Dr Natividad Gomez-Roman

Senior Lecturer

Strathclyde Institute of Pharmacy and Biomedical Sciences

Contact

Personal statement

Our work aims to understand the tumour biology of brain and ovarian cancers, which will help us identify novel treatments resulting in improved patient outcomes. We pursue this by developing experimental models of disease that recapitulate the clinical environment, including three-dimensional cell culture systems using scaffolds, organoid and ex-vivo models and in vivo models of disease.

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Publications

Ex-vivo models of post-surgical residual disease in human glioblastoma
Rominiyi Ola, McGarrity-Cottrell Connor, Myers Katie, Jones Callum, Wosnitzka Kelsey, Williams Sophie T, Vanderlinden Aurelie, Antohj Andra-Gabriela, Gomez-Roman Natividad, Chalmers Anthony J, Sinha Saurab, Carrol Thomas A, Wang Dennis, Cavalli Andrea, Bagga Veejay, Al-Tamimi Yahia, Dunning Mark J, Collis Spencer J
F1000Research Vol 13 (2024)
https://doi.org/10.12688/f1000research.157013.1
P13.06. A evaluation of BBB permeable WEE1 and CHK1 inhibitors in combination with standard of care for the treatment of Glioblastoma
Scholefield E L, Gomez-Roman N
Neuro-Oncology Vol 26, pp. v72-v72 (2024)
https://doi.org/10.1093/neuonc/noae144.239
ClonoScreen3D – a novel three-dimensional clonogenic screening platform for identification of radiosensitizers for glioblastoma
Jackson Mark R, Richards Amanda R, Ayoola Oladipupo Abdul-Basit, Chahal Sandeep K, Carager Seamus, Chalmers Anthony J, Gomez-Roman Natividad
International Journal of Radiation Oncology - Biology - Physics Vol 120, pp. 162-177 (2024)
https://doi.org/10.1016/j.ijrobp.2024.02.046
A joint physics and radiobiology DREAM team vision - towards better response prediction models to advance radiotherapy
Vens C, van Luijk P, Vogelius RI, El Naqa I, Humbert-Vidan L, von Neubeck C, Gomez-Roman N, Bahn E, Brualla L, Böhlen TT, Ecker S, Koch R, Handeland A, Pereira S, Possenti L, Rancati T, Todor D, Vanderstraeten B, Van Heerden M, Ullrich W, Jackson M, Alber M, Marignol L
Radiotherapy and Oncology Vol 196 (2024)
https://doi.org/10.1016/j.radonc.2024.110277
ClonoScreen3D : a novel three-dimensional clonogenic screening platform for identification of radiosensitizers for glioblastoma
Jackson Mark R, R Richards Amanda, Ayoola Oladipupo Abdul-Basit, Chahal Sandeep K, Carager Seamus, Chalmers Anthony J, Gomez-Roman Natividad
(2023)
https://doi.org/10.1101/2023.10.04.560635
Evaluating the enhancement of cell kill by radiation therapy through novel wee1 inhibitors with improved brain permeability in the treatment of glioblastoma
Scholefield Emma, Gomez-Roman Natividad
Cancer Research UK - Association for Radiation Research Conference (2023)

More publications

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Professional Activities

Targeting cholesterol metabolism to overcome radiation resistance in glioblastoma
Speaker
19/10/2024
VIVA (PhD) - internal examiner
Examiner
23/5/2024
How does radiation affect cell metabolism?
Speaker
3/5/2024
European Society for Radiotherapy and Oncology
Participant
3/5/2024
Molecular Oncology (Journal)
Peer reviewer
12/12/2023
Expanding Theories call
Advisor
10/12/2023

More professional activities

Projects

Investigating neurotransmitter-mediated tumour microenvironment in glioblastoma
Li, Jianbin (Post Grad Student) Gomez-Roman, Natividad (Principal Investigator)
01-Jan-2024 - 30-Jan-2027
Exploring nanoscale mechanical stimulation as a novel therapeutic avenue for hard-to-treat brain cancers
Gomez-Roman, Natividad (Principal Investigator)
01-Jan-2024 - 30-Jan-2025
Characterising cholesterol trafficking in glioblastoma and brain cells, and its contribution to tumour development, progression and treatment resistance
Gomez-Roman, Natividad (Principal Investigator)
01-Jan-2024 - 31-Jan-2027
Development of A Novel Non-Animal Research Method for Glioblastoma Research
Gomez-Roman, Natividad (Principal Investigator)
22-Jan-2024 - 30-Jan-2024
Exploring Cholesterol Metabolism, Lipid Droplets, and NPC Dysfunction in Cellular Health and Disease
Gomez-Roman, Natividad (Principal Investigator) Hutchison, Amber (Researcher)
The project aims to address the connection between cholesterol metabolism, lipid droplets and
NPC dysfunction in glioblastoma cells to uncover a novel therapeutic intervention that exploits lipid metabolism in cancer cells
10-Jan-2024 - 12-Jan-2024
Exploring the Reversed Blood-Brain Barrier
Witte, Kimia (Principal Investigator) Gomez-Roman, Natividad (Co-investigator)
01-Jan-2023 - 31-Jan-2024

More projects

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Contact

Dr Natividad Gomez-Roman
Senior Lecturer
Strathclyde Institute of Pharmacy and Biomedical Sciences

Email: natividad.gomez-roman@strath.ac.uk
Tel: 548 2122