Publications

A point-of-care diagnostic for drug-induced liver injury using surface-enhanced Raman scattering lateral flow immunoassay

Sloan-Dennison Sian, Scullion Kathleen M, Clark Benjamin, Fineran Paul, Mair Joanne, Laing Stacey, Shand Neil, Rathmell Cicely, Creasey David, Bingemann Dieter, Faircloth Jonathan, Zeig Mark, Weir Christopher J, Dear James W, Faulds (She/Her) Karen, Graham Duncan

Nature Communications Vol 16 (2025)

https://doi.org/10.1038/s41467-025-61600-9

Unmixing hyperspectral SRS images in the cell-silent region of the Raman spectrum using phasor analysis

Tipping William J, Gould Gwyn W, Faulds (She/Her) Karen, Graham Duncan

Chemical & Biomedical Imaging (2025)

https://doi.org/10.1021/cbmi.5c00023

Alkyne-tag Raman imaging and sensing of bioactive compounds

Dodo Kosuke, Tipping William J, Yamakoshi Hiroyuki, Egoshi Syusuke, Kubo Toshiki, Kumamoto Yasuaki, Faulds Karen, Graham Duncan, Fujita Katsumasa, Sodeoka Mikiko

Nature Reviews Methods Primers Vol 5 (2025)

https://doi.org/10.1038/s43586-025-00389-9

Surface enhanced Raman scattering for biomolecular sensing in human healthcare monitoring

Laing Stacey, Sloan-Dennison Sian, Faulds Karen, Graham Duncan

ACS Nano Vol 19, pp. 8381-8400 (2025)

https://doi.org/10.1021/acsnano.4c15877

Uncovering the vibrational modes of zwitterion glycine in aqueous solution

Christie Mark, Mohammadpour Mozhdeh, Sefcik Jan, Faulds Karen, Johnston Karen

Vibrational Spectroscopy Vol 137 (2025)

https://doi.org/10.1016/j.vibspec.2025.103783

Gold nanoparticle-based conjugated nanotags as potential compounds against Trypanosoma brucei infection

Rostán Santiago, Laing Stacey, Girard Alexandre, Scalese Gonzalo, Cooper Anneli, MacLeod Annette, Pérez-Díaz Leticia, Mahler Graciela, Faulds Karen, Graham Duncan, Otero Lucía

ACS Applied Nano Materials Vol 7, pp. 28219-28228 (2024)

https://doi.org/10.1021/acsanm.4c05201

More publications

Research Interests

Our research focuses on using surface enhanced Raman scattering (SERS) to create new approaches to bioanalysis for use in the life and clinical sciences.  SERS is a spectroscopic technique that offers significant advantages over other established techniques such as fluorescence and our research has focused on highlighting the advantages, creating new examples of increased capability in life science applications and interacting with end users to shape future step changes in research.  Our research centres around using the inherent sensitivity of SERS for the detection of target DNA or proteins using signal amplification methods to enhance the signal rather than using target amplification methods such as PCR.  Our work has focussed on exploiting the sensitivity of SERS for quantitative analysis of biomolecules as well as exploiting one of the key advantages of SERS, the ability to analyse multiple analytes in one sample.  This allows more information to be gained per analysis as well as giving information about complex systems that are intrinsically difficult to measure.

Professional Activities

Development of a Spatially Offset Raman Spectroscopy Probe for Monitoring Pharmaceutical Drying

Contributor

25/1/2024

Development of a Spatially Resolved Spectroscopy probe for In-line Monitoring of Pharmaceutical Drying

Contributor

21/3/2023

Seminar

Invited speaker

11/2022

SciX 2022

Invited speaker

10/2022

SciX 2022

Keynote/plenary speaker

10/2022

Seminar

Invited speaker

9/2022

More professional activities

Projects

Combined photodynamic and photothermal therapy of breast cancer

Edkins, Robert (Principal Investigator) Faulds, Karen (Co-investigator)

01-Jan-2025 - 31-Jan-2028

Rapid Detection of Pathogens in the Food Production Environment

Faulds, Karen (Principal Investigator) Graham, Duncan (Co-investigator)

03-Jan-2025 - 15-Jan-2026

Industrial CASE Account - University of Strathclyde 2024 | Whyte, Ryan

Tomkinson, Nick (Principal Investigator) Faulds, Karen (Co-investigator) Whyte, Ryan (Research Co-investigator)

01-Jan-2024 - 01-Jan-2028

Non-invasive single cell metabolic studies in adipocytes CT23-6

Gould, Gwyn (Principal Investigator) Faulds, Karen (Co-investigator) Tomkinson, Nick (Co-investigator)

01-Jan-2024 - 30-Jan-2027

Development of Point of Use Bionanosensors (co-funded PhD )

Faulds, Karen (Principal Investigator) Graham, Duncan (Co-investigator)

01-Jan-2024 - 31-Jan-2028

DTP 2224 University of Strathclyde | Didio, Rocco

Graham, Duncan (Principal Investigator) Faulds, Karen (Co-investigator) Didio, Rocco (Research Co-investigator)

01-Jan-2024 - 01-Jan-2028

More projects