Professor Paul Hoskisson

Strathclyde Institute of Pharmacy and Biomedical Sciences

Personal statement

Laboratory webpage is here http://paulhoskisson.weebly.com

Research in my group is focussed on the synthesis of antibiotics and the evolution of bacterial pathogens, using a range of techniques from molecular biology and biochemistry through to mathematical modelling and image analysis. The bacterial genus Streptomyces is the main focus of work in my Research Group due to its industrial importance, being responsible for producing around two thirds of all commercially important antibiotics as well as numerous anti-fungal, anti-helminthic and anti-cancer drugs. 

We also have an interest in evolution of metabolism, evolution of bacterial pathogens, genomics of actinobacteria and the exploitation of amphibian proteins for biotechnology. 

We use a range of techniques to study the biology of actinobacteria including molecular genetics, protein biochemistry, genomics, microscopy, physiology, advanced spectroscopy, mathematical modeling and bioinformatics.

I was elected as a member of the Royal Society of Edinburgh Young Academy of Scotland in 2014 and a Fellow of the Royal Society of Biology (FRSB) in 2016.

I am a member of the Microbiology Society, the American Society of Microbiology, the Biochemical Society, The Royal Society of Biology and British Herpetological Society.

I am a managing editor for Antonie van Leeuwenhoek International Journal of Microbiology, and sit on the editorial board for Microbial Genomics, Frontiers in Antimicrobials, resistance and chemotherapy, Frontiers in Microbial Physiology and Metabolism, Frontiers in Synthetic Biology and Metabolism and Nature Scientific Data and Nature Scientific Reports.I am a former Editor in Chief of Microbiology Today.

I am a Fellow of the Higher Education Academy.

I am interested in the use of Social media for communication of science and you can follow on Twitter @paulhoskisson

Publications

An electrochemical SARS-CoV-2 biosensor inspired by glucose test strip manufacturing processes
Vezza Vincent J, Butterworth Adrian, Lasserre Perrine, Blair Ewen O, MacDonald Alexander, Hannah Stuart, Rinaldi Christopher, Hoskisson Paul A, Ward Andrew C, Longmuir Alistair, Setford Steven, Farmer Eoghan C W, Murphy Michael E, Corrigan Damion K
Chemical Communications (2021)
https://doi.org/10.1039/D1CC00936B
ActDES – a curated actinobacterial database for evolutionary studies
Schniete Jana K, Selem-Mojica Nelly, Birke Anna S, Cruz-Morales Pablo, Hunter Iain S, Barona-Gómez Francisco, Hoskisson Paul A
Microbial Genomics Vol 7 (2021)
https://doi.org/10.1099/mgen.0.000498
Biologically modified microelectrode sensors provide enhanced sensitivity for detection of nucleic acid sequences from Mycobacterium tuberculosis
Blair Ewen O, Hannah Stuart, Vezza Vincent, Avci Hüseyin, Kocagoz Tanil, Hoskisson Paul A, Güzel Fatma D, Corrigan Damion K
Sensors and Actuators Reports Vol 2 (2020)
https://doi.org/10.1016/j.snr.2020.100008
Intra-colony channels in E. coli function as a nutrient uptake system
Rooney Liam M, Amos William B, Hoskisson Paul A, McConnell Gail
ISME Journal Vol 14, pp. 2461-2473 (2020)
https://doi.org/10.1038/s41396-020-0700-9
Development of a rapid, antimicrobial susceptibility test for E. coli based on low-cost, screen-printed electrodes
Hannah Stuart, Dobrea Alexandra, Lasserre Perrine, Blair Ewen O, Alcorn David, Hoskisson Paul A, Corrigan Damion K
Biosensors Vol 10 (2020)
https://doi.org/10.3390/bios10110153
Cryptic or silent? The known unknowns, unknown knowns, and unknown unknowns of secondary metabolism
Hoskisson Paul A, Seipke Ryan F
mBio Vol 11 (2020)
https://doi.org/10.1128/mBio.02642-20

More publications

Professional activities

Meet the Researcher- MRS 2019
Speaker
27/2/2019
Applying the Mesolens to Microbiology; Visualising Biofilm Architecture and Substructure
Contributor
13/4/2018
Generating metabolic robustness for antibiotic biosynthesis though the expansion of primary metabolism in Streptomyces
Speaker
5/3/2018
Applying the Mesolens to Microbiology; Visualising Biofilm Architecture and Substructure
Contributor
22/11/2017
Frogs, Foam and foiling antibiotic resistant infections
Speaker
10/11/2017
Generating metabolic robustness for antibiotic biosynthesis though the expansion of primary metabolism in Streptomyces
Speaker
26/10/2017

More professional activities

Projects

Does the parasitic worm product ES-62 resolve aberrant chronic inflammation by sensing and normalising the gut microbiome and intestinal integrity?
Harnett, William (Principal Investigator) Hoskisson, Paul (Co-investigator)
01-Jan-2020 - 30-Jan-2023
GlasBioPhys: An integrated facility for the analysis of biomolecular interactions (19ALERT Mid-range equipment initiative)
Burley, Glenn (Principal Investigator) Chamberlain, Luke (Co-investigator) Faulds, Karen (Co-investigator) Hoskisson, Paul (Co-investigator)
11-Jan-2020 - 09-Jan-2021
Structural investigation of the Candida albicans/Staphylococcus aureus dual biofilm by Mesolens 3D imaging
BAXTER, Katherine (Co-investigator) Hoskisson, Paul (Principal Investigator) McConnell, Gail (Co-investigator)
01-Jan-2020 - 31-Jan-2023
Structural investigation of the Candida albicans/Staphylococcus aureus dual biofilm by Mesolens 3D imaging (Fellowship for Katherine Baxter)
Hoskisson, Paul (Principal Investigator) McConnell, Gail (Co-investigator)
01-Jan-2020 - 31-Jan-2023
Engineering biology of antibiotics (RAEng Research Chair)
Hoskisson, Paul (Principal Investigator)
01-Jan-2020 - 30-Jan-2025
Microplate High Growth Spinout Programme Phase 1
Corrigan, Damion (Principal Investigator) Hoskisson, Paul (Co-investigator)
01-Jan-2020 - 31-Jan-2022

More projects

Address

Strathclyde Institute of Pharmacy and Biomedical Sciences
Hamnett Wing

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