Professor Karen Faulds

Pure and Applied Chemistry

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Publications

Ultra-sensitive dual ELONA/SERS-RPA multiplex diagnosis of antimicrobial resistance
Hassanain Waleed A, Johnson Christopher L, Faulds Karen, Keegan Neil, Graham Duncan
Analytical Chemistry Vol 96, pp. 12093-12101 (2024)
https://doi.org/10.1021/acs.analchem.4c02165
Label-free screening of drug-induced liver injury using stimulated Raman scattering microscopy and spectral phasor analysis
Tipping William J, Wilson Liam T, Tomkinson Nicholas C O, Faulds Karen, Graham Duncan
Analytical Chemistry Vol 96, pp. 10639-10647 (2024)
https://doi.org/10.1021/acs.analchem.4c01285
Live chicken egg embryos as an alternative in vivo tumour model for deep surface enhanced Raman spectroscopy
McCabe Samantha M, Gardiner Hannah, Mullen Calum, Wallace Gregory Q, Shand Neil C, Mullen Alexander B, Horan Linda, Graham Duncan, Faulds Karen, Boyd Marie
Analyst Vol 149, pp. 3513-3517 (2024)
https://doi.org/10.1039/d4an00617h
Cytokeratin-18 is a sensitive biomarker of alanine transaminase increase in a placebo-controlled, randomized, crossover trial of therapeutic paracetamol dosing (PATH-BP biomarker substudy)
Scullion Kathleen M, MacIntyre Iain M, Sloan-Dennison Sian, Clark Benjamin, Fineran Paul, Mair Joanne, Creasey David, Rathmell Cicely, Faulds Karen, Graham Duncan, Webb David J, Dear James W
Toxicological Sciences Vol 199, pp. 203-209 (2024)
https://doi.org/10.1093/toxsci/kfae031
Scalable slot-die coated flexible supercapacitors from upcycled PET face shields
Reddygunta Kiran Kumar Reddy, Callander Andrew, Šiller Lidija, Faulds Karen, Berlouis Leonard, Ivaturi Aruna
RSC Advances Vol 14, pp. 12781-12795 (2024)
https://doi.org/10.1039/D2RA06809E
Multiplex detection of the big five carbapenemase genes using solid-phase recombinase polymerase amplification
Johnson Christopher L, Setterfield Matthew A, Hassanain Waleed A, Wipat Anil, Pocock Matthew, Faulds Karen, Graham Duncan, Keegan Neil
Analyst Vol 149, pp. 1527-1536 (2024)
https://doi.org/10.1039/d3an01747h

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Research Interests

Our research focuses on using surface enhanced Raman scattering (SERS) to create new approaches to bioanalysis for use in the life and clinical sciences.  SERS is a spectroscopic technique that offers significant advantages over other established techniques such as fluorescence and our research has focused on highlighting the advantages, creating new examples of increased capability in life science applications and interacting with end users to shape future step changes in research.  Our research centres around using the inherent sensitivity of SERS for the detection of target DNA or proteins using signal amplification methods to enhance the signal rather than using target amplification methods such as PCR.  Our work has focussed on exploiting the sensitivity of SERS for quantitative analysis of biomolecules as well as exploiting one of the key advantages of SERS, the ability to analyse multiple analytes in one sample.  This allows more information to be gained per analysis as well as giving information about complex systems that are intrinsically difficult to measure.

Professional Activities

Development of a Spatially Offset Raman Spectroscopy Probe for Monitoring Pharmaceutical Drying
Contributor
25/1/2024
Development of a Spatially Resolved Spectroscopy probe for In-line Monitoring of Pharmaceutical Drying
Contributor
21/3/2023
Seminar
Invited speaker
11/2022
SciX 2022
Keynote/plenary speaker
10/2022
SciX 2022
Invited speaker
10/2022
Seminar
Invited speaker
9/2022

More professional activities

Projects

Spectral Phasor-based Automated Raman Histopathology and Tissue Analysis (SPARTAN)
Faulds, Karen (Principal Investigator)
01-Jan-2024 - 30-Jan-2024
Rapid Bacterial Testing
Faulds, Karen (Principal Investigator) Graham, Duncan (Co-investigator)
05-Jan-2024 - 30-Jan-2024
DTP 2224 University of Strathclyde | Merchant, Andrew
Faulds, Karen (Principal Investigator) Graham, Duncan (Co-investigator) Merchant, Andrew (Research Co-investigator)
01-Jan-2023 - 01-Jan-2027
New Capability for Bacterial Testing in the Food Production Environment
Faulds, Karen (Principal Investigator) Graham, Duncan (Co-investigator) May, Hayleigh (Research Co-investigator)
01-Jan-2022 - 31-Jan-2024
DTP 2224 University of Strathclyde | Gale, Cameron
Faulds, Karen (Principal Investigator) Graham, Duncan (Co-investigator) Gale, Cameron (Research Co-investigator)
01-Jan-2022 - 01-Jan-2026
Self-assembling silk for cell and drug delivery
Rattray, Zahra (Principal Investigator) Faulds, Karen (Principal Investigator) ROAMCHARERN, Napaporn (Post Grad Student)
01-Jan-2022 - 30-Jan-2025

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Contact

Professor Karen Faulds
Pure and Applied Chemistry

Email: karen.faulds@strath.ac.uk
Tel: 548 2507