Professor Joop Ter Horst

Visiting Professor

Strathclyde Institute of Pharmacy and Biomedical Sciences

Personal statement

Joop ter Horst leads an application driven fundamental research group that will facilitate the paradigm shift to continuous manufacturing in the pharmaceutical industry. The group will identify routes to exploit the fundamental principles relating molecule, crystal structure and crystallization process phenomena to the crystal product quality to come to hybrid separation technologies to be incorporated in the continuous pharmaceutical manufacturing chain. He adopts a view from the molecular level and up for gaining fundamental understanding to use in control and prediction of new industrial crystallization processes. He cooperates with many university groups inside and outside the UK and his research benefits many industrial partners. 

Publications

Process modeling and optimization of continuous chiral resolution by integration of membrane and crystallization technologies
Capdevila-Echeverria Jose, Wang Jiayuan, Lakerveld Richard, ter Horst Joop H
Journal of Membrane Science Vol 632 (2021)
https://doi.org/10.1016/j.memsci.2021.119359
Extending the SAFT-γ Mie approach to model benzoic acid, diphenylamine, and mefenamic acid : solubility prediction and experimental measurement
Febra Sara A, Bernet Thomas, Mack Corin, McGinty John, Onyemelukwe Iyke I, Urwin Stephanie J, Sefcik Jan, ter Horst Joop H, Adjiman Claire S, Jackson George, Galindo Amparo
Fluid Phase Equilibria Vol 540 (2021)
https://doi.org/10.1016/j.fluid.2021.113002
Easy-to-use osmosis-based microfluidic chip for protein crystallization : application to a monoclonal antibody
Morais Sandy, Clisson Gérald, Mastropietro Teresa Fina, Briuglia Maria L, Ter Horst Joop H, Leng Jacques, Salmon Jean Baptiste
Crystal Growth and Design Vol 21, pp. 3469-3476 (2021)
https://doi.org/10.1021/acs.cgd.1c00248
Cocrystals of Praziquantel : discovery by network-based link prediction
Devogelaer Jan-Joris, Charpentier Maxime D, Tijink Arnoud, Dupray Valerie, Coquerel Gérard, Johnston Karen, Meekes Hugo, Tinnemans Paul, Vlieg Elias, ter Horst Joop H, de Gelder René
Crystal Growth and Design Vol 21, pp. 3428-3437 (2021)
https://doi.org/10.1021/acs.cgd.1c00211
Development of 3D printed rapid tooling for micro-injection moulding
Walsh Erin, ter Horst Joop H, Markl Daniel
Chemical Engineering Science Vol 235 (2021)
https://doi.org/10.1016/j.ces.2021.116498
Co-crystals of non-steroidal anti-inflammatory drugs (NSAIDs) : insight toward formation, methods, and drug enhancement
Nascimento André LCS, Fernandes Richard P, Charpentier Maxime D, ter Horst Joop H, Caires Flávio J, Chorilli Marlus
Particuology Vol 58, pp. 227-241 (2021)
https://doi.org/10.1016/j.partic.2021.03.015

More publications

Professional activities

Crystallization in Complex Multicomponent Systems
Speaker
5/6/2019
University of Rouen
Visiting researcher
3/6/2019
CORE Workshop
Participant
20/5/2019
Amecrys network meeting & review meeting
Participant
7/5/2019
External Examiner for the PhD student Marcelo Henriques da Silva in the group of Marcel Ottens at the TU Delft
Examiner
15/4/2019
Crystallization in Complex Multicomponent Systems
Speaker
11/4/2019

More professional activities

Projects

Doctoral Training Partnership 2020-2021 University of Strathclyde | Chambers, Greg
Perrie, Yvonne (Principal Investigator) Ter Horst, Joop (Principal Investigator) Oswald, Iain (Co-investigator) Chambers, Greg (Research Co-investigator)
01-Jan-2020 - 01-Jan-2024
to develop a workflow for the rapid measurement of phase diagrams for multicomponent systems student placement Olayinka Olalere
Ter Horst, Joop (Principal Investigator)
01-Jan-2018 - 31-Jan-2019
Doctoral Training Partnership (DTP 2016-2017 University of Strathclyde) | Walsh, Erin
Markl, Daniel (Principal Investigator) Ter Horst, Joop (Co-investigator) Walsh, Erin (Research Co-investigator)
01-Jan-2018 - 01-Jan-2022
CMAC Core project: Impurity Rejection
Florence, Alastair (Principal Investigator) Ter Horst, Joop (Co-investigator)
01-Jan-2017 - 30-Jan-2019
Future Continuous Manufacturing and Advanced Crystallisation Research Hub (CMAC Hub)
Florence, Alastair (Principal Investigator) Brown, Cameron (Co-investigator) Halbert, Gavin (Co-investigator) Johnston, Blair (Co-investigator) Markl, Daniel (Co-investigator) Nordon, Alison (Co-investigator) Price, Chris John (Co-investigator) Sefcik, Jan (Co-investigator) Ter Horst, Joop (Co-investigator)
01-Jan-2017 - 31-Jan-2023
Scale-Up and Continuos Viedma Ripening
Steendam, Rienk (Co-investigator) ter Keurst, Marc (Research Co-investigator) Ter Horst, Joop (Principal Investigator)
Viedma ripening involves the transformation of a racemic mixture of chiral crystals into one chiral form. Attempts were made to scale-up this process but failed. In this project the reason for the failed scale-up attempts will be investigated. Scale-up and continuous Viedma ripening will be attempted in a different manner using different setups, compounds and different crystal size distributions.
07-Jan-2016 - 12-Jan-2017

More projects

Address

Strathclyde Institute of Pharmacy and Biomedical Sciences

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