Save this page
Save this page

My Saved Pages

  • Saved page.

My Saved Courses

  • Saved page.
Reset

Recently visited

  • Saved page.

Dr RuAngelie Edrada-Ebel

Senior Lecturer

Strathclyde Institute of Pharmacy and Biomedical Sciences

Personal statement

Dr Edrada-Ebel currently heads the Natural Products Metabolomics Group (NPMG) and is currently author of more than 100 publications and two patents on the topic marine natural products. She referees articles on marine natural products on more than 10 peer-reviewed journals and is a member of the editorial board for Marine Drugs. Her expertise comprises both natural products isolation and structure elucidation with modern spectroscopic techniques. At present, she has a series of on-going projects on the application of metabolomics to identify and biotechnologically optimize the production of bioactive secondary metabolites in marine-derived microorganisms.

Publications

Green tea inhibits uterine contractility in ex vivo (non-pregnant) mice models
Bafor Enitome E., Eze Chioma, Omoruyi Osemelomen , Elvis-Offiah Beauty U. , Viegelmann Christina, Edrada-Ebel RuAngelie
Tropical Journal of Natural Product Research Vol 2, pp. 254-261, (2018)
http://dx.doi.org/10.26538/tjnpr/v2i6.1
Modulation of ex-vivo uterine contraction by the methanol leaf extract of Alchornea laxiflora Benth. (Euphorbiaceae) and preliminary spectrometric identification of associated secondary metabolites
Bafor Enitome E., Nwogu Juliet K. , Elvis-Offiah Uloma B., Amaechina Fabian , Ofeimun Josephine , Ayinde Buniyamin , Omoruyi Osemelomen , Viegelmann Christina, Edrada-Ebel RuAngelie
Journal of Medicinal Plants For Economic Development Vol 2, (2018)
http://dx.doi.org/10.4102/jomped.v2i1.33
Metabolomics-coupled functional pharmacology of chlorophyll compounds isolated from the leaves of Ficus Exasperata Vahl (Moraceae) provides novel pathways on myometrial activity
Bafor Enitome E., Rowan Edward G., Edrada-Ebel RuAngelie
Reproductive Sciences Vol 25, pp. 923-937, (2018)
http://dx.doi.org/10.1177/1933719117732159
SeaBioTech : from seabed to test-bed: harvesting the potential of marine biodiversity for industrial biotechnology
Edrada-Ebel RuAngelie, Ævarsson Arnthor , Polymenakou Paraskevi , Hentschel Ute , Carettoni Daniele , Day John, Green David, Hreggviðsson Guðmundur Óli , Harvey Linda, McNeil Brian
Grand Challenges in Marine BiotechnologyGrand Challenges in Biology and Biotechnology, (2018)
http://dx.doi.org/10.1007/978-3-319-69075-9_12
Bioactive pyrrole alkaloids isolated from the Red Sea : marine sponge Stylissa carteri
Hamed Ashraf N. E., Schmitz Roland, Bergermann Anja, Totzke Frank, Kubbutat Michael, Müller Werner E. G., Youssef Diaa T.A., Bishr Mokhtar M., Kamel Mohamed S., Edrada-Ebel RuAngelie, Wätjen Wim, Proksch Peter
Zeitschrift fur Naturforschung - Section C Journal of Biosciences Vol 73, pp. 199-210, (2018)
http://dx.doi.org/10.1515/znc-2017-0161
Metabolomic-guided isolation of bioactive natural products from Curvularia sp., an endophytic fungus of Terminalia laxiflora
Tawfike Ahmed F., Abbott Grainne, Young Louise, Edrada-Ebel Ruangelie
Planta Medica Vol 84, pp. 182-190, (2018)
http://dx.doi.org/10.1055/s-0043-118807

more publications

Research interests

  • Natural products metabolomics to optimise production of secondary metabolites in their microbial sources as well as using metabolomics tools in targeting the isolation of bioactive metabolites from their natural sources. Collaboration has been established with Professor Ron Quinn of the Griffith Institute for Drug Discovery, Griffith University and Professor  Fernando da Costa of the School of Pharmaceutical Sciences of Ribeirão Preto, University of São Paulo.
  • Metabolomics of microbial symbionts in collaboration with Professor Ute Hentschel of the Sponge Microbiology Group at the GEOMAR Helmholtz Centre for Ocean Research Kiel and partners with SeaBioTech, an FP-7 funded project.
  • Real Time Flux Modeling in Biopharmaceutical Bioprocessing, jointly co-funded by the BBSRC and the EPSRC, a collaborative research on metabolomics and fermentation work as well as further national collaborative work with Scottish medium-scale enterprises on the cultivation of marine microorganism. 
  • Metagenomic approach of optimizing the production of novel antibiotics from Streptomyces
  • Propolis project with Beevital exploring the anti-trypanosomal activity of the African Propolis collection
  • Ecological implications of the production of secondary metabolites in Crustaeceans and alternative application of utilising the waste products of the by-catch in collaboration with the Langoustine Laboratory, University of Glasgow.
  • Dereplication study and metabolomics of sponges and their endozooic microorganism obtained from the Irish and Celtic Sea (in collaboration with Prof. Alan Dobson, Environmental Research Institute, University College Cork)
  • Structure elucidation of biologically active secondary metabolites from sponges, tropical plants, and marine-derived fungi
  • Phytochemistry of biologically active secondary metabolites from tropical plants from Southeast Asia and Africa (in collaboration with Prof. Alan Harvey, SIDR)
  • Mass spectral analysis of marine-derived synthetic pyridinium polymers as novel anti-cancer drugs (in collaboration with Prof. Marcel Jaspars, University of Aberdeen)

Professional activities

Dr Asmaa BOUFRIDI
Host
6/7/2018
Jake Coyle
Host
2/7/2018
Accelerate Chemistry Challenge Programme for Secondary Schools in Scotland: S@S Accelerate 2018: Education Challenge
Invited speaker
27/6/2018
AHMET SADIK GÜLGEÇ
Host
15/6/2018
Euroindoamerican Natural Products Meeting
Keynote/plenary speaker
31/5/2018
A course on Searching Active compounds from Marine Organisms
Invited speaker
24/5/2018

more professional activities

Projects

Development of high-value compounds from Bacillus licheniformis
Edrada-Ebel, Ruangelie (Principal Investigator) Young, Louise (Co-investigator)
Period 01-Nov-2017 - 28-Feb-2018
Identification of pathway specific anti-cancer compounds from Scottish Marine Microbes
Edrada-Ebel, Ruangelie (Principal Investigator)
This agreement is applicable to only the original MATERIAL for the analyses of chemical contents of a series of research materials originating from Scotland.
Period 29-Nov-2016 - 28-Nov-2018
Potential novel antibiotics from microorganisms of under explored extreme marine habitats
Edrada-Ebel, Ruangelie (Principal Investigator)
Period 25-Jul-2016 - 24-Sep-2016
Escaping Bio-Assay Guided Isolation: Nature's Tools for Chemical Biology
Edrada-Ebel, Ruangelie (Principal Investigator)
Period 01-Sep-2015 - 31-Aug-2018
Comparative transcriptomic and metabolomic analysis of engineered bacteria
Tucker, Nicholas (Principal Investigator) Edrada-Ebel, Ruangelie (Co-investigator)
Analysis of industrial biotech strains produced by Ingenza
Period 18-Nov-2014 - 18-Nov-2015
Grace Reveleris Flash LSD
Edrada-Ebel, Ruangelie (Academic) Watson, David (Academic)
Period 01-Sep-2012

more projects

Address

Strathclyde Institute of Pharmacy and Biomedical Sciences
Hamnett Wing John Arbuthnott Building

Location Map

View University of Strathclyde in a larger map