Dr Hilary Carswell

Reader

Strathclyde Institute of Pharmacy and Biomedical Sciences

Contact

Personal statement

I am a Reader at University of Strathclyde with particular interests in brain damage and repair. After registering as a Pharmacist then obtaining my PhD at University of Glasgow, I pursued my academic career in preclinical stroke research as a postdoctoral researcher. I acquired an independant research fellowship from Research into Agening at the Wellcome Surgical Institute, University of Glasgow before joining SIPBS in 2007, where I am joined as a John Anderson Research Lecturer in in vivo Biology. 

My research focuses on understanding mechanisms of brain damage and repair using two strategies namely inflammation and stem cells. I have particular interest in in vivo and in vitro models of brain damage and current research programmes include understanding how to promote success of stem cells for brain repair as well as targetting inflammation and the blood brain barrier in stroke. We maintain strong national and international collaborative links with stroke clinicians and researchers, immunologists and Biotech and Pharmaceutical Industry. My research group currently has 3 PhD students and 1 PDRA, funded an International Collaborative Grant from Saudi Arabia and by Joint Tenovus Scotland & Neurosciences Foundation and Thai Government.  

I aim to generate student engagement and research aspirations in Pharmacy and Biomedical Science students and to promote opportunities in science in interdisciplinary areas. In 2018 I was Winner of Best Teacher in Faculty of Science Strathclyde Teaching Excellence Awards, which is evidence of success of my innovative teaching approaches. An example of a student’s quote ‘Her thoroughness, combined with her approachability, enthusiasm and expertise mark Hilary out as an exceptional teacher, who is devoted to her students’.

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Publications

The therapeutic potential of drug-like small molecule analogues of the parasitic worm product ES-62 in cerebral small vessel disease
Lumbreras Perales Cristina, Harnett William, Suckling Colin, Scott Fraser, Van Agtmael Tom, Carswell Hilary
6th UK Preclinical Stroke Symposium 2023 (2023)
Do parasitic worm products reverse endothelial dysfunction in cerebral small vessel disease?
Lumbreras Perales Cristina, Suckling Colin, Scott Fraser, Harnett William, Van Agtmael Tom, Carswell Hilary
6th UK Preclinical Stroke Symposium 2023 (2023)
Can worm-based products reduce inflammatory burden in cerebral small vessel disease?
Lumbreras Perales Cristina, Harnett William, Suckling Colin, Scott Fraser, Van Agtmael Tom, Carswell Hilary
6th UK Preclinical Stroke Symposium 2023 (2023)
Development of an in vitro model of spatiotemporal oxygen-glucose deprivation for the study of microglial migration after stroke
Aruvornlop Panicha, Zagnoni Michele, Carswell Hilary
6th UK Preclinical Stroke Symposium 2023 (2023)
Targeting 17β-estradiol biosynthesis in neural stem cells improves stroke outcome
Patkar Shalmali, Uwanogho Dafe, Modo Michel, Tate Rothwelle J, Plevin Robin, Carswell Hilary V O
Frontiers in Cellular Neuroscience Vol 16 (2022)
https://doi.org/10.3389/fncel.2022.917181
Modelling microglial migration in stroke with microfluidic technology
Aruvornlop P, Zagnoni M, Carswell H
Journal of Cerebral Blood Flow and Metabolism Vol 42, pp. 159 (2022)
https://doi.org/10.1177/0271678X221096357

More publications

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Professional Activities

PhD student selected for oral presentation at international conference due to outstanding abstract.
Contributor
5/9/2023
6th UK Preclinical Stroke Symposium
Participant
4/9/2023
6th UK Preclinical Stroke Symposium in September 2023
Organiser
4/9/2023
Tom Van Agtmael
Host
21/4/2023
Invited external examiner for MPharm degree at University of Newcastle
External Examiner
1/3/2023
Invited External examiner for PhD viva at U of Manchester
External Examiner
23/2/2023

More professional activities

Projects

Establishing cerebral organoids as a human model of stroke
Carswell, Hilary (Principal Investigator) Bushell, Trevor (Co-investigator) McMullen, Calum (Co-investigator) Seib, Philipp (Co-investigator)
04-Jan-2023 - 03-Jan-2025
Biocompatible silk hydrogels as tunable stem cell constructs for the treatment of stroke. (skype)
Carswell, Hilary (Principal Investigator) Seib, Philipp (Co-investigator) Khadra, Ibrahim (Research Co-investigator)
01-Jan-2020 - 30-Jan-2023
Efficacy of small molecule analogues of the anti-inflammatory parasitic worm product, ES-62, in protecting against stroke
Carswell, Hilary (Principal Investigator) Harnett, William (Co-investigator)
01-Jan-2020 - 31-Jan-2025
Pharmacells contribution to IAA Secondment
Carswell, Hilary (Principal Investigator) Pickard, Ben (Co-investigator) McKittrick, Craig (Research Co-investigator)
25-Jan-2016 - 31-Jan-2017
Silk biomaterials for the stroked brain
Carswell, Hilary (Co-investigator) Seib, Philipp (Co-investigator) Gorenkova, Natalia (Fellow)
12-Jan-2015 - 11-Jan-2017
Development of starting materials for cell-based treatments (project plan for SMART grant)
Carswell, Hilary (Principal Investigator) Carter, Katharine (Co-investigator) Currie, Susan (Co-investigator) Pickard, Ben (Co-investigator) Williams, Roderick (Co-investigator) McKittrick, Craig (Researcher)
01-Jan-2015 - 31-Jan-2016

More projects

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Contact

Dr Hilary Carswell
Reader
Strathclyde Institute of Pharmacy and Biomedical Sciences

Email: hilary.carswell@strath.ac.uk
Tel: 548 4956