Professor Paul Hoskisson

Strathclyde Institute of Pharmacy and Biomedical Sciences

Personal statement

Laboratory webpage is here http://paulhoskisson.weebly.com

Research in my group is focussed on the synthesis of antibiotics and the evolution of bacterial pathogens, using a range of techniques from molecular biology and biochemistry through to mathematical modelling and image analysis. The bacterial genus Streptomyces is the main focus of work in my Research Group due to its industrial importance, being responsible for producing around two thirds of all commercially important antibiotics as well as numerous anti-fungal, anti-helminthic and anti-cancer drugs. 

We also have an interest in evolution of metabolism, evolution of bacterial pathogens, genomics of actinobacteria and the exploitation of amphibian proteins for biotechnology. 

We use a range of techniques to study the biology of actinobacteria including molecular genetics, protein biochemistry, genomics, microscopy, physiology, advanced spectroscopy, mathematical modeling and bioinformatics.

I was elected as a member of the Royal Society of Edinburgh Young Academy of Scotland in 2014 and a Fellow of the Royal Society of Biology (FRSB) in 2016.

I am a member of the Microbiology Society, the American Society of Microbiology, the Biochemical Society, The Royal Society of Biology and British Herpetological Society.

I am a managing editor for Antonie van Leeuwenhoek International Journal of Microbiology, and sit on the editorial board for Microbial Genomics, Frontiers in Antimicrobials, resistance and chemotherapy, Frontiers in Microbial Physiology and Metabolism, Frontiers in Synthetic Biology and Metabolism and Nature Scientific Data and Nature Scientific Reports.I am a former Editor in Chief of Microbiology Today.

I am a Fellow of the Higher Education Academy.

I am interested in the use of Social media for communication of science and you can follow on Twitter @paulhoskisson

Publications

A multiomic approach to defining 1 the essential genome of the globally important pathogen Corynebacterium diphtheriae
Goodall Emily C A, Atunes Camila Azevedo, Möller Jens, Sangal Vartul, Torres Von Vergel L, Gray Jessica, Cunningham Adam F, Hoskisson Paul A, Burkovski Andreas, Henderson Ian R
PLOS Genetics Vol 19 (2023)
https://doi.org/10.1371/journal.pgen.1010737
On the evolution of natural product biosynthesis
Barona-Gómez Francisco, Chevrette Marc G, Hoskisson Paul A
Advances in Microbial Physiology (2023) (2023)
Transcriptome landscapes of salt-susceptible rice cultivar IR29 associated with a plant growth promoting endophytic streptomyces
Kruasuwan Worarat, Lohmaneeratana Karan, Munnoch John T, Vongsangnak Wanwipa, Jantrasuriyarat Chatchawan, Hoskisson Paul A, Thamchaipenet Arinthip
Rice Vol 16 (2023)
https://doi.org/10.1186/s12284-023-00622-7
Rapid assessment of antibiotic susceptibility using a fully 3D-printed impedance- based biosensor
Domingo-Roca R, Lasserre P, Riordan L, Macdonald AR, Dobrea A, Duncan KR, Hannah S, Murphy M, Hoskisson PA, Corrigan DK
Biosensors and Bioelectronics X Vol 13 (2023)
https://doi.org/10.1016/j.biosx.2023.100308
Addressing multi-scale microbial challenges using the Mesolens
Rooney Liam M, Bottura Beatrice, Baxter Katherine, Amos William B, Hoskisson Paul A, McConnell Gail
Journal of Microscopy (2023)
https://doi.org/10.1111/jmi.13172
Intra-colony channel morphology in Escherichia coli biofilms is governed by nutrient availability and substrate stiffness
Bottura Beatrice, Rooney Liam M, Hoskisson Paul A, McConnell Gail
Biofilm Vol 4 (2022)
https://doi.org/10.1016/j.bioflm.2022.100084

More publications

Professional activities

Untangling the taxonomically complex genus Streptomyces to improve pangenomic analyses
Contributor
22/9/2022
Meet the Researcher- MRS 2019
Speaker
27/2/2019
Applying the Mesolens to Microbiology; Visualising Biofilm Architecture and Substructure
Contributor
13/4/2018
Generating metabolic robustness for antibiotic biosynthesis though the expansion of primary metabolism in Streptomyces
Speaker
5/3/2018
Applying the Mesolens to Microbiology; Visualising Biofilm Architecture and Substructure
Contributor
22/11/2017
Frogs, Foam and foiling antibiotic resistant infections
Speaker
10/11/2017

More professional activities

Projects

Understanding the mechanism and evolution of a unique viral defence system
Hoskisson, Paul (Principal Investigator)
01-Jan-2023 - 31-Jan-2025
Investigating the growth dynamics of multispecies biofilms on medical grade silicone by Mesoscopy
Baxter, Katherine (Principal Investigator) Hoskisson, Paul (Co-investigator) McConnell, Gail (Co-investigator)
14-Jan-2022 - 13-Jan-2023
Understanding genome dynamics of Streptomyces clavuligerus during industrial fermentations
Hoskisson, Paul (Principal Investigator)
01-Jan-2021 - 30-Jan-2025
Doctoral Training Partnership 2020-2021 University of Strathclyde | Salihovic, Admir
Burley, Glenn (Principal Investigator) Hoskisson, Paul (Co-investigator) Salihovic, Admir (Research Co-investigator)
01-Jan-2021 - 01-Jan-2025
Aversion Therapy for Bacteria: Repurposing Aurodox
Hoskisson, Paul (Principal Investigator)
01-Jan-2021 - 31-Jan-2024
Fluorous-based diagnostic platform for multiplexed diagnosis and differentiation of viral infections
Burley, Glenn (Principal Investigator) Corrigan, Damion (Co-investigator) Hoskisson, Paul (Co-investigator)
01-Jan-2021 - 31-Jan-2022

More projects

Address

Strathclyde Institute of Pharmacy and Biomedical Sciences
Hamnett Wing

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