professional activities

Projects

DTP 2224 University of Strathclyde | Paterson, Fraser

Florence, Alastair (Principal Investigator) Johnston, Blair (Co-investigator) Prostredny, Martin (Co-investigator) Paterson, Fraser (Research Co-investigator)

01-Jan-2025 - 01-Jan-2029

CERSI for the Digital Transformation of Medicines Development and Manufacturing

Markl, Daniel (Principal Investigator) Florence, Alastair (Co-investigator) Johnston, Blair (Co-investigator)

01-Jan-2025 - 31-Jan-2026

DPN-MED: Digital Plug-and-Produce Network for Sustainable Medicines Development and Manufacturing

Fitzpatrick, Stephen (Principal Investigator) Florence, Alastair (Principal Investigator) Florence, Alastair (Co-investigator) Johnston, Blair (Co-investigator) Markl, Daniel (Co-investigator)

01-Jan-2025 - 30-Jan-2025

EPSRC MediForge Hub: An Integrated, Reconfigurable and Cyberphysical Manufacturing Platform for Resilient and Sustainable Medicines Manufacture (Manufacturing Research Hub)

Florence, Alastair (Principal Investigator) Brown, Cameron (Co-investigator) Cardona Amengual, Javier (Co-investigator) Johnston, Blair (Co-investigator) Markl, Daniel (Co-investigator) Nordon, Alison (Co-investigator) Robertson, John (Co-investigator) Sefcik, Jan (Co-investigator)

01-Jan-2024 - 30-Jan-2031

EPSRC Centre for Doctoral Training in Cyber-physical Systems for Medicine Development and Manufacturing (CEDAR) | Shearer, Andrew

Johnston, Blair (Principal Investigator) Oswald, Iain (Co-investigator) Shearer, Andrew (Research Co-investigator)

01-Jan-2024 - 01-Jan-2032

PharmaCrystNet: Improving the Predictive Capabilities of Crystallisation Models in

Brown, Cameron (Principal Investigator) Dolean Maini, Victorita (Co-investigator) Johnston, Blair (Co-investigator)

01-Jan-2024 - 28-Jan-2026

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