Professor Paul Hoskisson

Strathclyde Institute of Pharmacy and Biomedical Sciences

Contact

Personal statement

Laboratory webpage is here http://paulhoskisson.weebly.com

Research in my group is focussed on the synthesis of antibiotics and the evolution of bacterial pathogens, using a range of techniques from molecular biology and biochemistry through to mathematical modelling and image analysis. The bacterial genus Streptomyces is the main focus of work in my Research Group due to its industrial importance, being responsible for producing around two thirds of all commercially important antibiotics as well as numerous anti-fungal, anti-helminthic and anti-cancer drugs. 

We also have an interest in evolution of metabolism, evolution of bacterial pathogens, genomics of actinobacteria and the exploitation of amphibian proteins for biotechnology. 

We use a range of techniques to study the biology of actinobacteria including molecular genetics, protein biochemistry, genomics, microscopy, physiology, advanced spectroscopy, mathematical modeling and bioinformatics.

I was elected as a member of the Royal Society of Edinburgh Young Academy of Scotland in 2014 and a Fellow of the Royal Society of Biology (FRSB) in 2016.

I am a member of the Microbiology Society, the American Society of Microbiology, the Biochemical Society, The Royal Society of Biology and British Herpetological Society.

I am a managing editor for Antonie van Leeuwenhoek International Journal of Microbiology, and sit on the editorial board for Microbial Genomics, Frontiers in Antimicrobials, resistance and chemotherapy, Frontiers in Microbial Physiology and Metabolism, Frontiers in Synthetic Biology and Metabolism and Nature Scientific Data and Nature Scientific Reports.I am a former Editor in Chief of Microbiology Today.

I am a Fellow of the Higher Education Academy.

I am interested in the use of Social media for communication of science and you can follow on Twitter @paulhoskisson

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Publications

Transcriptome landscapes of salt-susceptible rice cultivar IR29 associated with a plant growth promoting endophytic streptomyces
Kruasuwan Worarat, Lohmaneeratana Karan, Munnoch John T, Vongsangnak Wanwipa, Jantrasuriyarat Chatchawan, Hoskisson Paul A, Thamchaipenet Arinthip
Rice Vol 16, pp. 6 (2023)
https://doi.org/10.1186/s12284-023-00622-7
Multidrug-resistant E. coli encoding high genetic diversity in carbohydrate metabolism genes displace commensal E. coli from the intestinal tract
Connor Christopher H, Zucoloto Amanda Z, Munnoch John T, Yu Ian-Ling, Corander Jukka, Hoskisson Paul A, McDonald Braedon, McNally Alan
PLOS Biology Vol 21 (2023)
https://doi.org/10.1371/journal.pbio.3002329
16S rRNA phylogeny and clustering is not a reliable proxy for genome-based taxonomy in Streptomyces
Kiepas Angelika B, Hoskisson Paul A, Pritchard Leighton
(2023)
https://doi.org/10.1101/2023.08.15.553377
Prokaryotic ammonium transporters : what has three decades of research revealed?
Bizior Adriana, Williamson Gordon, Harris Thomas, Hoskisson Paul A, Javelle Arnaud
Microbiology Vol 169 (2023)
https://doi.org/10.1099/mic.0.001360
Rapid assessment of antibiotic susceptibility using a fully 3D-printed impedance- based biosensor
Domingo-Roca R, Lasserre P, Riordan L, Macdonald AR, Dobrea A, Duncan KR, Hannah S, Murphy M, Hoskisson PA, Corrigan DK
Biosensors and Bioelectronics X Vol 13 (2023)
https://doi.org/10.1016/j.biosx.2023.100308
On the evolution of natural product biosynthesis
Barona-Gómez Francisco, Chevrette Marc G, Hoskisson Paul A
Advances in Microbial Physiology (2023) (2023)
https://doi.org/10.1016/bs.ampbs.2023.05.001

More publications

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Professional Activities

Investigating the fractal nature of channels within E. coli biofilms with altered cell phenotype
Contributor
25/7/2023
Investigating the influence of cell shape on intra-colony channel architecture by fractal analysis of confocal microscopy biofilm images
Contributor
4/7/2023
Clearing up the dirt: Creating a tuneable and transparent 3D culture platform for soil microbes
Speaker
20/4/2023
Family disagreements: what do conflicts between whole-genome, core gene, MLST and 16S classifications tell us about Streptomyces?
Contributor
18/4/2023
Intra-colony channel morphology in Escherichia coli biofilms is governed by nutrient availability and substrate stiffness
Contributor
1/12/2022
External Examiner at University of Leeds, BSc in Microbiology
Examiner
1/10/2022

More professional activities

Projects

Taming of the Streptomycete: Understanding the rules of domestication in antibiotic-producing bacteria
Hoskisson, Paul (Principal Investigator)
01-Jan-2023 - 30-Jan-2026
Lost in Translation: reassessing bldA control of antibiotic biosynthesis
Hoskisson, Paul (Principal Investigator)
01-Jan-2023 - 30-Jan-2026
Understanding the mechanism and evolution of a unique viral defence system
Hoskisson, Paul (Principal Investigator)
01-Jan-2023 - 31-Jan-2025
Investigating the growth dynamics of multispecies biofilms on medical grade silicone by Mesoscopy
Baxter, Katherine (Principal Investigator) Hoskisson, Paul (Co-investigator) McConnell, Gail (Co-investigator)
14-Jan-2022 - 13-Jan-2023
Doctoral Training Partnership 2020-2021 University of Strathclyde | Salihovic, Admir
Burley, Glenn (Principal Investigator) Hoskisson, Paul (Co-investigator) Salihovic, Admir (Research Co-investigator)
01-Jan-2021 - 01-Jan-2025
Understanding genome dynamics of Streptomyces clavuligerus during industrial fermentations
Hoskisson, Paul (Principal Investigator)
01-Jan-2021 - 30-Jan-2025

More projects

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Contact

Professor Paul Hoskisson
Strathclyde Institute of Pharmacy and Biomedical Sciences

Email: paul.hoskisson@strath.ac.uk
Tel: 548 2819