Personal statement
I am passionate about particles, especially how we can influence their formation by controlling crystallization to deliver particles with physical attributes designed to deliver optimal performance in formulated products. I have recently moved from managing particle science related innovation and product development in the pharmaceutical industry to pursue fundamental research in crystallization focussing on enhancing the purification of organic molecules by active intervention during the crystal growth process.
Professional activities
- Spatially Offset Raman Spectroscopy for the Monitoring of Solvent Content During Pharmaceutical Drying
- Contributor
- 12/4/2022
- CPACT Webinar Series
- Contributor
- 24/2/2022
- Development of Spatially Resolved Spectroscopy for In-line Monitoring of Pharmaceutical Drying
- Contributor
- 2022
- Spatially and Angularly Resolved Diffuse Reflectance NIR Spectroscopy for In-line Monitoring of Solvent Content During Pharmaceutical Drying
- Contributor
- 20/10/2021
- Integrated Filtration and Washing Modelling to Predict Continuous Isolation Performance.
- Contributor
- 2020
- Investigating the isolation performance of a novel continuous filtration unit for pharmaceutical process development and manufacturing: A case study using paracetamol and related impurities.
- Contributor
- 2019
More professional activities
Projects
- Sustainable Pharmaceutical Manufacturing: Computer aided solvent design to minimise solvent use across integrated synthesis, purification & isolation
- Price, Chris John (Principal Investigator) Kerr, William (Co-investigator) Li, Jun (Co-investigator) Lindsay, David (Co-investigator) Sefcik, Jan (Co-investigator)
- 11-Jan-2022 - 10-Jan-2025
- Visualization of fluid and impurity transport during filtration, washing and drying
- Ottoboni, Sara (Principal Investigator) Price, Chris John (Principal Investigator) Kathyola, Thokozile (Principal Investigator) Das, Gunjan (Principal Investigator) Schroeder, Sven L.M. (Principal Investigator)
- Isolating active pharmaceutical ingredients (APIs) of specified purity and particle size
distribution is an economically important industrial process. Problems with product
composition and performance can arise from uncontrolled processes that occur
during filtration, washing and drying. Physical transformations during these stages are
very poorly understood. We will use both in situ 2D imaging and ex situ 3D
tomography to elucidate the effects of API morphology, particle size/distribution, and
wash solvent miscibility and concentration. The results will inform best practice in
process design and operation to minimise out of specification product via mechanistic
understanding of the dissolution/precipitation/redistribution of impurities and
agglomeration. We hope to pinpoint microstructural variations in the porous bed and
the location of impurities and residual mother liquor inclusions. - 01-Jan-2021 - 31-Jan-2022
- Industrial Case Account - University of Strathclyde 2019 | Eales, William
- Price, Chris John (Principal Investigator) Mulheran, Paul (Co-investigator) Eales, William (Research Co-investigator)
- 01-Jan-2019 - 01-Jan-2023
- Industrial Case Account - University of Strathclyde 2019 / S190404-113
- Price, Chris John (Principal Investigator)
- 01-Jan-2019 - 30-Jan-2024
- Master Development Manufacturing Services Agreement CMAC National Facility NF179
- Florence, Alastair (Principal Investigator) Price, Chris John (Co-investigator)
- 01-Jan-2019 - 30-Jan-2019
- AZ compounds for evaluation in Continuous Filtration Device
- Price, Chris John (Principal Investigator)
- 05-Jan-2017 - 07-Jan-2018
More projects
Address
Chemical and Process Engineering
James Weir
James Weir
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