Dr Yu Chen

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Physics

Personal statement

Dr. Yu Chen received her PhD from Birmingham University in nanoscale physics in 2000 and subsequently was appointed to a lectureship in molecular nanometrology at Strathclyde University in 2007 funded by an EPSRC Science and Innovation Award. She is a fellow of the Royal Microscopical Society, a member of the European Microscopy Society, the Institute of Physics, the American Chemical Society, and the Nanotechnology Knowledge Transfer Network. She serves as an expert panel member for the European Cooperation in Science and Technology, a referee for top international journals, an invited speaker and a committee member for a number of international conferences and workshops.

Dr Chen’s main research activities lie in the creation and characterization of nanoscale structures for their unique physical and chemical properties, utilizing both optical and electron microscopy and spectroscopy. Her recent research in Photophysics Group focuses on surface plasmon enhanced effect, including two-photon luminescence, energy transfer and SERRS from noble metal nanoparticles, arrays and porous media, with strong links to biomedical imaging and sensing, as well as nanoparticle-cell interaction and cytotoxicity. Other work includes 3D visualization of nanoparticles, stability of Au nanoparticles, and creating nanostructures using chemical lithography and direct writing.

Publications

Morphological changes of silica shells deposited on gold nanorods : implications for nanoscale photocatalysts
Adelt Milan, MacLaren Donald A, Birch David J S, Chen Yu
ACS Applied Nano Materials (2021)
https://doi.org/10.1021/acsanm.1c00977
One-dimensional deep learning architecture for fast fluorescence lifetime imaging
Xiao Dong, Chen Yu, Li David Day-Uei
IEEE Journal of Selected Topics in Quantum Electronics Vol 27 (2021)
https://doi.org/10.1109/JSTQE.2021.3049349
Histogram clustering for rapid time-domain fluorescence lifetime image analysis
Li Yahui, Sapermsap Natakorn, Yu Jun, Tian Jinshou, Chen Yu, Li David Day-Uei
Biomedical Optics Express (2021)
Dynamic fluorescence lifetime sensing with CMOS single-photon avalanche diode arrays and deep learning processors
Xiao Dong, Zang Zhenya, Sapermsap Natakorn, Wang Quan, Xie Wujun, Chen Yu, Li David Day Uei
Biomedical Optics Express Vol 12, pp. 3450-3462 (2021)
https://doi.org/10.1364/BOE.425663
On synthetic instrument response functions of time-correlated single-photon counting based fluorescence lifetime imaging analysis
Xiao Dong, Sapermsap Natakorn, Safar Mohammed, Cunningham Margaret Rose, Chen Yu, Li David Day-Uei
Frontiers in Physics Vol 9 (2021)
https://doi.org/10.3389/fphy.2021.635645
Investigations on average fluorescence lifetimes for visualizing multi-exponential decays
Li Yahui, Natakorn Sapermsap, Chen Yu, Safar Mohammed, Cunningham Margaret, Tian Jinshou, Li David Day-Uei
Frontiers in Physics Vol 8 (2020)
https://doi.org/10.3389/fphy.2020.576862

More publications

Professional activities

5th international conference on bioinformatics and miomedical engineering
Organiser
2011
Invited editor for a book to the Nanoscience and Nanotechnology Book Series published by the Royal Society of Chemistry
Guest editor
2011
International Communication Association Annual Conference 2014
Invited speaker
2010
European Cooperation in Science and Technology (External organisation)
Advisor
2010
Expert in Round Table Group, Washington, DC, USA
Advisor
2010
FluoroFest
Invited speaker
2010

More professional activities

Projects

SPRINT: A SuPer-Resolution time-resolved ImagiNg and specTroscopy facility for rapid biomolecular analysis
Li, David (Principal Investigator) Chamberlain, Luke (Co-investigator) Chen, Yu (Co-investigator) Cunningham, Margaret Rose (Co-investigator) Gould, Gwyn (Co-investigator) Hoskisson, Paul (Co-investigator) McConnell, Gail (Co-investigator) Rattray, Zahra (Co-investigator) Van de Linde, Sebastian (Co-investigator)
01-Jan-2021 - 30-Jan-2022
A new tool for rapid RNA detection in single cells_pathfinder
Chen, Yu (Principal Investigator)
08-Jan-2019 - 07-Jan-2019
Smart flow cytometry for cancer diagnosis using silicon single-photon sensors and nanoprobes
Li, David (Principal Investigator) Chen, Yu (Research Co-investigator) Xiao, Dong (Researcher)
01-Jan-2018 - 30-Jan-2022
Doctoral Training Partnership (DTP 2016-2017 University of Strathclyde) | Adelt, Milan
Chen, Yu (Principal Investigator) Birch, David (Co-investigator) Adelt, Milan (Research Co-investigator)
01-Jan-2017 - 01-Jan-2021
New Application of a DNA-nanorod Platform for Vaccine Development
Yu, Jun (Principal Investigator) Chen, Yu (Co-investigator) Roberts, Craig (Co-investigator)
A Novel DNA-nanorod platform for diverse Chemeric viral Vaccine Development Stream 1 - Scientific and Technical Feasibility
01-Jan-2017 - 30-Jan-2018
Fluorescent mRNA nanoprobes for rapid cancer detection: Application to single cells and clinical trials
Chen, Yu (Principal Investigator)
01-Jan-2017 - 31-Jan-2020

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