Dr Hui-Rong Jiang

Reader

Strathclyde Institute of Pharmacy and Biomedical Sciences

Personal statement

I received my first degree in Medicine from China Medical University and completed PhD in Immunology/Ophthalmology at Aberdeen University in 2001. Between 2001 and 2009 I was a postdoctoral researcher and then a senior research fellow at the universities of Cambridge, Manchester (Paterson Institute for Cancer Research) and Glasgow. I joined the University of Strathclyde in 2010.

Research in my group focuses on understanding how immune cells and molecules are organised in vivo within a regulatory network during the development of autoimmune and neurological disorders, with a particular interest in multiple sclerosis and Alzheimer’s disease, and thus find those potential molecules which may be the best targets for clinical intervention.

Expertise

Has expertise in:

    • Autoimmunity and autoimmune disease
    • Neuroimmunology
    • In vivo immunobiology
    • Cancer immunology

Publications

Quantification of the influence of drugs on zebrafish larvae swimming kinematics and energetics
Zhao Zhenkai, Li Gen, Xiao Qing, Jiang Hui-Rong, Tchivelekete Gabriel Mbuta, Shu Xinhua, Liu Hao
PeerJ Vol 8 (2020)
https://doi.org/10.7717/peerj.8374
Interleukin-16 inhibits sodium channel function and GluA1 phosphorylation via CD4- and CD9-independent mechanisms to reduce hippocampal neuronal excitability and synaptic activity
Hridi Shehla U, Franssen Aimée JPM, Jiang Hui-Rong, Bushell Trevor J
Molecular and Cellular Neuroscience Vol 95, pp. 71-78 (2019)
https://doi.org/10.1016/j.mcn.2019.01.002
Expression and function of IL-33/ST2 axis in the central nervous system under normal and diseased conditions
Fairlie-Clarke Karen, Barbour Mark, Wilson Chelsey, Hridi Shehla U, Allan Debbie, Jiang Hui-Rong
Frontiers in Immunology Vol 9 (2018)
https://doi.org/10.3389/fimmu.2018.02596
Failure of the anti-inflammatory parasitic worm product ES-62 to provide protection in mouse models of type I diabetes, multiple sclerosis, and inflammatory bowel disease
Doonan James, Thomas David, Wong Michelle H, Ramage Hazel J, Al-Riyami Lamyaa, Lumb Felicity E, Bell Kara S, Fairlie-Clarke Karen J, Suckling Colin J, Michelsen Kathrin S, Jiang Hui-Rong, Cooke Anne, Harnett Margaret M, Harnett William
Molecules Vol 23 (2018)
https://doi.org/10.3390/molecules23102669
The therapeutic effect of anti-CD52 treatment in murine experimental autoimmune encephalomyelitis is associated with altered IL-33 and ST2 expression levels
Barbour Mark, Wood Rachel, Hridi Shehla U, Wilson Chelsey, McKay Grant, Bushell Trevor J, Jiang Hui-Rong
Journal of Neuroimmunology, pp. 1-33 (2018)
https://doi.org/10.1016/j.jneuroim.2018.02.012
Expression of IL-22 and IL-22R1 subunit in the central nervous system of experimental autoimmune encephalomyelitis mice
Wilson Chelsey, Bushell Trevor, Jiang Hui-Rong
BSI Edinburgh Immunology Conference. Edinburgh, UK (2017)

More publications

Teaching

I coordinate the following courses: Clinical Immunology BM426; Advanced techniques in in vivo biology BM437; PG Advanced techniques in in vivo biology MP968; PG Advanced topics in immunology BM945.

I lecture on the following courses: Immunology labs BM214 and BM327;  Clinical Immunology BM426; 4th year biomedical research project supervision BM432; Advanced techniques in in vivo biology BM437 and MP968; PG Advanced topics in immunolog BM945; Targeted cancer therapies for personalised medicine MP981; Advanced Techniques in Biomedical Research MP959. 

I supervise MRes, MSc and MSci research projects.

From 2010 to 2017, I organized the annual British Pharmacological Society funded Immunology Summer School for undergraduates and graduates from various UK institutions. Currently I am a member of Education Expert group on Research Animal Sciences Education Scheme, organised by the Physiological Society and the British Pharmacological Society.

Projects

Developing therapies for Alzheimer's disease
Jiang, Hui-Rong (Principal Investigator) Sakata, Shuzo (Co-investigator)
01-Jan-2020 - 31-Jan-2021
Understanding the action mechanisms of gamma oscillation for AD disease
Jiang, Hui-Rong (Principal Investigator) Sakata, Shuzo (Principal Investigator)
01-Jan-2020 - 30-Jan-2021
Immunomechanisms of gamma oscillation treatment for Alzheimer's disease
Jiang, Hui-Rong (Principal Investigator) Sakata, Shuzo (Co-investigator) Harte, Tanith (Post Grad Student)
The study aims to identify the specific immune cells and molecules which mediate the action of induced gamma oscillation, a potential novel treatment for AD patients.
01-Jan-2019 - 30-Jan-2022
Biomedical Vacation Scholarships
Coats, Paul (Principal Investigator) Jiang, Hui-Rong (Principal Investigator) Lawrence, Catherine (Principal Investigator) McDonald, James (Principal Investigator) Pickard, Ben (Principal Investigator)
09-Jan-2018 - 31-Jan-2018
Biomedical Vacation Scholarships / R180191-3
Jiang, Hui-Rong (Principal Investigator)
09-Jan-2018 - 31-Jan-2018
The Biochemical Society Summer Vacation Studentship: Project ‘The role of PAR4 in EAE models of Multiple Sclerosis’
Wood, Rachel Aimee (Principal Investigator) Barbour, Mark (Principal Investigator) McEwan, Ryan (Researcher) Cunningham, Margaret Rose (Academic) Jiang, Hui-Rong (Academic)
PI: Dr Rachel Wood, Co-applicants: Dr Mark Barbour, Dr Margaret Cunningham and Dr Hui-Rong Jiang £1600, 2018
Student: Mr Ryan McEwan
01-Jan-2018 - 31-Jan-2018

More projects

Address

Strathclyde Institute of Pharmacy and Biomedical Sciences
Hamnett Wing

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