Professor Karen Faulds

Pure and Applied Chemistry

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Publications

Expanding the range of bioorthogonal tags for multiplex stimulated Raman scattering microscopy
Murphy Neville, Tipping William J, Braddick Henry J, Wilson Liam T, Tomkinson Nicholas CO, Faulds Karen, Graham Duncan, Farràs Pau
Angewandte Chemie International Edition Vol 62 (2023)
https://doi.org/10.1002/anie.202311530
Optoplasmonic effects in highly curved surfaces for catalysis, photothermal heating, and SERS
Masson Jean-Francois, Wallace Gregory Q, Asselin Jérémie, Ten Andrey, Hojjat Jodaylami Maryam, Faulds Karen, Graham Duncan, Biggins John S, Ringe Emilie
ACS Applied Materials and Interfaces Vol 15, pp. 46181–46194 (2023)
https://doi.org/10.1021/acsami.3c07880
Light-up split aptamers : binding thermodynamics and kinetics for sensing
Zhao Yichen, Patel Nikesh, Sun Peihuan, Faulds Karen, Graham Duncan, Liu Juewen
Analyst Vol 148, pp. 5612-5618 (2023)
https://doi.org/10.1039/D3AN01368E
Evaluating nanoparticle localisation in glioblastoma multicellular tumour spheroids by surface enhanced Raman scattering
McCabe Samantha M, Wallace Gregory Q, Sloan-Dennison Sian, Tipping William J, Shand Neil C, Graham Duncan, Boyd Marie, Faulds Karen
Analyst Vol 148, pp. 3247-3256 (2023)
https://doi.org/10.1039/D3AN00751K
Understanding radiation response and cell cycle variation in brain tumour cells using Raman spectroscopy
Hill Iona E, Boyd Marie, Milligan Kirsty, Jenkins Cerys A, Sorensen Annette, Jirasek Andrew, Graham Duncan, Faulds Karen
Analyst Vol 148, pp. 2594-2608 (2023)
https://doi.org/10.1039/D3AN00121K
Synthesis, characterisation and multi-modal intracellular mapping of cisplatin nano-conjugates
Leventi Aristea Anna, Braddick Henry J, Billimoria Kharmen, Wallace Gregory Q, Goenaga-Infante Heidi, Tomkinson Nicholas CO, Faulds Karen, Graham Duncan
Chemical Communications Vol 59, pp. 6395-6398 (2023)
https://doi.org/10.1039/d3cc00925d

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Research Interests

Our research focuses on using surface enhanced Raman scattering (SERS) to create new approaches to bioanalysis for use in the life and clinical sciences.  SERS is a spectroscopic technique that offers significant advantages over other established techniques such as fluorescence and our research has focused on highlighting the advantages, creating new examples of increased capability in life science applications and interacting with end users to shape future step changes in research.  Our research centres around using the inherent sensitivity of SERS for the detection of target DNA or proteins using signal amplification methods to enhance the signal rather than using target amplification methods such as PCR.  Our work has focussed on exploiting the sensitivity of SERS for quantitative analysis of biomolecules as well as exploiting one of the key advantages of SERS, the ability to analyse multiple analytes in one sample.  This allows more information to be gained per analysis as well as giving information about complex systems that are intrinsically difficult to measure.

Professional Activities

Development of a Spatially Resolved Spectroscopy probe for In-line Monitoring of Pharmaceutical Drying
Contributor
21/3/2023
Seminar
Invited speaker
11/2022
SciX 2022
Invited speaker
10/2022
SciX 2022
Keynote/plenary speaker
10/2022
RSC Advances (Journal)
Editor
9/2022
Seminar
Invited speaker
9/2022

More professional activities

Projects

DTP 2224 University of Strathclyde | Merchant, Andrew
Faulds, Karen (Principal Investigator) Graham, Duncan (Co-investigator) Merchant, Andrew (Research Co-investigator)
01-Jan-2023 - 01-Jan-2027
New Capability for Bacterial Testing in the Food Production Environment
Faulds, Karen (Principal Investigator) Graham, Duncan (Co-investigator) May, Hayleigh (Research Co-investigator)
01-Jan-2022 - 31-Jan-2024
DTP 2224 University of Strathclyde | Gale, Cameron
Faulds, Karen (Principal Investigator) Graham, Duncan (Co-investigator) Gale, Cameron (Research Co-investigator)
01-Jan-2022 - 01-Jan-2026
Strathclyde CDT: Healthcare Nanotechnologies
Perrie, Yvonne (Principal Investigator) Rattray, Zahra (Principal Investigator) Hoskins, Clare (Principal Investigator) Faulds, Karen (Principal Investigator) Graham, Duncan (Principal Investigator)
01-Jan-2022 - 30-Jan-2025
Multiscale Metrology Suite for Next-generation Healthcare Technologies (EPSRC Strategic Equipment)
Rattray, Zahra (Principal Investigator) Bruns, Nico (Co-investigator) Faulds, Karen (Co-investigator) Graham, Duncan (Co-investigator) Halbert, Gavin (Co-investigator) Hoskins, Clare (Co-investigator) McArthur, Stephen (Co-investigator) Perrie, Yvonne (Co-investigator) Reid, Stuart (Co-investigator) Seib, Philipp (Co-investigator)
01-Jan-2021 - 31-Jan-2024
MICA: Point-of-care assessment of drug-induced liver injury (POC-DILI)
Graham, Duncan (Principal Investigator) Faulds, Karen (Co-investigator) Sloan-Dennison, Sian (Research Co-investigator)
01-Jan-2021 - 30-Jan-2024

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Contact

Professor Karen Faulds
Pure and Applied Chemistry

Email: karen.faulds@strath.ac.uk
Tel: 548 2507