Dr Natividad Gomez-Roman

Senior Lecturer

Strathclyde Institute of Pharmacy and Biomedical Sciences

Personal statement

Our work aims to understand the tumour biology of brain and ovarian cancers, which will help us identify novel treatments resulting in improved patient outcomes. We pursue this by developing experimental models of disease that recapitulate the clinical environment, including three-dimensional cell culture systems using scaffolds, organoid and ex-vivo models and in vivo models of disease.

Expertise

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Prize And Awards

2023 AWERB 3Rs Prize: Recipient; 4/10/2023
Fellowship of the Higher Education Academy: Recipient; 7/9/2023
CRUK RadNet CRISPR Workshop Travel Bursary: Recipient; 14/6/2022
Strathclyde Chancellor's Fellowship: Recipient; 1/11/2020
Poster Prize, NC3Rs Fellows Meeting: Recipient; 1/5/2019
Aurora Programme for Professional Development in Women: Recipient; 1/9/2018

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Publications

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Publications

Human iPSC-derived cerebral organoids as a translational model for stroke and preclinical therapeutic screening: Omerigwe Simon Achi, Gomez-Roman Natividad, Newton Kathryn, Bowles Kathryn R, Carswell Hilary; SIPBS Postgraduate Research Day 2025 (2025)
P12.58.a - Role of Il-33/ST2 axis in glioblastoma development and its response to treatment: Zhao F, Rominiyi O, Collis S, Jiang H, Gomez-Roman N; Neuro-Oncology Vol 27, pp. iii130-iii130 (2025); https://doi.org/10.1093/neuonc/noaf193.437
P01.47.a - Impact of cholesterol synthesis inhibition in G7 glioblastoma stem-like cells cultured as 3D spheroids: Mirza S, Gomez-Roman N; Neuro-Oncology Vol 27, pp. iii41-iii41 (2025); https://doi.org/10.1093/neuonc/noaf193.127
Human iPSC-Derived Cerebral Organoids for In Vitro Stroke Modelling and Therapeutic Testing: Omerigwe Simon Achi, Gomez-Roman Natividad, Newton Kathryn, Bowles Kathryn R, Carswell Hilary; 7th UK Preclinical Stroke Symposium, pp. 45-46 (2025)
Ex-vivo models of post-surgical residual disease in human glioblastoma: Rominiyi Ola, McGarrity-Cottrell Connor, Myers Katie, Jones Callum, Wosnitzka Kelsey, Williams Sophie T, Vanderlinden Aurelie, Antohj Andra-Gabriela, Gomez-Roman Natividad, Chalmers Anthony J, Sinha Saurab, Carrol Thomas A, Wang Dennis, Cavalli Andrea, Bagga Veejay, Al-Tamimi Yahia, Dunning Mark J, Collis Spencer J; F1000Research Vol 13 (2024); https://doi.org/10.12688/f1000research.157013.1
P13.06. A evaluation of BBB permeable WEE1 and CHK1 inhibitors in combination with standard of care for the treatment of Glioblastoma: Scholefield E L, Gomez-Roman N; Neuro-Oncology Vol 26, pp. v72-v72 (2024); https://doi.org/10.1093/neuonc/noae144.239

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Research

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Professional Activities

Dutch Research Council, Round Open Competition Domain Science Package 25-4 (Event): Peer reviewer; 8/4/2026
Brain Research UK (External organisation): Advisor; 25/3/2026
Targeting Cholesterol Pathways to Modulate Radiation Response in Glioblastoma (External Organisation): Speaker; 12/1/2026
External Examiner, PhD Student (External Organisation): Examiner; 19/11/2025
External Examiner for MPhil student (External Organisation): Examiner; 22/10/2025
Institute for Regeneration and Repair, University of Edingburgh (External organisation): Advisor; 1/10/2025

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Projects

Targeting IKK-alpha to Improve Glioblastoma Treatment Response: Gomez-Roman, Natividad (Principal Investigator) Crawford, Chloe (Researcher); Investigation into the treatment combination of IKKalpha inhibition in combination with radiation in GBM; 01-Jan-2026 - 10-Jan-2026
Cancer-Targeting Upconversion Nanoparticles to Track-and-Treat Glioblastoma: MacKenzie, Lewis (Principal Investigator) Chow, Shiao (Co-investigator) Gomez-Roman, Natividad (Co-investigator); 01-Jan-2025 - 31-Jan-2027
Revio Therapeutics - Contract: Gomez-Roman, Natividad (Principal Investigator); 01-Jan-2025 - 31-Jan-2026
Revio Therapeutics - Research Contract: Gomez-Roman, Natividad (Principal Investigator); Investigation into treatment combination with radiation using 3D-scaffold glioblastoma model; 01-Jan-2025 - 31-Jan-2026
Investigating the role of obesity and fatty acids in promoting GBM survival: Gammoh, Noor (Principal Investigator) Gomez-Roman, Natividad (Co-investigator) Banerjee, Sourav (Co-investigator); CRUK Scotland Centre - Edinburgh Cancer Research Funded Studentships; 01-Jan-2025 - 30-Jan-2029
Investigating neurotransmitter-mediated tumour microenvironment in glioblastoma: Li, Jianbin (Post Grad Student) Gomez-Roman, Natividad (Principal Investigator); 01-Jan-2024 - 30-Jan-2027