Professor Karen Faulds

Pure and Applied Chemistry

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Publications

New insights into lipid and fatty acid metabolism from Raman spectroscopy
Greig Justin C, Tipping William J, Graham Duncan, Faulds Karen, Gould Gwyn W
Analyst (2024)
https://doi.org/10.1039/D4AN00846D
Advancing SERS as a quantitative technique : challenges, considerations, and correlative approaches to aid validation
Sloan-Dennison Sian, Wallace Gregory Q, Hassanain Waleed A, Laing Stacey, Faulds Karen, Graham Duncan
Nano Convergence Vol 11 (2024)
https://doi.org/10.1186/s40580-024-00443-4
Ultra-sensitive dual ELONA/SERS-RPA multiplex diagnosis of antimicrobial resistance
Hassanain Waleed A, Johnson Christopher L, Faulds Karen, Keegan Neil, Graham Duncan
Analytical Chemistry Vol 96, pp. 12093-12101 (2024)
https://doi.org/10.1021/acs.analchem.4c02165
Thiol-polyethylene glycol-folic acid (HS-PEG-FA) induced aggregation of Au@Ag nanoparticles : a SERS and extinction UV–Vis spectroscopy combined study
Verdin Alexandre, Malherbe Cedric, Sloan-Dennison Sian, Faulds Karen, Graham Duncan, Eppe Gauthier
Spectrochimica Acta - Part A: Molecular and Biomolecular Spectroscopy Vol 322 (2024)
https://doi.org/10.1016/j.saa.2024.124848
Label-free screening of drug-induced liver injury using stimulated Raman scattering microscopy and spectral phasor analysis
Tipping William J, Wilson Liam T, Tomkinson Nicholas C O, Faulds Karen, Graham Duncan
Analytical Chemistry Vol 96, pp. 10639-10647 (2024)
https://doi.org/10.1021/acs.analchem.4c01285
Live chicken egg embryos as an alternative in vivo tumour model for deep surface enhanced Raman spectroscopy
McCabe Samantha M, Gardiner Hannah, Mullen Calum, Wallace Gregory Q, Shand Neil C, Mullen Alexander B, Horan Linda, Graham Duncan, Faulds Karen, Boyd Marie
Analyst Vol 149, pp. 3513-3517 (2024)
https://doi.org/10.1039/d4an00617h

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Research Interests

Our research focuses on using surface enhanced Raman scattering (SERS) to create new approaches to bioanalysis for use in the life and clinical sciences.  SERS is a spectroscopic technique that offers significant advantages over other established techniques such as fluorescence and our research has focused on highlighting the advantages, creating new examples of increased capability in life science applications and interacting with end users to shape future step changes in research.  Our research centres around using the inherent sensitivity of SERS for the detection of target DNA or proteins using signal amplification methods to enhance the signal rather than using target amplification methods such as PCR.  Our work has focussed on exploiting the sensitivity of SERS for quantitative analysis of biomolecules as well as exploiting one of the key advantages of SERS, the ability to analyse multiple analytes in one sample.  This allows more information to be gained per analysis as well as giving information about complex systems that are intrinsically difficult to measure.

Professional Activities

Development of a Spatially Offset Raman Spectroscopy Probe for Monitoring Pharmaceutical Drying
Contributor
25/1/2024
Development of a Spatially Resolved Spectroscopy probe for In-line Monitoring of Pharmaceutical Drying
Contributor
21/3/2023
Seminar
Invited speaker
11/2022
SciX 2022
Keynote/plenary speaker
10/2022
SciX 2022
Invited speaker
10/2022
International conference on Raman Spectroscopy (ICORS)
Keynote/plenary speaker
9/2022

More professional activities

Projects

GLAS-CYTO: AN INTEGRATED FACILITY FOR THE BIOPHYSICAL ANALYSIS OF CELLULAR INTERACTIONS
Burley, Glenn (Principal Investigator) Chamberlain, Luke (Co-investigator) Chow, Shiao (Co-investigator) Corrigan, Damion (Co-investigator) Cunningham, Margaret Rose (Co-investigator) Faulds, Karen (Co-investigator) Jamieson, Craig (Co-investigator) Rattray, Zahra (Co-investigator) Tomkinson, Nick (Co-investigator) Taladriz Sender, Andrea (Research Co-investigator)
01-Aug-2024 - 31-Jul-2025
Spectral Phasor-based Automated Raman Histopathology and Tissue Analysis (SPARTAN)
Faulds, Karen (Principal Investigator)
01-Jun-2024 - 30-Nov-2024
Rapid Bacterial Testing
Faulds, Karen (Principal Investigator) Graham, Duncan (Co-investigator)
05-Feb-2024 - 30-Nov-2024
DTP 2224 University of Strathclyde | Merchant, Andrew
Faulds, Karen (Principal Investigator) Graham, Duncan (Co-investigator) Merchant, Andrew (Research Co-investigator)
01-Oct-2023 - 01-Apr-2027
New Capability for Bacterial Testing in the Food Production Environment
Faulds, Karen (Principal Investigator) Graham, Duncan (Co-investigator) May, Hayleigh (Research Co-investigator)
01-Nov-2022 - 31-Oct-2024
Self-assembling silk for cell and drug delivery
Rattray, Zahra (Principal Investigator) Faulds, Karen (Principal Investigator) ROAMCHARERN, Napaporn (Post Grad Student)
01-Oct-2022 - 30-Sep-2025

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Contact

Professor Karen Faulds
Pure and Applied Chemistry

Email: karen.faulds@strath.ac.uk
Tel: 548 2507