Dr Peter Childs

Strathclyde Chancellor's Fellow

Biomedical Engineering

Personal statement

I am a Chancellors Fellow within the Department of Biomedical Engineering. My research interests include the control of cell function/fate through applied mechanical stimulation and development of materials for tissue regeneration (cellular and acellular). Since 2012 I have been involved with a multidisciplinary collaboration using nano amplitude vibration to stimulate stem cell osteogenesis ('nanokicking'). This technology is now being translated towards clinic as an osteogenic cell therapy for orthopaedic repair. I have also been involved in the translation of implantable bioactive polymers for growth factor delivery ('HealiOst'). Previously I was awarded a Royal Society of Edinburgh Enterprise Fellowship and have a keen interest in the clinical/commercial translation of cell engineering technologies.

Publications

Tissue engineered mimetic periosteum for efficient delivery of rhBMP-2
Romero-Torrecilla Juan Antonio, Muinos-Lopez Emma, Valdés-Fernández José, López-Martínez Tania, Ripalda-Cemboráin Purificación, Jayawarna Vineetha, Childs Peter, Salmeron-Sanchez Manuel, Prósper Felipe, Granero-Moltó Froilán
49th European Calcified Tissue Society Congress (2022)
https://doi.org/10.1016/j.bonr.2022.101252
Changes of nuclear and cellular properties following nanovibration of 3T3 fibroblastic cells
Johnson-Love Olivia, Campsie Paul, Reid Stuart, Espinosa Francisco, Garcia Ricardo, Dalby Matthew, Childs Peter
Future Investigators of Regenerative Medicine (2022)
Materials-driven fibronectin assembly on nanoscale topography enhances mesenchymal stem cell adhesion, protecting cells from bacterial virulence factors and preventing biofilm formation
Damiati Laila A, Tsimbouri Monica P, Hernandez Virginia-Llopis, Jayawarna Vineetha, Ginty Mark, Childs Peter, Xiao Yinbo, Burgess Karl, Wells Julia, Sprott Mark R, Meek R M Dominic, Li Peifeng, Oreffo Richard O C, Nobbs Angela, Ramage Gordon, Su Bo, Salmeron-Sanchez Manuel, Dalby Matthew J
Biomaterials Vol 280 (2022)
https://doi.org/10.1016/j.biomaterials.2021.121263
Nanovibrational stimulation inhibits osteoclastogenesis and enhances osteogenesis in co-cultures
Kennedy John W, Tsimbouri Monica P, Campsie Paul, Sood Shatakshi, Childs Peter G, Reid Stuart, Young Peter S, Meek Dominic R M, Goodyear Carl S, Dalby Matthew J
Scientific Reports Vol 11 (2021)
https://doi.org/10.1038/s41598-021-02139-9
The use of nanovibration to discover specific and potent bioactive metabolites that stimulate osteogenic differentiation in mesenchymal stem cells
Hodgkinson Thomas, Monica Tsimbouri P, Llopis-Hernandez Virginia, Campsie Paul, Scurr David, Childs Peter G, Phillips David, Donnelly Sam, Wells Julia, Salmerón-Sánchez Manuel, Burgess Karl E V, Alexander Morgan, Vassalli Massimo, Oreffo Richard, Reid Stuart, France David J, Dalby Matthew J
Science Advances Vol 7 (2021)
https://doi.org/10.1126/sciadv.abb7921
Tissue engineered scaffolds for mimetic autografts
Romero-Torrecilla Juan Antonio, Riera Luis, Valdés-Fernández José, López-Martínez Tania, Ripalda-Cemboráin Purificación, Jayawarna Vineetha, Childs Peter, Salmeron-Sanchez Manuel, Prósper-Cardoso Felipe, Granero-Moltó Froilán
ECTS 2020, pp. 11 (2020)
https://doi.org/10.1016/j.bonr.2020.100386

More publications

Professional activities

PhD examination
Examiner
29/7/2022
Cellular Mechanotransduction: Using vibration to manufacture a cellular ATMP
Speaker
15/3/2022
SULSA Our Future Health Innovation Fund Workshop
Participant
25/2/2022
Biomedical Engineering (Organisational unit)
Advisor
7/12/2021
Preclinical translation of mesenchymal stem cell therapies
Speaker
10/2021
MRes examination
Examiner
1/9/2021

More professional activities

Projects

BRAINS Strathclyde Centre for Doctoral Training
MacKenzie, Lewis (Principal Investigator) Childs, Peter (Principal Investigator) Witte, Kimia (Principal Investigator) Jimenez, Melanie (Principal Investigator) Chow, Shiao (Principal Investigator) Fu, Ying (Principal Investigator) Gomez-Roman, Natividad (Principal Investigator) Fazio, Mariana (Principal Investigator) Reid, Andrew Baxter (Principal Investigator)
Centre for Doctoral Training in Bridging Research and Advancements in Neurological Sciences (BRAINS). First cohort of PhD students starting autumn 2023.
01-Jan-2023
DTP 2224 University of Strathclyde | Pereira Sousa, Rui Pedro
Childs, Peter (Principal Investigator) Jimenez, Melanie (Co-investigator) Pereira Sousa, Rui Pedro (Research Co-investigator)
01-Jan-2022 - 01-Jan-2026
EPSRC REA - Mechanosensitivity of osteoporotic stem cells for diagnosis and treatment of osteoporosis
Childs, Peter (Principal Investigator) Jimenez, Melanie (Co-investigator)
01-Jan-2022 - 31-Jan-2026
Development of a new model of human vascular calcification
Wu, Junxi (Principal Investigator) Childs, Peter (Co-investigator)
15-Jan-2022 - 15-Jan-2022
Mechanobiology-based medicine
Childs, Peter (Principal Investigator)
01-Jan-2021 - 31-Jan-2022
Selective stem cell engineering through tuned mechanical loads
Childs, Peter (Principal Investigator)
31-Jan-2021 - 30-Jan-2022

More projects