Research interests
Our research focuses on using surface enhanced Raman scattering (SERS) to create new approaches to bioanalysis for use in the life and clinical sciences. SERS is a spectroscopic technique that offers significant advantages over other established techniques such as fluorescence and our research has focused on highlighting the advantages, creating new examples of increased capability in life science applications and interacting with end users to shape future step changes in research. Our research centres around using the inherent sensitivity of SERS for the detection of target DNA or proteins using signal amplification methods to enhance the signal rather than using target amplification methods such as PCR. Our work has focussed on exploiting the sensitivity of SERS for quantitative analysis of biomolecules as well as exploiting one of the key advantages of SERS, the ability to analyse multiple analytes in one sample. This allows more information to be gained per analysis as well as giving information about complex systems that are intrinsically difficult to measure.
Professional activities
- PhD Examiner, University of Manchester
- External Examiner
- 11/5/2017
- Seminar, University of Osaka, Japan
- Speaker
- 5/2017
- Biomedical Raman International Symposium, Tokyo, Japan
- Speaker
- 5/2017
- Invited Talk, Clircon Conference
- Speaker
- 4/2017
- Healthcare Symposium, University of Bath
- Speaker
- 4/2017
- Seminar, University of Bristol
- Speaker
- 2/2017
more professional activities
Projects
- OPTIMA - Defining tumour margins using next generation photoacoustic imaging
- Flockhart, Gordon (Principal Investigator) Uttamchandani, Deepak (Academic) Faulds, Karen (Academic) Graham, Duncan (Principal Investigator)
- Photoacoustic imaging (PAI) overcomes one of the main limitations of optical microscopies, namely their difficulty with imaging tissue samples of thickness greater than a few hundred micrometres, due to the strong light scattering from biological tissue which reduces image contrast and resolution. PAI overcomes this problem by focusing pulsed laser light deep inside tissue samples, thereby generating wideband acoustic waves (via an optical-thermal-mechanical process) which are detected ultrasonically to generate an image.
- Period 01-Sep-2016 - 01-Sep-2020
- EPSRC Institutional Sponsorship: Global Challenges Research Fund (GCRF) / R160677-106
- Graham, Duncan (Principal Investigator) Faulds, Karen (Co-investigator)
- Period 01-Jun-2016 - 31-Mar-2017
- Doctoral Training Partnership (DTP 2016-2017 University of Strathclyde) | Neilson, Eilidh Jeanette
- Graham, Duncan (Principal Investigator) Faulds, Karen (Co-investigator) Neilson, Eilidh Jeanette (Research Co-investigator)
- Period 01-Oct-2016 - 01-Oct-2020
- Industrial Case Account 2016 | Thomson, Caitlin
- Graham, Duncan (Principal Investigator) Faulds, Karen (Co-investigator) Thomson, Caitlin (Research Co-investigator)
- Period 01-Oct-2016 - 01-Oct-2020
- Doctoral Training Partnership (DTP 2016-2017 University of Strathclyde) | Ali, Fatima
- Graham, Duncan (Principal Investigator) Faulds, Karen (Co-investigator) Ali, Fatima (Research Co-investigator)
- Period 01-Oct-2016 - 01-Apr-2020
- DSTL- Detection of multiple explosives (RN) | Norman, Rachel
- Faulds, Karen (Principal Investigator) Graham, Duncan (Co-investigator) Norman, Rachel (Research Co-investigator)
- Period 01-Oct-2012 - 24-Jun-2016
more projects
Address
Pure and Applied Chemistry
Technology Innovation Centre
Technology Innovation Centre
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