Dr Natividad Gomez-Roman

Senior Lecturer

Strathclyde Institute of Pharmacy and Biomedical Sciences

Contact

Personal statement

Our work aims to understand the tumour biology of brain and ovarian cancers, which will help us identify novel treatments resulting in improved patient outcomes. We pursue this by developing experimental models of disease that recapitulate the clinical environment, including three-dimensional cell culture systems using scaffolds, organoid and ex-vivo models and in vivo models of disease.

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Publications

Human iPSC-derived cerebral organoids as a translational model for stroke and preclinical therapeutic screening
Omerigwe Simon Achi, Gomez-Roman Natividad, Newton Kathryn, Bowles Kathryn R, Carswell Hilary
SIPBS Postgraduate Research Day 2025 (2025)
P12.58.a - Role of Il-33/ST2 axis in glioblastoma development and its response to treatment
Zhao F, Rominiyi O, Collis S, Jiang H, Gomez-Roman N
Neuro-Oncology Vol 27, pp. iii130-iii130 (2025)
https://doi.org/10.1093/neuonc/noaf193.437
P01.47.a - Impact of cholesterol synthesis inhibition in G7 glioblastoma stem-like cells cultured as 3D spheroids
Mirza S, Gomez-Roman N
Neuro-Oncology Vol 27, pp. iii41-iii41 (2025)
https://doi.org/10.1093/neuonc/noaf193.127
Human iPSC-Derived Cerebral Organoids for In Vitro Stroke Modelling and Therapeutic Testing
Omerigwe Simon Achi, Gomez-Roman Natividad, Newton Kathryn, Bowles Kathryn R, Carswell Hilary
7th UK Preclinical Stroke Symposium, pp. 45-46 (2025)
Ex-vivo models of post-surgical residual disease in human glioblastoma
Rominiyi Ola, McGarrity-Cottrell Connor, Myers Katie, Jones Callum, Wosnitzka Kelsey, Williams Sophie T, Vanderlinden Aurelie, Antohj Andra-Gabriela, Gomez-Roman Natividad, Chalmers Anthony J, Sinha Saurab, Carrol Thomas A, Wang Dennis, Cavalli Andrea, Bagga Veejay, Al-Tamimi Yahia, Dunning Mark J, Collis Spencer J
F1000Research Vol 13 (2024)
https://doi.org/10.12688/f1000research.157013.1
P13.06. A evaluation of BBB permeable WEE1 and CHK1 inhibitors in combination with standard of care for the treatment of Glioblastoma
Scholefield E L, Gomez-Roman N
Neuro-Oncology Vol 26, pp. v72-v72 (2024)
https://doi.org/10.1093/neuonc/noae144.239

More publications

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Professional Activities

Targeting cholesterol metabolism to overcome radiation resistance in glioblastoma
Speaker
19/10/2024
VIVA (PhD) - internal examiner
Examiner
23/5/2024
How does radiation affect cell metabolism?
Speaker
3/5/2024
European Society for Radiotherapy and Oncology
Participant
3/5/2024
Molecular Oncology (Journal)
Peer reviewer
12/12/2023
Expanding Theories call
Advisor
10/12/2023

More professional activities

Projects

Investigating the role of obesity and fatty acids in promoting GBM survival
Gammoh, Noor (Principal Investigator) Gomez-Roman, Natividad (Co-investigator) Banerjee, Sourav (Co-investigator)
CRUK Scotland Centre - Edinburgh Cancer Research Funded Studentships
01-Jan-2025 - 30-Jan-2029
Cancer-Targeting Upconversion Nanoparticles to Track-and-Treat Glioblastoma
MacKenzie, Lewis (Principal Investigator) Chow, Shiao (Co-investigator) Gomez-Roman, Natividad (Co-investigator)
01-Jan-2025 - 31-Jan-2027
Investigating neurotransmitter-mediated tumour microenvironment in glioblastoma
Li, Jianbin (Post Grad Student) Gomez-Roman, Natividad (Principal Investigator)
01-Jan-2024 - 30-Jan-2027
Exploring nanoscale mechanical stimulation as a novel therapeutic avenue for hard-to-treat brain cancers
Gomez-Roman, Natividad (Principal Investigator)
01-Jan-2024 - 30-Jan-2025
Characterising cholesterol trafficking in glioblastoma and brain cells, and its contribution to tumour development, progression and treatment resistance
Gomez-Roman, Natividad (Principal Investigator)
01-Jan-2024 - 31-Jan-2027
Development of A Novel Non-Animal Research Method for Glioblastoma Research
Gomez-Roman, Natividad (Principal Investigator)
22-Jan-2024 - 30-Jan-2024

More projects

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Contact

Dr Natividad Gomez-Roman
Senior Lecturer
Strathclyde Institute of Pharmacy and Biomedical Sciences

Email: natividad.gomez-roman@strath.ac.uk
Tel: 548 2122