Professor Hannah Batchelor

Strathclyde Institute of Pharmacy and Biomedical Sciences

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Personal statement

I am currently a Professor in Pharmaceutics within the Strathclyde Institute of Pharmacy and Biomedical Sciences, University of Strathclyde, Glasgow, Scotland.

My broad research interests focus on the development of age-appropriate medicines for children. Specific research topics of interest include paediatric biopharmaceutics and development of appropriate in vitro testing strategies to predict in vivo performance; paediatric in silico modelling to optimise pharmacokinetic study design and the impact of drug-food interactions within paediatric populations. This links in silico software predictive models to better understand the mechanics of drug absorption. I am specifically interested in specialist populations (not only paediatrics) and how we can minimise the burden associated with clinical trials. This topic has generated extensive interest from large pharmaceutical companies as well as regulatory agencies and I have funding from the FDA, Janssen and Certara for ongoing projects in this space.

I am actively involved in involvement of children and young people in research, particularly clinical research that impacts upon the treatment of this population. This has led to engagement and outreach opportunities and cross-institute collaborations. I am an active member of the National Institute for Health Research (NIHR) clinical research network that involves children and young people and ensures that they are collaborators in research where possible.

I am an internationally recognised expert in the paediatric drug delivery research ranging from biopharmaceutics to acceptability assessment.

I am currently the Chair of the Academy of Pharmaceutical Sciences (www.apsgb.co.uk)

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Publications

Using mechanistic modeling approaches to support bioequivalence assessments for oral products
Wu Fang, Mousa Youssef, Jereb Rebeka, Batchelor Hannah, Chakraborty Sumon, Heimbach Tycho, Stier Ethan, Kesisoglou Filippos, Kollipara Sivacharan, Zhang Lei, Zhao Liang
AAPS Journal Vol 26 (2024)
https://doi.org/10.1208/s12248-024-00886-x
Study of in vitro poorly soluble drug solubility into fasted state simulated intestinal fluid reflective of in vivo gastrointestinal variability
McKinnon Zoe, Batchelor Hannah, Khadra Ibrahim, Halbert Gavin
British Journal of Pharmacy Vol 8 (2023)
https://doi.org/10.5920/bjpharm.1380
Quantification of drug metabolising enzymes and transporter proteins in the paediatric duodenum via LC-MS/MS proteomics using a QconCAT technique
Goelen Jan, Farrell Gillian, McGeehan Jonathan, Titman Christopher M, Rattray Nicholas JW, Johnson Trevor N, Horniblow Richard D, Batchelor Hannah K
European Journal of Pharmaceutics and Biopharmaceutics Vol 191, pp. 68-77 (2023)
https://doi.org/10.1016/j.ejpb.2023.08.011
Colour of medicines and children's acceptability? A systematic literature review of children's perceptions about colours of oral dosage forms
Alessandrini Elisa, Gonakova Milena, Batchelor Hannah, Gizurarson Sveinbjorn, Iurian Sonia, Klein Sandra, Schaufelberger Daniel, Turner Roy, Walsh Jennifer, Tuleu Catherine
Pharmaceutics Vol 15 (2023)
https://doi.org/10.3390/pharmaceutics15071992
Optimizing expert and patient input in pediatric trial design : lessons learned and recommendations from a collaboration between conect4children and European Patient‐CEntric ClinicAl TRial PLatforms
Dhaenens Britt A E, Mahler Fenna, Batchelor Hannah, Dicks Pamela, Gaillard Segolene, Nafria Begonya, Kopp‐Schneider Annette, Ribeiro Maria Alexandra, Schwab Matthias, Sparber‐Sauer Monika, Leubner Jonas, de Wildt Saskia N, Oostenbrink Rianne
Clinical and Translational Science Vol 16, pp. 1458-1468 (2023)
https://doi.org/10.1111/cts.13547
Integration of biorelevant pediatric dissolution methodology into PBPK modeling to predict in vivo performance and bioequivalence of generic drugs in pediatric populations : a carbamazepine case study
Pawar Gopal, Wu Fang, Zhao Liang, Fang Lanyan, Burckart Gilbert J, Feng Kairui, Mousa Youssef M, Al Shoyaib Abdullah, Jones Marie-Christine, Batchelor Hannah K
AAPS Journal Vol 25 (2023)
https://doi.org/10.1208/s12248-023-00826-1

More publications

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Professional Activities

Using paediatric GI data to better understand dissolution and absorption in paediatric population
Speaker
3/3/2023
Integration of biorelevant dissolution with oral PBPK to support BE evaluation for pediatric drugs
Speaker
2/3/2023
Generation and integration of paediatric gastrointestinal physiological data into PBPK software
Speaker
17/11/2022
Oral PBPK to support bioequivalence evaluation for pediatric drugs
Speaker
27/10/2022
MiniMox -Treatment for all: Developing a paediatric formulation moxidectin for neglected infectious diseases
Speaker
21/9/2022
APS PharmSci 2022
Participant
7/9/2022

More professional activities

Projects

Consultancy regarding Discovery, Product Development & Supply
Batchelor, Hannah (Principal Investigator)
30-Jan-2023 - 31-Jan-2024
GiBio Gastrointestinal bioreactor to evaluate ingestible medicines and inform formulation and manufacture (EPSRC Strategic equipment)
Batchelor, Hannah (Principal Investigator) Florence, Alastair (Co-investigator) Horan, Linda (Co-investigator) Khadra, Ibrahim (Co-investigator) McArthur, Stephen (Co-investigator)
01-Jan-2022 - 30-Jan-2025
Mechanistic understanding of the drug-colloidal structure interplay and how this may affect absorption
Batchelor, Hannah (Principal Investigator)
01-Jan-2022 - 30-Jan-2025
DTP 2224 University of Strathclyde | Abu-Rajab Tamimi, Rana
Khadra, Ibrahim (Principal Investigator) Batchelor, Hannah (Co-investigator) Abu-Rajab Tamimi, Rana (Research Co-investigator)
01-Jan-2022 - 01-Jan-2026
Industrial contribution for REA studentship: Development of simulated paediatric intestinal fluid to better predict drug absorption in children
Batchelor, Hannah (Principal Investigator)
01-Jan-2021 - 30-Jan-2024
Treatment for all: developing a paediatric formulation of moxidectin for neglected infectious diseases (MiniMox) EDCTP Research and Innovation Action
Batchelor, Hannah (Principal Investigator)
01-Jan-2021 - 30-Jan-2024

More projects

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Contact

Professor Hannah Batchelor
Strathclyde Institute of Pharmacy and Biomedical Sciences

Email: hannah.batchelor@strath.ac.uk
Tel: Unlisted

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