Professor Paul Hoskisson

Strathclyde Institute of Pharmacy and Biomedical Sciences


Personal statement

Laboratory webpage is here

Research in my group is focussed on the synthesis of antibiotics and the evolution of bacterial pathogens, using a range of techniques from molecular biology and biochemistry through to mathematical modelling and image analysis. The bacterial genus Streptomyces is the main focus of work in my Research Group due to its industrial importance, being responsible for producing around two thirds of all commercially important antibiotics as well as numerous anti-fungal, anti-helminthic and anti-cancer drugs. 

We also have an interest in evolution of metabolism, evolution of bacterial pathogens, genomics of actinobacteria and the exploitation of amphibian proteins for biotechnology. 

We use a range of techniques to study the biology of actinobacteria including molecular genetics, protein biochemistry, genomics, microscopy, physiology, advanced spectroscopy, mathematical modeling and bioinformatics.

I was elected as a member of the Royal Society of Edinburgh Young Academy of Scotland in 2014 and a Fellow of the Royal Society of Biology (FRSB) in 2016.

I am a member of the Microbiology Society, the American Society of Microbiology, the Biochemical Society, The Royal Society of Biology and British Herpetological Society.

I am a managing editor for Antonie van Leeuwenhoek International Journal of Microbiology, and sit on the editorial board for Microbial Genomics, Frontiers in Antimicrobials, resistance and chemotherapy, Frontiers in Microbial Physiology and Metabolism, Frontiers in Synthetic Biology and Metabolism and Nature Scientific Data and Nature Scientific Reports.I am a former Editor in Chief of Microbiology Today.

I am a Fellow of the Higher Education Academy.

I am interested in the use of Social media for communication of science and you can follow on Twitter @paulhoskisson

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Sequence and origin of the Streptomyces intergenetic-conjugation helper plasmid pUZ8002
Larcombe Daniel E, Braes Robyn E, Croxford James T, Wilson James W, Figurski David H, Hoskisson Paul A
Access Microbiology Vol 6 (2024)
Phenotypic heterogeneity in Streptomyces colonies
Hoskisson Paul A, Barona-Gómez Francisco, Rozen Daniel E
Current Opinion in Microbiology Vol 78 (2024)
Microbial primer : bacterial growth kinetics
Fernández-Martínez Lorena T, Javelle Arnaud, Hoskisson Paul A
Microbiology Vol 170 (2024)
The parasitic worm product ES- 62 protects against collageninduced arthritis by resetting the gut-bone marrow axis in a microbiome-dependent manner
Harnett Margaret, Doonan James, Tarafdar Anuradha, Pineda Miguel, Duncombe-Moore Josephine, Buitrago Geraldine, Pan Piaopiao, Hoskisson Paul, Selman Colin, Harnett William
Frontiers in Tropical Diseases Vol 4 (2024)
Construction and characterisation of a structured, tuneable, and transparent 3D culture platform for soil bacteria
Rooney Liam M, Dupuy Lionel X, Hoskisson Paul A, McConnell Gail
Microbiology Vol 170 (2024)
Biological ammonium transporters : evolution and diversification
Williamson Gordon, Harris Thomas, Bizior Adriana, Hoskisson Paul Alan, Pritchard Leighton, Javelle Arnaud
FEBS Journal (2024)

More publications

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Professional Activities

BBSRC (Biotech & Biological Sciences Research Council) (External organisation)
Joint Programme Initiative on Antimicrobial Resistance (External organisation)
Investigating the fractal nature of channels within E. coli biofilms with altered cell phenotype
Investigating the influence of cell shape on intra-colony channel architecture by fractal analysis of confocal microscopy biofilm images
Aurodox – a Type III secretion system inhibitor from Streptomyces.
Chance and necessity: navigating the strain improvement fitness landscape.

More professional activities


Engineering Streptomyces bacteria for the sustainable manufacture of antibiotics
Hoskisson, Paul (Principal Investigator)
14-Jan-2024 - 13-Jan-2026
Taming of the Streptomycete: Understanding the rules of domestication in antibiotic-producing bacteria
Hoskisson, Paul (Principal Investigator)
01-Jan-2023 - 30-Jan-2026
Lost in Translation: reassessing bldA control of antibiotic biosynthesis
Hoskisson, Paul (Principal Investigator)
01-Jan-2023 - 30-Jan-2026
BIO-ART: Multiscale understanding of BIOfilms and microBIOmes in Acute Recurrent Tonsillitis (Fellowship for Catriona Douglas, NHS)
McConnell, Gail (Principal Investigator) Hoskisson, Paul (Co-investigator) Shu, Will (Co-investigator)
09-Jan-2023 - 08-Jan-2026
Understanding the mechanism and evolution of a unique viral defence system
Hoskisson, Paul (Principal Investigator)
01-Jan-2023 - 31-Jan-2025
Investigating the growth dynamics of multispecies biofilms on medical grade silicone by Mesoscopy
Baxter, Katherine (Principal Investigator) Hoskisson, Paul (Co-investigator) McConnell, Gail (Co-investigator)
14-Jan-2022 - 13-Jan-2023

More projects

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Professor Paul Hoskisson
Strathclyde Institute of Pharmacy and Biomedical Sciences

Tel: 548 2819