Professor Blair Johnston

Strathclyde Institute of Pharmacy and Biomedical Sciences

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Publications

Flexible modelling of the dissolution performance of directly compressed tablets
Maclean Natalie, Armstrong John A, Carroll Mark A, Salehian Mohammad, Mann James, Reynolds Gavin, Johnston Blair, Markl Daniel
International Journal of Pharmaceutics Vol 656 (2024)
https://doi.org/10.1016/j.ijpharm.2024.124084
Digital process design to define and deliver pharmaceutical particle attributes
Urwin Stephanie J, Chong Magdalene WS, Li Wei, McGinty John, Mehta Bhavik, Ottoboni Sara, Pathan Momina, Prasad Elke, Robertson Murray, McGowan Mark, al-Attili Mais, Gramadnikova Ekaterina, Siddique Mariam, Houson Ian, Feilden Helen, Benyahia Brahim, Brown Cameron J, Halbert Gavin W, Johnston Blair, Nordon Alison, Price Chris J, Reilly Chris D, Sefcik Jan, Florence Alastair J
Chemical Engineering Research and Design Vol 196, pp. 726-749 (2023)
https://doi.org/10.1016/j.cherd.2023.07.003
A unified ML framework for solubility prediction across organic solvents
Vassileiou Antony D, Robertson Murray N, Wareham Bruce G, Soundaranathan Mithushan, Ottoboni Sara, Florence Alastair J, Hartwig Thoralf, Johnston Blair F
Digital Discovery Vol 2, pp. 356-367 (2023)
https://doi.org/10.1039/D2DD00024E
Modelling the evolution of pore structure during the disintegration of pharmaceutical tablets
Soundaranathan Mithushan, Al-Sharabi Mohammed, Sweijen Thomas, Bawuah Prince, Zeitler J Axel, Hassanizadeh S Majid, Pitt Kendal, Johnston Blair F, Markl Daniel
Pharmaceutics Vol 15 (2023)
https://doi.org/10.3390/pharmaceutics15020489
Application of a structured approach to implementation of measurements to a 5-stage cooling crystallisation process
Chong Magdalene, Li Wei, Brown Cameron, McGinty John, Robertson Murray, Johnston Blair, Sefcik Jan, Benyahia Brahim, Rielly Chris, Nordon Alison
Advances in Process Analytics and Control Technologies (2022)
Data mining crystallization kinetics
Maldonado Diego A, Vassileiou Antony, Johnston Blair, Florence Alastair J, Brown Cameron J
Digital Discovery Vol 1, pp. 621-635 (2022)
https://doi.org/10.1039/D2DD00033D

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Research Interests

Dr Blair Johnston is a Reader in Computational Modelling at the Strathclyde Institute of Pharmacy and Biomedical Sciences. He teaches on the Masters of Pharmacy, Pharmaceutical Analysis, Clinical Pharmacy and Chemistry with Drug Discovery degrees.

My group has research interests in five broad areas: drug discovery, molecular structure simulation, machine learning and prediction, data analysis, and web-enabled science and collaboration tools. In the vast majority of our research, we work closely with experimental scientists in the design and execution of collaborative research to realise the full potential of their laboratory data. This combination of experiment and theory often provides unique insight into the systems being studied.

Professional Activities

Data Mining Crystallisation Kinetics
Contributor
31/3/2021
Novel off-target effects of doxorubicin on cardiovascular gap-junctional proteins
Contributor
5/2/2021
P011 - Endothelial connexin-43 dysregulation in response to the anthracycline doxorubicin
Contributor
14/12/2020
P2.5.6 - Novel off-target effects of anti-cancer drugs on cardiovascular gap-junctional proteins
Contributor
12/10/2020
Data Mining Crystallisation Kinetics
Contributor
19/8/2020
Cambridge Crystallographic Data Centre (CCDC) European UGM and Science Day
Participant
13/6/2019

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Projects

DTP 2224 University of Strathclyde | Robertson, Jason
Johnston, Blair (Principal Investigator) Markl, Daniel (Co-investigator) Robertson, Jason (Research Co-investigator)
01-Jan-2023 - 01-Jan-2029
DTP 2224 University of Strathclyde | Clark, Connor
Florence, Alastair (Principal Investigator) Johnston, Blair (Co-investigator) Clark, Connor (Research Co-investigator)
01-Jan-2023 - 01-Jan-2027
Industrial CASE Account - University of Strathclyde 2022 | Osman, Amal
Johnston, Blair (Principal Investigator) Florence, Alastair (Co-investigator) Osman, Amal (Research Co-investigator)
01-Jan-2022 - 01-Jan-2026
Dialling up 3D Printing Performance for On Demand Manufacturing (Programme Grant)
Florence, Alastair (Principal Investigator) Johnston, Blair (Co-investigator)
01-Jan-2022 - 30-Jan-2027
DTP 2224 University of Strathclyde | Tsioutsios, Alexandros
Markl, Daniel (Principal Investigator) Johnston, Blair (Co-investigator) Tsioutsios, Alexandros (Research Co-investigator)
01-Jan-2022 - 01-Jan-2026
International Collaboration for Digital Design and Manufacture of Amorphous Pharmaceuticals
Florence, Alastair (Principal Investigator) Brown, Cameron (Co-investigator) Johnston, Blair (Co-investigator) Markl, Daniel (Co-investigator) Robertson, John (Co-investigator)
01-Jan-2022 - 31-Jan-2025

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Contact

Professor Blair Johnston
Strathclyde Institute of Pharmacy and Biomedical Sciences

Email: blair.johnston@strath.ac.uk
Tel: 548 5756