Professor Paul Hoskisson

Strathclyde Institute of Pharmacy and Biomedical Sciences

Personal statement

Laboratory webpage is here http://paulhoskisson.weebly.com

Research in my group is focussed on the synthesis of antibiotics and the evolution of bacterial pathogens, using a range of techniques from molecular biology and biochemistry through to mathematical modelling and image analysis. The bacterial genus Streptomyces is the main focus of work in my Research Group due to its industrial importance, being responsible for producing around two thirds of all commercially important antibiotics as well as numerous anti-fungal, anti-helminthic and anti-cancer drugs. 

We also have an interest in evolution of metabolism, evolution of bacterial pathogens, genomics of actinobacteria and the exploitation of amphibian proteins for biotechnology. 

We use a range of techniques to study the biology of actinobacteria including molecular genetics, protein biochemistry, genomics, microscopy, physiology, advanced spectroscopy, mathematical modeling and bioinformatics.

I was elected as a member of the Royal Society of Edinburgh Young Academy of Scotland in 2014 and a Fellow of the Royal Society of Biology (FRSB) in 2016.

I am a member of the Microbiology Society, the American Society of Microbiology, the Biochemical Society, The Royal Society of Biology and British Herpetological Society.

I am a managing editor for Antonie van Leeuwenhoek International Journal of Microbiology, and sit on the editorial board for Microbial Genomics, Frontiers in Antimicrobials, resistance and chemotherapy, Frontiers in Microbial Physiology and Metabolism, Frontiers in Synthetic Biology and Metabolism and Nature Scientific Data and Nature Scientific Reports.I am a former Editor in Chief of Microbiology Today.

I am a Fellow of the Higher Education Academy.

I am interested in the use of Social media for communication of science and you can follow on Twitter @paulhoskisson

Publications

Biosynthesis of aurodox, a Type III secretion system inhibitor from Streptomyces goldiniensis
McHugh Rebecca E, Munnoch John T, Braes Robyn E, McKean Iain J W, Giard Jospehine, Taladriz-Sender Andrea, Peschke Frederik, Burley Glenn A, Roe Andrew J, Hoskisson Paul A
Applied and Environmental Microbiology Vol 88 (2022)
https://doi.org/10.1128/aem.00692-22
ActinoBase : tools and protocols for researchers working on Streptomyces and other filamentous actinobacteria
Feeney Morgan Anne, Newitt Jake Terry, Addington Emily, Algora-Gallardo Lis, Allan Craig, Balis Lucas, Birke Anna S, Castaño-Espriu Laia, Charkoudian Louise K, Devine Rebecca, Gayrard Damien, Hamilton Jacob, Hennrich Oliver, Hoskisson Paul A, Keith-Baker Molly, Klein Joshua G, Kruasuwan Worarat, Mark David R, Mast Yvonne, McHugh Rebecca E, McLean Thomas C, Mohit Elmira, Munnoch John T, Murray Jordan, Noble Katie, Otani Hiroshi, Parra Jonathan, Pereira Camila F, Perry Louisa, Pintor-Escobar Linamaria, Pritchard Leighton, Prudence Samuel M M, Russell Alicia H, Schniete Jana K, Seipke Ryan F, Sélem-Mojica Nelly, Undabarrena Agustina, Vind Kristiina, van Wezel Gilles P, Wilkinson Barrie, Worsley Sarah F, Duncan Katherine R, Fernández-Martínez Lorena T, Hutchings Matthew I
Microbial Genomics Vol 8 (2022)
https://doi.org/10.1099/mgen.0.000824
A fully integrated rapid on-chip antibiotic susceptibility test - a case study for Mycobacterium smegmatis
Gorbanpoor Hahmad, Norouz Dizaji Araz, Akcakoca Iremnur, Blair Ewen O, Ozturk Yasin, Hoskisson Paul, Kocagoz Tanil, Avci Huseyin, Corrigan Damion K, Guzel Fatma Dogan
Sensors and Actuators A: Physical Vol 339 (2022)
https://doi.org/10.1016/j.sna.2022.113515
Genome sequence of the aurodox-producing bacterium Streptomyces goldiniensis ATCC 21386
McHugh Rebecca E, Munnoch John T, Roe Andrew J, Hoskisson Paul A
Access Microbiology Vol 4 (2022)
https://doi.org/10.1099/acmi.0.000358
Disruption of the mce operon from Streptomyces affects spore resistance and results in precocious germination
Addington Emily, Clark Laura, Hoskisson Paul
Microbiology Society Annual Conference 2021 (2022)
https://doi.org/10.1099/acmi.ac2021.po0266
Electrochemical antibiotic susceptibility testing – an emerging approach for fast and accurate determination of antibiotic effect in complex samples
Hannah Stuart, Domingo-Roca Roger, Hoskisson Paul A, Murphy Michael E, Corrigan Damion K
Current Opinion in Electrochemistry Vol 35 (2022)
https://doi.org/10.1016/j.coelec.2022.101033

More publications

Professional activities

Meet the Researcher- MRS 2019
Speaker
27/2/2019
Applying the Mesolens to Microbiology; Visualising Biofilm Architecture and Substructure
Contributor
13/4/2018
Generating metabolic robustness for antibiotic biosynthesis though the expansion of primary metabolism in Streptomyces
Speaker
5/3/2018
Applying the Mesolens to Microbiology; Visualising Biofilm Architecture and Substructure
Contributor
22/11/2017
Frogs, Foam and foiling antibiotic resistant infections
Speaker
10/11/2017
Generating metabolic robustness for antibiotic biosynthesis though the expansion of primary metabolism in Streptomyces
Speaker
26/10/2017

More professional activities

Projects

Investigating the growth dynamics of multispecies biofilms on medical grade silicone by Mesoscopy
BAXTER, Katherine (Principal Investigator) Hoskisson, Paul (Co-investigator) McConnell, Gail (Co-investigator)
14-Jan-2022 - 13-Jan-2023
Doctoral Training Partnership 2020-2021 University of Strathclyde | Salihovic, Admir
Burley, Glenn (Principal Investigator) Hoskisson, Paul (Co-investigator) Salihovic, Admir (Research Co-investigator)
01-Jan-2021 - 01-Jan-2025
Aversion Therapy for Bacteria: Repurposing Aurodox
Hoskisson, Paul (Principal Investigator)
01-Jan-2021 - 31-Jan-2024
Fluorous-based diagnostic platform for multiplexed diagnosis and differentiation of viral infections
Burley, Glenn (Principal Investigator) Corrigan, Damion (Co-investigator) Hoskisson, Paul (Co-investigator)
01-Jan-2021 - 31-Jan-2022
SPRINT: A SuPer-Resolution time-resolved ImagiNg and specTroscopy facility for rapid biomolecular analysis
Li, David (Principal Investigator) Chamberlain, Luke (Co-investigator) Chen, Yu (Co-investigator) Cunningham, Margaret Rose (Co-investigator) Gould, Gwyn (Co-investigator) Hoskisson, Paul (Co-investigator) McConnell, Gail (Co-investigator) Rattray, Zahra (Co-investigator) Van de Linde, Sebastian (Co-investigator)
01-Jan-2021 - 28-Jan-2023
How does the immunomodulatory parasitic worm product ES-62 rewire bone marrow cells to increase healthspan and lifespan in obesity-accelerated ageing?
Harnett, William (Principal Investigator) Hoskisson, Paul (Co-investigator)
01-Jan-2021 - 31-Jan-2024

More projects

Address

Strathclyde Institute of Pharmacy and Biomedical Sciences
Hamnett Wing

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