Dr Yu Chen

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Physics

Personal statement

Dr. Yu Chen received her PhD from Birmingham University in nanoscale physics in 2000 and subsequently was appointed to a lectureship in molecular nanometrology at Strathclyde University in 2007 funded by an EPSRC Science and Innovation Award. She is a fellow of the Royal Microscopical Society, a member of the European Microscopy Society, the Institute of Physics, the American Chemical Society, and the Nanotechnology Knowledge Transfer Network. She serves as an expert panel member for the European Cooperation in Science and Technology, a referee for top international journals, an invited speaker and a committee member for a number of international conferences and workshops.

Dr Chen’s main research activities lie in the creation and characterization of nanoscale structures for their unique physical and chemical properties, utilizing both optical and electron microscopy and spectroscopy. Her recent research in Photophysics Group focuses on surface plasmon enhanced effect, including two-photon luminescence, energy transfer and SERRS from noble metal nanoparticles, arrays and porous media, with strong links to biomedical imaging and sensing, as well as nanoparticle-cell interaction and cytotoxicity. Other work includes 3D visualization of nanoparticles, stability of Au nanoparticles, and creating nanostructures using chemical lithography and direct writing.

Prizes and awards

Member of the European Microscopy Society; Member of the Institute of Physics,; Member of the American Chemical Society.; Member of Society of Chemical Industry; Member of Nanotechnology Knowledge Transfer Network.: Recipient; 2007
A Fellow of the Royal Microscopical Society: Recipient; 2007

more prizes and awards

Publications

Lysozyme encapsulated gold nanoclusters for probing the early stage of lysozyme aggregation under acidic conditions: Alkudaisi Nora, Russell Ben Allan, Birch David J S, Chen Yu; Journal of Photochemistry and Photobiology B: Biology Vol 197 (2019); https://doi.org/10.1016/j.jphotobiol.2019.111540
Synthesis of small gold nanorods and their subsequent functionalization with hairpin single stranded DNA: Mbalaha Zendesha S, Edwards Paul R, Birch David JS, Chen Yu; ACS Omega Vol 4, pp. 13740-13746 (2019); https://doi.org/10.1021/acsomega.9b01200
Critical role of tyrosine-20 in formation of gold nanoclusters within lysozyme : a molecular dynamics study: Russell Ben A, Kubiak-Ossowska Karina, Chen Yu, Mulheran Paul A; Physical Chemistry Chemical Physics Vol 21, pp. 4907-4911 (2019); https://doi.org/10.1039/C8CP06374E
Detecting Lysozyme unfolding via the fluorescence of Lysozyme encapsulated gold nanoclusters: Alkudaisi Nora, Russell Ben A, Jachimska Barbara, Birch David J S, Chen Yu; Journal of Materials Chemistry B, pp. 1-10 (2019)
Polyallylamine hydrochloride coating enhances the fluorescence emission of human serum albumin encapsulated gold nanoclusters: Russell Ben Allan, Jachimska Barbara, Chen Yu; Journal of Photochemistry and Photobiology B: Biology Vol 187, pp. 131-135 (2018); https://doi.org/10.1016/j.jphotobiol.2018.08.018
Sudlow site II of human serum albumin remains functional after gold nanocluster encapsulation : a fluorescence-based drug binding study of L-Dopa: Russell Ben A, Garton Ashley, Alshammari Abeer Saeed, Birch David J S, Chen Yu; Methods and Applications in Fluorescence Vol 6 (2018); https://doi.org/10.1088/2050-6120/aacdee

more publications

Professional activities

Invited editor for a book to the Nanoscience and Nanotechnology Book Series published by the Royal Society of Chemistry: Guest editor; 2011
5th international conference on bioinformatics and miomedical engineering: Organiser; 2011
International Communication Association Annual Conference 2014: Invited speaker; 2010
Expert in Round Table Group, Washington, DC, USA: Advisor; 2010
European Cooperation in Science and Technology (External organisation): Advisor; 2010
FluoroFest: Invited speaker; 2010

more professional activities

Projects

A new tool for rapid RNA detection in single cells_pathfinder: Chen, Yu (Principal Investigator); 08-Jan-2019 - 07-Jan-2019
Smart flow cytometry for cancer diagnosis using silicon single-photon sensors and nanoprobes: Li, David (Principal Investigator) Chen, Yu (Research Co-investigator) Xiao, Dong (Researcher); 01-Jan-2018 - 30-Jan-2022
Doctoral Training Partnership (DTP 2016-2017 University of Strathclyde) | Adelt, Milan: Chen, Yu (Principal Investigator) Birch, David (Co-investigator) Adelt, Milan (Research Co-investigator); 01-Jan-2017 - 01-Jan-2021
New Application of a DNA-nanorod Platform for Vaccine Development: Yu, Jun (Principal Investigator) Chen, Yu (Co-investigator) Roberts, Craig (Co-investigator); 01-Jan-2017 - 30-Jan-2018
Fluorescent mRNA nanoprobes for rapid cancer detection: Application to single cells and clinical trials: Chen, Yu (Principal Investigator); 01-Jan-2017 - 31-Jan-2020
Nanoprobes for melanin and melanoma (support for CDT in Medical Imaging): Birch, David (Principal Investigator) Chen, Yu (Co-investigator) Sutter, Jens (Co-investigator); 01-Jan-2014 - 30-Jan-2018

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Address

Physics
John Anderson Building

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