Dr Iain Oswald

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Strathclyde Institute of Pharmacy and Biomedical Sciences

Personal statement

Iain D.H. Oswald graduated from the University of Edinburgh (2001) and remained there in the group of Professor Simon Parsons to study hydrogen-bonding patterns and co-crystallisation as part of his PhD. Fortunately, this research expanded to investigate the effects of high pressure which allowed him the opportunity to work at the European Synchrotron Radiation Facility in Grenoble. In 2004 he left for Grenoble where he became a postdoctoral researcher on the high pressure beamline (ID27). In 2006, he returned to Edinburgh to join the group of Colin R. Pulham and started a fellowship position funded by the Leverhulme Trust.

In 2009, Iain started his post at SIPBS as a Lecturer in Pharmaceutics and is interested and has been awarded funding in the areas of co-crystallisation of pharmaceutical materials at high pressure (EPSRC Early Career Fellowship, 2016-2021) and polymorphism and polymerisation of monomeric materials (Leverhulme Trust 2012-2015). 

Iain has contributed to the MPharm program as the 4th Year Co-ordinator (2012-2016) and has been an integral part of the redevelopment of the MPharm curriculum.  He was class coordinator for the 2nd year class Pharmaceutics (2013-2016) and for the Year 2 class Normal Function of the gastrointestinal tract (2012-2016).  Students in the 4th year of study will be able to work with Iain on research associated with pharmaceutical products in the solid state. His teaching activities extend to postgraduate degrees in the MRes Drug Delivery Systems and MSc Pharmaceutical Analysis course.

He was a member of the ESPRC Early Career Forum in Manufacturing from 2016-2020. The Forum is an excellent way to engage with others at a similar stage.  It seeks to engage with the EPSRC, Industry and academia to highlight challenges in the area of Manufacturing.

Publications

Exploring the thermal behaviour of the solvated structures of Nifedipine
Jones Eleanor C L, Goldsmith Kate E, Ward Martin R, Bimbo Luis M, Oswald Iain D H
Acta Crystallographica Section B: Structural Science, Crystal Engineering and Materials Vol 79 (2023)
https://doi.org/10.1107/s2052520623001282
Crystal structure of a copper-mefenamate complex solvated with diglyme and water
Chong Magdalene W S, Ottoboni Sara, Martin Alan R G, Bowering Deborah, Price Chris J, Nordon Alison, Oswald Iain D H, Ward Martin R
Acta Crystallographica Section E: Structure Reports Vol 78 (2022)
https://doi.org/10.1107/S2056989022010647
Probing the effect of non-/hydrostatic pressures on ofloxacin and levofloxacin
Gasol Cardona Julia, Ward Martin R, Markl Daniel, Maloney Andrew GP, Oswald Iain D H
CMAC Annual Open Day 2022, pp. 39-39 (2022)
Recovery of high-pressure solid forms to ambient conditions
Ward Martin, Oswald Iain D H
CMAC Annual Open Day 2022, pp. 43-43 (2022)
Discovery and applications of a novel solid-state arrangement : water bridge salt form
Tanveer Saadia, Oswald Iain D H, Florence Alastair J
CMAC Annual Open Day 2022, pp. 34-34 (2022)
Pressure-induced superelastic behaviour of isonicotinamide
Jones Eleanor, Bebiano Suse S, Ward Martin R, Bimbo Luis M, Oswald Iain DH
Chemical Communications Vol 57, pp. 11827-11830 (2021)
https://doi.org/10.1039/D1CC04692F

More publications

Professional activities

Pharmaceuticals under high pressure
Recipient
10/9/2021
The Pharmacology of Harry Potter Potions
Speaker
16/8/2021
British Crystallographic Association Meeting (Event)
Chair
1/4/2021
European Science Foundation (Journal)
Peer reviewer
1/7/2020
Pressure on molecular systems: insights into new solid forms
Speaker
22/6/2020
Potions and Pharmacology: The science behind Harry Potters potions!
Contributor
6/2/2020

More professional activities

Projects

KTP - GlaxoSmithKline plc. Understanding the different polymorphs in APIs which impact stability and biopharmaceutics.
Markl, Daniel (Principal Investigator) Oswald, Iain (Co-investigator)
01-Jan-2022 - 31-Jan-2024
Doctoral Training Partnership 2020-2021 University of Strathclyde | Tanveer, Saadia
Florence, Alastair (Principal Investigator) Oswald, Iain (Co-investigator) Tanveer, Saadia (Research Co-investigator)
01-Jan-2022 - 01-Jan-2025
Doctoral Training Partnership 2020-2021 University of Strathclyde | Chambers, Greg
Perrie, Yvonne (Principal Investigator) Ter Horst, Joop (Principal Investigator) Oswald, Iain (Co-investigator) Chambers, Greg (Research Co-investigator)
01-Jan-2020 - 01-Jan-2024
Quantifying the Dynamic Response in Metal-Organic Frameworks (MOFs): A Platform for Tuning Chemical Space in Porous Materials
Fletcher, Ashleigh (Principal Investigator) Oswald, Iain (Co-investigator)
Quantifying the Dynamic Response in Metal-Organic Frameworks (MOFs): A Platform for Tuning Chemical Space in Porous Materials
01-Jan-2020 - 30-Jan-2023
From crystal to tablet – linking structure to function through compression studies
Oswald, Iain (Principal Investigator) Markl, Daniel (Co-investigator)
01-Jan-2020 - 30-Jan-2023
Investigation of maleic-d2 acid isomerization at high pressure
Ward, Martin (Principal Investigator) Oswald, Iain (Co-investigator)
We will use central facilities time (ISIS neutron and muon facility) to study the conversion of maleic to fumaric acid under high pressure and temperature conditions. Experiments performed in-house show that temperature of pressure alone do not significantly influence the conversion of maleic to fumaric acid; however, the combination of both does result in successful conversion. Neutron experiments will elucidate the conversion in-situ, as it progresses, and allow us to identify ciritcal conditions of temperature and pressure to cause this conversion.
26-Jan-2019

More projects

Address

Strathclyde Institute of Pharmacy and Biomedical Sciences
Robertson Wing

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