Dr Hilary Carswell

Senior Lecturer

Strathclyde Institute of Pharmacy and Biomedical Sciences

Personal statement

I am a Senior Research Lecturer in in vivo Biology with particular interests in brain damage and repair. I registered as a Pharmacist in 1992 and obtained my PhD in 1996 at University of Glasgow during which I developed a deep interest in brain damage. I pursued my academic career in stroke research as a postdoctoral researcher and latterly a research fellow at the Wellcome Surgical Institute, University of Glasgow before joining SIPBS in 2007.

My research focuses on understanding mechanisms of brain damage and repair using two strategies namely inflammation and stem cells. I have particular interest in in vivo models of brain damage and current research programmes include understanding how to promote success of stem cells in vivo and the roles of inflammatory cells such as mast cells in stroke. We maintain strong national and international collaborative links with stroke clinicians and researchers, immunologists and Biotech and Pharmaceutical Industry.  

I aim to generate student engagement and research aspirations in Pharmacy and Biomedical Science students and to promote opportunities in science in interdisciplinary areas. 

Publications

In vitro studies on space-conforming self-assembling silk hydrogels as a mesenchymal stem cell-support matrix suitable for minimally invasive brain application
Osama I, Gorenkova N, McKittrick CM, Wongpinyochit T, Goudie A, Seib FP, Carswell HVO
Scientific Reports Vol 8 (2018)
https://doi.org/10.1038/s41598-018-31905-5
Detrimental effects of 2-arachidonoylglycerol on whole blood platelet aggregation and on cerebral blood flow after a focal ischemic insult in rats
Shearer Jennifer A, Coker Susan J, Carswell Hilary V O
American Journal of Physiology - Heart and Circulatory Physiology Vol 314, pp. 967-977 (2018)
https://doi.org/10.1152/ajpheart.00299.2017
Placenta-derived cells for acute brain injury
Pischiutta Francesca , Sammali Eliana , Parolini Ornella , Carswell Hilary V O, Zanier Elisa R
Cell Transplantation Vol 27, pp. 151-167 (2018)
https://doi.org/10.1177/0963689717732992
In vivo evaluation of engineered self-assembling silk fibroin hydrogels after intracerebral injection in a rat stroke model
Gorenkova Natalia, Osama Ibrahim, Seib F Philipp, Carswell Hilary
ACS Biomaterials Science & Engineering (2018)
https://doi.org/10.1021/acsbiomaterials.8b01024
The IMPROVE guidelines (ischaemia models: procedural refinements of in vivo experiments)
Percie du Sert Nathalie, Alfieri Alessio, Allan Stuart M, Carswell Hilary VO, Deuchar Graeme A, Farr Tracy D , Flecknell Paul, Gallagher Lindsay, Gibson Claire L, Haley Michael J , Macleod Malcolm R , McColl Barry W , McCabe Christopher , Morancho Anna , Moon Lawrence DF, O’Neill Michael J , Pérez de Puig Isabel , Planas Anna , Ragan C Ian , Rosell Anna , Roy Lisa A , Ryder Kathryn O , Simats Alba , Sena Emily S , Sutherland Brad A , Tricklebank Mark D , Trueman Rebecca C , Whitfield Lucy , Wong Raymond , Macrae I Mhairi
Journal of Cerebral Blood Flow and Metabolism, pp. 1-30 (2017)
https://doi.org/10.1177/0271678X17709185
An in vitro microfluidic model of microglia migration after stroke
White S, Plevin R, Zagnoni M, Carswell H
Journal of Cerebral Blood Flow and Metabolism Vol 37 (2017)
https://doi.org/10.1177/0271678X17695986

more publications

Professional activities

28th Symposium on Cerebral Blood Flow, Metabolism and Function
Participant
1/3/2017

more professional activities

Projects

Pharmacells contribution to IAA Secondment
Carswell, Hilary (Principal Investigator) Pickard, Ben (Co-investigator)
25-Jan-2016 - 31-Jan-2017
Development of starting materials for cell-based treatments (project plan for SMART grant)
Carswell, Hilary (Principal Investigator) Carter, Katharine (Co-investigator) Currie, Susan (Co-investigator) Pickard, Ben (Co-investigator) Williams, Roderick (Co-investigator)
01-Jan-2015 - 31-Jan-2016
BBSRC Doctoral Training Grant (DTG) | White, Samantha
Carswell, Hilary (Principal Investigator) Plevin, Robin (Co-investigator) White, Samantha (Research Co-investigator)
01-Jan-2013 - 20-Jan-2018
BB/J013854/1 BBSRC DPT Studentships (with Glasgow University) | White, Samantha
Carswell, Hilary (Principal Investigator) Plevin, Robin (Co-investigator) White, Samantha (Research Co-investigator)
01-Jan-2013 - 20-Jan-2018
Modulating the autophagy cellular stress response pathway in neural stem cells
Chan, Edmond (Principal Investigator) Carswell, Hilary (Co-investigator)
01-Jan-2013 - 31-Jan-2014
Impact Acceleration Account - University Of Strathclyde 2012 / R120526-231
Carswell, Hilary (Principal Investigator)
01-Jan-2012 - 31-Jan-2017

more projects

Address

Strathclyde Institute of Pharmacy and Biomedical Sciences
Hamnett Wing

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