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Professor Karen Faulds

Pure and Applied Chemistry

Publications

Tracking intracellular uptake and localisation of alkyne tagged fatty acids using Raman spectroscopy
Jamieson Lauren E., Greaves Jennifer, McLellan Jayde A., Munro Kevin R., Tomkinson Nicholas C.O., Chamberlain Luke H., Faulds Karen, Graham Duncan
Spectrochimica Acta - Part A: Molecular and Biomolecular Spectroscopy Vol 197, pp. 30-36, (2018)
http://dx.doi.org/10.1016/j.saa.2018.01.064
Introducing 12 new dyes for use with oligonucleotide functionalised silver nanoparticles for DNA detection with SERS
Pala L., Mabbott S., Faulds K., Bedics M. A., Detty M. R., Graham D.
RSC Advances Vol 2018, pp. 17685-17693, (2018)
http://dx.doi.org/10.1039/C8RA01998C
Through tissue imaging of a live breast cancer tumour model using handheld surface enhanced spatially offset resonance Raman spectroscopy (SESORRS)
Nicolson Fay, Jamieson Lauren E., Mabbott Samuel, Plakas Konstantinos, Shand Neil C., Detty Michael R., Graham Duncan, Faulds Karen
Chemical Science Vol 9, pp. 3788-3792, (2018)
http://dx.doi.org/10.1039/c8sc00994e
Through tissue imaging of a live breast cancer tumour model using handheld surface enhanced spatially offset Resonance Raman Spectroscopy
Nicolson Fay, Jamieson Lauren E, Mabbott Samuel, Plakas Konstantinos, Shand Neil, Detty Michael, Graham Duncan, Faulds Karen
Chemical Science, (2018)
http://dx.doi.org/10.1039/C8SC00994E
Bayesian modelling and quantification of Raman spectroscopy
Moores Matthew, Gracie Kirsten, Carson Jake, Faulds Karen, Graham Duncan, Girolami Mark
Annals of Applied Statistics, (2018)
Development of a label-free Raman imaging technique for differentiation of malaria parasite infected from non-infected tissue
Frame Laura, Brewer James, Lee Rebecca, Faulds Karen, Graham Duncan
Analyst Vol 143, pp. 157-163, (2018)
http://dx.doi.org/10.1039/C7AN01760J

more publications

Research interests

Our research focuses on using surface enhanced Raman scattering (SERS) to create new approaches to bioanalysis for use in the life and clinical sciences.  SERS is a spectroscopic technique that offers significant advantages over other established techniques such as fluorescence and our research has focused on highlighting the advantages, creating new examples of increased capability in life science applications and interacting with end users to shape future step changes in research.  Our research centres around using the inherent sensitivity of SERS for the detection of target DNA or proteins using signal amplification methods to enhance the signal rather than using target amplification methods such as PCR.  Our work has focussed on exploiting the sensitivity of SERS for quantitative analysis of biomolecules as well as exploiting one of the key advantages of SERS, the ability to analyse multiple analytes in one sample.  This allows more information to be gained per analysis as well as giving information about complex systems that are intrinsically difficult to measure.

Professional activities

XXI SEQA's Meeting, Valencia
Speaker
9/2019
BBSRC (Biotech & Biological Sciences Research Council) (External organisation)
Advisor
3/2018
8th Chemical Nanoscience Symposium
Speaker
3/2018
Spring SciX
Participant
3/2018
Pittcon
Speaker
2/2018
Pittcon
Participant
2/2018

more professional activities

Projects

Optical Detection of Listeria in the Chilled Food Environment using Bionanosensors (Industrial Partnership Award) / R170553-1
Faulds, Karen (Principal Investigator) Graham, Duncan (Co-investigator)
Period 01-Mar-2018 - 28-Feb-2021
OPTIMA - Defining tumour margins using next generation photoacoustic imaging
Flockhart, Gordon (Principal Investigator) Uttamchandani, Deepak (Academic) Faulds, Karen (Academic) Graham, Duncan (Principal Investigator)
Photoacoustic imaging (PAI) overcomes one of the main limitations of optical microscopies, namely their difficulty with imaging tissue samples of thickness greater than a few hundred micrometres, due to the strong light scattering from biological tissue which reduces image contrast and resolution. PAI overcomes this problem by focusing pulsed laser light deep inside tissue samples, thereby generating wideband acoustic waves (via an optical-thermal-mechanical process) which are detected ultrasonically to generate an image.
Period 01-Sep-2016 - 01-Sep-2020
EPSRC Institutional Sponsorship: Global Challenges Research Fund (GCRF) / R160677-106
Graham, Duncan (Principal Investigator) Faulds, Karen (Co-investigator)
Period 01-Jun-2016 - 31-Mar-2017
Doctoral Training Partnership (DTP 2016-2017 University of Strathclyde) | Neilson, Eilidh Jeanette
Graham, Duncan (Principal Investigator) Faulds, Karen (Co-investigator) Neilson, Eilidh Jeanette (Research Co-investigator)
Period 01-Oct-2016 - 01-Oct-2020
Optical Detection of Listeria in the Chilled Food Environment using Bionanosensors (Industrial Partnership Award)
Faulds, Karen (Principal Investigator) Graham, Duncan (Co-investigator)
Period 01-Mar-2018 - 28-Feb-2021
Industrial Case Account 2016 | Thomson, Caitlin
Graham, Duncan (Principal Investigator) Faulds, Karen (Co-investigator) Thomson, Caitlin (Research Co-investigator)
Period 01-Oct-2016 - 01-Oct-2020

more projects

Address

Pure and Applied Chemistry
Technology Innovation Centre

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