Professor Blair Johnston

Strathclyde Institute of Pharmacy and Biomedical Sciences

Publications

A novel integrated workflow for isolation solvent selection using prediction and modelling
Ottoboni Sara, Wareham Bruce, Vassileiou Antony, Robertson Murray, Brown Cameron J, Johnston Blair, Price Chris J
Organic Process Research and Development Vol 25, pp. 1143-1159 (2021)
https://doi.org/10.1021/acs.oprd.0c00532
Quantification of swelling characteristics of pharmaceutical particles
Soundaranathan Mithushan, Vivattanaseth Pattavet, Walsh Erin, Pitt Kendal, Johnston Blair, Markl Daniel
International Journal of Pharmaceutics Vol 590 (2020)
https://doi.org/10.1016/j.ijpharm.2020.119903
Olanzapine crystal symmetry originates in preformed centrosymmetric solute dimers
Warzecha Monika, Verma Lakshmanji, Johnston Blair F, Palmer Jeremy C, Florence Alastair J, Vekilov Peter G
Nature Chemistry Vol 12, pp. 914-920 (2020)
https://doi.org/10.1038/s41557-020-0542-0
Data mining crystallization kinetics
Brown Cameron, Maldonado Diego A, Vassileiou Antony, Johnston Blair, Florence Alastair
Current Trends in Chemical Process Technology and Materials Development (2020)
Data mining crystallization kinetics
Brown Cameron, Maldonado Diego, Vassileiou Antony, Johnston Blair, Florence Alastair
(2020)
Non-leaching, highly biocompatible nanocellulose surfaces that efficiently resist fouling by bacteria in an artificial dermis model
Hassan Ghada, Forsman Nina, Wan Xing, Keurulainen Leena, Bimbo Luis M, Stehl Susanne, van Charante Frits, Chrubasik Michael, Prakash Aruna S, Johansson Leena-Sisko, Mullen Declan C, Johnston Blair F, Zimmermann Ralf, Werner Carsten, Yli-Kauhaluoma Jari, Coenye Tom, Saris Per E J, Österberg Monika, Moreira Vânia M
ACS Applied Bio Materials Vol 3, pp. 4095-4108 (2020)
https://doi.org/10.1021/acsabm.0c00203

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Research interests

Dr Blair Johnston is a Reader in Computational Modelling at the Strathclyde Institute of Pharmacy and Biomedical Sciences. He teaches on the Masters of Pharmacy, Pharmaceutical Analysis, Clinical Pharmacy and Chemistry with Drug Discovery degrees.

My group has research interests in five broad areas: drug discovery, molecular structure simulation, machine learning and prediction, data analysis, and web-enabled science and collaboration tools. In the vast majority of our research, we work closely with experimental scientists in the design and execution of collaborative research to realise the full potential of their laboratory data. This combination of experiment and theory often provides unique insight into the systems being studied.

Professional activities

Novel off-target effects of doxorubicin on cardiovascular gap-junctional proteins
Contributor
5/2/2021
P011 - Endothelial connexin-43 dysregulation in response to the anthracycline doxorubicin
Contributor
14/12/2020
P2.5.6 - Novel off-target effects of anti-cancer drugs on cardiovascular gap-junctional proteins
Contributor
12/10/2020
Data Mining Crystallisation Kinetics
Contributor
19/8/2020
Cambridge Crystallographic Data Centre (CCDC) European UGM and Science Day
Participant
13/6/2019
EPSRC Future Manufacturing Research Hubs Showcase Event - CMAC
Speaker
30/4/2019

More professional activities

Projects

Made Smarter Innovation: Digital Medicines Manufacturing Research Centre (DM2)
Florence, Alastair (Principal Investigator) Johnston, Blair (Co-investigator) Markl, Daniel (Co-investigator) Pierce, Gareth (Co-investigator)
01-Jan-2021 - 28-Jan-2025
Digital Design Accelerator Platform to Connect Active Material Design to Product Performance (Manufacturing Made Smarter)
Florence, Alastair (Principal Investigator) Johnston, Blair (Co-investigator)
01-Jan-2020 - 28-Jan-2022
Doctoral Training Partnership 2018-19 University of Strathclyde | Pereira-Diaz, Laura
Florence, Alastair (Principal Investigator) Brown, Cameron (Co-investigator) Johnston, Blair (Co-investigator) Pereira-Diaz, Laura (Research Co-investigator)
01-Jan-2019 - 01-Jan-2023
Investigating the biomolecular complexity of drug-induced cardiotoxicity by fingerprinting single cell and cardiac spheroid mass spectral information using Time-of-flight Secondary Ion Mass Spectrometry (TOF-SIMS)
Cunningham, Margaret Rose (Principal Investigator) Veerman, Ben (Post Grad Student) Johnston, Blair (Co-investigator) Currie, Susan (Co-investigator)
The aim of this project is to significantly advance upon ongoing efforts in understanding drug-induced cardiotoxicity not only at the single cell level but in a multicellular model that may better reflect the cellular microenvironment of the heart. Extending studies to assess the metabolite changes in the multicellular environment in response to cancer therapeutics may reveal events integral to toxicity which may lead to new knowledge to develop ways to minimise or prevent cellular toxicity in the cardiac niche.
01-Jan-2019 - 28-Jan-2022
Accelerated Discovery and Development of New Medicines: Prosperity Partnership for a Healthier Nation
Kerr, William (Principal Investigator) Brown, Cameron (Co-investigator) Florence, Alastair (Co-investigator) Jamieson, Craig (Co-investigator) Johnston, Blair (Co-investigator) Murphy, John (Co-investigator) Palmer, David (Co-investigator) Tomkinson, Nick (Co-investigator)
Accelerated Discovery and Development of New Medicines: Prosperity Partnership for a Healthier Nation
01-Jan-2019 - 31-Jan-2023
ARTICULAR: ARtificial inTelligence for Integrated ICT-enabled pharmaceUticaL mAnufactuRing
Johnston, Blair (Principal Investigator) Brown, Cameron (Co-investigator) Florence, Alastair (Co-investigator)
ARtificial inTelligence for Integrated ICT-enabled pharmaceUticaL mAnufactuRing
01-Jan-2018 - 30-Jan-2022

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Address

Strathclyde Institute of Pharmacy and Biomedical Sciences
Technology Innovation Centre

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