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Dr Paul Hoskisson


Strathclyde Institute of Pharmacy and Biomedical Sciences

Personal statement

Laboratory webpage is here

Research in my group is focussed on the synthesis of antibiotics and the evolution of bacterial pathogens, using a range of techniques from molecular biology and biochemistry through to mathematical modelling and image analysis. The bacterial genus Streptomyces is the main focus of work in my Research Group due to its industrial importance, being responsible for producing around two thirds of all commercially important antibiotics as well as numerous anti-fungal, anti-helminthic and anti-cancer drugs. 

We also have an interest in evolution of metabolism, evolution of bacterial pathogens, genomics of actinobacteria and the exploitation of amphibian proteins for biotechnology. 

We use a range of techniques to study the biology of actinobacteria including molecular genetics, protein biochemistry, genomics, microscopy, physiology, advanced spectroscopy, mathematical modeling and bioinformatics.

I was elected as a member of the Royal Society of Edinburgh Young Academy of Scotland in 2014 and a Fellow of the Royal Society of Biology (FRSB) in 2016.

I am a member of the Microbiology Society, the American Society of Microbiology, the Biochemical Society, The Royal Society of Biology and British Herpetological Society.

I am a managing editor for Antonie van Leeuwenhoek International Journal of Microbiology, and sit on the editorial board for Microbial Genomics, Frontiers in Antimicrobials, resistance and chemotherapy, Frontiers in Microbial Physiology and Metabolism, Frontiers in Synthetic Biology and Metabolism and Nature Scientific Data and Nature Scientific Reports.I am a former Editor in Chief of Microbiology Today.

I am a Fellow of the Higher Education Academy.

I am interested in the use of Social media for communication of science and you can follow on Twitter @paulhoskisson


Regulation of specialised metabolites in Actinobacteria - expanding the paradigms
Hoskisson Paul A, Fernández-Martínez Lorena T.
Environmental Microbiology Reports, pp. 1-21, (2018)
Microbe profile : Corynebacterium diphtheriae - an old foe always ready to seize opportunity
Hoskisson Paul A.
Microbiology, (2018)
Expanding primary metabolism helps generate the metabolic robustness to facilitate antibiotic biosynthesis in Streptomyces
Schniete Jana K., Cruz-Morales Pablo, Selem-Mojica Nelly, Fernández-Martínez Lorena T., Hunter Iain S., Barona-Gómez Francisco, Hoskisson Paul A.
mBio Vol 9, (2018)
Complete closed genome sequence of nontoxigenic invasive Corynebacterium diphtheriae bv. mitis strain ISS 3319
Azevedo Antunes Camila, Richardson Emily J., Quick Joshua, Fuentes-Utrilla Pablo, Isom Georgia L., Goodall Emily C., Möller Jens, Hoskisson Paul A., Mattos-Guaraldi Ana Luiza, Cunningham Adam F., Loman Nicholas J., Sangal Vartul, Burkovski Andreas, Henderson Ian R.
Genome Announcements Vol 6, pp. 1-2, (2018)
The E. coli dicarboxylic acid transporters DauA act as a signal transducer by interacting with the DctA uptake system
Karinou Eleni, Hoskisson Paul A., Strecker Alexander, Unden Gottfried, Javelle Arnaud
Scientific Reports Vol 7, (2017)
Genomic analysis of endemic clones of toxigenic and non-toxigenic Corynebacterium diphtheriae in Belarus during and after the major epidemic in 1990s
Grosse-Kock Steffan, Kolodkina Valentina, Schwalbe Edward C., Blom Jochen, Burkovski Andreas, Hoskisson Paul A., Brisse Sylvain , Smith Darren, Sutcliffe Iain C., Titov Leonid, Sangal Vartul
BMC Genomics Vol 18, (2017)

more publications

Professional activities

Generating metabolic robustness for antibiotic biosynthesis though the expansion of primary metabolism in Streptomyces
Frogs, Foam and foiling antibiotic resistant infections
Generating metabolic robustness for antibiotic biosynthesis though the expansion of primary metabolism in Streptomyces
Generating metabolic robustness for antibiotic biosynthesis though the expansion of primary metabolism in Streptomyces
Generating metabolic robustness for antibiotic biosynthesis though the expansion of primary metabolism in Streptomyces
Small Talk: Communicating microbiology in the digital age

more professional activities


Can epistasis be exploited to understand industrial antibiotic production in Streptomyces
Hoskisson, Paul (Principal Investigator)
Period 19-Feb-2018 - 18-Aug-2018
MycoChip - A rapid onchip antibiotic susceptibility test for Mycobacterium tuberculosis (Newton Fund)
Corrigan, Damion (Principal Investigator) Hoskisson, Paul (Co-investigator)
Period 12-Feb-2018 - 14-Feb-2020
Microplate - shrinking culture plates onto a microchip for a rapid antibiotic susceptibility test
Corrigan, Damion (Principal Investigator) Hoskisson, Paul (Co-investigator) Shu, Will (Co-investigator)
Period 01-Sep-2017 - 31-Aug-2018
EPSRC Centre for Doctoral Training in Medical Devices and Health Technologies | Vezza, Vincent James
Corrigan, Damion (Principal Investigator) Hoskisson, Paul (Co-investigator) Vezza, Vincent James (Research Co-investigator)
Period 01-Oct-2016 - 01-Oct-2020
Microfluidic manufacturing and development of a novel clostridium difficile oral vaccine | Forbes, Neil Liam Andrew
Perrie, Yvonne (Principal Investigator) Hoskisson, Paul (Co-investigator) Forbes, Neil Liam Andrew (Research Co-investigator)
Period 01-Oct-2016 - 01-Oct-2019
Establishing an integrated biocatalytic Friedel-Crafts platform for the alkylation of aromatic small molecules | McKean, Iain
Burley, Glenn (Principal Investigator) Hoskisson, Paul (Co-investigator) McKean, Iain (Research Co-investigator)
Joint authorship of a review article.
Period 01-Oct-2015 - 01-Oct-2019

more projects


Strathclyde Institute of Pharmacy and Biomedical Sciences
Hamnett Wing John Arbuthnott Building

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