Dr Lian Tian

Senior Lecturer

Strathclyde Institute of Pharmacy and Biomedical Sciences

Contact

Personal statement

Lian obtained his PhD in Mechanical Engineering from the University of Colorado at Boulder in 2010. He then took his first postdoctoral training in Biomedical Engineering at the University of Wisconsin-Madison in USA and his second postdoctoral training in biology at Queen's University in Canada. He Joined SIPBS in 2020. As principal investigator of Cardiopulmonary Physiology, Biomechanics and Mechanobiology research group, his research focuses on cardiovascular physiology, biomechanics and mechanobiology, with a particular emphasis on pulmonary hypertension. The goal is to understand the mechanism at molecular, cellular, tissue and organ levels for disease diagnosis, monitoring and therapeutic treatment. His group has recently focused on right ventricular fibrosis and function in pulmonary hypertension.

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Publications

Dynamin 2 Regulates Mitochondrial Mitotic Fission in Pulmonary Hypertension
Dasgupta Asish, Chen Kuang-Hueih, Wu Danchen, Yerramilli V Siddartha, Lima Patricia D A, Martin Ashley Y, Bentley Rachel E T, Ott Benjamin P, Nandani Tanvi, Mewburn Jeffrey D, Tian Lian, Al-Qazazi Ruaa, Emon Isaac M, Colpman Pierce, Jefferson Lindsay, Noordhof Curtis, Jones Oliver, Hindmarch Charles C T, Archer Stephen L
Circulation research (2026)
https://doi.org/10.1161/CIRCRESAHA.125.327028
P15 Oestrogen and NFE2L2 signalling drive sex-specific mitochondrial responses in cardiac fibroblasts with implications for RV failure in PAH
Wilson Taryn, Tian Lian
2025 Autumn Meeting of the British Society for Cardiovascular Research, pp. A7.2-A7 (2025)
https://doi.org/10.1136/heartjnl-2025-bscr.17
Targeting mechanics to restore right ventricular function : a new frontier in pulmonary arterial hypertension therapy
Wilson Taryn, Tian Lian
Function Vol 6 (2025)
https://doi.org/10.1093/function/zqaf029
Sex differences in the right ventricle in the Sugen-Hypoxia rat model of pulmonary arterial hypertension
Coyle Chelbi, MacLean Margaret, Tian Lian
Circulation Vol 150, pp. A4137364 (2024)
https://doi.org/10.1161/circ.150.suppl_1.4137364
Influence of estrogen on right ventricular mitochondrial function in pulmonary hypertension
Coyle Chelbi, MacLean Margaret R, Tian Lian
Global Translational Medicine Vol 3 (2024)
https://doi.org/10.36922/gtm.2494
Sex-dependent mitochondrial function in right ventricle in an experimental model of pulmonary arterial hypertension
Tian Lian
British Society for Cardiovascular Research (BSCR) Autumn Meeting (2024)

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Research Interests

Cardiovascular physiology, biomechanics, mechanobiology and modeling in pulmonary hypertension

Professional Activities

NAMs Technology Partn3Ring webinar series: Session 3
Participant
20/5/2026
Comprehensive Physiology (Journal)
Peer reviewer
5/2026
EARA Webinar - Animal Research versus NAMs?
Participant
28/4/2026
Scottish Cardiovascular Forum
Participant
21/3/2026
Convenor for PhD viva
Examiner
13/1/2026
Mentoring at Strathclyde
Participant
1/12/2025

More professional activities

Projects

Modelling tricuspid valve dysfunction in pulmonary arterial hypertension through blood--tissue interaction analysis
Jia, Laibing (Principal Investigator) Tian, Lian (Co-investigator)
01-Jan-2026 - 31-Jan-2027
Fibroblast activation in the pressure loaded right ventricle
Tian, Lian (Principal Investigator)
15-Jan-2025 - 14-Jan-2026
Sex-dependent role of NFE2L2 in mitochondrial function in the right ventricle in pulmonary arterial hypertension
Tian, Lian (Principal Investigator)
01-Jan-2024 - 31-Jan-2026
Novel therapies targeting the right ventricle in pulmonary arterial hypertension
Tian, Lian (Principal Investigator)
01-Jan-2023 - 31-Jan-2026
Sex-dependent mitochondrial function in right ventricle in pulmonary arterial hypertension
Tian, Lian (Principal Investigator)
01-Jan-2021 - 31-Jan-2021
GEF ISP Lian Tan TU Graz Feb21
Tian, Lian (Principal Investigator)
24-Jan-2021 - 23-Jan-2022

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Contact

Dr Lian Tian
Senior Lecturer
Strathclyde Institute of Pharmacy and Biomedical Sciences

Email: lian.tian@strath.ac.uk
Tel: 0141 548 4968