Professor Clive Wilson
Research Professor
Strathclyde Institute of Pharmacy and Biomedical Sciences
Personal statement
Clive Wilson is the J. P. Todd Professor of Pharmaceutics at Strathclyde University and serves on the European Union Federation of Pharmaceutical Sciences teaching and overseas liaison committee. He completed his Ph.D. with Professor Dennis Parke in drug metabolism at the University of Surrey. His first position was an Asthma Research Council Fellow at the Cardiothoracic Institute, London becoming a Lecturer in Biochemical Pharmacology and moving to Nottingham Medical School to become Reader in Applied Pharmacology.
Major areas of research have been the study of the behaviour of drug formulations in man. With colleagues at Nottingham, he pioneered applications of scintigraphy in the study of physiological and patho-physiological effects on drug absorption following oral, nasal, pulmonary and ophthalmic delivery. In the university, his group collaborates with industry on ophthalmic drug delivery projects especially related to the behaviour of ocular implants. He is a member of the steering group of the IMI OrBiTo programme and co-manages the Strathclyde group with Professor Gavin Halbert. Recent new areas of interest include additive soft and hard matrix technologies for drug delivery, and several programmes in novel therapies for treating ulcerative colitis.
Primary Teaching activities are in the field of Biopharmaceutics and formulation research.
Prize And Awards
- Steering Group EUFEPS
- Recipient
- 1/8/2011
- E.F.A.P.S.
- Recipient
- 15/8/2010
- F.C.R.S.
- Recipient
- 3/6/2010
- GlaxoSmithKline International Achievement Award
- Recipient
- 1/2008
Publications
- Integration of advanced methods and models to study drug absorption and related processes : an UNGAP perspective
- Wilson Clive G, Aarons Leon, Augustijns Patrick, Brouwers Joachim, Darwich Adam S, De Waal Tom, Garbacz Grzegorz, Hansmann Simone, Hoc Dagmara, Ivanova Anela, Koziolek Mirko, Reppas Christos, Schick Philipp, Vertzoni Maria, García-Horsman J Arturo
- European Journal of Pharmaceutical Sciences Vol 172 (2022)
- https://doi.org/10.1016/j.ejps.2021.106100
- Application of in vivo imaging techniques and diagnostic tools in oral drug delivery research
- Senekowitsch Stefan, Schick Philipp, Abrahamsson Bertil, Augustijns Patrick, Gießmann Thomas, Lennernäs Hans, Matthys Christophe, Marciani Luca, Pepin Xavier, Perkins Alan, Feldmüller Maximilian, Sulaiman Sarah, Weitschies Werner, Wilson Clive G, Corsetti Maura, Koziolek Mirko
- Pharmaceutics Vol 14 (2022)
- https://doi.org/10.3390/pharmaceutics14040801
- In vitro dissolution testing models of ocular implants for posterior segment drug delivery
- Adrianto Muhammad Faris, Annuryanti Febri, Wilson Clive G, Sheshala Ravi, Thakur Raghu Raj Singh
- Drug Delivery and Translational Research (2021)
- https://doi.org/10.1007/s13346-021-01043-z
- Impact of gastrointestinal tract variability on oral drug absorption and pharmacokinetics : an UNGAP review
- Vinarov Zahari, Abdallah Mohammad, Agundez José AG, Allegaert Karel, Basit Abdul W, Braeckmans Marlies, Ceulemans Jens, Corsetti Maura, Griffin Brendan T, Grimm Michael, Keszthelyi Daniel, Koziolek Mirko, Madla Christine M, Matthys Christophe, McCoubrey Laura E, Mitra Amitava, Reppas Christos, Stappaerts Jef, Steenackers Nele, Trevaskis Natalie L, Vanuytsel Tim, Vertzoni Maria, Weitschies Werner, Wilson Clive, Augustijns Patrick
- European Journal of Pharmaceutical Sciences Vol 162 (2021)
- https://doi.org/10.1016/j.ejps.2021.105812
- Current challenges and future perspectives in oral absorption research : an opinion of the UNGAP network
- Vinarov Zahari, Abrahamsson Bertil, Artursson Per, Batchelor Hannah, Berben Philippe, Bernkop-Schnürch Andreas, Butler James, Ceulemans Jens, Davies Nigel, Dupont Didier, Flaten Gøril Eide, Fotaki Nikoletta, Griffin Brendan T, Jannin Vincent, Keemink Janneke, Kesisoglou Filippos, Koziolek Mirko, Kuentz Martin, Mackie Alan, Meléndez-Martínez Antonio J, McAllister Mark, Müllertz Anette, O'Driscoll Caitriona M, Parrott Neil, Paszkowska Jadwiga, Pavek Petr, Porter Christopher JH, Reppas Christos, Stillhart Cordula, Sugano Kiyohiko, Toader Elena, Valentová Kateřina, Vertzoni Maria, De Wildt Saskia N, Wilson Clive G, Augustijns Patrick
- Advanced Drug Delivery Reviews Vol 171, pp. 289-331 (2021)
- https://doi.org/10.1016/j.addr.2021.02.001
- Multidimensional analysis of human intestinal fluid composition
- Pyper Kate, Brouwers Joachim, Augustijns Patrick, Khadra I, Dunn C, Wilson CG, Halbert GW
- European Journal of Pharmaceutics and Biopharmaceutics Vol 153, pp. 226-240 (2020)
- https://doi.org/10.1016/j.ejpb.2020.06.011
Research Interests
Steering Group, European Federation for Pharmaceutical Sciences
Professional Activities
- European Federation of Pharmaceutical Sciences (External organisation)
- Chair
- 2009
- Philips Medimetrics (External organisation)
- Advisor
- 1/2008
- 34th Controlled Release Society Conference, USA
- Keynote/plenary speaker
- 1/2008
- EUFEPS Conference on Bioavailability and Bioequivalence , Greece
- Keynote/plenary speaker
- 1/2008
- CRS Book Series Editorial Board
- Editorial board member
- 1/2008
- 10th Rotterdam Glaucoma Symposium, Netherlands
- Keynote/plenary speaker
- 1/2008
Projects
- Retinal Drug Delivery
- Khadra, Ibrahim (Principal Investigator) Wilson, Clive (Principal Investigator) Dunn, Claire (Researcher)
- The Allergan project focuses on API infused PLGA implants for ocular drug delivery. These implants are bio-degradable meaning there is no need for surgical removal of the implant. The research currently focuses on investigating the degradation of the implants at 37oC (body temperature) and 50oC (to develop an accelerated degradation model) and observing if agitation has a significant effect on degradation rate. Implants were then fully characterised to determine the physical and chemical degradation effects.
- 01-Jan-2017 - 31-Jan-2019
- EPSRC Doctoral Training Grant - DTA, University of Strathclyde | Brownlee, William John
- Seib, Philipp (Principal Investigator) Wilson, Clive (Co-investigator) Brownlee, William John (Research Co-investigator)
- 01-Jan-2015 - 11-Jan-2019
- Medical Devices Doctoral Training Centre Renewal | Hall Barrientos, Ivan
- Wilson, Clive (Principal Investigator) Black, Richard Anthony (Co-investigator) Hall Barrientos, Ivan (Research Co-investigator)
- 01-Jan-2013 - 29-Jan-2018
- ORBITO: EU Innovative Medicines Initiative In Vivo Predictive Biopharmaceutical Tools
- Halbert, Gavin (Principal Investigator) Wilson, Clive (Co-investigator)
- 01-Jan-2012 - 30-Jan-2018
- Oral Biopharmaceutics "Orbito"
- Khadra, Ibrahim (Principal Investigator) Wilson, Clive (Principal Investigator) Halbert, Gavin (Principal Investigator)
- Through partnership, collaboration and data sharing, we will develop our fundamental knowledge of the gastrointestinal environment to deliver innovative biopharmaceutics tools which will accurately predict product performance over a range of clinically relevant conditions. The integration of in vitro and in silico approaches will provide a biopharmaceutics toolkit, validated using clinical data, to accelerate drug development
- 01-Jan-2012 - 01-Jan-2019
- System Risks In Information-Rich Environments: Monitoring For Safe And Cost-Effective Operation (Bridging The Gap) / RA4511
- Marshall, Stephen (Co-investigator) Wilson, Clive (Co-investigator)
- 24-Jan-2009 - 30-Jan-2010
Contact
Professor
Clive
Wilson
Research Professor
Strathclyde Institute of Pharmacy and Biomedical Sciences
Email: c.g.wilson@strath.ac.uk
Tel: Unlisted