Personal statement

Our work aims to understand the tumour biology of brain and ovarian cancers, which will help us identify novel treatments resulting in improved patient outcomes. We pursue this by developing experimental models of disease that recapitulate the clinical environment, including three-dimensional cell culture systems using scaffolds, organoid and ex-vivo models and in vivo models of disease.

Prizes and awards

CRUK RadNet CRISPR Workshop Travel Bursary: Recipient; 14/6/2022

More prizes and awards

Publications

Abstract PO-017 : radiotherapy in combination with the brain penetrant ATM inhibitor AZD1390 does not exacerbate radiation toxicity of neural stem cells in vitro or in vivo: Guttierez-Quintana Rodrigo, Walker David J, Jackson Mark R, Gomez-Roman Natividad, Chahal Sandeep, Durant Stephen T, Chalmers Anthony J; Clinical Cancer Research Vol 27 (2021); https://doi.org/10.1158/1557-3265.radsci21-po-017
Quantitative in vivo bioluminescence imaging of orthotopic patient-derived glioblastoma xenografts: Koessinger Anna L, Koessinger Dominik, Stevenson Katrina, Cloix Catherine, Mitchell Louise, Nixon Colin, Gomez-Roman Natividad, Chalmers Anthony J, Norman Jim C, Tait Stephen W G; Scientific Reports Vol 10 (2020); https://doi.org/10.1038/s41598-020-72322-x
Radiation responses of 2D and 3D glioblastoma cells : a novel, 3D-specific radioprotective role of VEGF/Akt signaling through functional activation of NHEJ: Gomez-Roman Natividad, Chong Ming Y, Chahal Sandeep K, Caragher Seamus P, Jackson Mark R, Stevenson Katrina H, Dongre Sidhartha A, Chalmers Anthony J; Molecular Cancer Therapeutics Vol 19, pp. 575-589 (2020); https://doi.org/10.1158/1535-7163.MCT-18-1320
Patient-specific 3D-printed glioblastomas: Gomez-Roman Natividad, Chalmers Anthony J; Nature Biomedical Engineering Vol 3, pp. 498-499 (2019); https://doi.org/10.1038/s41551-019-0379-2
Glioblastoma's next top model : novel culture systems for brain cancer radiotherapy research: Caragher Seamus, Chalmers Anthony J, Gomez-Roman Natividad; Cancers Vol 11 (2019); https://doi.org/10.3390/cancers11010044
Replication stress drives constitutive activation of the DNA damage response and radioresistance in glioblastoma stem-like cells: Carruthers Ross D, Ahmed Shafiq U, Ramachandran Shaliny, Strathdee Karen, Kurian Kathreena M, Hedley Ann, Gomez-Roman Natividad, Kalna Gabriela, Neilson Mathew, Gilmour Lesley, Stevenson Katrina H, Hammond Ester M, Chalmers Anthony J; Cancer Research Vol 78, pp. 5060-5071 (2018); https://doi.org/10.1158/0008-5472.CAN-18-0569

More publications

Professional activities

ESTRO - Radiobiology Workshop: Participant; 7/10/2022
Modelling glioblastoma responses to drug-radiation combination treatments: Speaker; 18/7/2022
Modelling treatment response of drug-radiation combinations in glioblastoma: Speaker; 22/6/2022
CRISPR in Radiation Research Workshop: Participant; 14/6/2022
The Journal of Pathology Clinical Research (Journal): Peer reviewer; 1/5/2022
Gliomodel (External organisation): Advisor; 1/4/2022

More professional activities

Projects

BRAINS Strathclyde Centre for Doctoral Training: MacKenzie, Lewis (Principal Investigator) Childs, Peter (Principal Investigator) Witte, Kimia (Principal Investigator) Jimenez, Melanie (Principal Investigator) Chow, Shiao (Principal Investigator) Fu, Ying (Principal Investigator) Gomez-Roman, Natividad (Principal Investigator) Fazio, Mariana (Principal Investigator) Reid, Andrew Baxter (Principal Investigator); Centre for Doctoral Training in Bridging Research and Advancements in Neurological Sciences (BRAINS). First cohort of PhD students starting autumn 2023.; 01-Jan-2023
Developing Aberdeen's Cancer Research Network: Spiers, Valerie (Principal Investigator) kiltie, anne (Principal Investigator) Gomez-Roman, Natividad (Co-investigator) Boyd, Marie (Co-investigator) Tomlinson, Ian P M (Principal Investigator) Gourley, Charlie (Co-investigator) Machesky, Laura (Co-investigator) Chalmers, Anthony (Principal Investigator) Broche, Lionel (Co-investigator) Stansfield, Ian (Co-investigator); The aim of this proposal is to encourage new collaborative research and innovation in these fields, through working with colleagues in the CRUK Scotland Centre based in Edinburgh and Glasgow, broadening the range of cancer research being conducted in Scotland.; 01-Jan-2022 - 30-Jan-2023
Investigating Novel Wee1 and Chk1 Inhibitors with Improved Brain Permeability for the Treatment of Glioblastoma: Gomez-Roman, Natividad (Principal Investigator); SULSA-industrial collaboration evaluating novel brain permeable compounds in 3D glioblastoma model systems; 01-Jan-2022 - 31-Jan-2023
Understanding the role of cholesterol in the survival and treatment resistance of glioblastoma and its feasibility as a druggable target: Gomez-Roman, Natividad (Principal Investigator) Morgan, John (Post Grad Student); 01-Jan-2021 - 30-Jan-2024
Developing more representative laboratory models of the blood-tumour barrier to improve the drug development pipeline for patients with glioblastoma.: Chalmers, Anthony (Principal Investigator) Carruthers, Ross D (Co-investigator) Birch, Joanna (Co-investigator) Smith, Colin (Co-investigator) Ireson, Chistopher (Co-investigator) Brennan, Paul (Co-investigator) Thompson, Gerry (Co-investigator) Gomez-Roman, Natividad (CoI) Salmeron-Sanchez, Manuel (CoI) Brunton, Val (CoI); 01-Jan-2021 - 31-Jan-2024
Investigating cholesterol protection to radiation treatment in glioblastoma: Gomez-Roman, Natividad (Principal Investigator); 01-Jan-2021 - 31-Jan-2023

More projects

Address

Strathclyde Institute of Pharmacy and Biomedical Sciences
Hamnett Wing

Location Map

View University of Strathclyde in a larger map

Dr Natividad Gomez-Roman

Strathclyde Chancellor's Fellow

Strathclyde Institute of Pharmacy and Biomedical Sciences