Publications

Establishing the scalability of micro/milli-scale antibody-drug conjugate conjugation reactions

Armstrong Georgina

16th PharmSci International Conference (2025)

Antibody-drug conjugates as multimodal therapies against hard-to-treat cancers

Armstrong Georgina B, Graham Harriet, Cheung Anthony, Montaseri Hanieh, Burley Glenn A, Karagiannis Sophia N, Rattray Zahra

Advanced Drug Delivery Reviews Vol 224 (2025)

https://doi.org/10.1016/j.addr.2025.115648

Assessment of biophysical properties of the first-in-class anti-cancer IgE antibody drug, MOv18 IgE demonstrates monomeric purity and stability

Considine Paul, Punnabhum Panida, Davidson Callum G, Armstrong Georgina B, Kreiner Michaela, Bax Heather J, Chauhan Jitesh, Spicer James, Josephs Debra H, Karagiannis Sophia N, Halbert Gavin, Rattray Zahra

mAbs Vol 17 (2025)

https://doi.org/10.1080/19420862.2025.2512211

Reconciling predicted and measured viscosity parameters in high concentration therapeutic antibody solutions

Armstrong Georgina Bethany, Roche Aisling, Lewis William, Rattray Zahra

mAbs Vol 16 (2024)

https://doi.org/10.1080/19420862.2024.2438172

Assessing the manufacturability and critical quality attribute profiles of anti-IL-8 immunoglobulin G mutant variants

Armstrong Georgina Bethany, Burley Glenn A, Lewis William, Rattray Zahra

Molecular Pharmaceutics Vol 21, pp. 6423–6432 (2024)

https://doi.org/10.1021/acs.molpharmaceut.4c01010

A framework for the biophysical screening of antibody mutations targeting solvent-accessible hydrophobic and electrostatic patches for enhanced viscosity profiles

Armstrong Georgina B, Shah Vidhi, Sanches Paula, Patel Mitul, Casey Ricky, Jamieson Craig, Burley Glenn A, Lewis William, Rattray Zahra

Computational and Structural Biotechnology Journal Vol 23, pp. 2345-2357 (2024)

https://doi.org/10.1016/j.csbj.2024.05.041

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Professional Activities

The developability of monoclonal antibody based therapies

Contributor

15/5/2025

Sequence engineering to improve syringeability of high concentration mAb formulations

Speaker

23/11/2022

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Projects

Sequence engineering to improve the performance of biopharma in patient administration syringe devices

Rattray, Zahra (Principal Investigator) Jamieson, Craig (Principal Investigator) Armstrong, Georgina (Post Grad Student)

01-Jan-2021 - 30-Jan-2024

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