Publications

Mitochondria regulate inositol triphosphate‐mediated Ca 2+ release triggered by voltage‐dependent Ca 2+ entry in resistance arteries : Ca2+ entry activates IP3 receptors in smooth muscle

Zhang Xun, Buckley Charlotte, Lee Matthew D, Chalmers Susan, Wilson Calum, McCarron John G

The Journal of Physiology Vol 603, pp. 2959-2978 (2025)

https://doi.org/10.1113/JP288022

Increased TRPV4 channel expression enhances and impairs blood vessel function in hypertension

Zhang Xun, Buckley Charlotte, Lee Matthew D, Salaun Christine, MacDonald Margaret, Wilson Calum, McCarron John G

Hypertension Vol 82, pp. 57-68 (2025)

https://doi.org/10.1161/HYPERTENSIONAHA.124.23092

Signalling switches maintain intercellular communication in the vascular endothelium : endothelial Ca2+ waves driven by regenerative IP3-induced IP3 production

Buckley Charlotte, Lee Matthew D, Zhang Xun, Wilson Calum, McCarron John G

British Journal of Pharmacology Vol 181, pp. 2810-2832 (2024)

https://doi.org/10.1111/bph.16366

Signaling switches maintain intercellular communication in the vascular endothelium

Buckley Charlotte, Lee Matthew, Zhang Xun, Wilson Calum, McCarron John

Physiology Vol 39 (2024)

https://doi.org/10.1152/physiol.2024.39.s1.1480

Mitochondria control IP₃-evoked Ca²⁺ release triggered by voltage-dependent Ca²⁺ entry in intact resistance arteries

Zhang Xun, Lee Matthew, Buckley Charlotte, Wilson Calum, McCarron John

Physiology Vol 39 (2024)

https://doi.org/10.1152/physiol.2024.39.s1.1739

Simultaneous arrival of multiple agonists : how the endothelium senses and responds

Lee Matthew, Wilson Calum, Buckley Charlotte, Zhang Xun, Woodsend Cian, Osborne Christopher, McCarron John

Physiology Vol 39 (2024)

https://doi.org/10.1152/physiol.2024.39.s1.1545

More publications

Professional Activities

FASEB Smooth Muscle conference.

Keynote/plenary speaker

2019

11th World Congress for Microcirculation

Keynote/plenary speaker

2018

EuroPhysiology conference

Keynote/plenary speaker

2018

Swarm Intelligence in endothelial signalling

Invited speaker

2018

19th Imperial College London International Symposium

Keynote/plenary speaker

23/11/2017

International Symposium for Resistance Arteries

Organiser

2017

More professional activities

Projects

A multicellular endothelial signalling web coordinates vascular function and is impaired in hypertension

McCarron, John (Principal Investigator) Buckley, Charlotte (Co-investigator) Wilson, Calum (Co-investigator)

19-Jan-2021 - 18-Jan-2026

Mitochondrial amplification of local calcium entry and vascular contraction in hypertension

McCarron, John (Principal Investigator) Buckley, Charlotte (Co-investigator) Chalmers, Susan (Co-investigator) Wilson, Calum (Co-investigator)

Mitochondrial control of voltage-dependent calcium entry in hypertension

03-Jan-2020 - 08-Jan-2024

Optical Cannula: Development of a tool for studying the inside of tubular organs under physiologically relevant conditions by imaging from within

McCarron, John (Principal Investigator)

01-Jan-2017 - 18-Jan-2021

ENDOTHELIAL Ca2+ SIGNALLING IN HYPERTENSION VISUALIZED FROM INSIDE PRESSURIZED ARTERIES

McCarron, John (Principal Investigator) Wilson, Calum (Co-investigator)

01-Jan-2017 - 03-Jan-2021

Endothelial acetylcholine release explains flow mediated dilation and is impaired in type 2 diabetes

McCarron, John (Principal Investigator) Wilson, Calum (Co-investigator)

Endothelial acetylcholine release accounts for flow-mediated dilation and is impaired in type 2 diabetes

09-Jan-2017 - 25-Jan-2020

EPSRC Centre for Doctoral Training in Medical Devices and Health Technologies | Ratnayake, Manuela

Ratnayake, Manuela (Research Co-investigator) McCarron, John (Principal Investigator) Sandison, Mairi (Co-investigator)

01-Jan-2014 - 01-Jan-2018

More projects