Professor Karen Faulds

Pure and Applied Chemistry

Publications

Detection of estrogen receptor alpha and assessment of fulvestrant activity in MCF-7 tumour spheroids using microfluidics and SERS
Kapara Anastasia, Findlay Paterson Karla A, Brunton Valerie G, Graham Duncan, Zagnoni Michele, Faulds Karen
Analytical Chemistry (2021)
https://doi.org/10.1021/acs.analchem.1c00188
Effect of glycine on aggregation of citrate-functionalised gold nanoparticles and SERS measurements
Vesga Maria J, McKechnie David, Laing Stacey, Kearns Hayleigh, Faulds Karen, Johnston Karen, Sefcik Jan
Colloids and Surfaces A: Physicochemical and Engineering Aspects (2021)
Ratiometric sensing of fluoride ions using Raman spectroscopy
Tipping William J, Wilson Liam T, Blaseio Sonja K, Tomkinson Nick C O, Faulds Karen, Graham Duncan
Chemical Communications Vol 56, pp. 14463-14466 (2020)
https://doi.org/10.1039/D0CC05939K
Characterisation of estrogen receptor alpha (ERα) expression in breast cancer cells and effect of drug treatment using targeted nanoparticles and SERS
Kapara Anastasia, Brunton Valerie G, Graham Duncan, Faulds Karen
Analyst Vol 145, pp. 7225-7233 (2020)
https://doi.org/10.1039/D0AN01532F
Dynamic pH measurements of intracellular pathways using nano-plasmonic assemblies
Bando Kazuki, Zhang Zhiqiang, Graham Duncan, Faulds Karen, Fujita Katumasa, Kawata Satoshi
Analyst Vol 145, pp. 5768-5775 (2020)
https://doi.org/10.1039/d0an00986e
Modulation of interparticle gap for enhanced SERS sensitivity in chemically stable Ag@Au hetero-architectures
Wu Chunfang, Hu Qing, Benison Melissa, Faulds Karen, Graham Duncan
New Journal of Chemistry Vol 44, pp. 13843-13851 (2020)
https://doi.org/10.1039/d0nj02657c

More publications

Research interests

Our research focuses on using surface enhanced Raman scattering (SERS) to create new approaches to bioanalysis for use in the life and clinical sciences.  SERS is a spectroscopic technique that offers significant advantages over other established techniques such as fluorescence and our research has focused on highlighting the advantages, creating new examples of increased capability in life science applications and interacting with end users to shape future step changes in research.  Our research centres around using the inherent sensitivity of SERS for the detection of target DNA or proteins using signal amplification methods to enhance the signal rather than using target amplification methods such as PCR.  Our work has focussed on exploiting the sensitivity of SERS for quantitative analysis of biomolecules as well as exploiting one of the key advantages of SERS, the ability to analyse multiple analytes in one sample.  This allows more information to be gained per analysis as well as giving information about complex systems that are intrinsically difficult to measure.

Professional activities

Photonics Spectra Conference
Invited speaker
11/1/2021
Institute of Physics (IoP)- Optics in Clinical Practice Conference
Invited speaker
2/12/2020
RSC Molecular Spectroscopy Group
Invited speaker
26/8/2020
Analyst (Journal)
Associate Editor
8/2020
Pittcon
Invited speaker
3/2020
Royal Society of Chemistry Analytical Division Council (External organisation)
Member
2020

More professional activities

Projects

Plasmonic Photothermal Heating of Gold Nanoparticles Increases Raman Scattering
Graham, Duncan (Principal Investigator) Faulds, Karen (Co-investigator) Tuttle, Tell (Co-investigator)
01-Jan-2021 - 31-Jan-2024
GlasBioPhys: An integrated facility for the analysis of biomolecular interactions (19ALERT Mid-range equipment initiative)
Burley, Glenn (Principal Investigator) Chamberlain, Luke (Co-investigator) Faulds, Karen (Co-investigator) Hoskisson, Paul (Co-investigator)
11-Jan-2020 - 09-Jan-2021
Development of Point of Use Bionanosensors
Faulds, Karen (Principal Investigator) Graham, Duncan (Co-investigator)
01-Jan-2020 - 31-Jan-2024
Doctoral Training Partnership 2020-2021 University of Strathclyde | Clark, Benjamin
Faulds, Karen (Principal Investigator) Graham, Duncan (Co-investigator) Clark, Benjamin (Research Co-investigator)
01-Jan-2020 - 01-Jan-2024
Catching nucleation in action using surface enhanced Raman spectroscopy
Johnston, Karen (Principal Investigator) Faulds, Karen (Co-investigator) Sefcik, Jan (Co-investigator)
01-Jan-2020 - 30-Jan-2023
Doctoral Training Partnership 2018-19 University of Strathclyde | Buchanan, Craig
Graham, Duncan (Principal Investigator) Faulds, Karen (Co-investigator) Buchanan, Craig (Research Co-investigator)
01-Jan-2019 - 01-Jan-2023

More projects

Address

Pure and Applied Chemistry
Technology Innovation Centre

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