Dr Lian Tian

Lecturer

Strathclyde Institute of Pharmacy and Biomedical Sciences

Personal statement

Lian obtained his PhD in Mechanical Engineering from the University of Colorado at Boulder in 2010. He then took his first postdoctoral training in Biomedical Engineering at the University of Wisconsin-Madison in USA and his second postdoctoral training in biology at Queen's University in Canada. He Joined SIPBS in 2020. His research interest is cardiovascular physiology, biomechanics and biology, particularly in pulmonary hypertension. His group has recently focused on right ventricular fibrosis and function in pulmonary hypertension.

Prizes and awards

Canadian Vascular Network trainee Travel Award for the Young Investigator Forum at Canadian Hypertension Congress: Recipient; 2019
Outstanding Oral Presentation at Canadian Hypertension Congress: Recipient; 2019
Queen’s University Post-Doctoral Travel Award: Recipient; 2018
ATS the Assembly on Pulmonary Circulation (PC) Abstract Scholarship: Recipient; 2018
Queen’s University Post-Doctoral Travel Award: Recipient; 2016
AHA 3CPR Junior Investigator Travel Stipend: Recipient; 2016

More prizes and awards

Publications

An integrated proteomic and transcriptomic signature of the failing right ventricle in monocrotaline induced pulmonary arterial hypertension in male rats: Hindmarch Charles Colin Thomas, Tian Lian, Xiong Ping Yu, Potus Francois, Bentley Rachel Emily Teresa, Al-Qazazi Ruaa, Prins Kurt W, Archer Stephen L; Frontiers in Physiology Vol 13 (2022); https://doi.org/10.3389/fphys.2022.966454
Macrophage-NLRP3 activation promotes right ventricle failure in pulmonary arterial hypertension: Al-Qazazi Ruaa, Lima Patricia DA, Prisco Sasha Z, Potus Francois, Dasgupta Asish, Chen Kuang-Hueih, Tian Lian, Bentley Rachel E T, Mewburn Jeff, Martin Ashley Y, Wu Danchen, Jones Oliver, Maurice Donald H, Bonnet Sebastien, Provencher Steeve, Prins Kurt W, Archer Stephen L; American Journal of Respiratory and Critical Care Medicine Vol 206, pp. 608-624 (2022); https://doi.org/10.1164/rccm.202110-2274OC
Inhibiting pyruvate kinase muscle isoform 2 regresses group 2 pulmonary hypertension induced by supra-coronary aortic banding: Xiong Ping Yu, Motamed Mehras, Chen Kuang-Hueih, Dasgupta Asish, Potus François, Tian Lian, Martin Ashley, Mewburn Jeffrey, Jones Oliver, Thébaud Arthur, Archer Stephen L; Acta Physiologica Vol 234 (2022); https://doi.org/10.1111/apha.13764
PINK1-induced phosphorylation of mitofusin 2 at serine 442 causes its proteasomal degradation and promotes cell proliferation in lung cancer and pulmonary arterial hypertension: Dasgupta Asish, Chen Kuang-Hueih, Lima Patricia DA, Mewburn Jeffrey, Wu Danchen, Al-Qazazi Ruaa, Jones Oliver, Tian Lian, Potus Francois, Bonnet Sebastien, Archer Stephen L; FASEB Journal Vol 35 (2021); https://doi.org/10.1096/fj.202100361R
Oxygen sensing, mitochondrial biology and experimental therapeutics for pulmonary hypertension and cancer: Wu Danchen, Dasgupta Asish, Read Austin D, Bentley Rachel ET, Motamed Mehras, Chen Kuang-Hueih, Al-Qazazi Ruaa, Mewburn Jeffrey D, Dunham-Snary Kimberly J, Alizadeh Elahe, Tian Lian, Archer Stephen L; Free Radical Biology and Medicine Vol 170, pp. 150-178 (2021); https://doi.org/10.1016/j.freeradbiomed.2020.12.452
Excess protein O-GlcNAcylation links metabolic derangements to right ventricular dysfunction in pulmonary arterial hypertension: Prisco Sasha Z, Rose Lauren, Potus Francois, Tian Lian, Wu Danchen, Hartweck Lynn, Al-Qazazi Ruaa, Neuber-Hess Monica, Eklund Megan, Hsu Steven, Thenappan Thenappan, Archer Stephen L, Prins Kurt W; International Journal of Molecular Sciences Vol 21 (2020); https://doi.org/10.3390/ijms21197278

More publications

Research interests

Cardiovascular physiology, biomechanics, biology and modeling in pulmonary hypertension

Professional activities

RSE EDI Focus group: Participant; 26/1/2023
SIPBS 3Rs Event: Participant; 8/12/2022
Scottish Right Heart Symposium: Participant; 8/11/2022
Faculty of Science Chancellor’s Fellow and Early Career Event: Participant; 29/6/2022
RSE Network Event: Participant; 6/4/2022
Respiratory Research (Journal): Peer reviewer; 4/2022

More professional activities

Projects

Sex-dependent mitochondrial function in right ventricle in pulmonary arterial hypertension: Tian, Lian (Principal Investigator); 01-Jan-2021 - 31-Jan-2021
GEF ISP Lian Tan TU Graz Feb21: Tian, Lian (Principal Investigator); 24-Jan-2021 - 23-Jan-2022
Doctoral Training Partnership 2020-2021 University of Strathclyde | Coyle, Chelbi: Tian, Lian (Principal Investigator) MacLean, Mandy (Co-investigator) Coyle, Chelbi (Research Co-investigator); 01-Jan-2020 - 01-Jan-2024

Address

Strathclyde Institute of Pharmacy and Biomedical Sciences
Robertson Wing

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