Dr Michelle Maclean
Senior Lecturer
Electronic and Electrical Engineering
Area of Expertise
- applied microbiology
- microbial inactivation
- decontamination and sterilisation
- infection control
Prize And Awards
- Research Project of the Year
- Recipient
- 2011
Publications
- The antibacterial efficacy of far-UVC light : a combined-method study exploring the effects of experimental and bacterial variables on dose-response
- Griffin David T, Gourlay Terence, Maclean Michelle
- Pathogens Vol 13 (2024)
- https://doi.org/10.3390/pathogens13080698
- Microbial reduction of prebagged human plasma using 405nm light and its effects on coagulation factors
- Stewart Caitlin F, McGoldrick Preston, Anderson John G, MacGregor Scott J, Atreya Chintamani D, Maclean Michelle
- AMB Express Vol 14 (2024)
- https://doi.org/10.1186/s13568-024-01725-0
- Human platelet concentrates treated with microbicidal 405 nm light retain hemostasis activity
- Jackson Joseph W, Kaldhone Pravin R, Parunov Leonid A, Stewart Caitlin F, Anderson John G, MacGregor Scott J, Maclean Michelle, Atreya Chintamani D
- Journal of Photochemistry and Photobiology B: Biology Vol 255, pp. 112922 (2024)
- https://doi.org/10.1016/j.jphotobiol.2024.112922
- Smartphone-based optical sectioning (SOS) microscopy with a telecentric design for fluorescence imaging
- Jiao Ziao, Pan Mingliang, Yousaf Khadija, Doveiko Daniel, Maclean Michelle, Griffin David, Chen Yu, Li David Day Uei
- Journal of Microscopy (2024)
- https://doi.org/10.1111/jmi.13334
- Enhanced antimicrobial efficacy and energy efficiency of low irradiance 405-nm light for bacterial decontamination
- Sinclair Lucy G, Anderson John G, MacGregor Scott J, Maclean Michelle
- Archives of Microbiology Vol 206 (2024)
- https://doi.org/10.1007/s00203-024-03999-1
- A many-shells model for cell transmembrane potentials for pulsed electric field applications
- Wong Timothy, Timoshkin Igor, MacGregor Scott, Wilson Mark, Given Martin, Maclean Michelle
- IEEE Transactions on Plasma Science Vol 52, pp. 1775-1786 (2024)
- https://doi.org/10.1109/TPS.2024.3395761
Teaching
I teach on a variety of modules in the Biomedical Engineering Department:
BE919 Research Methodology
BE428 Research Methods in Biomedical Engineering
BE207 Human Cell Biology 2
BE915 Medical Science for Engineering (Haematology and Immunology lectures)
BE101 Biomedical Engineering (sterilisation of devices lecture)
BE901 Regenerative Medicine & Tissue Engineering (sterilisation and decontamination lecture)
I also supervise a range of interdisciplinary students (EEE, BME, SIPBS) for their undergraduate and postgraduate research projects.
Research Interests
I am based in The Robertson Trust Laboratory for Electronic Sterilisation Technologies (ROLEST), in the Department of Electronic & Electrical Engineering, and my research is focused on the development of novel disinfection and infection control intervention technologies for public health applications, including prevention of healthcare and food/waterborne infections.
The majority of my research to date has focused on investigations into the fundamental antimicrobial effects of 405 nm high-intensity narrow-spectrum (HINS) light. Research has focused on determining antimicrobial sensitivity, wavelength sensitivity and the mechanism of inactivation. Much work has been focused on establishing the effects of this antimicrobial light against key pathogens including MRSA and Clostridium difficile, and I am involved in the investigation and development of this light technology for a range of disinfection applications.
One such example of this is the development of the HINS-light Environmental Decontamination System (EDS), a novel visible light system for continuous disinfection of occupied environments such as hospital isolation rooms. This research project was awarded the Times Higher Education Award for ‘Research Project of the Year’ in 2011.
I am also involved in the development of a number of other electro-technologies for development towards disinfection and sterilisation applications, including ultraviolet light, pulsed electric fields, oxidative corona and plasma technologies, and ozone.
Professional Activities
- PhD External Examiner
- External Examiner
- 11/1/2017
Projects
- EPSRC IAA: Harnessing the Power of Violet-Blue Light for Pathogen Reduction of Blood Transfusion Products
- Maclean, Michelle (Co-investigator)
- 01-Apr-2022 - 31-Mar-2026
- KE Income - £30,000 (21/22): Maltani, South Korea [HINS-light Environmental Decontamination System]
- Maclean, Michelle (Co-investigator) MacGregor, Scott (Co-investigator) Anderson, John (Co-investigator) Woolsey, Gerry (Co-investigator)
- 01-Jul-2021 - 30-Jun-2022
- KE Income - £5,000 (21/22): Linea Lighting, Italy [HINS-light Environmental Decontamination System]
- MacGregor, Scott (Co-investigator) Maclean, Michelle (Co-investigator) Anderson, John (Co-investigator) Woolsey, Gerry (Co-investigator)
- 01-Jul-2021 - 30-Jun-2022
- KE Income - £77,190 (21/22): Hubbell Lighting, USA [HINS-light Environmental Decontamination System]
- MacGregor, Scott (Co-investigator) Maclean, Michelle (Co-investigator) Anderson, John (Co-investigator) Woolsey, Gerry (Co-investigator)
- 01-Jul-2021 - 30-Jun-2022
- KE Income - £366,394 (21/22): Kenall Lighting, USA [HINS-light Environmental Decontamination System]
- MacGregor, Scott (Co-investigator) Maclean, Michelle (Co-investigator) Anderson, John (Co-investigator) Woolsey, Gerry (Co-investigator)
- 01-Jul-2021 - 30-Jun-2022
- KE Income - £327 (21/22): Pinnacle Lighting, USA [HINS-light Environmental Decontamination System]
- MacGregor, Scott (Co-investigator) Maclean, Michelle (Co-investigator) Anderson, John (Co-investigator) Woolsey, Gerry (Co-investigator)
- 01-Jul-2021 - 30-Jun-2022
Contact
Dr
Michelle
Maclean
Senior Lecturer
Electronic and Electrical Engineering
Email: michelle.maclean@strath.ac.uk
Tel: 548 2891