Dr Rebecca Beveridge
Senior Lecturer
Pure and Applied Chemistry
Personal statement
Rebecca is a Senior Lecturer and UKRI Future Leaders Fellow who joined the University of Strathclyde in June 2020 as a Chancellor's Fellow. She obtained a BSc in biochemistry and chemistry from the University of Leeds in 2011 and completed her PhD at the University of Manchester in 2015. Rebecca spent 4 years at the Institute for Molecular Pathology in Vienna, Austria as a postdoctoral researcher/ Lise Meitner Postdoctoral Fellow. Throughout her career, she has collected experience in a plethora of mass spectrometry methods to study protein structure such as native mass spectrometry, ion mobility, hydrogen-deuterium exchange, and crosslinking.
Rebecca’s current research is centered around the development of native ion mobility mass spectrometry methods to study proteins and protein complexes, particularly those that are challenging to study with conventional biochemistry methods. Such systems include intrinsically disordered proteins that exist in a wide range of different shapes, and protein complexes formed by protein-degrading molecules such as PROTACs, the complex binding modes of which are challenging to delineate.
Publications
- Ion mobility mass spectrometry unveils conformational effects of drug lead EPI-001 on the intrinsically disordered N-terminal domain of the Androgen Receptor
- Ahmed Ikhlas M M, Rofe Adam, Henry Martyn C, West Eric, Jamieson Craig, McEwan Iain J, Beveridge Rebecca
- Protein Science Vol 34 (2025)
- https://doi.org/10.1002/pro.5254
- S-MGBs bearing amidine tail groups are potent, selective antiplasmodial agents
- Perieteanu Marina, Rodriguez Garzon Tayner, McGee Leah M C, Khalaf Abedawn I, Suckling Colin J, Beveridge Rebecca, Avery Vicky M, Scott Fraser J
- RSC Medicinal Chemistry (2024)
- https://doi.org/10.1039/D4MD00619D
- Strathclyde Minor Groove Binders (S-MGBs) with activity against Acanthamoeba castellanii
- McGee Leah MC, Carpinteyro Sanchez Alemao G, Perieteanu Marina, Eskandari Kaveh, Bian Yan, Mackie Logan, Young Louise, Beveridge Rebecca, Suckling Colin J, Roberts Craig W, Scott Fraser J
- Journal of Antimicrobial Chemotherapy Vol 79, pp. 2251-2258 (2024)
- https://doi.org/10.1093/jac/dkae221
- Amorphous aggregates with a very wide size distribution play a central role in crystal nucleation
- Liao Zhiyu, Das Ankita, Robb Christina Glen, Beveridge Rebecca, Wynne Klaas
- Chemical Science Vol 15, pp. 12420-12430 (2024)
- https://doi.org/10.1039/D4SC00452C
- Rapid flow-based synthesis of post-translationally modified peptides and proteins : a case study on MYC's transactivation domain
- Williams Elyse T, Schiefelbein Kevin, Schuster Matthias, Ahmed Ikhlas M M, De vries Marije, Beveridge Rebecca, Zerbe Oliver, Hartrampf Nina
- Chemical Science Vol 15, pp. 8756-8765 (2024)
- https://doi.org/10.1039/D4SC00481G
- Exploiting bi-specific engagement : assessing monovalent vs bivalent binding
- Duxbury Rachel, Beveridge Rebecca, Jamieson Craig, Jones David, Jones Gavin, Rattray Zahra
- Immuno-oncology Summit Europe 2024 (2024)
Professional Activities
- Ion mobility mass spectrometry analysis of dynamic proteins and protein complexes
- Speaker
- 11/1/2024
- Nature Communications (Journal)
- Peer reviewer
- 1/1/2024
- Ion mobility mass spectrometry analysis of dynamic proteins and protein complexes
- Speaker
- 21/11/2023
- Introduction to native mass spectroemtry
- Speaker
- 9/11/2023
- Ion mobility mass spectrometry analysis of dynamic proteins and protein complexes
- Speaker
- 7/11/2023
- Ion mobility mass spectrometry insights into dynamic protein complexes and conformations
- Speaker
- 3/11/2023
Projects
- Understanding intrinsically disordered proteins and their potential as new drug (FLF renewal)
- Beveridge, Rebecca (Principal Investigator)
- 01-Jan-2024 - 31-Jan-2027
- DTP 2224 University of Strathclyde | Madoda, Mxolisi
- Beveridge, Rebecca (Principal Investigator) Chow, Shiao (Co-investigator) Madoda, Mxolisi (Research Co-investigator)
- 01-Jan-2023 - 01-Jan-2027
- Intact protein mass measurement
- Beveridge, Rebecca (Principal Investigator)
- 01-Jan-2023 - 31-Jan-2024
- Understanding the relationship between target affinities of bi-specific antibodies to dual cell-membrane targets and their impact on cell binding and selectivity to improve the accuracy and value of in silico modelling for prediction of the optimal target affinities for effective clinical outcomes
- Rattray, Zahra (Principal Investigator) Beveridge, Rebecca (Principal Investigator) Duxbury, Rachel (Post Grad Student)
- 01-Jan-2022 - 31-Jan-2026
- Industrial CASE Account - University of Strathclyde 2022 | Jackson, Cara
- Beveridge, Rebecca (Principal Investigator) Jamieson, Craig (Co-investigator) Jackson, Cara (Research Co-investigator)
- 01-Jan-2022 - 01-Jan-2026
- Development of innovative label-free methods to investigate the binding properties and degradation efficiencies of PROTACs
- Beveridge, Rebecca (Principal Investigator)
- 01-Jan-2022 - 30-Jan-2026
Contact
Dr
Rebecca
Beveridge
Senior Lecturer
Pure and Applied Chemistry
Email: rebecca.beveridge@strath.ac.uk
Tel: Unlisted