Dr Natividad Gomez-Roman
Strathclyde Chancellor's Fellow
Strathclyde Institute of Pharmacy and Biomedical Sciences
Personal statement
Personal statement
Our work aims to understand the tumour biology of brain and ovarian cancers, which will help us identify novel treatments resulting in improved patient outcomes. We pursue this by developing experimental models of disease that recapitulate the clinical environment, including three-dimensional cell culture systems using scaffolds, organoid and ex-vivo models and in vivo models of disease.
Back to staff profile
Fellowship of the Higher Education Academy Recipient 7/9/2023 CRUK RadNet CRISPR Workshop Travel Bursary Recipient 14/6/2022 Strathclyde Chancellor's Fellowship Recipient 1/11/2020 Poster Prize, NC3Rs Fellows Meeting Recipient 1/5/2019 Aurora Programme for Professional Development in Women Recipient 1/9/2018 EANO abstract selected for plenary session Recipient 12/5/2016
Prize And Awards
Back to staff profile
Evaluating the enhancement of cell kill by radiation therapy through novel wee1 inhibitors with improved brain permeability in the treatment of glioblastoma Scholefield Emma, Gomez-Roman Natividad Cancer Research UK - Association for Radiation Research Conference (2023) Combined inhibition of the Fanconi anaemia (FA) pathway and ATR promotes R-loop generation and profound radiosensitisation in glioblastoma Rominiyi Ola, Myers Katie, Gomez-Roman Natividad, Jellinek David A, Chalmers Anthony J, Carroll Thomas A, Chen Beining, Al-Tamimi Yahia, Collis Spencer Brain Tumour Research and Treatment Vol S253 (2022) https://doi.org/10.14791/btrt.2022.10.F-1432 O2 : Towards a living biobank of surgically-relevant 3-dimensional glioblastoma stem cell models to evaluate novel therapeutics and interrogate intratumoural heterogeneity Rominiyi Ola, Vanderlinden A, Myers K, Gomez-Roman Natividad, Dar D, Bagga V, Jellinek D A, Chalmers Anthony, Carroll T A, Al-Tamimi Y, Collis S J British Journal of Surgery Vol 108 (2021) https://doi.org/10.1093/bjs/znab117.002 Abstract PO-017 : radiotherapy in combination with the brain penetrant ATM inhibitor AZD1390 does not exacerbate radiation toxicity of neural stem cells in vitro or in vivo Guttierez-Quintana Rodrigo, Walker David J, Jackson Mark R, Gomez-Roman Natividad, Chahal Sandeep, Durant Stephen T, Chalmers Anthony J Clinical Cancer Research Vol 27 (2021) https://doi.org/10.1158/1557-3265.radsci21-po-017 Quantitative in vivo bioluminescence imaging of orthotopic patient-derived glioblastoma xenografts Koessinger Anna L, Koessinger Dominik, Stevenson Katrina, Cloix Catherine, Mitchell Louise, Nixon Colin, Gomez-Roman Natividad, Chalmers Anthony J, Norman Jim C, Tait Stephen W G Scientific Reports Vol 10 (2020) https://doi.org/10.1038/s41598-020-72322-x Radiation responses of 2D and 3D glioblastoma cells : a novel, 3D-specific radioprotective role of VEGF/Akt signaling through functional activation of NHEJ Gomez-Roman Natividad, Chong Ming Y, Chahal Sandeep K, Caragher Seamus P, Jackson Mark R, Stevenson Katrina H, Dongre Sidhartha A, Chalmers Anthony J Molecular Cancer Therapeutics Vol 19, pp. 575-589 (2020) https://doi.org/10.1158/1535-7163.MCT-18-1320
Publications
Back to staff profile
F1000Research (Journal) Peer reviewer 11/8/2023 Co-chair Radiotherapy drug combinations Speaker 4/6/2023 RadNet Glasgow Brainstorming Workshop Participant 2/6/2023 Scottish Glioblastoma Network - Brain Tumour Scottish Network (External organisation) Member 6/2023 SIPBS Research Day 2023 Chair 1/6/2023 Deciphering the role of cholesterol in the radiation response of glioblastoma Speaker 13/5/2023
BRAINS Strathclyde Centre for Doctoral Training MacKenzie, Lewis (Principal Investigator) Childs, Peter (Principal Investigator) Witte, Kimia (Principal Investigator) Jimenez, Melanie (Principal Investigator) Chow, Shiao (Principal Investigator) Fu, Ying (Principal Investigator) Gomez-Roman, Natividad (Principal Investigator) Fazio, Mariana (Principal Investigator) Reid, Andrew Baxter (Principal Investigator) Centre for Doctoral Training in Bridging Research and Advancements in Neurological Sciences (BRAINS). First cohort of PhD students starting autumn 2023. 01-Jan-2023 Developing Aberdeen's Cancer Research Network Spiers, Valerie (Principal Investigator) kiltie, anne (Principal Investigator) Gomez-Roman, Natividad (Co-investigator) Boyd, Marie (Co-investigator) Tomlinson, Ian P M (Principal Investigator) Gourley, Charlie (Co-investigator) Machesky, Laura (Co-investigator) Chalmers, Anthony (Principal Investigator) Broche, Lionel (Co-investigator) Stansfield, Ian (Co-investigator) The aim of this proposal is to encourage new collaborative research and innovation in these fields, through working with colleagues in the CRUK Scotland Centre based in Edinburgh and Glasgow, broadening the range of cancer research being conducted in Scotland. 01-Jan-2022 - 30-Jan-2023 Investigating Novel Wee1 and Chk1 Inhibitors with Improved Brain Permeability for the Treatment of Glioblastoma Gomez-Roman, Natividad (Principal Investigator) SULSA-industrial collaboration evaluating novel brain permeable compounds in 3D glioblastoma model systems 01-Jan-2022 - 31-Jan-2023 Understanding the role of cholesterol in the survival and treatment resistance of glioblastoma and its feasibility as a druggable target Gomez-Roman, Natividad (Principal Investigator) Morgan, John (Post Grad Student) 01-Jan-2021 - 30-Jan-2024 Developing more representative laboratory models of the blood-tumour barrier to improve the drug development pipeline for patients with glioblastoma. Chalmers, Anthony (Principal Investigator) Carruthers, Ross D (Co-investigator) Birch, Joanna (Co-investigator) Smith, Colin (Co-investigator) Ireson, Chistopher (Co-investigator) Brennan, Paul (Co-investigator) Thompson, Gerry (Co-investigator) Gomez-Roman, Natividad (CoI) Salmeron-Sanchez, Manuel (CoI) Brunton, Val (CoI) 01-Jan-2021 - 31-Jan-2024 Investigating cholesterol protection to radiation treatment in glioblastoma Gomez-Roman, Natividad (Principal Investigator) 01-Jan-2021 - 31-Jan-2023
Professional Activities
Projects
Back to staff profile
Contact
Dr
Natividad
Gomez-Roman
Strathclyde Chancellor's Fellow
Strathclyde Institute of Pharmacy and Biomedical Sciences
Email: natividad.gomez-roman@strath.ac.uk
Tel: 548 2122