Dr Lewis MacKenzie
Strathclyde Chancellor's Fellow
Pure and Applied Chemistry
Personal statement
I am a Chancellor's Fellow in the Department of Pure and Applied Chemistry, leading a small highly-focused research team. Our research primarily focuses on the development of photonic upconversion nanosensors for biophotonics applications, particularly biosensing, and photodynamic therapies. My background is interdisciplinary, and I am also interested in biophotonics, imaging, spectroscopy, microscopy, circularly polarised luminescence for chiral molecules, optical instrumentation, and science communication. I can offer project opportunities for masters-level and PhD students. Please email me for details. Updates can be found at these links: https://pureportal.strath.ac.uk/en/persons/lewis-mackenzie www.lewismackenzie.science
Area of Expertise
Upconversion nanoparticles, nanosensors, biophotonics, blood oximetry, tissue optics, imaging, optical instrumentation, spectroscopy, chiral spectroscopy, circularly polarised luminescence (CPL), science communication and new media.
Prize And Awards
- Postgraduate Course in Science Communication. Invited lecture.
- Recipient
- 9/2020
- Institute of Physics, 3 Minute Wonder, North East England Heat Winner
- Recipient
- 11/2019
- BBSRC Discovery Fellowship
- Recipient
- 2019
- ‘ACTION for Impact’ Pitch Competition Runner Up.
- Recipient
- 2019
- The Hunter-Cumming Postgraduate Prize for Outreach
- Recipient
- 2015
- Famelab Scotland Winner
- Recipient
- 2015
Qualifications
Ph.D. 2016. School of Physics and Astronomy, University of Glasgow. Thesis title: 'In vivo oximetry using multispectral imaging'. Supervisor: Prof. Andy Harvey.
M.Sc. Astrophysics. 2012. School of Physics and Astronomy, University of Glasgow.
B.Sc. (Hons). Physics and Astronomy. 2011. School of Physics and Astronomy, University of Glasgow.
Publications
- Influence of polyvinylpyrrolidone (PVP) in the synthesis of luminescent NaYF4:Yb,Er upconversion nanoparticles
- Birch Ross, Bruckbauer Jochen, Gajewska Marta, Cios Grzegorz, Pal Robert, MacKenzie Lewis E
- Methods and Applications in Fluorescence Vol 11 (2023)
- https://doi.org/10.1088/2050-6120/acd837
- Synthesis and structural diversification of circularly polarised luminescence active, helically chiral, "confused" N,N,O,C‐BODIPYs**
- Clarke Rebecca G, Weatherston Jake, Taj-Aldeen Rafid A, Waddell Paul G, McFarlane William, Penfold Thomas J, Bogaerts Jonathan, MacKenzie Lewis E, Herrebout Wouter, Pal Robert, Hall Michael J
- ChemPhotoChem (2022)
- https://doi.org/10.1002/cptc.202200194
- Upconversion nanoparticles (UCNPs)produced via the modest-temperature open-air PVP assisted route : tuning morphology and optical emission
- MacKenzie Lewis
- Methods and Application of Fluorescence 2022 (2022)
- Upconversion nanoparticles produced via the modest-temperature open-air PVP assisted route : tuning morphology, crystal structure, and emission properties
- MacKenzie Lewis
- Methods and Application of Fluorescence 2022 (2022)
- Circularly polarised luminescence in an RNA-based homochiral, self-repairing, coordination polymer hydrogel
- El-Zubir Osama, Rojas Martinez Pablo, Dura Gema, Al-Mahamad Lamia LG, Pope Thomas, Penfold Thomas J, MacKenzie Lewis E, Pal Robert, Mosely Jackie A, Cucinotta Fabio, McGarry Liam F, Horrocks Benjamin R, Houlton Andrew
- Journal of Materials Chemistry. C Vol 10, pp. 7329-7335 (2022)
- https://doi.org/10.1039/D2TC00366J
- Lanthanide luminescence from supramolecular hydrogels consisting of bio-conjugated picolinic-acid-based guanosine quadruplexes
- Kotova Oxana, O'Reilly Ciaran, Barwich Sebastian T, MacKenzie Lewis E, Lynes Amy D, Savyasachi Aramballi J, Ruether Manuel, Pal Robert, Möbius Matthias E, Gunnlaugsson Thorfinnur
- Chem Vol 8, pp. 1395-1414 (2022)
- https://doi.org/10.1016/j.chempr.2022.01.015
Research Interests
The MacKenzie NanoBioPhotonics group currently focus on these interdisciplinary research themes:
- Upconversion nanoparticles: synthesis, design, and functionalization.
- Nanobiosensing: oxygen measurement in blood, cells, and tissue.
- Applied optics: imaging and spectroscopy
- Quantitative science communication: science podcast and chemistry YouTube channels
For a detailed breakdown, please visit:
https://mackenzie-lab.org/research-areas
Professional Activities
- Keeping it simple? Straight-forward synthesis of upconversion nanoparticles: under-studied methods and high-safety autoclave synthesis
- Speaker
- 23/8/2023
- Reflections on a BBSRC Discovery Fellowship (2020 – 2023)
- Speaker
- 29/6/2023
- PhD student year 2 progression viva
- Examiner
- 5/5/2023
- Jose Marques-Hueso
- Host
- 5/2023
- PhD viva convenor (internal: University of Strathclyde)
- Examiner
- 21/2/2023
- Examination of Level 4 B.Sc. literature review theses
- Examiner
- 2023
Projects
- BRAINS Strathclyde Centre for Doctoral Training
- MacKenzie, Lewis (Principal Investigator) Childs, Peter (Principal Investigator) Witte, Kimia (Principal Investigator) Jimenez, Melanie (Principal Investigator) Chow, Shiao (Principal Investigator) Fu, Ying (Principal Investigator) Gomez-Roman, Natividad (Principal Investigator) Fazio, Mariana (Principal Investigator) Reid, Andrew Baxter (Principal Investigator)
- Centre for Doctoral Training in Bridging Research and Advancements in Neurological Sciences (BRAINS). First cohort of PhD students starting autumn 2023.
- 01-Jan-2023
- Versatile high-capacity high-speed benchtop centrifuge for multiple users
- MacKenzie, Lewis (Principal Investigator)
- a modern high speed refrigerated centrifuge with interchangeable carbon fibre rotors (up to 15 year lifespan) to provide for a wide variety of users applications, including 50 mL conical tubes, 15 mL conical tubes, 1.5 -2 mL Eppendorf tubes, and multi-well microplates. Max relative centrifugal force (RCF) up to 25,830 times gravity (Xg). Includes touch screen controls, quick rotor change features, self-diagnostic features, energy saving design, and advanced ergonomic features to meet the needs of multiple users.
- 01-Jan-2022 - 01-Jan-2023
- Functional nanoparticle constructs for biosensing: optimised core synthesis, mesoporous shell formation, and dye-loading.
- MacKenzie, Lewis (Principal Investigator)
- E21-5833576777
- 01-Jan-2022 - 01-Jan-2023
- Functional nanoparticle constructs for biosensing: optimised core synthesis, mesoporous shell formation, and dye-loading (Research Enablement Grant)
- MacKenzie, Lewis (Principal Investigator)
- 01-Jan-2022 - 31-Jan-2023
- EPSRC Impact Acceleration Account (IAA) - New Organisation Engagement Award: Recombinant protein for advanced nanoparticle biosensors
- MacKenzie, Lewis (Principal Investigator)
- 01-Jan-2022 - 01-Jan-2023
- University of Strathclyde: Sustainability Incentive Fund award
- MacKenzie, Lewis (Principal Investigator)
- 02-Jan-2022 - 01-Jan-2022
Contact
Dr
Lewis
MacKenzie
Strathclyde Chancellor's Fellow
Pure and Applied Chemistry
Email: l.mackenzie@strath.ac.uk
Tel: 444 7069