Dr Susan Currie

Reader

Strathclyde Institute of Pharmacy and Biomedical Sciences

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Personal statement

Susan Currie obtained her PhD in Biochemistry (cellular signalling and molecular pharmacology) from the University of Glasgow in 1992 then spent two years at Lilly Research Laboratories, USA, where she studied the role of phospholipase A² in mast cell activation. She returned to the University of Glasgow in 1994 to join the then newly formed Clinical Research Initiative in heart disease and became a founder member of the school of cardiovascular studies in Glasgow. During this time she progressed from postdoctoral researcher to Principal Investigator examining the role of Calcium/calmodulin protein kinase ll (CaMKll) in cardiac hypertrophy and heart failure. She moved to the University of Strathclyde in 2005 as a Lecturer in Physiology & Pharmacology and established an independent cardiovascular signalling research group with principal interests in CaMKll modulation of cardiac calcium handling and cardiac inflammation. She is currently an Associate Professor/Reader within Strathclyde Institute of Pharmacy & Biomedical Sciences and CaMKll as a therapeutic target in cardiac disease remains a key focus of research. More recent research interests include cardiotoxicity in the context of safety pharmacology and devices as well as altered cardiovascular function in ageing and Heart Failure with Preserved Ejection Fraction (HFpEF).

Susan has been research group leader for the Cellular Basis of Disease research group within Strathclyde Institute of Pharmacy & Biomedical Sciences (2021-2023). Externally she was chair of the Scottish Cardiovascular Forum for 12 years (2011-2023). She currently sits on the committee for the British Society of Cardiovascular Research and is an elected Fellow of the Physiological Society. Fellowship was awarded in 2017 in recognition of her contribution to cardiovascular research and the discipline of Physiology. More recently (2024), she has also been elected as a Fellow of the Royal Society of Biology, signifying her international standing in the field of Biological Sciences. She sits on the editorial boards for a range of scientific journals and regularly reviews research funding applications for a number of research councils and charities. She currently teaches on a wide range of classes across both the MPharm and Biomedical Sciences programmes at the University of Strathclyde and coordinates classes on the MPharm programme. She was awarded Fellowship of the Higher Education Academy in 2008.

Susan previously directed the collaborative MPharm programme between the University of Strathclyde and the International Medical University (IMU) in Kuala Lumpur (2012-2017), acting as MPharm representative on the internationalisation committee and was Deputy Director of the MPharm programme at the University of Strathclyde (2012-2018). She is currently Director of Equality, Diversity and Inclusion within Strathclyde Institute of Pharmacy & Biomedical Sciences.

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Publications

From freeze to function : optimised cryopreservation and mitochondrial analysis workflow for skeletal muscle biopsies
Wahid Maheen, Mackenzie Graeme, Rooney Liam M, Greig Justin C, McConnell Gail, Combet Emilie, Gray Stuart, Murray James T, Currie Susan, Gould Gwyn W, Cunningham Margaret R
BMC Methods Vol 1 (2024)
https://doi.org/10.1186/s44330-024-00017-0
A novel 3D imaging approach for quantification of GLUT4 levels across the intact myocardium
Geiser Angéline, Currie Susan, Al-Hasani Hadi, Chadt Alexandra, McConnell Gail, Gould Gwyn W
Journal of Cell Science Vol 137 (2024)
https://doi.org/10.1242/jcs.262146
Altered regulation of Ca2+ handling proteins in an in vivo rat model of Angiotensin II-induced hypertension
Olatunji Zainab, BOSAKHAR Zainab Y H A H A, MacKenzie Graeme, Cunningham Margaret Rose, MacQuaide Niall, Currie Susan
Medical Science Forum Vol 27 (2024)
https://doi.org/10.3390/msf2024027003
Acute effects of cobalt on calcium handling in cardiac myocytes
Cameron-Ruiz Miren, Olatunji Zainab, MacQuaide Niall, Currie Susan
Joint BAS/BSCR meeting at annual BCS conference 2024 (2024)
CaMKII augments ROS and Ca2+ entry processes in female cardiac fibroblasts in hyperglycaemic and hypertensive conditions
Olatunji Zainab, Currie Susan, MacQuaide Niall
Joint BAS/BSCR meeting at annual BCS conference 2024 (2024)
CaMKII augments ROS and Ca2+ entry processes in female cardiac fibroblasts in hyperglycemic and hypertensive conditions
Olatunji Zainab, Currie Susan, MacQuaide Niall
Heart Vol 110 (2024)
https://doi.org/10.1136/heartjnl-2024-BCS.268

More publications

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Professional Activities

48th meeting of EWGCCE
Participant
1/7/2024
Joint BAS/BSCR meeting at annual BCS conference 2024
Organiser
3/6/2024
Joint BAS/BSCR meeting at annual BCS conference 2024
Chair
3/6/2024
Understanding mitochondrial changes in chemotherapy-induced cardiac damage
Examiner
4/2024
Preclinical cardiac safety screening: exploring and developing work-loop models to identify drug-induced changes in contractility
Examiner
29/2/2024
27th annual meeting of the Scottish Cardiovascular Forum
Participant
3/2/2024

More professional activities

Projects

Investigating cobalt cardiotoxicity in contractile and non-contractile cells of the heart
Currie, Susan (Principal Investigator) MacQuaide, Niall (Research Co-investigator)
08-Jan-2024 - 07-Jan-2027
Investigating Cobalt Cardio toxicity in Contractile and non contractile cells of the heart
Currie, Susan (Principal Investigator)
08-Jan-2024 - 07-Jan-2027
Heart Damage Caused by Cancer and Anti-cancer Drugs (Vacation Scholarship)
Cunningham, Margaret Rose (Principal Investigator) Bauer, Ralf (Co-investigator) Currie, Susan (Co-investigator)
27-Jun-2022 - 19-Aug-2022
Remodelling of E-C coupling in heart failure with preserved ejection fraction (HFpEF)
Currie, Susan (Co-investigator)
01-Oct-2021 - 30-Sep-2024
Cross-examining interplay between High Mobility Group Box 1 (HMGB1) and coagulation: Defining a role for G protein-coupled receptors (GPCRs) in this complex Coag-Inflammatory nexus
BOSAKHAR, Zainab Y H A H A (Post Grad Student) Currie, Susan (Co-investigator) Plevin, Robin (Academic) Cunningham, Margaret Rose (Principal Investigator)
01-Dec-2020 - 30-Nov-2023
Doctoral Training Partnership 2020-2021 University of Strathclyde | Geiser, Angeline
Gould, Gwyn (Principal Investigator) Currie, Susan (Co-investigator) Geiser, Angeline (Research Co-investigator)
01-Oct-2020 - 14-Nov-2024

More projects

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Contact

Dr Susan Currie
Reader
Strathclyde Institute of Pharmacy and Biomedical Sciences

Email: susan.currie@strath.ac.uk
Tel: 548 2405