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Professor Karen Faulds

Pure and Applied Chemistry

Publications

Bayesian modelling and quantification of Raman spectroscopy
Moores Matthew, Gracie Kirsten, Carson Jake, Faulds Karen, Graham Duncan, Girolami Mark
Annals of Applied Statistics, (2018)
Tracking intracellular uptake and localisation of alkyne tagged fatty acids using Raman spectroscopy
Jamieson Lauren E., Greaves Jennifer, McLellan Jayde A., Munro Kevin R., Tomkinson Nicholas C.O., Chamberlain Luke H., Faulds Karen, Graham Duncan
Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy, (2018)
Development of a label-free Raman imaging technique for differentiation of malaria parasite infected from non-infected tissue
Frame Laura, Brewer James, Lee Rebecca, Faulds Karen, Graham Duncan
Analyst Vol 143, pp. 157-163, (2018)
http://dx.doi.org/10.1039/C7AN01760J
Resonance Raman detection of antioxidants using an iron oxide nanoparticle catalysed decolourisation assay
Sloan-Dennison Sian, Shand Neil C., Graham Duncan, Faulds Karen
Analyst Vol 142, pp. 4715-4720, (2017)
http://dx.doi.org/10.1039/c7an01151b
Through barrier detection of ethanol using handheld Raman spectroscopy — Conventional Raman versus spatially offset Raman spectroscopy (SORS)
Nicolson Fay, Jamieson Lauren E., Mabbott Samuel, Shand Neil C., Graham Duncan, Faulds Karen
Journal of Raman Spectroscopy Vol 48, pp. 1828-1838, (2017)
http://dx.doi.org/10.1002/jrs.5258
SERS detection of multiple antimicrobial-resistant pathogens using nanosensors
Kearns Hayleigh, Goodacre Royston, Jamieson Lauren E., Graham Duncan, Faulds Karen
Analytical Chemistry Vol 89, pp. 12666-12673, (2017)
http://dx.doi.org/10.1021/acs.analchem.7b02653

more publications

Research interests

Our research focuses on using surface enhanced Raman scattering (SERS) to create new approaches to bioanalysis for use in the life and clinical sciences.  SERS is a spectroscopic technique that offers significant advantages over other established techniques such as fluorescence and our research has focused on highlighting the advantages, creating new examples of increased capability in life science applications and interacting with end users to shape future step changes in research.  Our research centres around using the inherent sensitivity of SERS for the detection of target DNA or proteins using signal amplification methods to enhance the signal rather than using target amplification methods such as PCR.  Our work has focussed on exploiting the sensitivity of SERS for quantitative analysis of biomolecules as well as exploiting one of the key advantages of SERS, the ability to analyse multiple analytes in one sample.  This allows more information to be gained per analysis as well as giving information about complex systems that are intrinsically difficult to measure.

Professional activities

International Conference on Advanced Vibrational Spectroscopy (ICAVS)
Keynote/plenary speaker
6/2017
PhD Examiner, University of Manchester
External Examiner
11/5/2017
Seminar, University of Osaka, Japan
Invited speaker
5/2017
Biomedical Raman International Symposium, Tokyo, Japan
Invited speaker
5/2017
Invited Talk, Clircon Conference
Invited speaker
4/2017
Healthcare Symposium, University of Bath
Invited speaker
4/2017

more professional activities

Projects

OPTIMA - Defining tumour margins using next generation photoacoustic imaging
Flockhart, Gordon (Principal Investigator) Uttamchandani, Deepak (Academic) Faulds, Karen (Academic) Graham, Duncan (Principal Investigator)
Photoacoustic imaging (PAI) overcomes one of the main limitations of optical microscopies, namely their difficulty with imaging tissue samples of thickness greater than a few hundred micrometres, due to the strong light scattering from biological tissue which reduces image contrast and resolution. PAI overcomes this problem by focusing pulsed laser light deep inside tissue samples, thereby generating wideband acoustic waves (via an optical-thermal-mechanical process) which are detected ultrasonically to generate an image.
Period 01-Sep-2016 - 01-Sep-2020
EPSRC Institutional Sponsorship: Global Challenges Research Fund (GCRF) / R160677-106
Graham, Duncan (Principal Investigator) Faulds, Karen (Co-investigator)
Period 01-Jun-2016 - 31-Mar-2017
Doctoral Training Partnership (DTP 2016-2017 University of Strathclyde) | Neilson, Eilidh Jeanette
Graham, Duncan (Principal Investigator) Faulds, Karen (Co-investigator) Neilson, Eilidh Jeanette (Research Co-investigator)
Period 01-Oct-2016 - 01-Oct-2020
Industrial Case Account 2016 | Thomson, Caitlin
Graham, Duncan (Principal Investigator) Faulds, Karen (Co-investigator) Thomson, Caitlin (Research Co-investigator)
Period 01-Oct-2016 - 01-Oct-2020
Doctoral Training Partnership (DTP 2016-2017 University of Strathclyde) | Ali, Fatima
Graham, Duncan (Principal Investigator) Faulds, Karen (Co-investigator) Ali, Fatima (Research Co-investigator)
Period 01-Oct-2016 - 01-Apr-2020
DSTL- Detection of multiple explosives (RN) | Norman, Rachel
Faulds, Karen (Principal Investigator) Graham, Duncan (Co-investigator)
Period 01-Oct-2012 - 24-Jun-2016

more projects

Address

Pure and Applied Chemistry
Technology Innovation Centre

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