Dr Iain Oswald

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Strathclyde Institute of Pharmacy and Biomedical Sciences

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Personal statement

Iain D.H. Oswald graduated from the University of Edinburgh (2001) and remained there in the group of Professor Simon Parsons to study hydrogen-bonding patterns and co-crystallisation as part of his PhD. Fortunately, this research expanded to investigate the effects of high pressure which allowed him the opportunity to work at the European Synchrotron Radiation Facility in Grenoble. In 2004 he left for Grenoble where he became a postdoctoral researcher on the high pressure beamline (ID27). In 2006, he returned to Edinburgh to join the group of Colin R. Pulham and started a fellowship position funded by the Leverhulme Trust.

In 2009, Iain started his post at SIPBS as a Lecturer in Pharmaceutics and is interested and has been awarded funding in the areas of co-crystallisation of pharmaceutical materials at high pressure (EPSRC Early Career Fellowship, 2016-2021) and polymorphism and polymerisation of monomeric materials (Leverhulme Trust 2012-2015). 

Iain has contributed to the MPharm program as the 4th Year Co-ordinator (2012-2016) and has been an integral part of the redevelopment of the MPharm curriculum.  He was class coordinator for the 2nd year class Pharmaceutics (2013-2016) and for the Year 2 class Normal Function of the gastrointestinal tract (2012-2016).  Students in the 4th year of study will be able to work with Iain on research associated with pharmaceutical products in the solid state. His teaching activities extend to postgraduate degrees in the MRes Drug Delivery Systems and MSc Pharmaceutical Analysis course.

He was a member of the ESPRC Early Career Forum in Manufacturing from 2016-2020. The Forum is an excellent way to engage with others at a similar stage.  It seeks to engage with the EPSRC, Industry and academia to highlight challenges in the area of Manufacturing.

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Publications

Exploring the effects of high pressure on hydrogen bonding in pharmaceutical cocrystals : a systematic study of pyridine dicarboxylic acid systems using synchrotron and neutron diffraction
Ward Martin R, Bull Craig L, Funnell Nicolas P, Warren Mark R, Oswald Iain DH
International Journal of Pharmaceutics Vol 647 (2023)
https://doi.org/10.1016/j.ijpharm.2023.123514
Freeze-induced phase transition and local pressure in a phospholipid/water system : novel insights from a time/temperature resolved synchrotron X-ray diffraction study
Rodrigues Miguel A, Matsarskaia Olga, Rego Pedro, Geraldes Vitor, Connor Lauren E, Oswald Iain D H, Sztucki Michael, Shalaev Evgenyi
Molecular Pharmaceutics Vol 20, pp. 5790-5799 (2023)
https://doi.org/10.1021/acs.molpharmaceut.3c00657
Pushing technique boundaries to probe conformational polymorphism
Ward Martin R, Taylor Christopher R, Mulvee Matthew T, Lampronti Giulio I, Belenguer Ana M, Steed Jonathan W, Day Graeme M, Oswald Iain D H
Crystal Growth and Design Vol 23, pp. 7217-7230 (2023)
https://doi.org/10.1021/acs.cgd.3c00641
Dual-cell, high-pressure studies of porous, flexible frameworks from 20 to 30,000 bar
Ashworth David, Carrington Elliot J, McMonagle , Roseveare Thomas, Warren Mark, Fletcher Ashleigh, Moggach Stephen, Oswald Iain, Brammer Lee
IUCr 2023 - 26th Congress and General Assembly of the International Union of Crystallography (2023)
Pressure-induced postsynthetic cluster anion substitution in a MIL-53 topology scandium metal–organic framework
Thom Alexander J R, Turner Gemma F, Davis Zachary H, Ward Martin R, Pakamorė Ignas, Hobday Claire L, Allan David R, Warren Mark R, Leung Wai L W, Oswald Iain D H, Morris Russell E, Moggach Stephen A, Ashbrook Sharon E, Forgan Ross S
Chemical Science Vol 14, pp. 7716-7724 (2023)
https://doi.org/10.1039/D3SC00904A
Dual-cell, high-pressure studies of porous, flexible frameworks from 20 to 30,000 bar
Ashworth David, Carrington Elliot J, McMonagle Charles, Roseveare Thomas, Warren Mark, Fletcher Ashleigh, Moggach Stephen, Oswald Iain, Brammer Lee
6th Annual UK Porous Materials Conference (2023)

More publications

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Professional Activities

Application of calibration free approaches for rapid polymorph discrimination by Raman spectroscopy
Contributor
21/10/2024
Application of calibration free approaches for rapid polymorph discrimination by low frequency Raman spectroscopy
Contributor
25/4/2024
Pharmaceuticals under high pressure
Recipient
10/9/2021
The Pharmacology of Harry Potter Potions
Speaker
16/8/2021
British Crystallographic Association Meeting (Event)
Chair
1/4/2021
European Science Foundation (Journal)
Peer reviewer
1/7/2020

More professional activities

Projects

Industrial CASE Account - University of Strathclyde 2022 | Fetah, Banaz
Oswald, Iain (Principal Investigator) Markl, Daniel (Co-investigator) Fetah, Banaz (Research Co-investigator)
01-Oct-2022 - 01-Oct-2026
KTP - GlaxoSmithKline plc. Understanding the different polymorphs in APIs which impact stability and biopharmaceutics.
Markl, Daniel (Principal Investigator) Oswald, Iain (Co-investigator)
01-Sep-2022 - 31-Aug-2024
Doctoral Training Partnership 2020-2021 University of Strathclyde | Tanveer, Saadia
Florence, Alastair (Principal Investigator) Oswald, Iain (Co-investigator) Tanveer, Saadia (Research Co-investigator)
01-Jan-2022 - 01-Jul-2025
Doctoral Training Partnership 2020-2021 University of Strathclyde | Chambers, Greg
Perrie, Yvonne (Principal Investigator) Oswald, Iain (Co-investigator) Chambers, Greg (Research Co-investigator)
01-Nov-2020 - 01-Jan-2025
Investigation of pyrazine:diacid co-crystal systems at high pressure
Oswald, Iain (Principal Investigator) Ward, Martin (Co-investigator) Bull, Craig L. (Co-investigator) Funnell, Nicholas P. (Co-investigator)
The aim of this proposal is to follow the changes in the hydrogen bonding
interaction in the pyrazine:oxalic acid and the Pyrazine:maleic acid co-crystals to complete our combined synchrotron and neutron study of the pyrazine:diacid
system.
01-Oct-2020 - 06-Oct-2020
From crystal to tablet – linking structure to function through compression studies
Oswald, Iain (Principal Investigator) Markl, Daniel (Co-investigator)
01-Oct-2020 - 01-Oct-2024

More projects

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Contact

Dr Iain Oswald
Reader
Strathclyde Institute of Pharmacy and Biomedical Sciences

Email: iain.oswald@strath.ac.uk
Tel: 548 2157