Professor Hannah Batchelor
Strathclyde Institute of Pharmacy and Biomedical Sciences
Personal statement
I am currently a Professor in Pharmaceutics within the Strathclyde Institute of Pharmacy and Biomedical Sciences, University of Strathclyde, Glasgow, Scotland.
My broad research interests focus on the development of age-appropriate medicines for children. Specific research topics of interest include paediatric biopharmaceutics and development of appropriate in vitro testing strategies to predict in vivo performance; paediatric in silico modelling to optimise pharmacokinetic study design and the impact of drug-food interactions within paediatric populations. This links in silico software predictive models to better understand the mechanics of drug absorption. I am specifically interested in specialist populations (not only paediatrics) and how we can minimise the burden associated with clinical trials. This topic has generated extensive interest from large pharmaceutical companies as well as regulatory agencies and I have funding from the FDA, Janssen and Certara for ongoing projects in this space.
I am actively involved in involvement of children and young people in research, particularly clinical research that impacts upon the treatment of this population. This has led to engagement and outreach opportunities and cross-institute collaborations. I am an active member of the National Institute for Health Research (NIHR) clinical research network that involves children and young people and ensures that they are collaborators in research where possible.
I am an internationally recognised expert in the paediatric drug delivery research ranging from biopharmaceutics to acceptability assessment.
I am currently the Chair of the Academy of Pharmaceutical Sciences (www.apsgb.co.uk)
Prize And Awards
- Chair of the Academy of Pharmaceutical Sciences
- Recipient
- 1/1/2022
Publications
- Using mechanistic modeling approaches to support bioequivalence assessments for oral products
- Wu Fang, Mousa Youssef, Jereb Rebeka, Batchelor Hannah, Chakraborty Sumon, Heimbach Tycho, Stier Ethan, Kesisoglou Filippos, Kollipara Sivacharan, Zhang Lei, Zhao Liang
- AAPS Journal Vol 26 (2024)
- https://doi.org/10.1208/s12248-024-00886-x
- Study of in vitro poorly soluble drug solubility into fasted state simulated intestinal fluid reflective of in vivo gastrointestinal variability
- McKinnon Zoe, Batchelor Hannah, Khadra Ibrahim, Halbert Gavin
- British Journal of Pharmacy Vol 8 (2023)
- https://doi.org/10.5920/bjpharm.1380
- Quantification of drug metabolising enzymes and transporter proteins in the paediatric duodenum via LC-MS/MS proteomics using a QconCAT technique
- Goelen Jan, Farrell Gillian, McGeehan Jonathan, Titman Christopher M, Rattray Nicholas JW, Johnson Trevor N, Horniblow Richard D, Batchelor Hannah K
- European Journal of Pharmaceutics and Biopharmaceutics Vol 191, pp. 68-77 (2023)
- https://doi.org/10.1016/j.ejpb.2023.08.011
- The pipeline for drugs for control and elimination of neglected tropical diseases : 2. Oral anti-infective drugs and drug combinations for off-label use
- Pfarr Kenneth M, Krome Anna K, Al-Obaidi Issraa, Batchelor Hannah, Vaillant Michel, Hoerauf Achim, Opoku Nicholas O, Kuesel Annette C
- Parasites and Vectors Vol 16 (2023)
- https://doi.org/10.1186/s13071-023-05909-8
- Colour of medicines and children's acceptability? A systematic literature review of children's perceptions about colours of oral dosage forms
- Alessandrini Elisa, Gonakova Milena, Batchelor Hannah, Gizurarson Sveinbjorn, Iurian Sonia, Klein Sandra, Schaufelberger Daniel, Turner Roy, Walsh Jennifer, Tuleu Catherine
- Pharmaceutics Vol 15 (2023)
- https://doi.org/10.3390/pharmaceutics15071992
- Optimizing expert and patient input in pediatric trial design : lessons learned and recommendations from a collaboration between conect4children and European Patient‐CEntric ClinicAl TRial PLatforms
- Dhaenens Britt A E, Mahler Fenna, Batchelor Hannah, Dicks Pamela, Gaillard Segolene, Nafria Begonya, Kopp‐Schneider Annette, Ribeiro Maria Alexandra, Schwab Matthias, Sparber‐Sauer Monika, Leubner Jonas, de Wildt Saskia N, Oostenbrink Rianne
- Clinical and Translational Science Vol 16, pp. 1458-1468 (2023)
- https://doi.org/10.1111/cts.13547
Professional Activities
- Using paediatric GI data to better understand dissolution and absorption in paediatric population
- Speaker
- 3/3/2023
- Integration of biorelevant dissolution with oral PBPK to support BE evaluation for pediatric drugs
- Speaker
- 2/3/2023
- Generation and integration of paediatric gastrointestinal physiological data into PBPK software
- Speaker
- 17/11/2022
- Oral PBPK to support bioequivalence evaluation for pediatric drugs
- Speaker
- 27/10/2022
- MiniMox -Treatment for all: Developing a paediatric formulation moxidectin for neglected infectious diseases
- Speaker
- 21/9/2022
- APS PharmSci 2022
- Participant
- 7/9/2022
Projects
- Consultancy regarding Discovery, Product Development & Supply
- Batchelor, Hannah (Principal Investigator)
- 30-Jan-2023 - 31-Jan-2024
- GiBio Gastrointestinal bioreactor to evaluate ingestible medicines and inform formulation and manufacture (EPSRC Strategic equipment)
- Batchelor, Hannah (Principal Investigator) Florence, Alastair (Co-investigator) Horan, Linda (Co-investigator) Khadra, Ibrahim (Co-investigator) McArthur, Stephen (Co-investigator)
- 01-Jan-2022 - 30-Jan-2025
- Mechanistic understanding of the drug-colloidal structure interplay and how this may affect absorption
- Batchelor, Hannah (Principal Investigator)
- 01-Jan-2022 - 30-Jan-2025
- DTP 2224 University of Strathclyde | Abu-Rajab Tamimi, Rana
- Khadra, Ibrahim (Principal Investigator) Batchelor, Hannah (Co-investigator) Abu-Rajab Tamimi, Rana (Research Co-investigator)
- 01-Jan-2022 - 01-Jan-2026
- Industrial contribution for REA studentship: Development of simulated paediatric intestinal fluid to better predict drug absorption in children
- Batchelor, Hannah (Principal Investigator)
- 01-Jan-2021 - 30-Jan-2024
- Treatment for all: developing a paediatric formulation of moxidectin for neglected infectious diseases (MiniMox) EDCTP Research and Innovation Action
- Batchelor, Hannah (Principal Investigator)
- 01-Jan-2021 - 30-Jan-2024
Contact
Professor
Hannah
Batchelor
Strathclyde Institute of Pharmacy and Biomedical Sciences
Email: hannah.batchelor@strath.ac.uk
Tel: Unlisted