Publications

Optimisation of additively manufactured coiled flow inverters for continuous viral inactivation processes

Barrera Maria Cecilia, Leech Damien, Josifovic Aleksandar, Tolouei Anita, Alford Gareth, Wallace Martin J, Bennett Nicholas, Wildman Ricky, Irvine Derek J, Croft Anna, Özcan Ender, Florence Alastair J, Johnston Blair, Robertson John, Brown Cameron J

Chemical Engineering Research and Design Vol 213, pp. 126-136 (2025)

https://doi.org/10.1016/j.cherd.2024.11.040

Flexible modelling of the dissolution performance of directly compressed tablets

Maclean Natalie, Armstrong John A, Carroll Mark A, Salehian Mohammad, Mann James, Reynolds Gavin, Johnston Blair, Markl Daniel

International Journal of Pharmaceutics Vol 656 (2024)

https://doi.org/10.1016/j.ijpharm.2024.124084

Digital process design to define and deliver pharmaceutical particle attributes

Urwin Stephanie J, Chong Magdalene WS, Li Wei, McGinty John, Mehta Bhavik, Ottoboni Sara, Pathan Momina, Prasad Elke, Robertson Murray, McGowan Mark, al-Attili Mais, Gramadnikova Ekaterina, Siddique Mariam, Houson Ian, Feilden Helen, Benyahia Brahim, Brown Cameron J, Halbert Gavin W, Johnston Blair, Nordon Alison, Price Chris J, Reilly Chris D, Sefcik Jan, Florence Alastair J

Chemical Engineering Research and Design Vol 196, pp. 726-749 (2023)

https://doi.org/10.1016/j.cherd.2023.07.003

A unified ML framework for solubility prediction across organic solvents

Vassileiou Antony D, Robertson Murray N, Wareham Bruce G, Soundaranathan Mithushan, Ottoboni Sara, Florence Alastair J, Hartwig Thoralf, Johnston Blair F

Digital Discovery Vol 2, pp. 356-367 (2023)

https://doi.org/10.1039/D2DD00024E

Modelling the evolution of pore structure during the disintegration of pharmaceutical tablets

Soundaranathan Mithushan, Al-Sharabi Mohammed, Sweijen Thomas, Bawuah Prince, Zeitler J Axel, Hassanizadeh S Majid, Pitt Kendal, Johnston Blair F, Markl Daniel

Pharmaceutics Vol 15 (2023)

https://doi.org/10.3390/pharmaceutics15020489

Application of a structured approach to implementation of measurements to a 5-stage cooling crystallisation process

Chong Magdalene, Li Wei, Brown Cameron, McGinty John, Robertson Murray, Johnston Blair, Sefcik Jan, Benyahia Brahim, Rielly Chris, Nordon Alison

Advances in Process Analytics and Control Technologies (2022)

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Research Interests

Dr Blair Johnston is a Reader in Computational Modelling at the Strathclyde Institute of Pharmacy and Biomedical Sciences. He teaches on the Masters of Pharmacy, Pharmaceutical Analysis, Clinical Pharmacy and Chemistry with Drug Discovery degrees.

My group has research interests in five broad areas: drug discovery, molecular structure simulation, machine learning and prediction, data analysis, and web-enabled science and collaboration tools. In the vast majority of our research, we work closely with experimental scientists in the design and execution of collaborative research to realise the full potential of their laboratory data. This combination of experiment and theory often provides unique insight into the systems being studied.

Professional Activities

Data Mining Crystallisation Kinetics

Contributor

31/3/2021

Novel off-target effects of doxorubicin on cardiovascular gap-junctional proteins

Contributor

5/2/2021

P011 - Endothelial connexin-43 dysregulation in response to the anthracycline doxorubicin

Contributor

14/12/2020

P2.5.6 - Novel off-target effects of anti-cancer drugs on cardiovascular gap-junctional proteins

Contributor

12/10/2020

Data Mining Crystallisation Kinetics

Contributor

19/8/2020

Cambridge Crystallographic Data Centre (CCDC) European UGM and Science Day

Participant

13/6/2019

More professional activities

Projects

DPN-MED: Digital Plug-and-Produce Network for Sustainable Medicines Development and Manufacturing

Fitzpatrick, Stephen (Principal Investigator) Florence, Alastair (Principal Investigator) Florence, Alastair (Co-investigator) Johnston, Blair (Co-investigator) Markl, Daniel (Co-investigator)

01-Jan-2025 - 30-Jan-2025

PharmaCrystNet: Improving the Predictive Capabilities of Crystallisation Models in

Brown, Cameron (Principal Investigator) Dolean Maini, Victorita (Co-investigator) Johnston, Blair (Co-investigator)

01-Jan-2024 - 31-Jan-2025

SHARPEN: SHARing data to accelerate Pharmaceutical manufacturing Efficiency across trusted Networks

Johnston, Blair (Principal Investigator) Florence, Alastair (Co-investigator) Markl, Daniel (Co-investigator)

01-Jan-2024 - 31-Jan-2026

A Regulatory Science Network for the Digital Transformation of Medicines Development and Manufacturing (10113547)

Markl, Daniel (Principal Investigator) Florence, Alastair (Co-investigator) Johnston, Blair (Co-investigator)

01-Jan-2024 - 31-Jan-2024

DTP 2224 University of Strathclyde | Robertson, Jason

Johnston, Blair (Principal Investigator) Markl, Daniel (Co-investigator) Robertson, Jason (Research Co-investigator)

01-Jan-2023 - 01-Jan-2029

DTP 2224 University of Strathclyde | Clark, Connor

Florence, Alastair (Principal Investigator) Johnston, Blair (Co-investigator) Clark, Connor (Research Co-investigator)

01-Jan-2023 - 01-Jan-2027

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