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Dr Susan Currie

Senior Lecturer

Strathclyde Institute of Pharmacy and Biomedical Sciences

Personal statement

Susan Currie obtained her PhD in Biochemistry (cellular signalling and molecular pharmacology) from the University of Glasgow in 1992 then spent two years at Lilly Research Laboratories, USA, where she studied the role of phospholipase A┬▓ in mast cell activation. She returned to the University of Glasgow in 1994 to join the then newly formed Clinical Research Initiative in heart disease and became a founder member of the school of cardiovascular studies in Glasgow. During this time she progressed from postdoctoral researcher to Principal Investigator examining the role of Calcium/calmodulin protein kinase ll (CaMKll) in cardiac hypertrophy and heart failure. She moved to the University of Strathclyde in 2005 as a Lecturer in Physiology & Pharmacology and established an independent cardiovascular signalling research group with principal interests in CaMKll modulation of cardiac calcium handling and cardiac inflammation. CaMKll as a therapeutic target in cardiac disease remains a key focus of research and characterising the actions of this enzyme is ongoing. More recent research interests include cardiotoxicity in the context of safety pharmacology as well as altered cardiovascular function in ageing.

Dr Currie is currently chair of the Scottish Cardiovascular Forum and full member of the Physiological Society and Biophysical Society, as well as being the Strathclyde University representative for the Physiological Society. She was made a Fellow of the Physiological Society in 2017 in recognition of her contribution to cardiovascular research and the discipline of Physiology. She currently teaches on a wide range of classes across both the MPharm and Biomedical Sciences programmes at the University of Strathclyde and coordinates classes on the MPharm programme. She was awarded Fellowship of the Higher Education Academy in 2008. She currently co-directs the collaborative MPharm programme between the University of Strathclyde and the International Medical University (IMU) in Kuala Lumpur, acting as MPharm representative on the internationalisation committee and is Deputy Director of the MPharm programme at the University of Strathclyde.

Publications

Anti-cancer tyrosine kinase inhibitors increase oxidative stress in primary cardiac fibroblasts
McMullen CJ, McCluskey C, Kim SJ, Laovitthayanggoon S, MacDonald M, Safar M, Wood R, Cunningham MR, Currie S
British Heart Journal Vol 104, (2018)
http://dx.doi.org/10.1136/heartintjnl-2018-SCF22
Parallel assessment of cell viability in cardiac and cancer cells following treatment with sunitinib
McBride Domenica, ALHAZMI Abdulfattah Yahya M, Laovitthayanggoon Sarunya, Boyd Marie, Currie Susan
British Heart Journal Vol 104, (2018)
http://dx.doi.org/10.1136/heartjnl-2018-SCF.16
Changes in IP3 receptor expression and function in aortic smooth muscle of atherosclerotic mice
Ewart Marie-ann, Ugusman Azizah, Vishwanath Anisha, Almabrouk Tarek A.M., Alganga Husman, Katwan Omar J., Hubanova Pavlina , Currie Susan, Kennedy Simon
Journal of Vascular Research Vol 54, (2017)
http://dx.doi.org/10.1159/000461581
In vivo and in vitro toxicity of cobalt in the heart
Laovitthayanggoon Sarunya, Henderson Catherine J., Tate Rothwelle J., Currie Susan, McCluskey Claire, Macdonald Margaret, Grant M. Helen
British Toxicology Society Congress 2017, (2017)
In vitro effects of cobalt ions on CNS derived cell lines
Gomez Arnaiz Sara, Tate Rothwelle, Currie Susan, Grant Mary
British Toxicology Society Congress 2017, (2017)
Ageing of the vascular endothelium : a novel role for CaMKII╬┤
McCluskey Claire, Macdonald Margaret, Currie Susan
British Heart Journal Vol 103, pp. A2, (2017)
http://dx.doi.org/10.1136/heartjnl-2017-311433.3

more publications

Projects

AWERB 3Rs grant 2016
Cunningham, Margaret Rose (Co-investigator) Currie, Susan (Principal Investigator)
Period 01-Aug-2016
BB/J013854/1 BBSRC DPT Studentships (with Glasgow University) | McCluskey, Claire
Currie, Susan (Principal Investigator) Paul, Andrew (Co-investigator) McCluskey, Claire (Research Co-investigator)
Period 01-Oct-2013 - 01-Oct-2017
BBSRC Doctoral Training Grant (DTG) | MacAskill, Mark
Coats, Paul (Principal Investigator) Currie, Susan (Co-investigator)
Period 01-Oct-2010 - 08-Apr-2014
Development of starting materials for cell-based treatments (project plan for SMART grant)
Carswell, Hilary (Principal Investigator) Carter, Katharine (Co-investigator) Currie, Susan (Co-investigator) Pickard, Benjamin (Co-investigator)
Period 01-Apr-2015 - 31-Mar-2016
Phosphatase regulation of the cardiac ryanodine receptor in normal and failing rabbit hearts
Currie, Susan (Principal Investigator)
Period 01-Jan-2005 - 01-Jan-2008
BBSRC RESEARCH EXPERIENCE PLACEMENTS 2010
Carter, Katharine (Principal Investigator) Currie, Susan (Co-investigator) Edrada-Ebel, Ruangelie (Co-investigator)
Period 01-Jul-2010 - 31-Aug-2010

more projects

Address

Strathclyde Institute of Pharmacy and Biomedical Sciences
Hamnett Wing John Arbuthnott Building

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