Dr Craig Jamieson

Reader

Pure and Applied Chemistry

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Publications

Current and emerging approaches to noncompetitive AR inhibition
Riley Christopher M, Elwood Jessica M L, Henry Martyn C, Hunter Irene, Lopez-Fernandez J Daniel, McEwan Iain J, Jamieson Craig
Medicinal Research Reviews Vol 43, pp. 1701-1747 (2023)
https://doi.org/10.1002/med.21961
Functionalized tetrazoles as latent active esters in the synthesis of amide bonds
Elwood Jessica M L, Henry Martyn C, Lopez-Fernandez J Daniel, Mowat Jenna M, Boyle Mhairi, Buist Benjamin, Livingstone Keith, Jamieson Craig
Organic Letters Vol 24, pp. 9491-9496 (2022)
https://doi.org/10.1021/acs.orglett.2c03971
Identification and optimization of a ligand-efficient benzoazepinone bromodomain and extra terminal (BET) family acetyl-lysine mimetic into the oral candidate quality molecule I-BET432
Humphreys Philip G, Anderson Niall A, Bamborough Paul, Baxter Andrew, Chung Chun-wa, Cookson Rosa, Craggs Peter D, Dalton Toryn, Fournier Julie C L, Gordon Laurie J, Gray Heather F, Gray Matthew W, Gregory Richard, Hirst David J, Jamieson Craig, Jones Katherine L, Kessedjian Hripsimee, Lugo David, McGonagle Grant, Patel Vipulkumar K, Patten Christopher, Poole Darren L, Prinjha Rab K, Ramirez-Molina Cesar, Rioja Inmaculada, Seal Gail, Stafford Kayleigh A J, Shah Rishi R, Tape Daniel, Theodoulou Natalie H, Tomlinson Laura R, Ukuser Sabri, Wall Ian D, Wellaway Natalie, White Gemma
Journal of Medicinal Chemistry Vol 65, pp. 15174-15207 (2022)
https://doi.org/10.1021/acs.jmedchem.2c01102
Author correction : Cancer-associated fibroblasts require proline synthesis by PYCR1 for the deposition of pro-tumorigenic extracellular matrix
Kay Emily J, Paterson Karla, Riera-Domingo Carla, Sumpton David, Däbritz J Henry M, Tardito Saverio, Boldrini Claudia, Hernandez-Fernaud Juan R, Athineos Dimitris, Dhayade Sandeep, Stepanova Ekaterina, Gjerga Enio, Neilson Lisa J, Lilla Sergio, Hedley Ann, Koulouras Grigorios, McGregor Grace, Jamieson Craig, Johnson Radia Marie, Park Morag, Kirschner Kristina, Miller Crispin, Kamphorst Jurre J, Loayza-Puch Fabricio, Saez-Rodriguez Julio, Mazzone Massimiliano, Blyth Karen, Zagnoni Michele, Zanivan Sara
Nature metabolism Vol 4, pp. 1084-1084 (2022)
https://doi.org/10.1038/s42255-022-00632-7
A type IV Autotaxin inhibitor ameliorates acuteliver injury and nonalcoholic steatohepatitis
Booijink Richell, Salgado-Polo Fernando, Jamieson Craig, Perrakis Anastassis, Bansal Ruchi
EMBO Molecular Medicine Vol 14 (2022)
https://doi.org/10.15252/emmm.202216333
Cancer-associated fibroblasts require proline synthesis by PYCR1 for the deposition of pro-tumorigenic extracellular matrix
Kay Emily J, Paterson Karla, Riero-Domingo Carla, Sumpton David, Däbritz J Henry M, Tardito Saverio, Boldrini Claudia, Hernandez-Fernaud Juan R, Athineos Dimitris, Dhayade Sandeep, Stepanova Ekaterina, Gjerga Enio, Neilson Lisa J, Lilla Sergio, Hedley Ann, Koulouras Grigorios, McGregor Grace, Jamieson Craig, Johnson Radia Marie, Park Morag, Kirschner Kristina, Miller Crispin, Kamphorst Jurre J, Loayza-Puch Fabricio, Saez-Rodriguez Julio, Mazzone Massimiliano, Blyth Karen, Zagnoni Michele, Zanivan Sara
Nature metabolism Vol 4, pp. 693-710 (2022)
https://doi.org/10.1038/s42255-022-00582-0

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Research Interests

Biography

Craig Jamieson earned his BSc (Hons) in Chemistry at the University of Glasgow in 1996. His PhD studies were carried out under the direction of Professor R Ramage at the University of Edinburgh (1999).  Following postdoctoral research under the supervision of Professor S V Ley at the University of Cambridge, in 2001 he was appointed as a Principal Scientist in GlaxoSmithKline's Discovery Medicinal Chemistry group working on a range of exploratory medicinal chemistry programmes.  In 2004, Dr Jamieson joined Organon Laboratories (later Merck Research Labs) as a Group Leader in the Medicinal Chemistry Department, with responsibility for hit to clincal candidate optimisation.  In August 2010 he was appointed as a John Anderson Research Lecturer in Chemical Biology, based in the Department of Pure and Applied Chemistry at the University of Strathclyde.

Research Interests

A major area of focus for our research continues to be in the Chemistry-Biology-Medicine continuum.  In this regard, we have a number of active programmes centred around hit and lead identification on disease targets and mechanisms in areas of significant societal need, particularly in diseases of ageing.  Allied to our work in the medicinal chemistry sphere, we also have a keen interest in the development of novel, enabling synthetic methodologies to enhance the armamentarium of molecule makers working in our arena.  We collaborate with groups and industrial partners locally, nationally and globally in order to effectively meet our research goals.

Professional Activities

Sequence engineering to improve syringeability of high concentration mAb formulations
Contributor
23/11/2022
Gyros Protein Technologies
Visiting researcher
1/6/2019
Almac Sciences
Visiting researcher
31/5/2019
Aldeyra Therapeutics Inc
Consultant
1/10/2018
Arc Scientific
Consultant
1/1/2016
Science Advances (Journal)
Peer reviewer
1/1/2014

More professional activities

Projects

Industrial CASE Account - University of Strathclyde 2022 | McTaggart, Eilidh
Jamieson, Craig (Principal Investigator) Burley, Glenn (Co-investigator) McTaggart, Eilidh (Research Co-investigator)
01-Jan-2023 - 01-Jan-2027
NMR-BASE: Nuclear Magnetic Resonance for Biomolecule Analysis in Supported Environments
Parkinson, John (Principal Investigator) Burley, Glenn (Co-investigator) Dufès, Christine (Co-investigator) Irving, Craig (Co-investigator) Jamieson, Craig (Co-investigator) Scott, Fraser (Co-investigator) Seib, Philipp (Co-investigator) Taladriz Sender, Andrea (Co-investigator)
01-Jan-2023 - 31-Jan-2024
Industrial CASE Account - University of Strathclyde 2022 | Jackson, Cara
Beveridge, Rebecca (Principal Investigator) Jamieson, Craig (Co-investigator) Jackson, Cara (Research Co-investigator)
01-Jan-2022 - 01-Jan-2026
Industrial CASE Account - University of Strathclyde 2021 | Powell, Daniel
Tomkinson, Nick (Principal Investigator) Jamieson, Craig (Co-investigator) Powell, Daniel (Research Co-investigator)
01-Jan-2022 - 01-Jan-2026
Development of a new antibody drug conjugate linker
Jamieson, Craig (Principal Investigator)
01-Jan-2021 - 31-Jan-2025
Identifying New Drugs for the Treatment of Castrate Resistant Prostate Cancer
Jamieson, Craig (Principal Investigator)
Identifying New Drugs for the Treatment of Castrate Resistant Prostate Cancer: Targeting the Achilles' Heel of the Androgen Receptor
01-Jan-2020 - 31-Jan-2023

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Contact

Dr Craig Jamieson
Reader
Pure and Applied Chemistry

Email: craig.jamieson@strath.ac.uk
Tel: 548 4830