Dr Charles Kennedy

Academic Visitor

Strathclyde Institute of Pharmacy and Biomedical Sciences

Personal statement

Dr Charles Kennedy obtained a B.Sc. Honours in Pharmacology from the University of Aberdeen then a PhD in Pharmacology from University College London where he worked with Professor Geoffrey Burnstock, FRS. Following a postdoctoral position at Michigan State University in America he was a Beit Research Memorial Fellow at the University of Cambridge before joining the lecturing staff at Strathclyde.

Charles is a Fellow of the British Pharmacological Society and represents SIPBS on the society's Committee of Heads of Pharmacology. He is currently an editor of the British Journal of Pharmacology and Autonomic Neuroscience: Basic & Clinical and is on the editorial board of Purinergic Signalling and Automatic & Autocoid Pharmacology. He also chairs the IUPHAR P2X receptor nomenclature sub-committee and is a member of the IUPHAR P2Y receptor nomenclature sub-committee. In addition he has acted as the external examiner of undergraduate degrees at the Universities of Edinburgh, Nottingham and Surrey.

Our research focuses on the functions of ATP and the related nucleotides ADP, UTP and UDP, when acting through the P2X and P2Y nucleotide receptors. These are dynamic research areas with substantial therapeutic implications in areas such as chronic pain, control of blood pressure and urinary bladder dysfunction, and to which we have made significant contributions. We use a range of experimental techniques, including whole cell patch clamp electophysiology, intracellular calcium ion-imaging, molecular biology and organ bath pharmacology on whole tissues dissociated cells and cloned receptors. The lab has an industrious, but friendly atmosphere and comes complete with CD player and digital radio.

Publications

The concise guide to pharmacology 2021/22 : G protein‐coupled receptors
Alexander Stephen PH, Christopoulos Arthur, Davenport Anthony P, Kelly Eamonn, Mathie Alistair, Peters John A, Veale Emma L, Armstrong Jane F, Faccenda Elena, Harding Simon D, Pawson Adam J, Southan Christopher, Davies Jamie A, Abbracchio Maria Pia, Alexander Wayne, Al‐hosaini Khaled, Bäck Magnus, Barnes Nicholas M, Bathgate Ross, Beaulieu Jean‐Martin, Bernstein Kenneth E, Bettler Bernhard, Birdsall Nigel JM, Blaho Victoria, Boulay Francois, Bousquet Corinne, Bräuner‐Osborne Hans, Burnstock Geoffrey, Caló Girolamo, Castaño Justo P, Catt Kevin J, Ceruti Stefania, Chazot Paul, Chiang Nan, Chini Bice, Chun Jerold, Cianciulli Antonia, Civelli Olivier, Clapp Lucie H, Couture Réjean, Csaba Zsolt, Dahlgren Claes, Dent Gordon, Singh Khuraijam Dhanachandra, Douglas Steven D, Dournaud Pascal, Eguchi Satoru, Escher Emanuel, Filardo Edward J, Fong Tung, Fumagalli Marta, Gainetdinov Raul R, Gasparo Marc de, Gerard Craig, Gershengorn Marvin, Gobeil Fernand, Goodfriend Theodore L, Goudet Cyril, Gregory Karen J, Gundlach Andrew L, Hamann Jörg, Hanson Julien, Hauger Richard L, Hay Debbie L, Heinemann Akos, Hollenberg Morley D, Holliday Nicholas D, Horiuchi Mastgugu, Hoyer Daniel, Hunyady László, Husain Ahsan, IJzerman Adriaan P, Inagami Tadashi, Jacobson Kenneth A, Jensen Robert T, Jockers Ralf, Jonnalagadda Deepa, Karnik Sadashiva, Kaupmann Klemens, Kemp Jacqueline, Kennedy Charles, Kihara Yasuyuki, Kitazawa Takio, Kozielewicz Pawel, Kreienkamp Hans‐Jürgen, Kukkonen Jyrki P, Langenhan Tobias, Leach Katie, Lecca Davide, Lee John D, Leeman Susan E, Leprince Jérôme, Li Xaria X, Williams Tom Lloyd, Lolait Stephen J, Lupp Amelie, Macrae Robyn, Maguire Janet, Mazella Jean, McArdle Craig A, Melmed Shlomo, Michel Martin C, Miller Laurence J, Mitolo Vincenzo, Mouillac Bernard, Müller Christa E, Murphy Philip, Nahon Jean‐Louis, Ngo Tony, Norel Xavier, Nyimanu Duuamene, O’Carroll Anne‐Marie, Offermanns Stefan, Panaro Maria Antonietta, Parmentier Marc, Pertwee Roger G, Pin Jean‐Philippe, Prossnitz Eric R, Quinn Mark, Ramachandran Rithwik, Ray Manisha, Reinscheid Rainer K, Rondard Philippe, Rovati G Enrico, Ruzza Chiara, Sanger Gareth J, Schöneberg Torsten, Schulte Gunnar, Schulz Stefan, Segaloff Deborah L, Serhan Charles N, Stoddart Leigh A, Sugimoto Yukihiko, Summers Roger, Tan Valerie P, Thal David, Thomas Walter (Wally), Timmermans Pieter B M W M, Tirupula Kalyan, Tulipano Giovanni, Unal Hamiyet, Unger Thomas, Valant Celine, Vanderheyden Patrick, Vaudry David, Vaudry Hubert, Vilardaga Jean‐Pierre, Walker Christopher S, Wang Ji Ming, Ward Donald T, Wester Hans‐Jürgen, Willars Gary B, Woodruff Trent M, Yao Chengcan, Ye Richard D
British Journal of Pharmacology Vol 178, pp. S27-S156 (2021)
https://doi.org/10.1111/bph.15538
The concise guide to pharmacology 2021/22 : ion channels
Alexander Stephen PH, Mathie Alistair, Peters John A, Veale Emma L, Striessnig Jörg, Kelly Eamonn, Armstrong Jane F, Faccenda Elena, Harding Simon D, Pawson Adam J, Southan Christopher, Davies Jamie A, Aldrich Richard W, Attali Bernard, Baggetta Austin M, Becirovic Elvir, Biel Martin, Bill Roslyn M, Catterall William A, Conner Alex C, Davies Paul, Delling Markus, Virgilio Francesco Di, Falzoni Simonetta, Fenske Stefanie, George Chandy, Goldstein Steve A N, Grissmer Stephan, Ha Kotdaji, Hammelmann Verena, Hanukoglu Israel, Jarvis Mike, Jensen Anders A, Kaczmarek Leonard K, Kellenberger Stephan, Kennedy Charles, King Brian, Kitchen Philip, Lynch Joseph W, Perez‐Reyes Edward, Plant Leigh D, Rash Lachlan, Ren Dejian, Salman Mootaz M, Sivilotti Lucia G, Smart Trevor G, Snutch Terrance P, Tian Jinbin, Trimmer James S, Van den Eynde Charlotte, Vriens Joris, Wei Aguan D, Winn Brenda T, Wulff Heike, Xu Haoxing, Yue Lixia, Zhang Xiaoli, Zhu Michael
British Journal of Pharmacology Vol 178, pp. S157-S245 (2021)
https://doi.org/10.1111/bph.15539
ATP as a cotransmitter in sympathetic and parasympathetic nerves - another Burnstock legacy
Kennedy Charles
Autonomic Neuroscience: Basic and Clinical Vol 235 (2021)
https://doi.org/10.1016/j.autneu.2021.102860
Different responses of the blockade of the P2Y1 receptor with BPTU in human and porcine intestinal tissues and in cell cultures
Traserra Sara, Barber Claudia, MacInnes Jane, Relea Lucia, MacPherson Lewis C, Cunningham Margaret R, Vergara Patri, Accarino Anna, Kennedy Charles, Jimenez Marcel
Neurogastroenterology and Motility Vol 33 (2021)
https://doi.org/10.1111/nmo.14101
The P2Y/P2X divide : how it began
Kennedy Charles
Biochemical Pharmacology Vol 187 (2021)
https://doi.org/10.1016/j.bcp.2021.114408
That was then, this is now : the development of our knowledge and understanding of P2 receptor subtypes
Kennedy Charles
Purinergic Signalling Vol 17, pp. 9-23 (2021)
https://doi.org/10.1007/s11302-021-09763-0

More publications

Professional activities

Pharmacology 2014
Participant
16/12/2014
Glasgow Neuroscience Day, Glasgow, UK.
Participant
2014
5th BPS Focused Meeting on Cell Signalling
Participant
2014
PhD External Examiner
External Examiner
2014
PhD External Examiner
External Examiner
2013
British Journal of Pharmacology (Journal)
Editor
2013

More professional activities

Projects

Inhibitory purinergic signalling in vascular smooth muscle and its alteration in hypertensio
MacMillan, Debbi (Principal Investigator) Kennedy, Charles (Co-investigator) McCarron, John (Co-investigator)
07-Jan-2011 - 06-Jan-2013
The effects of Chinese traditional medicines on P2X receptors in sensory neurones
Kennedy, Charles (Principal Investigator)
01-Jan-2005 - 30-Jan-2007
SIGNALLING MECHANISMS UNDERLYING P2Y RECEPTOR-MEDIATED VASOCONSTRICTION IN PULMONARY ARTERIES
Kennedy, Charles (Principal Investigator)
01-Jan-2004 - 30-Jan-2008

More projects

Address

Strathclyde Institute of Pharmacy and Biomedical Sciences

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