Dr Peter Childs

Strathclyde Chancellor's Fellow

Biomedical Engineering

Personal statement

I am a Chancellors Fellow within the Department of Biomedical Engineering. My research interests include the control of cell function/fate through applied mechanical stimulation and development of materials for tissue regeneration (cellular and acellular). Since 2012 I have been involved with a multidisciplinary collaboration using nano amplitude vibration to stimulate stem cell osteogenesis ('nanokicking'). This technology is now being translated towards clinic as an osteogenic cell therapy for orthopaedic repair. I have also been involved in the translation of implantable bioactive polymers for growth factor delivery ('HealiOst'). Previously I was awarded a Royal Society of Edinburgh Enterprise Fellowship and have a keen interest in the clinical/commercial translation of cell engineering technologies.

Publications

Tissue engineered mimetic periosteum for efficient delivery of rhBMP-2: Romero-Torrecilla Juan Antonio, Muinos-Lopez Emma, Valdés-Fernández José, López-Martínez Tania, Ripalda-Cemboráin Purificación, Jayawarna Vineetha, Childs Peter, Salmeron-Sanchez Manuel, Prósper Felipe, Granero-Moltó Froilán; 49th European Calcified Tissue Society Congress (2022); https://doi.org/10.1016/j.bonr.2022.101252
Changes of nuclear and cellular properties following nanovibration of 3T3 fibroblastic cells: Johnson-Love Olivia, Campsie Paul, Reid Stuart, Espinosa Francisco, Garcia Ricardo, Dalby Matthew, Childs Peter; Future Investigators of Regenerative Medicine (2022)
Materials-driven fibronectin assembly on nanoscale topography enhances mesenchymal stem cell adhesion, protecting cells from bacterial virulence factors and preventing biofilm formation: Damiati Laila A, Tsimbouri Monica P, Hernandez Virginia-Llopis, Jayawarna Vineetha, Ginty Mark, Childs Peter, Xiao Yinbo, Burgess Karl, Wells Julia, Sprott Mark R, Meek R M Dominic, Li Peifeng, Oreffo Richard O C, Nobbs Angela, Ramage Gordon, Su Bo, Salmeron-Sanchez Manuel, Dalby Matthew J; Biomaterials Vol 280 (2022); https://doi.org/10.1016/j.biomaterials.2021.121263
Nanovibrational stimulation inhibits osteoclastogenesis and enhances osteogenesis in co-cultures: Kennedy John W, Tsimbouri Monica P, Campsie Paul, Sood Shatakshi, Childs Peter G, Reid Stuart, Young Peter S, Meek Dominic R M, Goodyear Carl S, Dalby Matthew J; Scientific Reports Vol 11 (2021); https://doi.org/10.1038/s41598-021-02139-9
The use of nanovibration to discover specific and potent bioactive metabolites that stimulate osteogenic differentiation in mesenchymal stem cells: Hodgkinson Thomas, Monica Tsimbouri P, Llopis-Hernandez Virginia, Campsie Paul, Scurr David, Childs Peter G, Phillips David, Donnelly Sam, Wells Julia, Salmerón-Sánchez Manuel, Burgess Karl E V, Alexander Morgan, Vassalli Massimo, Oreffo Richard, Reid Stuart, France David J, Dalby Matthew J; Science Advances Vol 7 (2021); https://doi.org/10.1126/sciadv.abb7921
Tissue engineered scaffolds for mimetic autografts: Romero-Torrecilla Juan Antonio, Riera Luis, Valdés-Fernández José, López-Martínez Tania, Ripalda-Cemboráin Purificación, Jayawarna Vineetha, Childs Peter, Salmeron-Sanchez Manuel, Prósper-Cardoso Felipe, Granero-Moltó Froilán; ECTS 2020, pp. 11 (2020); https://doi.org/10.1016/j.bonr.2020.100386

More publications

Professional activities

PhD examination: Examiner; 29/7/2022
Cellular Mechanotransduction: Using vibration to manufacture a cellular ATMP: Speaker; 15/3/2022
SULSA Our Future Health Innovation Fund Workshop: Participant; 25/2/2022
Biomedical Engineering (Organisational unit): Advisor; 7/12/2021
Preclinical translation of mesenchymal stem cell therapies: Speaker; 10/2021
MRes examination: Examiner; 1/9/2021

More professional activities

Projects

BRAINS Strathclyde Centre for Doctoral Training: MacKenzie, Lewis (Principal Investigator) Childs, Peter (Principal Investigator) Witte, Kimia (Principal Investigator) Jimenez, Melanie (Principal Investigator) Chow, Shiao (Principal Investigator) Fu, Ying (Principal Investigator) Gomez-Roman, Natividad (Principal Investigator) Fazio, Mariana (Principal Investigator) Reid, Andrew Baxter (Principal Investigator); Centre for Doctoral Training in Bridging Research and Advancements in Neurological Sciences (BRAINS). First cohort of PhD students starting autumn 2023.; 01-Jan-2023
DTP 2224 University of Strathclyde | Pereira Sousa, Rui Pedro: Childs, Peter (Principal Investigator) Jimenez, Melanie (Co-investigator) Pereira Sousa, Rui Pedro (Research Co-investigator); 01-Jan-2022 - 01-Jan-2026
EPSRC REA - Mechanosensitivity of osteoporotic stem cells for diagnosis and treatment of osteoporosis: Childs, Peter (Principal Investigator) Jimenez, Melanie (Co-investigator); 01-Jan-2022 - 31-Jan-2026
Development of a new model of human vascular calcification: Wu, Junxi (Principal Investigator) Childs, Peter (Co-investigator); 15-Jan-2022 - 15-Jan-2022
Mechanobiology-based medicine: Childs, Peter (Principal Investigator); 01-Jan-2021 - 31-Jan-2022
Selective stem cell engineering through tuned mechanical loads: Childs, Peter (Principal Investigator); 31-Jan-2021 - 30-Jan-2022

More projects

Address

Biomedical Engineering
Wolfson

Location Map

View University of Strathclyde in a larger map