Publications

Incorporating immunostimulatory lipids into lipid nanoparticles : exploring expression and immune responses

Evdokimou Maria, Alaqabani Hakam, Hussain Muattaz, Perrie Yvonne

European Journal of Pharmaceutics and Biopharmaceutics Vol 223 (2026)

https://doi.org/10.1016/j.ejpb.2026.115034

Camptothecin-bearing PEGylated polypropylenimine dendriplexes for prostate cancer gene therapy : impact of microfluidic processing on physicochemical properties and transfection

Al-Quraishi Zainab, Ali-Jerman Hawraa, Laskar Partha, Muglikar Ashish, Mackie Logan, Mullin Margaret, Mackenzie Graeme, Tate Rothwelle J, Hussain Muattaz, Perrie Yvonne, Dufès Christine

Pharmaceutics Vol 18 (2026)

https://doi.org/10.3390/pharmaceutics18020190

The use of enhanced analytical pipelines for the characterisation of Poly(A) and Poly(A)-LNP formulation critical quality attributes

Davidson Callum G, Kapsali Eleni, Ioannou Savvas, Kopilovic Bojan, Hussain Muattaz, Perrie Yvonne, Rattray Zahra

Molecular Pharmaceutics Vol 22, pp. 7383-7399 (2025)

https://doi.org/10.1021/acs.molpharmaceut.5c00614

Redefining LNP composition : phospholipid and sterol-driven modulation of mRNA expression and immune outcomes

Hussain Muattaz, Muglikar Ashish, Brain Danielle E, Plant-Hately Alexander J, Liptrott Neill J, McLoughlin Daragh M, Perrie Yvonne

RSC Pharmaceutics Vol 2, pp. 1458-1470 (2025)

https://doi.org/10.1039/d5pm00150a

Mind the age gap : expanding the age window for mRNA vaccine testing in mice

Hussain Muattaz, Ferguson-Ugorenko Agata, Macfarlane Rebecca, Orr Natalie, Clarke Samuel, Wilkinson Michael JA, Horan Linda, Perrie Yvonne

Vaccines Vol 13 (2025)

https://doi.org/10.3390/vaccines13040370

Exploring the challenges of lipid nanoparticle development : the in vitro–in vivo correlation gap

Lindsay Sarah, Hussain Muattaz, Binici Burcu, Perrie Yvonne

Vaccines Vol 13 (2025)

https://doi.org/10.3390/vaccines13040339

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