Dr Hui-Rong Jiang

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Strathclyde Institute of Pharmacy and Biomedical Sciences

Personal statement

I received my first degree in Medicine from China Medical University and completed PhD in Immunology/Ophthalmology with Professor John V Forrester at Aberdeen University in 2001. I then joined research teams at the universities of Cambridge (Professor Jenefer Blackwell), Manchester (Paterson Institute for Cancer Research, Professor Peter Stern) and Glasgow (Professor Eddy Liew). In 2010 I joined the University of Strathclyde.

Research in my group focuses on understanding how immune cells and molecules are organised in vivo within a regulatory network during the development of autoimmune and neurological disorders, with a particular interest in multiple sclerosis and Alzheimer’s disease, and thus find those potential molecules which may be the best targets for clinical intervention.

Publications

Anti-CD52 antibody treatment in murine experimental autoimmune encephalomyelitis induces dynamic and differential modulation of innate immune cells in peripheral immune and central nervous systems: Barbour Mark, Wood Rachel, Harte Tanith, Bushell Trevor J, Jiang Hui-Rong; Immunology Vol 165, pp. 312-327 (2022); https://doi.org/10.1111/imm.13437
Protease-activated receptor 2 activation induces behavioural changes associated with depression-like behaviour through microglial-independent modulation of inflammatory cytokines: Moudio Serge, Willis Ashleigh, Pytka Karolina, Abulkassim Roua, Brett Ros R, Webster Jack F, Wozny Christian, Barbour Mark, Jiang Hui-Rong, Watson David G, van Kralingen Josie C, Mackenzie Scott M, Daniels Michael, McColl Barry W, Sossick Sandra, Nuthall Hugh N, Bushell Trevor J; Psychopharmacology Vol 239, pp. 229-242 (2022); https://doi.org/10.1007/s00213-021-06040-1
Increased levels of IL-16 in the central nervous system during neuroinflammation are associated with infiltrating immune cells and resident glial cells: Hridi Shehla U, Barbour Mark, Wilson Chelsey, Franssen Aimee JPM, Harte Tanith, Bushell Trevor J, Jiang Hui-Rong; Biology Vol 10 (2021); https://doi.org/10.3390/biology10060472
Quantification of computational fluid dynamics simulation assists the evaluation of protection by Gypenosides in a zebrafish pain model: Zhao Zhenkai, Xiao Qing, Tchivelekete Gabriel Mbuta, Reilly James, Jiang Huirong, Shu Xinhua; Physiology and Behavior Vol 229 (2021); https://doi.org/10.1016/j.physbeh.2020.113223
Quantification of the influence of drugs on zebrafish larvae swimming kinematics and energetics: Zhao Zhenkai, Li Gen, Xiao Qing, Jiang Hui-Rong, Tchivelekete Gabriel Mbuta, Shu Xinhua, Liu Hao; PeerJ Vol 8 (2020); https://doi.org/10.7717/peerj.8374
Interleukin-16 inhibits sodium channel function and GluA1 phosphorylation via CD4- and CD9-independent mechanisms to reduce hippocampal neuronal excitability and synaptic activity: Hridi Shehla U, Franssen Aimée JPM, Jiang Hui-Rong, Bushell Trevor J; Molecular and Cellular Neuroscience Vol 95, pp. 71-78 (2019); https://doi.org/10.1016/j.mcn.2019.01.002

More publications

Teaching

I coordinate Clinical Immunology BM426; Advanced techniques in in vivo biology BM437; PG Advanced techniques in in vivo biology MP968; PG Advanced topics in immunology BM945.

I lecture on the following modules: Immunology labs BM214 and BM327; Clinical Immunology BM426; 4th year biomedical research project BM432; Advanced techniques in in vivo biology BM437 and MP968; PG Advanced topics in immunolog BM945; Targeted cancer therapies for personalised medicine MP981; Advanced Techniques in Biomedical Research MP959; MSc Neuroscience modules and MPharm module Management of inflammation conditions.

I supervise MSc and MSci research projects.

From 2010 to 2017, organiser of the annual British Pharmacological Society funded Immunology Summer School for undergraduates and graduates from various UK institutions. Currently I am a member of Education Expert group on Research Animal Sciences Education Scheme, organised by the Physiological Society and the British Pharmacological Society.

2014 - 2021, Deputy Academic Selector of BMS.

2021 - present, BMS 4th year coordinator.

Projects

RS Macdonald - Lysozyme encapsulated gold nanoclusters – a new therapeutic agent for Alzheimer’s disease: Jiang, Hui-Rong (Principal Investigator); 01-Jan-2023 - 30-Jan-2025
Lysozyme encapsulated gold nanoclusters – a new therapeutic agent for Alzheimer’s disease: Jiang, Hui-Rong (Principal Investigator) Chen, Yu (Co-investigator) Sakata, Shuzo (Co-investigator); 01-Jan-2022 - 30-Jan-2025
ARUK Scotland Network Centre grants: Jiang, Hui-Rong (Principal Investigator); 01-Jan-2022 - 31-Jan-2023
Developing therapies for Alzheimer's disease: Jiang, Hui-Rong (Principal Investigator) Sakata, Shuzo (Co-investigator); 01-Jan-2020 - 31-Jan-2023
Understanding the action mechanisms of gamma oscillation for AD disease: Jiang, Hui-Rong (Principal Investigator) Sakata, Shuzo (Principal Investigator); 01-Jan-2020 - 30-Jan-2021
Immunomechanisms of gamma oscillation treatment for Alzheimer's disease: Jiang, Hui-Rong (Principal Investigator) Sakata, Shuzo (Co-investigator) Harte, Tanith (Post Grad Student); The study aims to identify the specific immune cells and molecules which mediate the action of induced gamma oscillation, a potential novel treatment for AD patients.; 01-Jan-2019 - 30-Jan-2022

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Address

Strathclyde Institute of Pharmacy and Biomedical Sciences
Hamnett Wing

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