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Professor Karen Faulds

Pure and Applied Chemistry

Publications

Surface enhanced resonance Raman spectroscopy (SERRS) for probing through plastic and tissue barriers using a handheld spectrometer
Nicolson Fay, Jamieson Lauren E., Mabbott Samuel, Plakas Konstantinos, Shand Neil C., Detty Michael R., Graham Duncan, Faulds Karen
Analyst, (2018)
Synergistic electrodeposition of bilayer films and analysis by Raman spectroscopy
Elmasly Saadeldin E.T., Guerrini Luca, Cameron Joseph, Kanibolotsky Alexander L., Findlay Neil J., Faulds Karen, Skabara Peter J.
Beilstein Journal of Organic Chemistry Vol 14, pp. 2186-2189, (2018)
http://dx.doi.org/10.3762/bjoc.14.191
Ratiometric Raman imaging reveals the new anti-cancer potential of lipid targeting drugs
Jamieson Lauren E., Wetherill Corinna, Faulds Karen, Graham Duncan
Chemical Science, (2018)
Multiplex imaging of live breast cancer tumour models through tissue using handheld surface enhanced spatially offset resonance Raman spectroscopy (SESORRS)
Nicolson Fay, Jamieson Lauren E., Mabbott Samuel, Plakas Konstantinos, Shand Neil C., Detty Michael R., Graham Duncan, Faulds Karen
Chemical Communications Vol 54, pp. 8530-8533 , (2018)
http://dx.doi.org/10.1039/C8CC04267E
Tracking intracellular uptake and localisation of alkyne tagged fatty acids using Raman spectroscopy
Jamieson Lauren E., Greaves Jennifer, McLellan Jayde A., Munro Kevin R., Tomkinson Nicholas C.O., Chamberlain Luke H., Faulds Karen, Graham Duncan
Spectrochimica Acta - Part A: Molecular and Biomolecular Spectroscopy Vol 197, pp. 30-36, (2018)
http://dx.doi.org/10.1016/j.saa.2018.01.064
Introducing 12 new dyes for use with oligonucleotide functionalised silver nanoparticles for DNA detection with SERS
Pala L., Mabbott S., Faulds K., Bedics M. A., Detty M. R., Graham D.
RSC Advances Vol 2018, pp. 17685-17693, (2018)
http://dx.doi.org/10.1039/C8RA01998C

more publications

Research interests

Our research focuses on using surface enhanced Raman scattering (SERS) to create new approaches to bioanalysis for use in the life and clinical sciences.  SERS is a spectroscopic technique that offers significant advantages over other established techniques such as fluorescence and our research has focused on highlighting the advantages, creating new examples of increased capability in life science applications and interacting with end users to shape future step changes in research.  Our research centres around using the inherent sensitivity of SERS for the detection of target DNA or proteins using signal amplification methods to enhance the signal rather than using target amplification methods such as PCR.  Our work has focussed on exploiting the sensitivity of SERS for quantitative analysis of biomolecules as well as exploiting one of the key advantages of SERS, the ability to analyse multiple analytes in one sample.  This allows more information to be gained per analysis as well as giving information about complex systems that are intrinsically difficult to measure.

Professional activities

International Conference on Raman Spectroscopy (ICORS)
Keynote/plenary speaker
8/2018
PhD Viva Dundee
Examiner
5/2018
BBSRC (Biotech & Biological Sciences Research Council) (External organisation)
Member
3/2018
Spring SciX
Organiser
3/2018
8th Chemical Nanoscience Symposium
Invited speaker
3/2018
Pittcon
Invited speaker
2/2018

more professional activities

Projects

Doctoral Training Partnership (DTP 2016-2017 University of Strathclyde) | Plunkett, Maria Kathleen
Graham, Duncan (Principal Investigator) Faulds, Karen (Co-investigator) Plunkett, Maria Kathleen (Research Co-investigator)
Period 01-Oct-2017 - 01-Apr-2021
Optical Detection of Listeria in the Chilled Food Environment using Bionanosensors (Industrial Partnership Award) / R170553-1
Faulds, Karen (Principal Investigator) Graham, Duncan (Co-investigator)
Period 01-Jun-2018 - 28-May-2021
Catching Nucleation in Action with Surface Enhanced Raman Spectroscopy
Johnston, Karen (Principal Investigator) Faulds, Karen (Co-investigator)
Period 01-Sep-2018 - 01-Aug-2019
OPTIMA - Defining tumour margins using next generation photoacoustic imaging
Flockhart, Gordon (Principal Investigator) Uttamchandani, Deepak (Academic) Faulds, Karen (Academic) Graham, Duncan (Principal Investigator)
Photoacoustic imaging (PAI) overcomes one of the main limitations of optical microscopies, namely their difficulty with imaging tissue samples of thickness greater than a few hundred micrometres, due to the strong light scattering from biological tissue which reduces image contrast and resolution. PAI overcomes this problem by focusing pulsed laser light deep inside tissue samples, thereby generating wideband acoustic waves (via an optical-thermal-mechanical process) which are detected ultrasonically to generate an image.
Period 01-Sep-2016 - 01-Sep-2020
EPSRC Institutional Sponsorship: Global Challenges Research Fund (GCRF) / R160677-106
Graham, Duncan (Principal Investigator) Faulds, Karen (Co-investigator)
Period 01-Jun-2016 - 31-Mar-2017
EPSRC i-sense IRC: Ultra-Sensitive Enhanced NanoSensing of Anti-Microbial Resistance (u-Sense)
Graham, Duncan (Principal Investigator) Faulds, Karen (Co-investigator)
Period 01-Oct-2018 - 31-Aug-2022

more projects

Address

Pure and Applied Chemistry
Technology Innovation Centre

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