Dr Susan Chalmers

Senior Lecturer

Strathclyde Institute of Pharmacy and Biomedical Sciences

Personal statement

I am a Chancellors Research Fellow, examining the role of mitochondria in the normal function of cells of the brain (neurons, glia and cerebrovasculature), as well as the role that mitochondria play in protecting or contributing to neurodegeneration or dysfunction in disease. Current particular areas of focus include alterations in mitochondrial motility and functionality due to amyloid-β or hyperglycaemia.


Find out more about neuroscience research at Strathclyde and view our MSc Neuroscience & Mental Health programme.



Has expertise in:

    I am the University representative for The Physiological Society (https://www.physoc.org/) - please do contact me with any queries relating to membership, grant applications, conferences or any other aspect of support that the Society offers.

    Core lab techniques and capabilities include:

    • primary neuronal / glial / smooth muscle cell isolation and culture
    • live-cell fluorescence imaging (Ca2+, organelle transport, ROS etc)
    • image analysis & quantification


Fellow of the Higher Education Academy

PhD (Dundee / Buck Institute for Age Research, CA)

BSc (Hons) (Aberdeen)


Sunitinib and imatinib display differential cardiotoxicity in adult rat cardiac fibroblasts that involves a role for calcium/calmodulin dependent protein kinase II
McMullen Calum J, Chalmers Susan, Wood Rachel, Cunningham Margaret R, Currie Susan
Frontiers in Cardiovascular Medicine Vol 7 (2021)
MSc Neuroscience & Mental Health
Chalmers Susan
FENS Forum of Neuroscience 2020 (2020)
Oscillating glucose impairs anterograde motility of mitochondria in neuron
Greenwood Eleanor, Chalmers Susan
FENS Forum of Neuroscience 2020 (2020)
Sunitinib mediates mitochondrial ROS production in adult rat cardiac fibroblasts via CaMKII oxidation
McMullen CJ, Chalmers S, Cunningham MR, Currie S
Heart Vol 106 (2020)
MYC regulates fatty acid metabolism through a multigenic program in claudin-low triple negative breast cancer
Casciano Jessica C, Perry Caroline, Cohen-Nowak Adam J, Miller Katelyn D, Voorde Johan Vande, Zhang Qifeng, Chalmers Susan, Sandison Mairi E, Lui Qin, Hedley Ann, McBryan Tony, Tang Hsin-Yao, Gorman Nicole, Beer Thomas, Speicher David W, Adams Peter D, Lui Xuefeng, Schlegel Richard, McCarron John G, Wakelam Michael J O, Gottlieb Eyal, Kossenkov Andrew V, Schug Zachary T
British Journal of Cancer Vol 122, pp. 868-884 (2020)
Multi-omics studies demonstrate Toxoplasma gondii-induced metabolic reprogramming of murine dendritic cells
Hargrave Kerrie E, Woods Stuart, Millington Owain, Chalmers Susan, Westrop Gareth D, Roberts Craig W
Frontiers in Cellular and Infection Microbiology : Parasite and Host Vol 9 (2019)

More publications


I teach on both the Biomedical Sciences and MPharm degree programs and am course coordinator for the in MSc Neuroscience & Mental Health, as well as module coordinator for year 3 MPharm Management of Cardiovascular Conditions. I host Masters students in the lab - MSc, MSci and MRes projects, in addition to supervising/co-supervising 2 PhD students and 2 EngD students.


Find out more about neuroscience research at Strathclyde and view our MSc Neuroscience & Mental Health programme.


Research interests

My primary research interest is in mitochondria, with a particular focus on the involvement of these small organelles with calcium signalling processes and the changes associated with age and diseases. I use high-speed and timelapse fluorescence imaging to visualise and modulate mitochondria and calcium signals within live cells and tissue. 

Professional activities

Using storytelling to recount the untold narratives of breast cancer ​
Recounting the Untold Stories of Breast Cancer: Narratives from the Patient, Clinician and Scientist Perspective
Automated tracking of mitochondrial motility using image processing and epifluorescence microscopy
Career Carousel: opting for a career in science
Explorathon 2019 European Researchers Outreach Event
Day of Science @ Strathclyde - SIPBS: Cat Allergy Simulation and STEM activity stands

More professional activities


Recounting the Untold Stories of Breast Cancer: Narratives from the Patient, Clinician and Scientist Perspective
Rattray, Zahra (Principal Investigator) Rattray, Nicholas (Co-investigator) Cunningham, Margaret Rose (Co-investigator) Chalmers, Susan (Co-investigator) MCFADDEN, Yvonne (Co-investigator)
£5700 awarded to develop a series of storytelling events
14-Jan-2022 - 13-Jan-2023
Development of novel, automated analyses for the quantification of cellular and sub-cellular dynamics from fluorescence video-microscopy
Chalmers, Susan (Principal Investigator) Sandison, Mairi (Co-investigator) Murray, Paul (Co-investigator) Campbell, Andrew John (Co-investigator)
01-Jan-2020 - 11-Jan-2021
Mitochondrial amplification of local calcium entry and vascular contraction in hypertension
McCarron, John (Principal Investigator) Buckley, Charlotte (Co-investigator) Chalmers, Susan (Co-investigator) Wilson, Calum (Co-investigator)
Mitochondrial control of voltage-dependent calcium entry in hypertension
03-Jan-2020 - 08-Jan-2024
Home Office Project Licence P73667397
Chalmers, Susan (Principal Investigator)
Examining the role of mitochondria in neurodegeneration and vascular disorders
11-Jan-2019 - 11-Jan-2024
EPSRC Centre for Doctoral Training in Medical Devices and Health Technologies | Lachendro, Flynn James
Coupaud, Sylvie (Principal Investigator) Reid, Stuart (Principal Investigator) Chalmers, Susan (Co-investigator) Lachendro, Flynn James (Research Co-investigator)
01-Jan-2017 - 22-Jan-2022
Doctoral Training Partnership (DTP 2016-2017 University of Strathclyde) | Kim, So Jeong
Chalmers, Susan (Principal Investigator) Sandison, Mairi (Co-investigator) Kim, So Jeong (Research Co-investigator)
01-Jan-2016 - 01-Jan-2020

More projects


Strathclyde Institute of Pharmacy and Biomedical Sciences
Robertson Wing

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