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Prof Karen Faulds

Pure and Applied Chemistry

Publications

Development of a label-free Raman imaging technique for differentiation of malaria parasite infected from non-infected tissue
Frame Laura, Brewer James, Lee Rebecca, Faulds Karen, Graham Duncan
Analyst, (2017)
High figure of merit (FOM) of Bragg modes in Au-coated nanodisk arrays for plasmonic sensing
Couture Maxime, Brule Thibault, Laing Stacey, Cui Wenli, Sarkar Mitradeep, Charron Benjamin, Faulds Karen, Peng Wei, Canva Michael, Masson Jean-Francois
Small Vol 13, (2017)
http://dx.doi.org/10.1002/smll.201700908
Organoimido-polyoxometalate nonlinear optical chromophores : a structural, spectroscopic, and computational study
Al-Yasari Ahmed, Van Steerteghem Nick, Kearns Hayleigh, El Moll Hani, Faulds Karen, Wright Joseph A., Brunschwig Bruce S., Clays Koen, Fielden John
Inorganic Chemistry Vol 56, pp. 10181-10194, (2017)
http://dx.doi.org/10.1021/acs.inorgchem.7b00708
Surface-enhanced Raman spectroscopy for in vivo biosensing
Laing Stacey, Jamieson Lauren E., Faulds Karen, Graham Duncan
Nature Reviews Chemistry Vol 1, (2017)
http://dx.doi.org/10.1038/s41570-017-0060
Bioanalytical measurements enabled by surface-enhanced Raman scattering (SERS) probes
Jamieson Lauren E., Asiala Steven M., Gracie Kirsten, Faulds Karen, Graham Duncan
Annual Review of Analytical Chemistry Vol 10, (2017)
http://dx.doi.org/10.1146/annurev-anchem-071015-041557
Sensitive SERS nanotags for use with a hand-held 1064 nm Raman spectrometer
Kearns Hayleigh, Ali Fatima, Bedics Matthew A., Shand Neil C., Faulds Karen, Detty Michael R., Graham Duncan
Royal Society Open Science Vol 4, (2017)
http://dx.doi.org/10.1098/rsos.170422

more publications

Research interests

Our research focuses on using surface enhanced Raman scattering (SERS) to create new approaches to bioanalysis for use in the life and clinical sciences.  SERS is a spectroscopic technique that offers significant advantages over other established techniques such as fluorescence and our research has focused on highlighting the advantages, creating new examples of increased capability in life science applications and interacting with end users to shape future step changes in research.  Our research centres around using the inherent sensitivity of SERS for the detection of target DNA or proteins using signal amplification methods to enhance the signal rather than using target amplification methods such as PCR.  Our work has focussed on exploiting the sensitivity of SERS for quantitative analysis of biomolecules as well as exploiting one of the key advantages of SERS, the ability to analyse multiple analytes in one sample.  This allows more information to be gained per analysis as well as giving information about complex systems that are intrinsically difficult to measure.

Professional activities

International Conference on Advanced Vibrational Spectroscopy (ICAVS)
Keynote/plenary speaker
6/2017
PhD Examiner, University of Manchester
External Examiner
11/5/2017
Seminar, University of Osaka, Japan
Invited speaker
5/2017
Biomedical Raman International Symposium, Tokyo, Japan
Invited speaker
5/2017
Invited Talk, Clircon Conference
Invited speaker
4/2017
Healthcare Symposium, University of Bath
Invited speaker
4/2017

more professional activities

Projects

OPTIMA - Defining tumour margins using next generation photoacoustic imaging
Flockhart, Gordon (Principal Investigator) Uttamchandani, Deepak (Academic) Faulds, Karen (Academic) Graham, Duncan (Principal Investigator)
Photoacoustic imaging (PAI) overcomes one of the main limitations of optical microscopies, namely their difficulty with imaging tissue samples of thickness greater than a few hundred micrometres, due to the strong light scattering from biological tissue which reduces image contrast and resolution. PAI overcomes this problem by focusing pulsed laser light deep inside tissue samples, thereby generating wideband acoustic waves (via an optical-thermal-mechanical process) which are detected ultrasonically to generate an image.
Period 01-Sep-2016 - 01-Sep-2020
EPSRC Institutional Sponsorship: Global Challenges Research Fund (GCRF) / R160677-106
Graham, Duncan (Principal Investigator) Faulds, Karen (Co-investigator)
Period 01-Jun-2016 - 31-Mar-2017
Doctoral Training Partnership (DTP 2016-2017 University of Strathclyde) | Neilson, Eilidh Jeanette
Graham, Duncan (Principal Investigator) Faulds, Karen (Co-investigator) Neilson, Eilidh Jeanette (Research Co-investigator)
Period 01-Oct-2016 - 01-Oct-2020
Industrial Case Account 2016 | Thomson, Caitlin
Graham, Duncan (Principal Investigator) Faulds, Karen (Co-investigator) Thomson, Caitlin (Research Co-investigator)
Period 01-Oct-2016 - 01-Oct-2020
Doctoral Training Partnership (DTP 2016-2017 University of Strathclyde) | Ali, Fatima
Graham, Duncan (Principal Investigator) Faulds, Karen (Co-investigator) Ali, Fatima (Research Co-investigator)
Period 01-Oct-2016 - 01-Apr-2020
DSTL- Detection of multiple explosives (RN) | Norman, Rachel
Faulds, Karen (Principal Investigator) Graham, Duncan (Co-investigator) Norman, Rachel (Research Co-investigator)
Period 01-Oct-2012 - 24-Jun-2016

more projects

Address

Pure and Applied Chemistry
Technology Innovation Centre

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