Professor Chris John Price

Chair In Industrial Crystallisation

Chemical and Process Engineering


Personal statement

I am passionate about particles, especially how we can influence their formation by controlling crystallization to deliver particles with physical attributes designed to deliver optimal performance in formulated products. I have recently moved from managing particle science related innovation and product development in the pharmaceutical industry to pursue fundamental research in crystallization focussing on enhancing the purification of organic molecules by active intervention during the crystal growth process.

Back to staff profile


Digital process design to define and deliver pharmaceutical particle attributes
Urwin Stephanie J, Chong Magdalene WS, Li Wei, McGinty John, Mehta Bhavik, Ottoboni Sara, Pathan Momina, Prasad Elke, Robertson Murray, McGowan Mark, al-Attili Mais, Gramadnikova Ekaterina, Siddique Mariam, Houson Ian, Feilden Helen, Benyahia Brahim, Brown Cameron J, Halbert Gavin W, Johnston Blair, Nordon Alison, Price Chris J, Reilly Chris D, Sefcik Jan, Florence Alastair J
Chemical Engineering Research and Design Vol 196, pp. 726-749 (2023)
Properties of packed bed structures formed during filtration : a two and three-dimensional model
Eales William, Price Chris J, Hicks William, Mulheran Paul A
Organic Process Research and Development (2023)
Development of a spatially offset Raman spectroscopy probe for monitoring pharmaceutical drying
Al-Attili Mais, Ferreira Carla, Price Chris, Faulds Karen, Chen Yi-Chieh
Chemical Engineering Research and Design Vol 192, pp. 510-520 (2023)
Modelling solution speciation to predict pH and supersaturation for design of batch and continuous organic salt crystallisation processes
McGinty John, Wheatcroft Helen, Price Chris J, Sefcik Jan
Fluid Phase Equilibria Vol 565 (2023)
Crystal structure of a copper-mefenamate complex solvated with diglyme and water
Chong Magdalene W S, Ottoboni Sara, Martin Alan R G, Bowering Deborah, Price Chris J, Nordon Alison, Oswald Iain D H, Ward Martin R
Acta Crystallographica Section E: Structure Reports Vol 78 (2022)
Digital design of filtration and washing of active pharmaceutical ingredients via mechanistic modelling
Ottoboni Sara, Brown Cameron J, Mehta Bhavik, Jimeno Guillermo, Mitchell Niall A, Sefcik Jan, Price Chris J
Organic Process Research and Development Vol 26, pp. 3236-3253 (2022)

More publications

Back to staff profile

Professional Activities

Development of a Spatially Resolved Spectroscopy probe for In-line Monitoring of Pharmaceutical Drying
Spatially Offset Raman Spectroscopy for the Monitoring of Solvent Content During Pharmaceutical Drying
CPACT Webinar Series
Development of Spatially Resolved Spectroscopy for In-line Monitoring of Pharmaceutical Drying
Spatially and Angularly Resolved Diffuse Reflectance NIR Spectroscopy for In-line Monitoring of Solvent Content During Pharmaceutical Drying
Integrated Filtration and Washing Modelling to Predict Continuous Isolation Performance.

More professional activities


Sustainable Pharmaceutical Manufacturing: Computer aided solvent design to minimise solvent use across integrated synthesis, purification & isolation
Price, Chris John (Principal Investigator) Kerr, William (Co-investigator) Li, Jun (Co-investigator) Lindsay, David (Co-investigator) Sefcik, Jan (Co-investigator)
11-Jan-2022 - 10-Jan-2025
Visualization of fluid and impurity transport during filtration, washing and drying
Ottoboni, Sara (Principal Investigator) Price, Chris John (Principal Investigator) Kathyola, Thokozile (Principal Investigator) Das, Gunjan (Principal Investigator) Schroeder, Sven L.M. (Principal Investigator)
Isolating active pharmaceutical ingredients (APIs) of specified purity and particle size
distribution is an economically important industrial process. Problems with product
composition and performance can arise from uncontrolled processes that occur
during filtration, washing and drying. Physical transformations during these stages are
very poorly understood. We will use both in situ 2D imaging and ex situ 3D
tomography to elucidate the effects of API morphology, particle size/distribution, and
wash solvent miscibility and concentration. The results will inform best practice in
process design and operation to minimise out of specification product via mechanistic
understanding of the dissolution/precipitation/redistribution of impurities and
agglomeration. We hope to pinpoint microstructural variations in the porous bed and
the location of impurities and residual mother liquor inclusions.
01-Jan-2021 - 31-Jan-2022
Industrial Case Account - University of Strathclyde 2019 / S190404-113
Price, Chris John (Principal Investigator)
01-Jan-2019 - 30-Jan-2024
Industrial Case Account - University of Strathclyde 2019 | Eales, William
Price, Chris John (Principal Investigator) Mulheran, Paul (Co-investigator) Eales, William (Research Co-investigator)
01-Jan-2019 - 01-Jan-2023
Master Development Manufacturing Services Agreement CMAC National Facility NF179
Florence, Alastair (Principal Investigator) Price, Chris John (Co-investigator)
01-Jan-2019 - 30-Jan-2019
AZ compounds for evaluation in Continuous Filtration Device
Price, Chris John (Principal Investigator)
05-Jan-2017 - 07-Jan-2018

More projects

Back to staff profile


Professor Chris John Price
Chair In Industrial Crystallisation
Chemical and Process Engineering

Tel: 574 5303