Professor Yvonne Perrie

Head Of Institute

Strathclyde Institute of Pharmacy and Biomedical Sciences

Personal statement

My current position is Professor in Drug Delivery within the Strathclyde Institute of Pharmacy and Biomedical Sciences, University of Strathclyde, Glasgow, Scotland. In 1998 I gained my PhD from the University of London investigating the role of liposomes for DNA vaccines and drug delivery. I then worked within a newly established Drug Delivery Company (Lipoxen Technologies Ltd) for two years, developing their liposome drug delivery platform technology before moving into Academia to set up my own research group. I joined Aston University in 2000 and was appointed Professor in Drug Delivery in 2007. In 2016, I moved to the University of Strathclyde as Professor in Drug Delivery as part of the Global Talent Appointment Programme where I continue to develop and advance my research strategies.

My research is multi-disciplinary and focuses on developing drug delivery systems to facilitate the delivery of drugs and vaccines, thus providing practical solutions for current healthcare problems. I am an internationally recognised expert in the field of liposomes and particulate drug delivery research. My laboratory is fully equipped to manufacture and analyze a wide range of nanoparticles, including a suite of microfluidic systems that will provide the underpinning support for this project. I maintain a steady funding stream to support my research team through various sources, including Government Research Councils, European Framework Funding, Industrial Partners, and Charities.

My research and academic leadership has been recognised via a range of fellowships and awards including the Royal Pharmaceutical Society Harrison Memorial Medal (2019),  50th Anniversary Chair in Drug Delivery (2016), membership of the Controlled Release Society College of Fellows (2015), Fellow of the Royal Pharmaceutical Society (2014), Fellow of the Royal Society of Biology (2012), Eminent Fellow of the Academy of Pharmaceutical Sciences (2012), the Royal Pharmaceutical Society Pharmaceutical Scientist of the Year (2012), the British Science Festival Collaboration in Formulation Award (2011) and the Royal Pharmaceutical Society Science Conference Medal (2007).

Prizes and awards

Commissioner of the Commission on Human Medicines (CHM)
Recipient
1/5/2021
Chair of the Chemistry, Pharmacy and Standards Expert Advisory Group of the Commission on Human Medicines
Recipient
1/5/2021
Commission on Human Medicines COVID-19 Vaccines Benefit-Risk Expert Working Group
Recipient
1/11/2020
President of the Controlled Release Society (CRS)
Recipient
1/6/2020
COVID-19 Register of Experts for Scottish Government
Recipient
1/3/2020
Royal Pharmaceutical Society Harrison Medal
Recipient
31/7/2019

More prizes and awards

Publications

Non-canonical inflammasome activation mediates the adjuvanticity of nanoparticles
Muñoz-Wolf Natalia, Ward Ross W, Hearnden Claire H, Sharp Fiona A, Geoghegan Joan, O'Grady Katie, McEntee Craig P, Shanahan Katharine A, Guy Coralie, Bowie Andrew G, Campbell Matthew, Roces Carla B, Anderluzzi Giulia, Webb Cameron, Perrie Yvonne, Creagh Emma, Lavelle Ed C
Cell Reports Medicine Vol 4 (2023)
https://doi.org/10.1016/j.xcrm.2022.100899
Understanding protein corona formation under shear flow conditions
Daramy Karim, Perrie Yvonne, Rattray Zahra
JPAG Pharmaceutical Analysis Research Awards and Careers Fair 2022 (2022)
Exposure of the basophilic cell line KU812 to liposomes reveals activation profiles associated with potential anaphylactic responses linked to physico-chemical characteristics
Plant-Hately Alexander J, Eryilmaz Burcu, David Christopher A W, Brain Danielle E, Heaton Bethany J, Perrie Yvonne, Liptrott Neill J, Czajkowska-Kośnik Anna, Wróblewska Magdalena
Pharmaceutics Vol 14 (2022)
https://doi.org/10.3390/pharmaceutics14112470
Investigating the impact of shear flow on nanoparticle-protein interactions
Daramy Karim, Walker Joshua, Pei Yiwen, Minelli Caterina, Perrie Yvonne, Rattray Zahra
British Journal of Pharmacy Vol 7, pp. 51-52 (2022)
https://doi.org/10.5920/bjpharm.1131
Erratum : Mixing and flow-induced nanoprecipitation for morphology control of silk fibroin self-assembly
Matthew Saphia A L, Rezwan Refaya, Kaewchuchuen Jirada, Perrie Yvonne, Seib F Philipp
RSC Advances Vol 12, pp. 25006-25009 (2022)
https://doi.org/10.1039/D2RA90071H
Development of a rapid in vitro pre-screen for distinguishing effective liposome-adjuvant delivery systems
Feather Laura A J, Nadella Vinod, Kastner Elisabeth, Perrie Yvonne, Hilton Anthony C, Devitt Andrew
Scientific Reports Vol 12 (2022)
https://doi.org/10.1038/s41598-022-14449-7

More publications

Professional activities

Optimising the next generation of Lipid nanoparticles
Speaker
7/10/2022
Breaking Barriers
Organiser
20/9/2022
New Challenges for lipid nanoparticles
Speaker
11/7/2022
LNPs and Liposomes: formulation and manufacture
Speaker
12/6/2022
LNP Design and Manufacturing considerations
Speaker
26/5/2022
Lipid nanoparticles particles – what’s next?.
Speaker
11/5/2022

More professional activities

Projects

TargoPep: a cell selective delivery platform for therapeutic payloads (Follow on Fund)
Burley, Glenn (Principal Investigator) MacKay, Simon (Co-investigator) Perrie, Yvonne (Co-investigator) McWhinnie, Fergus (Research Co-investigator)
01-Jan-2023 - 31-Jan-2024
ICDDC - Interacellular Drug Delivery Centre
Perrie, Yvonne (Principal Investigator) Coxon, Geoffrey (Co-investigator)
01-Jan-2023 - 31-Jan-2026
NISV - Non Ionic Surfactant Vesicles
Roberts, Craig (Principal Investigator) Perrie, Yvonne (Co-investigator) Woods, Stuart (Research Co-investigator)
01-Jan-2022 - 27-Jan-2024
KTP - Target Healthcare Limited. Development of platform capability and creation of a robust framework for the assessment of shelf life and stability of a range of aseptically prepared Monoclonal Anti-Bodies (MABs) for patient use.
Perrie, Yvonne (Principal Investigator) Halbert, Gavin (Co-investigator)
24-Jan-2022 - 23-Jan-2024
Developing low temperature sensitive liposomes to deliver thrombolytics to venous thromboses, mediated by non-invasive high intensity focused ultrasound (HIFU)
Robertson, Craig (Principal Investigator) Perrie, Yvonne (Co-investigator)
03-Jan-2022 - 02-Jan-2023
Novel analytical pipelines for understanding oligonucleotide-loaded lipid nanoparticle critical quality attributes
Rattray, Zahra (Principal Investigator) Perrie, Yvonne (Co-investigator)
01-Jan-2022 - 31-Jan-2026

More projects

Address

Strathclyde Institute of Pharmacy and Biomedical Sciences
Robertson Wing

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