Dr RuAngelie Edrada-Ebel
Senior Lecturer
Strathclyde Institute of Pharmacy and Biomedical Sciences
Personal statement
Dr Edrada-Ebel currently heads the Natural Products Metabolomics Group (NPMG) and is currently author of more than 100 publications and two patents on the topic marine natural products. She referees articles on marine natural products on more than 10 peer-reviewed journals and is a member of the editorial board for Marine Drugs. Her expertise comprises both natural products isolation and structure elucidation with modern spectroscopic techniques. At present, she has a series of on-going projects on the application of metabolomics to identify and biotechnologically optimize the production of bioactive secondary metabolites in marine-derived microorganisms.
Prize And Awards
Qualifications
Positions Held:
2015 to date Senior Lecturer in Pharmaceutical Analysis, Strathclyde Institute of Pharmacy and Biomedical Sciences
2008 to 2014 Lecturer in Pharmaceutical Analysis, Strathclyde Institute of Pharmacy and Biomedical Sciences
2007 to 2008 NMR and MS Facility Manager, Strathclyde Institute of Pharmacy and Biomedical Sciences
2005 to 2007 Research Scientist (part-time), BioMar, Düsseldorf Life Science Centre
2001 to 2007 Senior Researcher and Instructor, Institute of Pharmaceutical Biology and Biotechnology, Heinrich-Heine Universität Düsseldorf
1999 to 2001 Research Fellow (Post Doctorate), Department of Chemistry, University of California Santa Cruz
1998 to 1999 Research Fellow, Department of Chemistry and Biochemistry, University of Oklahoma
1989 to 1993 Instructor, College of Pharmacy, University of the Philippines
Educational Background:
1994 – 1998 Doctorate degree in Pharmaceutical Biology, Julius Maximillians-University of Würzburg, Germany, Magna cum Laude, Dissertation: “Isolation and structure elucidation of bioactive secondary metabolites from Philippine marine sponges and soft corals.” Adviser: Prof. Dr. Peter Proksch, Date of Graduation: 18 June 1998
1989 - 1992 Master of Science degree in Pharmacy, University of the Philippines, Manila, Philippines, Thesis: “The biological and chemical investigation of the colored constituents of Kokoona ochracea (Elm) Merrill (Fam. Celastraceae).”
Publications
Research Interests
- Natural products metabolomics to optimise production of secondary metabolites in their microbial sources as well as using metabolomics tools in targeting the isolation of bioactive metabolites from their natural sources. Collaboration has been established with Professor Ron Quinn of the Griffith Institute for Drug Discovery, Griffith University and Professor Fernando da Costa of the School of Pharmaceutical Sciences of Ribeirão Preto, University of São Paulo.
- Metabolomics of microbial symbionts in collaboration with Professor Ute Hentschel of the Sponge Microbiology Group at the GEOMAR Helmholtz Centre for Ocean Research Kiel and partners with SeaBioTech, an FP-7 funded project.
- Real Time Flux Modeling in Biopharmaceutical Bioprocessing, jointly co-funded by the BBSRC and the EPSRC, a collaborative research on metabolomics and fermentation work as well as further national collaborative work with Scottish medium-scale enterprises on the cultivation of marine microorganism.
- Metagenomic approach of optimizing the production of novel antibiotics from Streptomyces
- Propolis project with Beevital exploring the anti-trypanosomal activity of the African Propolis collection
- Ecological implications of the production of secondary metabolites in Crustaeceans and alternative application of utilising the waste products of the by-catch in collaboration with the Langoustine Laboratory, University of Glasgow.
- Dereplication study and metabolomics of sponges and their endozooic microorganism obtained from the Irish and Celtic Sea (in collaboration with Prof. Alan Dobson, Environmental Research Institute, University College Cork)
- Structure elucidation of biologically active secondary metabolites from sponges, tropical plants, and marine-derived fungi
- Phytochemistry of biologically active secondary metabolites from tropical plants from Southeast Asia and Africa (in collaboration with Prof. Alan Harvey, SIDR)
- Mass spectral analysis of marine-derived synthetic pyridinium polymers as novel anti-cancer drugs (in collaboration with Prof. Marcel Jaspars, University of Aberdeen)
Professional Activities
Projects
Contact
Dr
RuAngelie
Edrada-Ebel
Senior Lecturer
Strathclyde Institute of Pharmacy and Biomedical Sciences
Email: ruangelie.edrada-ebel@strath.ac.uk
Tel: 548 5968