Publications

Increased TRPV4 channel expression enhances and impairs blood vessel function in hypertension

Zhang Xun, Buckley Charlotte, Lee Matthew D, Salaun Christine, MacDonald Margaret, Wilson Calum, McCarron John G

Hypertension (2024)

https://doi.org/10.1161/HYPERTENSIONAHA.124.23092

Signalling switches maintain intercellular communication in the vascular endothelium : endothelial Ca2+ waves driven by regenerative IP3-induced IP3 production

Buckley Charlotte, Lee Matthew D, Zhang Xun, Wilson Calum, McCarron John G

British Journal of Pharmacology Vol 181, pp. 2810-2832 (2024)

https://doi.org/10.1111/bph.16366

Endothelial Membrane Potential Changes are Required for Propagated Vasodilation

Woodsend Cian, Buckley Charlotte, Zhang Xun, Wilson Calum, Lee Matthew, McCarron John

Physiology Vol 39 (2024)

https://doi.org/10.1152/physiol.2024.39.s1.2016

Mitochondria control IP₃-evoked Ca²⁺ release triggered by voltage-dependent Ca²⁺ entry in intact resistance arteries

Zhang Xun, Lee Matthew, Buckley Charlotte, Wilson Calum, McCarron John

Physiology Vol 39 (2024)

https://doi.org/10.1152/physiol.2024.39.s1.1739

Signaling switches maintain intercellular communication in the vascular endothelium

Buckley Charlotte, Lee Matthew, Zhang Xun, Wilson Calum, McCarron John

Physiology Vol 39 (2024)

https://doi.org/10.1152/physiol.2024.39.s1.1480

Simultaneous arrival of multiple agonists : how the endothelium senses and responds

Lee Matthew, Wilson Calum, Buckley Charlotte, Zhang Xun, Woodsend Cian, Osborne Christopher, McCarron John

Physiology Vol 39 (2024)

https://doi.org/10.1152/physiol.2024.39.s1.1545

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Professional Activities

FASEB Smooth Muscle conference.

Keynote/plenary speaker

2019

Swarm Intelligence in endothelial signalling

Invited speaker

2018

11th World Congress for Microcirculation

Keynote/plenary speaker

2018

EuroPhysiology conference

Keynote/plenary speaker

2018

19th Imperial College London International Symposium

Keynote/plenary speaker

23/11/2017

International Symposium for Resistance Arteries

Organiser

2017

More professional activities

Projects

A multicellular endothelial signalling web coordinates vascular function and is impaired in hypertension

McCarron, John (Principal Investigator) Buckley, Charlotte (Co-investigator) Wilson, Calum (Co-investigator)

19-Jan-2021 - 18-Jan-2026

Mitochondrial amplification of local calcium entry and vascular contraction in hypertension

McCarron, John (Principal Investigator) Buckley, Charlotte (Co-investigator) Chalmers, Susan (Co-investigator) Wilson, Calum (Co-investigator)

Mitochondrial control of voltage-dependent calcium entry in hypertension

03-Apr-2020 - 08-Jan-2024

Optical Cannula: Development of a tool for studying the inside of tubular organs under physiologically relevant conditions by imaging from within

McCarron, John (Principal Investigator)

01-Apr-2017 - 18-May-2021

ENDOTHELIAL Ca2+ SIGNALLING IN HYPERTENSION VISUALIZED FROM INSIDE PRESSURIZED ARTERIES

McCarron, John (Principal Investigator) Wilson, Calum (Co-investigator)

01-Feb-2017 - 03-Sep-2021

Endothelial acetylcholine release explains flow mediated dilation and is impaired in type 2 diabetes

McCarron, John (Principal Investigator) Wilson, Calum (Co-investigator)

Endothelial acetylcholine release accounts for flow-mediated dilation and is impaired in type 2 diabetes

09-Jan-2017 - 25-May-2020

EPSRC Centre for Doctoral Training in Medical Devices and Health Technologies | Ratnayake, Manuela

Ratnayake, Manuela (Research Co-investigator) McCarron, John (Principal Investigator) Sandison, Mairi (Co-investigator)

01-Oct-2014 - 01-Oct-2018

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