Professor Simon MacKay
Strathclyde Institute of Pharmacy and Biomedical Sciences
Back to staff profile
Publications
- IL-1β stimulates a novel, IKKα -dependent, NIK -independent activation of non-canonical NFκB signalling
- McIntosh Kathryn, Khalaf Yousif H, Craig Rachel, West Christopher, McCulloch Ashley, Waghmare Ajay, Lawson Christopher, Chan Edmond YW, MacKay Simon, Paul Andrew, Plevin Robin
- Cellular Signalling Vol 107 (2023)
- https://doi.org/10.1016/j.cellsig.2023.110684
- JAK–STAT signalling shapes the NF‐κB response in CLL towards venetoclax sensitivity or resistance via Bcl‐XL
- Haselager Marco V, Thijssen Rachel, Bax Danique, Both Demi, De Boer Francien, Mackay Simon, Dubois Julie, Mellink Clemens, Kater Arnon P, Eldering Eric
- Molecular Oncology Vol 17, pp. 1112-1128 (2023)
- https://doi.org/10.1002/1878-0261.13364
- Targeting the non-canonical NF-κB pathway in chronic lymphocytic leukemia and multiple myeloma
- Burley Thomas A, Kennedy Emma, Broad Georgia, Boyd Melanie, Li David, Woo Timothy, West Christopher, Ladikou Eleni E, Ashworth Iona, Fegan Christopher, Johnston Rosalynd, Mitchell Simon, Mackay Simon P, Pepper Andrea G S, Pepper Chris
- Cancers Vol 14 (2022)
- https://doi.org/10.3390/cancers14061489
- Mitokyne : a ratiometric raman probe for mitochondrial pH
- Wilson Liam T, Tipping William J, Wetherill Corinna, Henley Zoë, Faulds Karen, Graham Duncan, Mackay Simon P, Tomkinson Nicholas C O
- Analytical Chemistry Vol 93, pp. 12786-12792 (2021)
- https://doi.org/10.1021/acs.analchem.1c03075
- O47 : IKK-alpha as a potential novel target for treatment of colorectal cancer
- Patel M, Quinn JA, Pennel KAF, Flanagan D, Horgan PG, McMillan DC, MacKay S, Sansom O, Edwards J
- British Journal of Surgery Vol 108 (2021)
- https://doi.org/10.1093/bjs/znab117.047
- Regulation of Bcl-XL by non-canonical NF-κB in the context of CD40-induced drug resistance in CLL
- Haselager Marco, Thijssen Rachel, West Christopher, Young Louise, Van Kampen Roel, Willmore Elaine, Mackay Simon, Kater Arnon, Eldering Eric
- Cell Death and Differentiation Vol 28, pp. 1658-1668 (2021)
- https://doi.org/10.1038/s41418-020-00692-w
Back to staff profile
Professional Activities
- Prostate Cancer UK (External organisation)
- Member
- 1/10/2015
- REF (External organisation)
- Member
- 1/1/2014
- Japanese Society for the Promotion of Science
- Invited speaker
- 6/9/2013
- Academy of Pharmaceutical Sciences
- Invited speaker
- 3/9/2013
- Academy of Pharmaceutical Sciences
- Chair
- 3/9/2013
- Finland Academy of Science (External organisation)
- Member
- 29/1/2013
Projects
- TargoPep: a cell selective delivery platform for therapeutic payloads (Follow on Fund)
- Burley, Glenn (Principal Investigator) MacKay, Simon (Co-investigator) Perrie, Yvonne (Co-investigator) McWhinnie, Fergus (Research Co-investigator)
- 01-Jan-2023 - 31-Jan-2024
- Development of a first-in-class IKKalpha inhibitor for the treatment of castrate resistant p
- MacKay, Simon (Principal Investigator) Halbert, Gavin (Co-investigator) Paul, Andrew (Co-investigator) Suckling, Colin (Co-investigator) Watson, David (Co-investigator)
- 01-Jan-2020 - 31-Jan-2024
- CRUK evaluation of IKK inhibitors
- MacKay, Simon (Principal Investigator)
- 01-Jan-2018 - 31-Jan-2018
- David Begg / NSF Studentship | Webb, Cameron
- Perrie, Yvonne (Principal Investigator) MacKay, Simon (Co-investigator) Webb, Cameron (Research Co-investigator)
- 01-Jan-2018 - 16-Jan-2022
- Prevention of CXCL12 production in cells of the cardiovascular system by IKK alpha inhibition (BHF PhD Studentship)
- Plevin, Robin (Principal Investigator) Coats, Paul (Co-investigator) MacKay, Simon (Co-investigator) Paul, Andrew (Co-investigator)
- 01-Jan-2018 - 30-Jan-2022
- Identification of pre-clinical SK1 inhibitors for the treatment of Pulmonary Hypertension
- Pyne, Nigel (Principal Investigator) MacKay, Simon (Co-investigator) Pyne, Susan (Co-investigator)
- 26-Jan-2013 - 25-Jan-2014
Back to staff profile
Contact
Professor
Simon
MacKay
Strathclyde Institute of Pharmacy and Biomedical Sciences
Email: simon.mackay@strath.ac.uk
Tel: 548 2866