Dr Michelle MacLean

Senior Lecturer

Electronic and Electrical Engineering

Personal statement

I’m a Senior Lecturer in the Departments of Electronic & Electrical Engineering and Biomedical Engineering. 

My research is concerned with microbial infection control, and the development of novel disinfection and sterilisation technologies for public health applications, with particular focus on healthcare-associated infections (HAI) – the most frequent adverse event in health-care delivery worldwide, with hundreds of millions of patients affected annually.  

My major research focus has been on the fundamental antimicrobial effects of violet-blue light and it's development as a cutting-edge decontamination technology for a range of infection control applications.

I have a highly interdisciplinary background, with a BSc in Immunology and Microbiology (2002), and a PhD focused on the interdisciplinary development of UV and visible-light for sterilisation and infection control applications (2006), which I conducted at The Robertson Trust Laboratory for Electronic Sterilisation Technologies (ROLEST), at Strathclyde.  After completion of my PhD I continued my research at ROLEST where I worked as a Research Fellow.  In 2014, I was appointed as a Lecturer through a Strathclyde Chancellors Fellowship, and I was promoted to Senior Lecturer in 2017.  I have more than 70 publications, including journals, conference proceedings and presentations at scientific and medical conferences, and also have a growing IP portfolio.

Publications

Continuous monitoring of aerial bioburden within intensive care isolation rooms and identification of 'high risk' activities
Dougall LR, Booth MG, Khoo E, Hood H, MacGregor SJ, Anderson JG, Timoshkin IV, MacLean M
Journal of Hospital Infection Vol 103, pp. 185-192 (2019)
https://doi.org/10.1016/j.jhin.2019.05.010
A single-step fabrication approach for development of antimicrobial surfaces
Cai Yukui, Luo Xichun, MacLean Michelle, Qin Yi, Duxbury Mark, Ding Fei
Journal of Materials Processing Technology Vol 271, pp. 249-260 (2019)
https://doi.org/10.1016/j.jmatprotec.2019.04.012
Proceedings of the Food and Drug Administration public workshop on pathogen reduction technologies for blood safety 2018 (Commentary, p. 3026)
Atreya Chintamani, Glynn Simone, Busch Michael, Kleinman Steve, Snyder Edward, Rutter Sara, AuBuchon James, Flegel Willy, Reeve David, Divine Dana, Cohn Claudia, Custer Brian, Goodrich Raymond, Benjamin Richard J, Razatos Anna, Cancelas Jose, Wagner Stephen, MacLean Michelle, Gelderman Monique, Cap Andrew, Ness Paul
, pp. 3002-3025 (2019)
https://doi.org/10.1111/trf.15344
Biodegradable polymer drug delivery technology to prevent implanted medical device infection
Fraser Justine, MacLean Michelle, McCormick Christopher
Healthcare Infection Society (HIS) Conference 2018 (2018)
Investigating the variability of airborne bacteria in a hospital Intensive Care Unit over a 24 hour period
Dougall L, Booth MG, Khoo E, Hood H, MacGregor SJ, Anderson JG, MacLean M
Healthcare Infection Society (HIS) Conference 2018 (2018)
A local drug delivery technology to prevent implant infections
Fraser Justine, MacLean Michelle, McCormick Christopher
BioMedEng18 (2018)

more publications

Teaching

I teach on a variety of modules in the Biomedical Engineering Department:

BE919 Research Methodology

BE428 Research Methods in Biomedical Engineering

BE207 Human Cell Biology 2

BE915 Medical Science for Engineering (Haematology and Immunology lectures)

BE101 Biomedical Engineering (sterilisation of devices lecture)

BE901 Regenerative Medicine & Tissue Engineering (sterilisation and decontamination lecture)

I also supervise a range of interdisciplinary students (EEE, BME, SIPBS) for their undergraduate and postgraduate research projects.

Research interests

I am based in The Robertson Trust Laboratory for Electronic Sterilisation Technologies (ROLEST), in the Department of Electronic & Electrical Engineering, and my research is focused on the development of novel disinfection and infection control intervention technologies for public health applications, including prevention of healthcare and food/waterborne infections.

The majority of my research to date has focused on investigations into the fundamental antimicrobial effects of 405 nm high-intensity narrow-spectrum (HINS) light.  Research has focused on determining antimicrobial sensitivity, wavelength sensitivity and the mechanism of inactivation.  Much work has been focused on establishing the effects of this antimicrobial light against key pathogens including MRSA and Clostridium difficile, and I am involved in the investigation and development of this light technology for a range of disinfection applications. 

One such example of this is the development of the HINS-light Environmental Decontamination System (EDS), a novel visible light system for continuous disinfection of occupied environments such as hospital isolation rooms.  This research project was awarded the Times Higher Education Award for ‘Research Project of the Year’ in 2011.   

I am also involved in the development of a number of other electro-technologies for development towards disinfection and sterilisation applications, including ultraviolet light, pulsed electric fields, oxidative corona and plasma technologies, and ozone.

Professional activities

PhD External Examiner
External Examiner
11/1/2017

more professional activities

Projects

Doctoral Training Partnership 2018-19 University of Strathclyde | Sinclair, Lucy
MacLean, Michelle (Principal Investigator) MacGregor, Scott (Co-investigator) Sinclair, Lucy (Research Co-investigator)
01-Jan-2019 - 01-Jan-2023
PhD studentship - electrochemical biosensors for diagnosis of drug resistant infections
Corrigan, Damion (Principal Investigator) MacLean, Michelle (Co-investigator) Butterworth, Adrian (Post Grad Student)
01-Jan-2017 - 30-Jan-2020
IAA: Antimicrobial control of bacterial contamination in aquaculture hatcheries
MacLean, Michelle (Principal Investigator)
01-Jan-2017 - 30-Jan-2018
Development of Antimicrobial Blue light as a Pathogen Reduction Technology for Transfusion Medicine
MacLean, Michelle (Principal Investigator)
01-Jan-2017 - 31-Jan-2020
Development of antimicrobial 405nm HINS-light for control of bacterial populations in aquaculture hatcheries
MacLean, Michelle (Principal Investigator)
01-Jan-2017 - 31-Jan-2020
Drug-eluting technologies
McCormick, Christopher (Principal Investigator) MacLean, Michelle (Co-investigator)
01-Jan-2016 - 30-Jan-2020

more projects

Address

Electronic and Electrical Engineering
Royal College Building

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