Dr Yu Chen

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Physics

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Personal statement

Dr. Yu Chen received her PhD from Birmingham University in nanoscale physics in 2000 and subsequently was appointed to a lectureship in molecular nanometrology at Strathclyde University in 2007 funded by an EPSRC Science and Innovation Award. She is a fellow of the Royal Microscopical Society, a member of the European Microscopy Society, the Institute of Physics, the American Chemical Society, and the Nanotechnology Knowledge Transfer Network. She serves as an expert panel member for the European Cooperation in Science and Technology, a referee for top international journals, an invited speaker and a committee member for a number of international conferences and workshops.

Dr Chen’s main research activities lie in the creation and characterization of nanoscale structures for their unique physical and chemical properties, utilizing both optical and electron microscopy and spectroscopy. Her recent research in Photophysics Group focuses on surface plasmon enhanced effect, including two-photon luminescence, energy transfer and SERRS from noble metal nanoparticles, arrays and porous media, with strong links to biomedical imaging and sensing, as well as nanoparticle-cell interaction and cytotoxicity. Other work includes 3D visualization of nanoparticles, stability of Au nanoparticles, and creating nanostructures using chemical lithography and direct writing.

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Publications

Dendrimer platforms for targeted doxorubicin delivery : physicochemical properties in context of biological responses
Szota Magdalena, Szwedowicz Urszula, Rembialkowska Nina, Janicka-Klos Anna, Doveiko Daniel, Chen Yu, Kulbacka Julita, Jachimska Barbara
International Journal of Molecular Sciences Vol 25 (2024)
https://doi.org/10.3390/ijms25137201
Smartphone-based optical sectioning (SOS) microscopy with a telecentric design for fluorescence imaging
Jiao Ziao, Pan Mingliang, Yousaf Khadija, Doveiko Daniel, Maclean Michelle, Griffin David, Chen Yu, Li David Day Uei
Journal of Microscopy (2024)
https://doi.org/10.1111/jmi.13334
Estimating binding energies of π-stacked aromatic dimers using force field-driven molecular dynamics
Doveiko Daniel, Kubiak-Ossowska Karina, Chen Yu
International Journal of Molecular Sciences Vol 25 (2024)
https://doi.org/10.3390/ijms25115783
Impact of the crystal structure of silica nanoparticles on Rhodamine 6G adsorption
Doveiko Daniel, Kubiak-Ossowska Karina, Chen Yu
67th International Open Readings Conference for students of Physics and Natural Sciences. Annual Abstract Book 2024 67th International Conference for Students of Physics and Natural Sciences ‘Open
Readings 2024’, pp. 91-91 (2024)
https://doi.org/10.15388/Proceedings.2024.46
Aptamer functionalised small gold nanorod-based nanoprobes : targeting EpCAM over-expressed cancer cells for photothermal therapy
Mbalaha ZS, Craig G, Birch DJS, Chen Y
Austin Journal of Analytical & Pharmaceutical Chemistry Vol 11 (2024)
Nanoparticle metrology of silicates using time-resolved multiplexed dye fluorescence anisotropy
Doveiko Daniel, Martin Alan RG, Vyshemirsky Vladislav, Stebbing Simon, Kubiak-Ossowska Karina, Rolinski Olaf, Birch David JS, Chen Yu
PCCP 25th Anniversary Symposium (2024)

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Professional Activities

5th international conference on bioinformatics and miomedical engineering
Organiser
2011
Invited editor for a book to the Nanoscience and Nanotechnology Book Series published by the Royal Society of Chemistry
Guest editor
2011
International Communication Association Annual Conference 2014
Invited speaker
2010
Expert in Round Table Group, Washington, DC, USA
Advisor
2010
European Cooperation in Science and Technology (External organisation)
Advisor
2010
FluoroFest
Invited speaker
2010

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Projects

Investigating the potential toxicity and immunomodulatory properties of lysozyme-encapsulated nanoclusters in primary cell cultures using a 2D triple culture model of Alzheimer’s disease (Holly Brown)
Jiang, Hui-Rong (Principal Investigator) Chen, Yu (Co-investigator)
01-Jan-2023 - 30-Jan-2024
Lysozyme encapsulated gold nanoclusters – a new therapeutic agent for Alzheimer’s disease
Jiang, Hui-Rong (Principal Investigator) Chen, Yu (Co-investigator) Sakata, Shuzo (Co-investigator)
01-Jan-2022 - 30-Jan-2025
EPSRC IAA: Time-resolved flow cytometry and cell sorter: Application to liquid biopsy for cancer detection
Chen, Yu (Co-investigator)
01-Jan-2022 - 31-Jan-2026
Efficient optical spectroscopy techniques for biosensing
Li, David (Principal Investigator) Chen, Xi (Researcher) Chen, Yu (Co-investigator)
01-Jan-2021 - 30-Jan-2024
Fluorescence imaging characterisation of silicates
Chen, Yu (Principal Investigator) Rolinski, Olaf (Co-investigator)
01-Jan-2021 - 31-Jan-2025
Doctoral Training Partnership 2020-2021 University of Strathclyde | Doveiko, Daniel
Chen, Yu (Principal Investigator) Chen, Yu (Co-investigator) Doveiko, Daniel (Research Co-investigator)
01-Jan-2021 - 01-Jan-2025

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Contact

Dr Yu Chen
Reader
Physics

Email: y.chen@strath.ac.uk
Tel: 548 3087