Publications

Intranasal brain targeting of poorly soluble & permeable drugs by designing an easily scalable nasal delivery platform

Das Debanjan, Lalatsa Katerina

Drug Delivery to the Lungs 2025 (2025)

Continuous microfluidic manufacture of nano-in-microparticles combining 3D-printed micromixers and spray drying

Kara Aytug, Ongoren Baris, Anaya Bryan J, Lalatsa Aikaterini, Serrano Dolores R

Pharmaceutical Research (2025)

Heparin-azithromycin microparticulate nasal gels block SARS-CoV-2 and bacterial respiratory infections

Anaya Bryan J, Osouli-Bostanabad Karim, Tirado Diego F, González-Burgos Elena, Lalatsa Aikaterini, Serrano Dolores R

Carbohydrate Polymer Technologies and Applications Vol 12 (2025)

https://doi.org/10.1016/j.carpta.2025.101031

Engineering heparin-azithromycin microparticulate nasal gels for the dual prophylaxis and therapy of COVID-19 and bacterial respiratory infections

Anaya Meza Bryan Javier, Osouli Bostanabad Karim, Tirado Diego F, Gonzalez-Burgos Elena, Lalatsa Katerina, Serrano Lopez Dolores Remedios

15th PBP World Meeting on Pharmaceutics, Biopharmaceutics and Pharmaceutical Technology (2025)

Molecular aggregation–driven behaviour of amphotericin B in drug-eluting contact lenses : PBP-WM_363

Ruiz Helga K, Anaya Meza Bryan Javier, Varghese Eldhoe, Luciano Francis C, Dea-Ayuela Maria Auxiliadora, Lalatsa Katerina, Serrano Lopez Dolores Remedios

15th World Meeting in Pharmaceutics, Biopharmaceutics and Pharmaceutical Technology (2025)

Exosome-based drug delivery : a next-generation platform for cancer, infection, neurological and immunological diseases, gene therapy and regenerative medicine

Serrano Dolores R, Juste Francisco, Anaya Bryan J, Ramirez Bianca I, Sánchez-Guirales Sergio A, Quispillo John M, Hernandez Ester M, Simon Jesus A, Trallero Jose M, Serrano Celia, Rawat Satyavati, Lalatsa Katerina

Pharmaceutics Vol 17 (2025)

https://doi.org/10.3390/pharmaceutics17101336

More publications

Professional Activities

PhD Examination - University College London (UCL School of Pharmacy)

Examiner

20/6/2025

MRC (External organisation)

Advisor

3/6/2025

Advanced Materials (Journal)

Peer reviewer

15/5/2025

PhD Examiner - Universidad Complutense Madrid

Examiner

7/3/2025

National Science Center (External organisation)

Advisor

28/11/2024

Fundamentals of Pharmaceutical Nanoscience 2nd Edition (Hardcover)ISBN:9783031594779, 3031594770Book Editor (Event)

Peer reviewer

24/9/2024

More professional activities

Projects

Qualified persons training programme 25-27 extension to 4589/3422 K230850-101

Lalatsa, Aikaterini (Principal Investigator) Young, David (Co-investigator)

01-Jan-2025 - 31-Jan-2027

Understanding biofilm formation on medical device surfaces

Serrano, Dolores R. (Principal Investigator) Lalatsa, Aikaterini (Co-investigator) Ramage, Gordon (Co-investigator)

Implantation of medical devices, such as orthopaedic implants, accounts for a significant proportion of hospital-acquired infections. These infections are notoriously difficult to treat because they are primarily caused by biofilms. There is limited knowledge about biofilm formation on implanted devices, and existing in vitro models can not accurately replicate the physiological microenvironment, leading to a shortage of animal-free models for testing antimicrobial and antibiofilm strategies. No previous attempts to mimic medical device-biofilm interfaces are described in the literature as most of them only model the bone structure or the biofilm microenvironment, but not the complex interface between the two. This project aims to develop an in vitro 3D-printed organ-on-a-chip model that mimics the physiological human bone microenvironment in terms of osseointegration and biofilm growth on the surface of orthopaedic medical devices after implantation. The acetabular component of a hip replacement will be used as a proof of concept model. Novel methods to understand how bacterial and fungal biofilms (S. aureus and C. albicans) are formed on the surface of implanted medical devices will be developed allowing the testing of the efficacy of different antimicrobials. Validation of the methodology using in vivo preclinical PJI models will be carried out. The implementation of these novel 3D in vitro methods in clinical settings could significantly improve the management of prosthetic joint infections (PJIs) guiding the rational selection of antimicrobial drugs.

01-Jan-2025 - 31-Jan-2027

Development of a oligonucleotide nanoparticle

Lalatsa, Aikaterini (Principal Investigator)

14-Jan-2024 - 21-Jan-2024

Stability of Monoclonal Anti-Bodies (MABs) - Capillary Zone Electrophoresis analysis

Lalatsa, Aikaterini (Principal Investigator)

25-Jan-2024 - 19-Jan-2025

Manufacture and release of Lucentis Drug Product

Lalatsa, Aikaterini (Principal Investigator)

02-Jan-2023 - 28-Jan-2025

Engineered silks for surgical wounds

Lalatsa, Aikaterini (Principal Investigator) Connolly, Patricia (Co-investigator)

02-Jan-2023 - 30-Jan-2027

More projects