Dr Peter Childs

Strathclyde Chancellor's Fellow

Biomedical Engineering

Personal statement

I am a Chancellors Fellow within the Department of Biomedical Engineering. My research interests include the control of cell function/fate through applied mechanical stimulation and development of materials for tissue regeneration (cellular and acellular). Since 2012 I have been involved with a multidisciplinary collaboration using nano amplitude vibration to stimulate stem cell osteogenesis ('nanokicking'). This technology is now being translated towards clinic as an osteogenic cell therapy for orthopaedic repair. I have also been involved in the translation of implantable bioactive polymers for growth factor delivery ('HealiOst'). Previously I was awarded a Royal Society of Edinburgh Enterprise Fellowship and have a keen interest in the clinical/commercial translation of cell engineering technologies.

Publications

The use of nanovibration to discover specific and potent bioactive metabolites that stimulate osteogenic differentiation in mesenchymal stem cells: Hodgkinson Thomas, Monica Tsimbouri P, Llopis-Hernandez Virginia, Campsie Paul, Scurr David, Childs Peter G, Phillips David, Donnelly Sam, Wells Julia, Salmerón-Sánchez Manuel, Burgess Karl E V, Alexander Morgan, Vassalli Massimo, Oreffo Richard, Reid Stuart, France David J, Dalby Matthew J; Science Advances Vol 7 (2021); https://doi.org/10.1126/sciadv.abb7921
Hurdles to uptake of mesenchymal stem cells and their progenitors in therapeutic products: Childs Peter G, Reid Stuart, Salmeron-Sanchez Manuel, Dalby Matthew J; The Biochemical journal Vol 477, pp. 3349-3366 (2020); https://doi.org/10.1042/BCJ20190382
Plasma polymerised nanoscale coatings of controlled thickness for efficient solid-phase presentation of growth factors: Alba-Perez Andres, Jayawarna Vineetha, Childs Peter G, Dalby Matthew J, Salmeron-Sanchez Manuel; Materials Science and Engineering C Vol 113 (2020); https://doi.org/10.1016/j.msec.2020.110966
Nanovibrational stimulation of mesenchymal stem cells induces therapeutic reactive oxygen species and inflammation for three-dimensional bone tissue engineering: Orapiriyakul Wich, Tsimbouri Monica P, Childs Peter, Campsie Paul, Wells Julia, Fernandez-Yague Marc A, Burgess Karl, Tanner K Elizabeth, Tassieri Manlio, Meek Dominic, Vassalli Massimo, Biggs Manus J P, Salmerón-Sánchez Manuel, Oreffo Richard O C, Reid Stuart, Dalby Matthew J; ACS Nano Vol 14, pp. 10027-10044 (2020); https://doi.org/10.1021/acsnano.0c03130
Reduction of pseudomonas aeruginosa biofilm formation through the application of nanoscale vibration: Robertson Shaun N, Childs Peter G, Akinbobola Ayorinde, Henriquez Fiona L, Ramage Gordon, Reid Stuart, Mackay William G, Williams Craig; Journal of Bioscience and Bioengineering Vol 129, pp. 379-386 (2020); https://doi.org/10.1016/j.jbiosc.2019.09.003
Design, construction and characterisation of a novel nanovibrational bioreactor and cultureware for osteogenesis: Campsie Paul, Childs Peter G, Robertson Shaun N, Cameron Kenny, Hough James, Salmeron-Sanchez Manuel, Tsimbouri Penelope M, Vichare Parag, Dalby Matthew J, Reid Stuart; Scientific Reports Vol 9 (2019); https://doi.org/10.1038/s41598-019-49422-4

More publications

Professional activities

Therapeutic refinement of tissue engineered cellular implants for non-union fracture repair: Speaker; 11/12/2020

More professional activities

Projects

Selective stem cell engineering through tuned mechanical loads: Childs, Peter (Principal Investigator); 31-Jan-2021 - 30-Jan-2022
Healikick - A Combined Atmp Strategy To Supplement Critical Sized Bone Fracture Healing: Reid, Stuart (Principal Investigator) Childs, Peter (Co-investigator); 01-Jan-2020 - 30-Jan-2025

Address

Biomedical Engineering
Wolfson Building

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