Dr Lian Tian
Lecturer
Strathclyde Institute of Pharmacy and Biomedical Sciences
Personal statement
Personal statement
Lian obtained his PhD in Mechanical Engineering from the University of Colorado at Boulder in 2010. He then took his first postdoctoral training in Biomedical Engineering at the University of Wisconsin-Madison in USA and his second postdoctoral training in biology at Queen's University in Canada. He Joined SIPBS in 2020. His research interest is cardiovascular physiology, biomechanics and biology, particularly in pulmonary hypertension. His group has recently focused on right ventricular fibrosis and function in pulmonary hypertension.
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Prize And Awards
- Sir David Anderson Bequest Award
- Recipient
- 10/2023
- Canadian Vascular Network trainee Travel Award for the Young Investigator Forum at Canadian Hypertension Congress
- Recipient
- 2019
- Outstanding Oral Presentation at Canadian Hypertension Congress
- Recipient
- 2019
- Queen’s University Post-Doctoral Travel Award
- Recipient
- 2018
- ATS the Assembly on Pulmonary Circulation (PC) Abstract Scholarship
- Recipient
- 2018
- AHA 3CPR Junior Investigator Travel Stipend
- Recipient
- 2016
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Publications
- Using LDDMM and a kinematic cardiac growth model to quantify growth and remodelling in rat hearts under PAH
- Guan Debao, Tian Lian, Li Wei, Gao Hao
- Computers in Biology and Medicine Vol 171 (2024)
- https://doi.org/10.1016/j.compbiomed.2024.108218
- The effects of mitochondrial dysfunction on the cell cycle
- Wu Danchen, Tian Lian, Hoskin Victoria, Dasgupta Asish
- Frontiers in Cell and Developmental Biology Vol 11 (2023)
- https://doi.org/10.3389/fcell.2023.1303834
- An integrated proteomic and transcriptomic signature of the failing right ventricle in monocrotaline induced pulmonary arterial hypertension in male rats
- Hindmarch Charles Colin Thomas, Tian Lian, Xiong Ping Yu, Potus Francois, Bentley Rachel Emily Teresa, Al-Qazazi Ruaa, Prins Kurt W, Archer Stephen L
- Frontiers in Physiology Vol 13 (2022)
- https://doi.org/10.3389/fphys.2022.966454
- Macrophage-NLRP3 activation promotes right ventricle failure in pulmonary arterial hypertension
- Al-Qazazi Ruaa, Lima Patricia DA, Prisco Sasha Z, Potus Francois, Dasgupta Asish, Chen Kuang-Hueih, Tian Lian, Bentley Rachel E T, Mewburn Jeff, Martin Ashley Y, Wu Danchen, Jones Oliver, Maurice Donald H, Bonnet Sebastien, Provencher Steeve, Prins Kurt W, Archer Stephen L
- American Journal of Respiratory and Critical Care Medicine Vol 206, pp. 608-624 (2022)
- https://doi.org/10.1164/rccm.202110-2274OC
- Inhibiting pyruvate kinase muscle isoform 2 regresses group 2 pulmonary hypertension induced by supra-coronary aortic banding
- Xiong Ping Yu, Motamed Mehras, Chen Kuang-Hueih, Dasgupta Asish, Potus François, Tian Lian, Martin Ashley, Mewburn Jeffrey, Jones Oliver, Thébaud Arthur, Archer Stephen L
- Acta Physiologica Vol 234 (2022)
- https://doi.org/10.1111/apha.13764
- PINK1-induced phosphorylation of mitofusin 2 at serine 442 causes its proteasomal degradation and promotes cell proliferation in lung cancer and pulmonary arterial hypertension
- Dasgupta Asish, Chen Kuang-Hueih, Lima Patricia DA, Mewburn Jeffrey, Wu Danchen, Al-Qazazi Ruaa, Jones Oliver, Tian Lian, Potus Francois, Bonnet Sebastien, Archer Stephen L
- FASEB Journal Vol 35 (2021)
- https://doi.org/10.1096/fj.202100361R
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Research Interests
Cardiovascular physiology, biomechanics, biology and modeling in pulmonary hypertension
Professional Activities
- Biochemical and Biophysical Research Communications (Journal)
- Peer reviewer
- 3/2024
- Targeting right ventricular diastolic dysfunction, fibrosis and ischemia in pulmonary arterial hypertension
- Speaker
- 4/10/2023
- Cellular Signalling (Journal)
- Peer reviewer
- 10/2023
- International Journal of Cardiology (Journal)
- Peer reviewer
- 9/2023
- Journal of Biomechanical Engineering (Journal)
- Peer reviewer
- 1/8/2023
- Graz University of Technology
- Visiting researcher
- 27/7/2023
Projects
- Novel therapies targeting the right ventricle in pulmonary arterial hypertension
- Tian, Lian (Principal Investigator)
- 01-Jan-2023 - 31-Jan-2025
- Sex-dependent mitochondrial function in right ventricle in pulmonary arterial hypertension
- Tian, Lian (Principal Investigator)
- 01-Jan-2021 - 31-Jan-2021
- Doctoral Training Partnership 2020-2021 University of Strathclyde | Coyle, Chelbi
- Tian, Lian (Principal Investigator) MacLean, Mandy (Co-investigator) Coyle, Chelbi (Research Co-investigator)
- 01-Jan-2020 - 01-Jan-2024
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Contact
Dr
Lian
Tian
Lecturer
Strathclyde Institute of Pharmacy and Biomedical Sciences
Email: lian.tian@strath.ac.uk
Tel: 0141 548 4968