Personal statement

Contact Details

Department of Pure and Applied Chemistry

University of Strathclyde

Thomas Graham Building, Office TG 507

295 Cathedral Street

Glasgow G1 1XL

Phone: +44 (0)141 548 4648;

Webpage: https://bruns-lab.com/

Email: nico.bruns@strath.ac.uk

Twitter: https://twitter.com/Bruns_Lab; @Bruns_Lab

Google Scholar: Link

ORCID: https://orcid.org/0000-0001-6199-9995

Career Synopsis

2018 – present: Professor of Macromolecular Chemistry, University of Strathclyde
2013 – 2018: Associate Professor of Macromolecular Chemistry, Adolphe Merkle Institute, University of Fribourg, Switzerland
2008 – 2013: Habilitand (Independent Research Group Leader), Department of Chemistry, University of Basel, Switzerland; Habilitation Mentor: Prof. Wolfgang Meier
2007 – 2008: Postdoctoral Researcher with Prof. Douglas S. Clark, Department of Chemical Engineering, University of California, Berkeley, USA
2003 – 2007: PhD in Chemistry with Prof. Rolf Mülhaupt and Jörg C. Tiller, University of Freiburg, Germany

Publications

Pyranine-modified amphiphilic polymer conetworks as fluorescent ratiometric pH sensors: Ulrich Sebastian, Osypova Alina, Panzarasa Guido, Rossi René M, Bruns Nico, Boesel Luciano F; Macromolecular Rapid Communications Vol 40 (2019); https://doi.org/10.1002/marc.201900360
Light-responsive block copolymers with a spiropyran located at the block junction: Apebende Edward A, Dubois Laurent, Bruns Nico; European Polymer Journal Vol 119, pp. 83-93 (2019); https://doi.org/10.1016/j.eurpolymj.2019.06.037
Preface: Bruns Nico, Loos Katja; Methods in Enzymology (2019) (2019); https://doi.org/10.1016/S0076-6879(19)30400-8
Enzyme-initiated free radical polymerizations of vinyl monomers using horseradish peroxidase: Rodriguez Kyle J, Pellizzoni Michela M, Chadwick Robert J, Guo Chao, Bruns Nico; Methods in Enzymology (2019) (2019); https://doi.org/10.1016/bs.mie.2019.08.013
Biocatalytic ATRP in solution and on surfaces: Rodriguez Kyle J, Pellizzoni Michela M, Divandari Mohammad, Benetti Edmondo M, Bruns Nico; Methods in Enzymology (2019) (2019); https://doi.org/10.1016/bs.mie.2019.08.014
Hemozoin-catalyzed precipitation polymerization as an assay for malaria diagnosis: Rifaie-Graham Omar, Pollard Jonas, Raccio Samuel, Balog Sandor, Rusch Sebastian, Hernández-Castañeda María Andrea, Mantel Pierre Yves, Beck Hans Peter, Bruns Nico; Nature Communications Vol 10 (2019); https://doi.org/10.1038/s41467-019-09122-z

more publications

Research interests

Synthetic polymers have contributed to many innovations in all aspects of modern life. Significant progress has been made in synthetic methods to obtain functional polymers, in the fabrication of polymeric nanostructures and in the fundamental understanding of their physicochemical properties. However, compared to the properties and functions of nature’s macromolecules, even the most sophisticated synthetic polymers still appear to be simple and only offer comparably basic functionality. Proteins are fascinating macromolecules, particularly from a polymer chemist’s point of view. The vast variety of functions that proteins can fulfill is not seen in any synthetic material. Enzymes for example act as catalysts, while other proteins fluoresce or control transport across cell membranes. Moreover, certain proteins can self-assemble into nanocontainers and nanoreactors. All these functions are essential molecular mechanisms that enable life and render living tissue responsive and adaptive.

My research encompasses an interdisciplinary, bio-inspired approach that combines polymer chemistry and protein engineering to create new opportunities for the sustainable synthesis of polymers and to design, engineer and realize materials and nanosytems with unprecedented new functions. Examples are the use of enzymes as catalysts for atom transfer radical polymerizations, the use of biocatalysis for malaria diagnostics, to develop polymersome- and protein-based nanoreactors for enzymatic reactions, and to use proteins as force-responsive sensor molecules in fiber-reinforced composite materials.

Group Webpage:

For further information, please visit:

https://bruns-lab.com/

Selected Publications:

Rifaie-Graham, O.; Pollard, J.; Raccio, S.; Balog, S.; Rusch, S.; Hernández-Castañeda, M. A.; Mantel, P.-Y.; Beck, H.-P.; Bruns, N., Hemozoin-catalyzed precipitation polymerization as an assay for malaria diagnosis. Nature Commun. 2019, 10, 1369. Link
Rifaie-Graham, O.; Ulrich, S.; Galensowske, N. F. B.; Balog, S.; Chami, M.; Rentsch, D.; Hemmer, J. R.; Read de Alaniz, J.; Boesel, L. F.; Bruns, N., Wavelength-Selective Light-Responsive DASA-Functionalized Polymersome Nanoreactors. J. Am. Chem. Soc. 2018, 140, 8027-8036. Link
Rother, M.; Barmettler, J.; Reichmuth, A.; Araujo, J. V.; Rytka, C.; Glaied, O.; Pieles, U.; Bruns, N., Self-Sealing and Puncture Resistant Breathable Membranes for Water-Evaporation Applications. Adv. Mater. 2015, 27, 6620-6624. Link
Renggli, K.; Nussbaumer, M. G.; Urbani, R.; Pfohl, T.; Bruns, N., A Chaperonin as Protein Nanoreactor for Atom-Transfer Radical Polymerization. Angew. Chem., Int. Ed. 2014, 53, 1443-1447. Link
Silva, T. B.; Spulber, M.; Kocik, M. K.; Seidi, F.; Charan, H.; Rother, M.; Sigg, S. J.; Renggli, K.; Kali, G.; Bruns, N., Hemoglobin and Red Blood Cells Catalyze Atom Transfer Radical Polymerization. Biomacromolecules 2013, 14, 2703-2712. Link
Sigg, S. J.; Seidi, F.; Renggli, K.; Silva, T. B.; Kali, G.; Bruns, N., Horseradish Peroxidase as a Catalyst for Atom Transfer Radical Polymerization. Macromol. Rapid Commun. 2011, 32, 1710-1715. Link

Projects

PIRE Bio-Inspired Materials and Systems: Bruns, Nico (Principal Investigator); 01-Jan-2018 - 31-Jan-2021
Plant Inspired Materials and Surfaces (PLAMATSU) MCSA ITN: Bruns, Nico (Principal Investigator); 01-Jan-2018 - 30-Jan-2020
NCCR Bio-Inspired Materials: Bruns, Nico (Principal Investigator); 01-Jan-2018 - 30-Jan-2022

more projects

Address

Pure and Applied Chemistry
Thomas Graham Building

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