Professor Craig Jamieson

Pure and Applied Chemistry

Contact

Back to staff profile

Publications

A first insight into the developability of an Immunoglobulin G3 : a combined computational and experimental approach
Armstrong Georgina B, Lewis Alan, Shah Vidhi, Taylor Paul, Jamieson Craig J, Burley Glenn A, Lewis Will, Rattray Zahra
ACS Pharmacology & Translational Science (2024)
https://doi.org/10.1021/acsptsci.4c00271
One-pot oxidative amidation of aldehydes via the generation of nitrile imine intermediates
Henry Martyn C, Minty Laura, Kwok Alexander C W, Elwood Jessica M L, Foulis Adam J, Pettinger Jonathan, Jamieson Craig
Journal of Organic Chemistry Vol 89, pp. 7913-7926 (2024)
https://doi.org/10.1021/acs.joc.4c00575
A framework for the biophysical screening of antibody mutations targeting solvent-accessible hydrophobic and electrostatic patches for enhanced viscosity profiles
Armstrong Georgina B, Shah Vidhi, Sanches Paula, Patel Mitul, Casey Ricky, Jamieson Craig, Burley Glenn A, Lewis William, Rattray Zahra
Computational and Structural Biotechnology Journal Vol 23, pp. 2345-2357 (2024)
https://doi.org/10.1016/j.csbj.2024.05.041
Development of a horizontal dynamically mixed flow reactor for laboratory scale-up of photochemical Wohl–Ziegler bromination
Pratley Cassie, Shaalan Youssef, Boulton Lee, Jamieson Craig, Murphy John A, Edwards Lee J
Organic Process Research and Development Vol 28, pp. 1725-1733 (2024)
https://doi.org/10.1021/acs.oprd.3c00348
Exploiting bi-specific engagement : assessing monovalent vs bivalent binding
Duxbury Rachel, Beveridge Rebecca, Jamieson Craig, Jones David, Jones Gavin, Rattray Zahra
Immuno-oncology Summit Europe 2024 (2024)
Improving bi-specific engagement : assessing monovalent vs bivalent binding
Duxbury Rachel, Beveridge Rebecca, Jamieson Craig, Jones David, Jones Gavin, Rattray Zahra
2nd Annual GSK Biopharm Postgraduate Symposium (2024)

More publications

Back to staff profile

Research Interests

Biography

Craig Jamieson earned his BSc (Hons) in Chemistry at the University of Glasgow in 1996. His PhD studies were carried out under the direction of Professor R Ramage at the University of Edinburgh (1999).  Following postdoctoral research under the supervision of Professor S V Ley at the University of Cambridge, in 2001 he was appointed as a Principal Scientist in GlaxoSmithKline's Discovery Medicinal Chemistry group working on a range of exploratory medicinal chemistry programmes.  In 2004, Craig joined Organon Laboratories (later Merck Research Labs) as a Group Leader in the Medicinal Chemistry Department, with responsibility for hit to clincal candidate optimisation.  In August 2010, Craig was appointed as a John Anderson Research Lecturer in Chemical Biology, based in the Department of Pure and Applied Chemistry at the University of Strathclyde where he is currently a Professor in the Chemical Biology and Medicinal Chemistry Research Theme.

Research Interests

A major area of focus for our research continues to be in the Chemistry-Biology-Medicine continuum.  In this regard, we have a number of active programmes centred around hit and lead identification on disease targets and mechanisms in areas of significant societal need.  Allied to our work in the medicinal chemistry sphere, we also have a keen interest in the development of novel, enabling synthetic methodologies to enhance the armamentarium of molecule makers working in our arena.  We collaborate with groups and industrial partners locally, nationally and globally in order to effectively meet our research goals.

Professional Activities

Sequence engineering to improve syringeability of high concentration mAb formulations
Contributor
23/11/2022
Gyros Protein Technologies
Visiting researcher
1/6/2019
Almac Sciences
Visiting researcher
31/5/2019
Aldeyra Therapeutics Inc
Consultant
1/10/2018
Arc Scientific
Consultant
1/1/2016
Journal of the American Chemical Society (Journal)
Peer reviewer
1/1/2014

More professional activities

Projects

A Prosperity Partnership for the Design of Next-Generation Antibody Drug Bioconjugates (Next-Gen ADC)
Burley, Glenn (Principal Investigator) Jamieson, Craig (Co-investigator) Kerr, William (Co-investigator) Nordon, Alison (Co-investigator) Rattray, Zahra (Co-investigator) Tomkinson, Nick (Co-investigator)
15-Jan-2023 - 14-Jan-2028
Developing new bioanalytical pipelines for early-stage assessment of antibody-drug conjugate developability
Rattray, Zahra (Principal Investigator) Jamieson, Craig (Co-investigator) Jolliffe, Sophie (Research Co-investigator)
02-Jan-2023 - 01-Jan-2027
Biopharmaceuticals - Investigating immune complex formation induced by bispecific antibody engagement with soluble target antigens.
Rattray, Zahra (Principal Investigator) Jamieson, Craig (Principal Investigator) Gauntlett, Ross William (Post Grad Student)
01-Jan-2023 - 31-Jan-2027
Industrial CASE Account - University of Strathclyde 2022 | McTaggart, Eilidh
Jamieson, Craig (Principal Investigator) Burley, Glenn (Co-investigator) McTaggart, Eilidh (Research Co-investigator)
01-Jan-2023 - 01-Jan-2027
NMR-BASE: Nuclear Magnetic Resonance for Biomolecule Analysis in Supported Environments
Parkinson, John (Principal Investigator) Burley, Glenn (Co-investigator) Dufès, Christine (Co-investigator) Irving, Craig (Co-investigator) Jamieson, Craig (Co-investigator) Scott, Fraser (Co-investigator) Seib, Philipp (Co-investigator) Taladriz Sender, Andrea (Co-investigator)
01-Jan-2023 - 31-Jan-2024
Industrial CASE Account - University of Strathclyde 2022 | Jackson, Cara
Beveridge, Rebecca (Principal Investigator) Jamieson, Craig (Co-investigator) Jackson, Cara (Research Co-investigator)
01-Jan-2022 - 01-Jan-2026

More projects

Back to staff profile

Contact

Professor Craig Jamieson
Pure and Applied Chemistry

Email: craig.jamieson@strath.ac.uk
Tel: 548 4830