Testing and Improvement of Drug formulations

This project aims to improve delivery and targeting of existing drugs available to treat diseases such as diabetes, hypertension and cardiovascular disease (CVD).

There is a need for further research to develop formulations that can be administered orally rather than intravenously, use lower drug doses, have improved safety and therapeutic profiles. We intend to show the benefits of advanced delivery systems (nanoparticles) against the conventional formulations.

The project has several short-term, moderate and long-term benefits for healthcare.

Short-term

The short term benefits are understanding how drugs are distributed and the how easy it would be to introduce novel delivery strategies in a preclinical setting.

Moderate

The moderate benefits include identifying the new indications of existing drugs aided by better delivery approaches

Long term

The long term benefits include the better management of human healthcare thereby cost-cutting to the NHS where there is significant spend in diabetes and CVD.