Professor John McCarron

Strathclyde Institute of Pharmacy and Biomedical Sciences

Publications

MYC regulates fatty acid metabolism through a multigenic program in claudin-low triple negative breast cancer
Casciano Jessica C, Perry Caroline, Cohen-Nowak Adam J, Miller Katelyn D, Voorde Johan Vande, Zhang Qifeng, Chalmers Susan, Sandison Mairi E, Lui Qin, Hedley Ann, McBryan Tony, Tang Hsin-Yao, Gorman Nicole, Beer Thomas, Speicher David W, Adams Peter D, Lui Xuefeng, Schlegel Richard, McCarron John G, Wakelam Michael J O, Gottlieb Eyal, Kossenkov Andrew V, Schug Zachary T
British Journal of Cancer (2020)
https://doi.org/10.1038/s41416-019-0711-3
Hydrogen peroxide depolarizes mitochondria and inhibits IP3-evoked Ca2+ release in the endothelium of intact arteries
Zhang Xun, Lee Matthew D, Wilson Calum, McCarron John G
Cell Calcium Vol 84 (2019)
https://doi.org/10.1016/j.ceca.2019.102108
FK506 regulates IP3 evoked Ca2+ release independently of FKBP in endothelial cells
Buckley Charlotte, Wilson Calum, McCarron John G
British Journal of Pharmacology (2019)
https://doi.org/10.1111/bph.14905
Multi-plane remote refocussing epifluorescence microscopy to image dynamic Ca2+ events
Lawton Penelope F, Buckley Charlotte, Saunter Christopher D, Wilson Calum, Corbett Alexander D, Slater Patrick S, McCarron John G, Girkin John M
Biomedical Optics Express Vol 10, pp. 5611-5624 (2019)
https://doi.org/10.1364/BOE.10.005611
Endothelial TRPV4 channels modulate vascular tone by Ca 2+-induced Ca 2+ release at inositol 1,4,5-trisphosphate receptors
Heathcote Helen R, Lee Matthew D, Zhang Xun, Saunter Christopher D, Wilson Calum, McCarron John G
British Journal of Pharmacology Vol 176, pp. 3297-3317 (2019)
https://doi.org/10.1111/bph.14762
Increased vascular contractility in hypertension results from impaired endothelial calcium signaling
Wilson Calum, Zhang Xun, Buckley Charlotte, Heathcote Helen R, Lee Matthew D, McCarron John G
Hypertension Vol 74, pp. 1200-1214 (2019)
https://doi.org/10.1161/HYPERTENSIONAHA.119.13791

more publications

Professional activities

19th Imperial College London International Symposium
Keynote/plenary speaker
23/11/2017
International Symposium for Resistance Arteries
Organiser
2017
British Pharmacological Society
Invited speaker
21/9/2016
FASEB conference on smooth muscle,
Keynote/plenary speaker
16/7/2016
Experimental Biology
Keynote/plenary speaker
1/4/2016
Experimental Biology
Keynote/plenary speaker
29/3/2015

more professional activities

Projects

Optical Cannula: Development of a tool for studying the inside of tubular organs under physiologically relevant conditions by imaging from within
McCarron, John (Principal Investigator)
01-Jan-2017 - 18-Jan-2020
ENDOTHELIAL Ca2+ SIGNALLING IN HYPERTENSION VISUALIZED FROM INSIDE PRESSURIZED ARTERIES
McCarron, John (Principal Investigator) Wilson, Calum (Co-investigator)
01-Jan-2017 - 31-Jan-2020
Endothelial acetylcholine release explains flow mediated dilation and is impaired in type 2 diabetes
McCarron, John (Principal Investigator) Wilson, Calum (Co-investigator)
09-Jan-2017 - 25-Jan-2020
EPSRC Centre for Doctoral Training in Medical Devices and Health Technologies | Ratnayake, Manuela
Ratnayake, Manuela (Research Co-investigator) McCarron, John (Principal Investigator) Sandison, Mairi (Co-investigator)
01-Jan-2014 - 01-Jan-2018
BTG: Investigating vascular cell fate using micro-patterned cell arrays and extended time-lapse imaging
Sandison, Mairi (Principal Investigator) McCarron, John (Co-investigator) Zagnoni, Michele (Co-investigator)
Cardiovascular disease occurs when blood vessel structure changes through proliferation of cells in the vessel wall. The source of these cells is the vessel itself but precisely which cell(s) proliferate is unclear. Understanding their origins is a prerequisite for informed development of treatment. To investigate this, we will combine micro-patterned cell array technologies with long-term, timelapse imaging to develop new approaches for simultaneously monitoring the fate of large numbers of cells obtained from vascular cell isolations. Array architectures will be created to isolate the various cell types, probe cell-cell interactions and investigate how these interactions affect cellular differentiation and proliferation.
17-Jan-2014 - 14-Jan-2014
Medical Devices Doctoral Training Centre Renewal | Kaloya, Sukhraj
McCormick, Christopher (Principal Investigator) McCarron, John (Co-investigator) Kaloya, Sukhraj (Research Co-investigator)
01-Jan-2013 - 01-Jan-2017

more projects

Address

Strathclyde Institute of Pharmacy and Biomedical Sciences
Robertson Wing

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